Read by QxMD icon Read

Neurological cases

Genaro Castillon, Francesco Salvo, Yola Moride
INTRODUCTION: Some adverse drug reactions (ADRs) may involve direct social issues, such as impaired quality of life, work productivity, or social functioning, as opposed to being social consequences of medical adverse events. Data on ADRs with a direct social impact remain scarce in the literature. OBJECTIVE: Our objective was to describe the ADRs consisting of direct social issues that have been recorded in the Canadian national spontaneous reporting system (Canada Vigilance)...
August 19, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Thomas M Zervos, Adam M Robin, Ian Lee
Since there is no cure for glioblastoma multiforme (GBM), the goal of treatment becomes prolonging the survival through cytoreduction while minimising neurological deficits. In this case report, laser interstitial thermal therapy (LITT) was used once the tumour progressed into the isthmus of the cingulate gyrus. One year after temporal lobectomy, disorders of memory, emotion, personality and navigation, likely related to limbic system involvement along with hallucinations and fluctuating cognition occurred as the tumour progressed...
August 17, 2018: BMJ Case Reports
Huiliang Yang, Akash A Shah, Sandra B Nelson, Joseph H Schwab
BACKGROUND CONTEXT: Fungal spinal epidural abscess (FSEA) is a rare entity with high morbidity and mortality. Reports describing the clinical features, diagnosis, treatment, and outcomes of FSEA are scarce in the literature. PURPOSE: This study aimed to describe the clinical features, diagnosis, treatment and outcomes of FSEA. STUDY DESIGN: This study is designed as a retrospective clinical case series. PATIENT SAMPLE: A continuous series of patients with the diagnosis of FSEA who presented at our institution from 1993 to 2016...
August 16, 2018: Spine Journal: Official Journal of the North American Spine Society
Aishwarya Kakade, Baby Kumari, Pankaj Singh Dholaniya
Parkinson's Disease (PD) is described as a progressive neurological disorder caused by the degeneration of dopaminergic neurons in substantia nigra pars compacta. The pathogenesis of the disease is not fully understood but it has been linked with complex genetic, epigenetic and environmental interactions. A substantial number of studies have shown the role of epigenetic modifications in support of the progression of PD. In the present study, we have analyzed the data containing methylation patterns of 1726 transcripts captured over from 66 samples of 450k, which includes 43 controls and 23 diseased samples...
August 15, 2018: Journal of Theoretical Biology
Yasemin Eren, Naciye Kabatas, Hayat Guven, Selcuk Comoglu, Canan Gurdal
In the case of mild papilledema, fundoscopy findings may sometimes be insufficient, leading to false and misleading indices in the diagnosis of early-stage idiopathic intracranial hypertension (IIH). This study aims to evaluate these patients through optic coherence tomography (OCT). The study included 54 individuals diagnosed with IIH and 48 healthy individuals in the control group. All patients underwent neurological and ophthalmologic examinations. Opening pressure values of patients' cerebrospinal fluid (CSF) were recorded...
August 17, 2018: Acta Neurologica Belgica
Ronette Goodluck Tyndall, Oana-Eugenia Popescu, Prevost Derek, Paul Steinbok
BACKGROUND: Osteogenic sarcoma of the skull is uncommon and long-term outcome is not well defined. We review the literature and present a pediatric case of calvarial osteogenic sarcoma with good long-term oncological and cosmetic outcome and excellent quality of life. This case presented major surgical challenges, which are detailed. CASE DESCRIPTION: A 6-year-old boy presented with a painless 5 cm × 5 cm lump over the vertex region. He was neurologically normal...
August 17, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
W Druml
The central role of the organ system "gut" for critically ill patients has not been acknowledged until the last decade. The gut is a crucial immunologic, metabolic and neurologic organ system and impairment of its functions is associated with morbidity and mortality. The gut has a central position in the cross-talk between organs and dysfunction of the gut may result in impairment of other intra-abdominal and extra-abdominal organ systems. The intestinal tract is the most important source of endogenous infections and determines the inflammatory status of the organism...
