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Neurological cases

Francesc Malagelada, Miki Dalmau-Pastor, Cyrus Sahirad, Maria Cristina Manzanares-Céspedes, Jordi Vega
INTRODUCTION: Operative correction of symptomatic bunionette by means of minimally invasive (MI) osteotomies of the 5th metatarsal (M5) has gained popularity. This study aims to investigate the safe zones of commonly used techniques and the risk of injury to neurological structures. MATERIALS AND METHODS: Ten human fresh frozen cadaveric feet were dissected and branches of the sural nerve were identified. A frontal section of the feet was performed at the site of the skin incision described for M5 MI osteotomies (corresponding to distal and mid diaphyseal osteotomies)...
March 1, 2018: Foot
Ashley N Selner, Clayton L Rosinski, Ryan G Chiu, David Rosenberg, Anisse N Chaker, Hamidou Drammeh, Darian R Esfahani, Ankit I Mehta
BACKGROUND: Epilepsy is one of the most common neurologic disorders, and often remains refractory despite pharmacologic treatment. In patients unamenable to surgical resection of seizure foci, vagal nerve stimulation (VNS) may provide benefit. Multiple case series have attempted to construct a risk profile for VNS, yet are largely confined to pediatric or single-center populations. OBJECTIVE: To compile a risk profile for adults undergoing VNS, utilizing multi-center patient data from an international database...
October 13, 2018: World Neurosurgery
Ryosuke Matsuda, Kentaro Tamura, Fumihiko Nishimura, Ichiro Nakagawa, Yasushi Motoyama
BACKGROUND: To avoid permanent neurologic deficits and preserve brain function in and near the eloquent area, intraoperative electrical stimulation mapping (IESM) is necessary. However, little is known about how these subcortical regions are involved in calculation processing function in patients with glioma. CASE DESCRIPTION: We report the case of a 56-year-old right-handed woman working at a primary school as a teacher who had recurrent left parietal glioma. She underwent initial surgical resection for a low-grade glioma present in the left parietal lobe 14 months prior to recurrence...
October 13, 2018: World Neurosurgery
João Luiz Gomes Carneiro Monteiro, José Alcides Almeida de Arruda, Amanda Regina Silva de Melo, Ricardo Jorge Vasconcelos Barbosa, Suzana Célia de Aguiar Soares Carneiro, Belmiro Cavalcante do Egito Vasconcelos
PURPOSE: Traumatic dislocation of the mandibular condyle into the middle cranial fossa (DMCCF) is a rare event after maxillofacial trauma. Treatment may be performed with closed or open reduction (with or without craniotomy), and arthroplasty procedures might be necessary for long-standing cases. The aims of this study were to perform an integrative review of traumatic DMCCF cases reported in an electronic database and to report a case in which cerebrospinal fluid leakage occurred after open treatment...
September 20, 2018: Journal of Oral and Maxillofacial Surgery
David H Ge, Nicholas D Stekas, Christopher G Varlotta, Charla R Fischer, Anthony Petrizzo, Themistocles S Protopsaltis, Peter G Passias, Thomas J Errico, Aaron J Buckland
STUDY DESIGN: Retrospective cohort study at a single institution. OBJECTIVE: To analyze the perioperative and postoperative outcomes of patients who underwent open transforaminal lumbar interbody fusion (O-TLIF) and bilateral minimally invasive (MIS) Wiltse approach TLIF (Wil-TLIF). SUMMARY OF BACKGROUND DATA: Several studies have compared Open TLIF to MIS TLIF, however, comparing the techniques using a large cohort of one-level TLIFs has not been fully explored...
October 15, 2018: Spine
Ying Kan, Yu Wang, Wei Wang, Jie Liu, Jigang Yang
Diffuse large B-cell lymphoma (DLBCL) was the most frequent subtype of lymphoid malignancy. Corpus callosum involvement of DLBCL was rarely reported. We present a case of DLBCL involving not only lymph nodes and bowels but also corpus callosum, detected by FDG PET/CT in a patient without neurological symptoms. After 4 cycles of systemic and intrathecal chemotherapy, all previously visualized abnormal activity disappeared on the follow-up FDG PET/CT.
