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https://www.readbyqxmd.com/read/30306533/making-a-picture-worth-a-thousand-numbers-recommendations-for-graphically-displaying-patient-reported-outcomes-data
#1
Claire Snyder, Katherine Smith, Bernhard Holzner, Yonaira M Rivera, Elissa Bantug, Michael Brundage
PURPOSE: Patient-reported outcomes (PROs) can promote patient-centered care in multiple ways: (1) using an individual patient's PRO data to inform his/her management, (2) providing PRO results from comparative research studies in patient educational materials/decision aids, and (3) reporting PRO results from comparative research studies in peer-reviewed publications. Patients and clinicians endorse the value of PRO data; however, variations in how PRO measures are scored and scaled, and in how the data are reported, make interpretation challenging and limit their use in clinical practice...
October 10, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/30274872/a-pathway-to-publishing-an-oncology-nursing-book
#2
REVIEW
Patricia C Buchsel, Lisa Schulmeister
OBJECTIVES: To describe the process of book publishing, including authoring and revising book chapters, and provide resources on book publishing opportunities for oncology nurses. DATA SOURCES: Journal articles, book publishers' information for authors, online publishing resources, discussions with textbook editors, personal experience. CONCLUSION: Few published resources exist to guide nurses as they author and/or revise books and book chapters...
November 2018: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/29763267/top-20-research-studies-of-2017-for-primary-care-physicians
#3
Mark H Ebell, Roland Grad
Based on systematic surveillance of more than 110 medical journals, 247 studies met criteria as POEMs (patient-oriented evidence that matters) in 2017. Members of the Canadian Medical Association identified 20 of these POEMs as most relevant to practice. This article reviews the clinical questions and bottom-line answers from these studies. Blood pressure should be measured after a period of rest, using a bare arm, and orthostatic blood pressure is more predictive when measured after one minute of standing rather than three minutes...
May 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29762260/clinical-indications-associated-with-opioid-initiation-for-pain-management-in-ontario-canada-a-population-based-cohort-study
#4
Sachin V Pasricha, Mina Tadrous, Wayne Khuu, David N Juurlink, Muhammad M Mamdani, J Michael Paterson, Tara Gomes
Concerns over prescription opioids contributing to high levels of opioid use disorder and overdose have led policymakers and clinicians to seek means to reduce inappropriate and high-dose initial prescriptions. To inform such efforts, we sought to describe the clinical indications associated with opioid initiation and the characteristics of the initial prescriptions and patients through a retrospective population-based cohort study. Our cohort included Ontarians initiating prescription opioids for pain management between April 1, 2015, and March 31, 2016...
August 2018: Pain
https://www.readbyqxmd.com/read/29757870/changing-clinical-practice-evaluation-of-implementing-recommendations-for-opportunistic-salpingectomy-in-british-columbia-and-ontario
#5
Bryn Lander, Elizabeth Wilcox, Jessica N McAlpine, Sarah J Finlayson, David G Huntsman, Dianne Miller, Gillian E Hanley
OBJECTIVE: The aim of the study was to explore the factors that contributed to the adoption of opportunistic salpingectomies (removal of fallopian at the time of hysterectomy or in lieu of tubal ligation) by gynecologic surgeons in British Columbia (where a knowledge translation initiative took place) and in Ontario (a comparator where no knowledge translation initiative took place). We aimed to understand why the knowledge translation initiative undertaken by OVCARE in British Columbia resulted in such a dramatic uptake in opportunistic salpingectomy...