August 17, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
Carmen Regla Vargas, Graziela Schmitt Ribas, Janine Machado da Silva, Angela Sitta, Marion Deon, Daniella de Moura Coelho, Moacir Wajner
BACKGROUND: Inborn errors of metabolism (IEM) are diseases which can lead to accumulation of toxic metabolites in the organism. AIM OF THE STUDY: To investigate, by selective screening, mitochondrial fatty acid oxidation defects (FAOD) and organic acidemias in Brazilian individuals with clinical suspicion of IEM. METHODS: A total of 7,268 individuals, from different regions of Brazil, had whole blood samples impregnated on filter paper which were submitted to the acylcarnitines analysis by liquid chromatography/tandem mass spectrometry (LC/MS/MS) at the Medical Genetics Service of Hospital de Clínicas de Porto Alegre, Brazil, during July 2008-July 2016...
August 14, 2018: Archives of Medical Research
Tomoya Kawazoe, Toshiyuki Yamamoto, Aya Narita, Kousaku Ohno, Kaori Adachi, Eiji Nanba, Atsuko Noguchi, Tsutomu Takahashi, Masamitsu Maekawa, Yoshikatsu Eto, Masafumi Ogawa, Miho Murata, Yuji Takahashi
BACKGROUND: Niemann-Pick disease type C (NPC) is a lysosomal storage disorder with severe prognosis. Disease-specific therapy is crucial to prevent disease progression; however, diagnosing NPC is quite difficult because of remarkably variable clinical presentations. The NPC Suspicion Index (NPC-SI) was developed to overcome this problem. Identifying preclinical cases is important for prevention and therapy. Here, we report three newly diagnosed NPC cases, one typical juvenile-onset case and the cases of two sisters with symptoms neurologically/psychiatrically indistinguishable from dystonia and schizophrenia, respectively...
August 17, 2018: BMC Neurology
Seok Won Kim, Choon-Mee Kim, Dong-Min Kim, Na Ra Yun
BACKGROUND: Human granulocytic anaplasmosis is a tick-borne zoonotic disease caused by Anaplasma phagocytophilum, an obligate intracellular granulocytotropic bacterium. CASE PRESENTATION: A 70-year-old female patient was admitted with the clinical signs of fever and an altered state of consciousness 1 week after experiencing a tick bite while planting lawn grass. Magnetic resonance imaging, performed at the time of admission, indicated cerebral infarction in the left basal ganglia, whereas increasing immunofluorescence assay antibody titers for A...
August 17, 2018: BMC Infectious Diseases
Paulo N Martins, Isabel M A Brüggenwirth, James McDaid, Martin Hertl, Tatsuo Kawai, Nahel Elias, Raymond T Chung, James F Markmann
Heat stroke is a multiple organ dysfunction syndrome of poorly understood pathogenesis. Exertional heat stroke with acute liver failure is a rarely reported condition. Liver transplant has been recommended as treatment in cases of severe liver dysfunction; however, there are only 5 described cases of long-term survival after this procedure in patients with heat stroke. Here, we present 2 cases of young athletes who developed heat stroke. Both patients developed acute liver failure and were listed for liver transplant...
August 17, 2018: Experimental and Clinical Transplantation
Seyed Mohsen Dehghani, Mahmood Haghighat, Farideh Nematollahi, Hazhir Javaherizadeh, Naser Honar, Maryam Bahmanyar, Maryam Ataollahi
INTRODUCTION: The aim of this study was to evaluate complications after percutaneous endoscopic gastrostomy among children who underwent percutaneous endoscopic gastrostomy in Nemazee hospital. MATERIALS AND METHODS: All children who underwent percutaneous endoscopic gastrostomy were included in the current study. Place of the study was department of pediatric gastroenterology of Nemazee children hospital of Shiraz university of medical sciences. Duration of the study was 5 year starting from 2008...
April 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Seunggu J Han, Ramin A Morshed, Irene Troncon, Kesshi M Jordan, Roland G Henry, Shawn L Hervey-Jumper, Mitchel S Berger
OBJECTIVE Herein, the authors report their experience with intraoperative stimulation mapping to locate the descending subcortical motor pathways in patients undergoing surgery for hemispheric gliomas within or adjacent to the rolandic cortex, with particular description of the morbidity and functional outcomes associated with this technique. METHODS This is a retrospective analysis of patients who, in the period between 1997 and 2016, had undergone resection of hemispheric perirolandic gliomas within or adjacent to descending motor pathways...
August 17, 2018: Journal of Neurosurgery
Joel Haakon Borgstedt-Bakke, Peter Duel, Mikkel Mylius Rasmussen
We present a case of a 55-year-old farmer who suddenly experienced an electric sensation in the left half of his body during lawn mowing. Neurological examination discovered neurological deficits corresponding to an incomplete spinal cord injury. Magnetic resonance imaging displayed an artifact in the cervical region. Following, a computer tomography imaging showed a metal object, located intramedullary, in the cervical spinal cord. The conclusion was a traumatic lesion from the metal object obtained during lawn mowing...