July 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29697603/validated-outcomes-in-the-grafting-of-autologous-fat-to-the-breast-the-vogue-study-development-of-a-core-outcome-set-for-research-and-audit
#6
Riaz A Agha, Thomas E Pidgeon, Mimi R Borrelli, Naeem Dowlut, Ter-Er K Orkar, Maziyah Ahmed, Ojas Pujji, Dennis P Orgill
BACKGROUND: Autologous fat grafting is an important part of the reconstructive surgeon's toolbox when treating women affected by breast cancer and subsequent tumor extirpation. The debate over safety and efficacy of autologous fat grafting continues within the literature. However, work performed by the authors' group has shown significant heterogeneity in outcome reporting. Core outcome sets have been shown to reduce heterogeneity in outcome reporting. The authors' goal was to develop a core outcome set for autologous fat grafting in breast reconstruction...
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29669583/protocol-for-a-systematic-review-and-thematic-synthesis-of-patient-experiences-of-central-venous-access-devices-in-anti-cancer-treatment
#7
Caoimhe Ryan, Hannah Hesselgreaves, Olivia Wu, Jim Paul, Judith Dixon-Hughes, Jonathan G Moss
BACKGROUND: Three types of central venous access devices (CVADs)-peripherally inserted central catheters (PICCs), skin-tunnelled central catheters (Hickman-type devices), and implantable chest wall Ports (Ports)-are routinely used in the intravenous administration of anti-cancer treatment. These devices avoid the need for peripheral cannulation and allow for home delivery of treatment. Assessments of these devices have tended to focus on medical and economic factors, but there is increased interest in the importance of patient experiences and perspectives in this area...
April 18, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29650060/gastrostomy-versus-nasogastric-tube-feeding-for-chemoradiation-patients-with-head-and-neck-cancer-the-tube-pilot-rct
#8
Vinidh Paleri, Joanne Patterson, Nikki Rousseau, Eoin Moloney, Dawn Craig, Dimitrios Tzelis, Nina Wilkinson, Jeremy Franks, Ann Marie Hynes, Ben Heaven, David Hamilton, Teresa Guerrero-Urbano, Rachael Donnelly, Stewart Barclay, Tim Rapley, Deborah Stocken
BACKGROUND: Approximately 9000 new cases of head and neck squamous cell cancers (HNSCCs) are treated by the NHS each year. Chemoradiation therapy (CRT) is a commonly used treatment for advanced HNSCC. Approximately 90% of patients undergoing CRT require nutritional support via gastrostomy or nasogastric tube feeding. Long-term dysphagia following CRT is a primary concern for patients. The effect of enteral feeding routes on swallowing function is not well understood, and the two feeding methods have, to date (at the time of writing), not been compared...
April 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29556926/nutrition-impact-symptoms-and-associated-outcomes-in-post-chemoradiotherapy-head-and-neck-cancer-survivors-a-systematic-review
#9
REVIEW
Sylvia L Crowder, Katherine G Douglas, M Yanina Pepino, Kalika P Sarma, Anna E Arthur
PURPOSE: It is estimated that more than 90% of head and neck cancer (HNC) survivors who underwent chemoradiotherapy experience one or more nutrition impact symptoms (NIS) in the months or years thereafter. Despite the high prevalence, there is limited research addressing long-term impact of NIS on outcomes such as nutrition and quality of life in HNC survivors treated with chemoradiotherapy. OBJECTIVE: To conduct a systematic review of the literature pertaining to the presence of nutrition impact symptoms and their associated outcomes in post-chemoradiotherapy head and neck cancer survivors...
August 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29456624/the-case-for-a-regional-approach-to-publication-impact
#10
EDITORIAL
Stevan Bruijns, Camillo Lamanna
Healthcare-related research is largely regional. Put simply, this is because disease burdens differ between world regions. Even global burdens, such as ischaemic heart disease and cancer, display distinctive characteristics in certain regions that are not seen in others. Regional differences in infrastructure, resources and human capital further compound the differences seen, as they affect the way in which the local scientific community can interact with the local disease burden. As such, it seems fair to assume that healthcare-related research ought to be regionally distributed...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29411148/from-a-patient-advocate-s-perspective-does-cancer-immunotherapy-represent-a-paradigm-shift
#11
REVIEW
Debra L Madden
PURPOSE OF REVIEW: In 2016, the American Society of Clinical Oncology (ASCO) announced immunotherapy as the year's top cancer advance in its "Clinical Cancer Advances 2016: ASCO's Annual Report on Progress Against Cancer." Further, ASCO again named "Immunotherapy 2.0" as the 2017 advance of the year, emphasizing the recent, rapid pace of research into new agents that harness and enhance the innate abilities of the immune system to recognize and fight cancers-and stressing that such agents have extended the lives of many patients with late-stage cancers for which there have been few treatment options...
February 7, 2018: Current Oncology Reports
https://www.readbyqxmd.com/read/29374660/blood-based-biomarkers-of-cancer-related-cognitive-impairment-in-non-central-nervous-system-cancer-protocol-for-a-scoping-review
#12
REVIEW
Samantha J Mayo, John Kuruvilla, Rob C Laister, Ana Patricia Ayala, Mark Alm, Will Byker, Debra Lynch Kelly, Leorey Saligan
INTRODUCTION: Cancer-related cognitive impairment (CRCI) can have detrimental effects on quality of life, even among patients with non-central nervous system (CNS) cancers. Several studies have been conducted to explore different markers associated with CRCI to understand its pathobiology. It is proposed that the underlying mechanisms of CRCI are related to a cascade of physiological adaptive events in response to cancer and/or treatment. Hence, peripheral blood would be a logical source to observe and identify these physiological events...
January 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29355883/optimizing-pain-management-through-opioid-deprescribing
#13
Rachel Lumish, Joshana K Goga, Nicole J Brandt
The use of opioid drug therapy in older adults has increased over the past decade. Although use of opioid drugs may be clinically warranted, ongoing use needs to be monitored closely to evaluate risks and benefits, especially with the potential for adverse events and misuse. An opioid drug deprescribing protocol would provide clinicians with a method to assess an individual's need for opioid agents, as well as a systematic process to taper opioid drug therapy when deemed appropriate. Although more than 60 studies have reported methods for deprescribing, there is currently no established guideline for discontinuing opioid medications...
January 1, 2018: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/29282737/from-bad-to-worse-when-lung-cancer-complicates-idiopathic-pulmonary-fibrosis
#14
Stephen B Strock, Jonathan K Alder, Daniel J Kass
Patients with idiopathic pulmonary fibrosis have a significantly increased risk for the development of lung cancer. The morbidity and mortality of this disease combination are substantial, and, unfortunately, there are currently few data to help guide clinicians in its diagnosis and treatment. In a recent issue of this journal, Hwang et al presented one of the first studies to evaluate lung cancer in patients with idiopathic pulmonary fibrosis at the molecular level. They demonstrate variants in regulators of the cell cycle, which are known to be important in malignant transformation and may also be important in the pathogenesis of idiopathic pulmonary fibrosis...
April 2018: Journal of Pathology
https://www.readbyqxmd.com/read/29261818/update-in-hospital-palliative-care-symptom-management-communication-caregiver-outcomes-and-moral-distress
#15
Rachel D Havyer, Daniel H Pomerantz, Robert L Jayes, Patricia F Harris, Stephanie M Harman, Aziz A Ansari
BACKGROUND: Updated knowledge of the palliative care (PC) literature is needed to maintain competency and best address the PC needs of hospitalized patients. We critiqued the recent PC literature with the highest potential to impact hospital practice. METHODS: We reviewed articles published between January 2016 and December 2016, which were identified through a handsearch of leading journals and a MEDLINE search. The final 9 articles selected were determined by consensus based on scientific rigor, relevance to hospital medicine, and impact on practice...