August 17, 2018: Acta Neurochirurgica
Changsong Xu, Bing Chen, Liujun Xue, Lei Xia, Xiu Yang, Ming Wei, Xiaobo Hui, Quan Chen, Jinlong Zheng, Zhengming Li, Xiangyang Tian, Guanliang Cheng, Feng Xiao, Min Lu
The present randomized controlled study investigated the differences in the curative effects of twist-drill craniotomy (TDC) and burr-hole craniotomy (BHC) in the treatment of chronic subdural hematoma (CSDH). A total of 40 patients diagnosed with CSDH via head computed tomography (CT) who required surgical decompression from January 2016 to January 2017 were enrolled in the present study, and were randomly divided into a TDC group (n=20) and a BHC group (n=20). The modified Rankin scale (mRS) scores of patients were recorded prior to the operation, and at 48 h and 3 months after the operation...
August 2018: Experimental and Therapeutic Medicine
Sezen Ugan Atik, Firuze Erbek Alp, Reyhan Dedeoğlu, Aida Koka, Funda Öztunç, Ayşe Güler Eroğlu
Catecholaminergic polymorphic ventricular tachycardia is a rhythm disorder that develops due to genetic reasons in the absence of structural cardiac abnormalities. Ventricular tachycardia, ventricular fibrillation, cardiac arrest, and death may occur. Two-year-old patient presented to the Emergency Department with sudden cardiac arrest. He had syncope attacks after playing with his brother and he was followed up by the pediatric neurology and cardiology clinics. Cardiopulmonary resuscitation was performed, and he was then transferred to the Intensive Care Unit because of hypotension; dobutamine and norepinephrine treatment was started...
June 2018: Türk Pediatri Arşivi
Meng Liu, Zhi-Yu Nie, Ren-Ren Li, Wei Zhang, Hui Wang, Yu-Sheng He, Li-Juan Zhao, Yun-Xia Li
BACKGROUND This study aimed to investigate the correlation of brain perfusion with white matter hyperintensity (WMH), brain atrophy, and cognition in patients with moderate to severe posterior cerebral artery stenosis (PCAS). MATERIAL AND METHODS 65 patients with memory decline as the main complaint and no history of brain infarction were recruited from the Department of Neurology of Tongji Hospital. Patients with moderate to severe PCAS were included in case group, and subjects with normal intracranial blood vessels served as controls...
August 17, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Muhammad Farhan Khaliq, Maria Shoaib, Syed Maaz Tariq, Muhammad Taimoor Khan
Cerebral air embolism (CAE) is a rare, avoidable and potentially fatal iatrogenic complication. Here, we report a case of CAE associated with a central venous catheter in the internal jugular vein that resulted in neurological deficits and generalised epileptic seizures. A 64-year-old man admitted for fasciotomy for compartment syndrome developed CAE with left-sided neurological deficits. The suspected origin was retrograde air flow from the right internal jugular venous catheter. The air spontaneously resorbed without the need for specific therapy, and he made a good recovery...
August 16, 2018: BMJ Case Reports
Jonathan J Stone, Jennifer M Boland, Robert J Spinner
INTRODUCTION: Using proper surgical technique, schwannomas can be resected safely, with a low recurrence rate and high likelihood of improvement in symptomatology. There are multiple peritumoral tissue layers and finding the correct plane is critical to safe tumor enucleation. The contents of the pseudocapsule tissue surrounding a schwannoma are not well described and the consequences of resecting or leaving pseudocapsule are unknown. METHODS: An institutional database was searched for any pathology reports that contained both of the words "schwannoma" and "capsule"...
August 13, 2018: World Neurosurgery
Shan Deng, Yonglan He, Na Chen, Lan Zhu
OBJECTIVE: To analyze the spectrum of Type I and Type II malformations in Chinese patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. METHODS: It was a cross-sectional descriptive study that used data from a National Clinical Research Center for Obstetrical and Gynecological Diseases of China, reviewed from January 2009 to July 2017. Patients with MRKH syndrome, both in- and out-patients were reviewed and analyzed. RESULTS: A total of 274 cases were included in the analysis: 197 (71...
August 13, 2018: Journal of Pediatric and Adolescent Gynecology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"