June 1, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29233804/end-user-and-implementer-experiences-of-mhealth-technologies-for-noncommunicable-chronic-disease-management-in-young-adults-systematic-review
#16
REVIEW
Helen Slater, Jared M Campbell, Jennifer N Stinson, Megan M Burley, Andrew M Briggs
BACKGROUND: Chronic noncommunicable diseases (NCDs) such as asthma, diabetes, cancer, and persistent musculoskeletal pain impose an escalating and unsustainable burden on young people, their families, and society. Exploring how mobile health (mHealth) technologies can support management for young people with NCDs is imperative. OBJECTIVE: The aim of this study was to identify, appraise, and synthesize available qualitative evidence on users' experiences of mHealth technologies for NCD management in young people...
December 12, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29118960/from-the-padua-muscle-days-the-basic-and-applied-myology-and-the-european-journal-of-translational-myology-to-the-a-cm-carraro-foundation-for-translational-myology
#17
Ugo Carraro
As a young researched I had the option to work on skeletal muscle at the University of Padova, Italy. Introduced to the study of muscle denervation/reinnervation, I started a project on long term denervated muscle that still is my primary interest and took me from rodents' models of chronic muscle denervation to human spinal cord injury-related muscle denervation and its managements. On the way, I organized a series of conferences in Euganei Hills, Padua, Italy and an international journal, the Basic and Applied Myology...
June 27, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28723431/clinical-perspectives-from-randomized-phase-3-trials-on-prostate-cancer-an-analysis-of-the-clinicaltrials-gov-database
#18
Alexandros Tsikkinis, Nikola Cihoric, Gianluca Giannarini, Stefan Hinz, Alberto Briganti, Peter Wust, Piet Ost, Guillaume Ploussard, Christophe Massard, Cristian I Surcel, Prasanna Sooriakumaran, Hendrik Isbarn, Peter J L De Visschere, Jurgen J Futterer, Roderick C N van der Bergh, Alan Dal Pra, Daniel M Aebersold, Volker Budach, Pirus Ghadjar
BACKGROUND: It is not easy to overview pending phase 3 trials on prostate cancer (PCa), and awareness of these trials would benefit clinicians. OBJECTIVE: To identify all phase 3 trials on PCa registered in the ClinicalTrials.gov database with pending results. DESIGN AND SETTING: On September 29, 2014, a database was established from the records for 175 538 clinical trials registered on ClinicalTrials.gov. A search of this database for the substring "prostat" identified 2951 prostate trials...
September 2015: European Urology Focus
https://www.readbyqxmd.com/read/28475407/diagnosis-staging-and-risk-stratification-in-prostate-cancer-utilizing-diagnostic-tools-to-avoid-unnecessary-therapies-and-side-effects
#19
Louis Rodgers, Cody J Peer, William D Figg
A lack of appropriate diagnostic tools for prostate cancer has led to overdiagnosis and over treatment. In a recent publication in the New England Journal of Medicine, Hamdy et al showed no difference in the outcomes of patients that had undergone either radical prostatectomy, radiotherapy, or active monitoring. In an effort to enhance clinical stratification, the development of improved, more accurate diagnostic tools is actively being pursued. Herein, we explore recent advances in prostate cancer screening, including biomarker assays, genetic testing, and specialized fields, such as mathematical oncology...
July 3, 2017: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/27840359/the-risk-factors-of-prostate-cancer-and-its-prevention-a-literature-review
#20
REVIEW
Noor Riza Perdana, Chaidir A Mochtar, Rainy Umbas, Agus Rizal Ah Hamid
This is a literature review study. Data was obtained from several literature reviews and journal resources that have correlation with the risk factors involved in PCa including age, ethnicity, family history, insulin-Like growth factor, sexually transmitted disease, obesity, smoking, alcohol consumption, vasectomy, and diet, and the prevention of PCa including soy, lycopene, green tea, supplementation, and exercise.Numerous epidemiologic studies have linked PCa risk to various factors, i.e. age, ethnicity, family history, insulin like-growth factors, lifestyle, diet, environmental and occupational exposures...
July 2016: Acta Medica Indonesiana
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