October 15, 2018: Clinical Nuclear Medicine
Stela Petrova Dikova, Stefan Atanasov Dragoev, Violeta Silvi Chernodrinska
INTRODUCTION: The purpose of this study was to establish the prevalence of amblyopia in children, aged 4 to 10 years, in Bulgaria, who underwent a complete eye examination. METHODS: The study was designed as cross-sectional epidemiological study, and the results were calculated in percentages. A complete ophthalmological examination was performed on 1,675 children, aged 4 to 10 years (mean age 7.7 years), during the period 01 Feb 2017-21 April 2017, in five cities, in the western part of Bulgaria...
October 16, 2018: Strabismus
J Holton, M Jones, Z Klezl, M Czyz, M Grainger, P Rehousek
We present the case of a 75-year-old man with a rapidly progressive cervical myelopathy on a background of a 3-year history of neck pain and a severely degenerative cervical spine. The patient developed progressive myelopathy over a six-month period and suffered from worsening kyphosis. Suspicion of an underlying oncological process prompted transfer to our tertiary referral unit. Biopsy was consistent for Paget's disease, an extremely rare diagnosis of the cervical spine. Magnetic resonance imaging revealed cord compression between C4 and C6 with associated cord signal change indicative of myelopathy...
October 16, 2018: Annals of the Royal College of Surgeons of England
Werner Keenswijk, Ann Raes, Marieke de Clerck, Johan Vande Walle
Shigatoxin-associated hemolytic uremic syndrome (STEC-HUS) is associated with significant mortality and morbidity. Case fatalities are often associated with severe neurological involvement in children and advanced age in adults but specific treatment is currently unavailable. Plasma exchange (PE) could theoretically enable removal of Shigatoxins, pro-inflammatory cytokines and prothrombotic factors and has been used in deteriorating patients with STEC-HUS but the efficacy remains uncertain. In order to assess efficacy of PE in STEC-HUS a literature review was performed...
October 15, 2018: Therapeutic Apheresis and Dialysis
Gouthami Nalakonda, Mimsa Islam, Vera E Chukwu, Ahmad Soliman, Rujina Munim, Inas Abukraa
The main purpose of this paper is to bring together all the antibodies and markers related to neurological and psychiatric manifestations in systemic lupus erythematosus and also the pharmacology that could help treat these symptoms. Existing research data regarding specific antibodies involved in the disease process and drugs that were being studied was collected and analyzed. After reviewing the studies published by various authors, symptoms were shown to be mainly caused by antibodies against N-methyl-D-aspartate receptor (NMDAR) antibodies, anti-endothelial, anti-ribosomal P, antiphospholipid antibodies, cytokines like interferons and chemokines...
August 3, 2018: Curēus
Ichiro Okano, Yuki Midorikawa, Natsuki Midorikawa, Yushi Hoshino, Takatoshi Sawada, Tomoaki Toyone, Katsunori Inagaki
Study design: Single-center, retrospective case-control study. Objectives: This study aimed to determine the risk factors for progression of neurological symptoms after anterior fusion for cervical spine trauma with no or incomplete spinal cord injury. Setting: Community-based hospital with an acute care center in Japan. Methods: We retrospectively reviewed 54 consecutive unstable subaxial cervical spine fracture/dislocation cases that had undergone surgical treatment...
2018: Spinal Cord Series and Cases
Abdulrahman Hamad Al-Abdulwahhab, Abdulaziz Mohammad Al-Sharydah, Sari Saleh Al-Suhibani, Saeed Ahmad Al-Jubran, Ali Khalaf Al-Haidey, Abdulkhaliq Ibrahim Al-Hifzi, Wissam Al-Issawi
Background: Spinal myelitis is an infrequent manifestation of spinal cord infection. It is caused by the Schistosoma species, which are endemic in South America, part of the Middle East, and Africa. Case presentation: We report the case of a 13-year-old male adolescent complaining of progressive lower back pain and weakness of the lower extremities for 3 days. Initial magnetic resonance imaging revealed typical transverse myelitis. Subsequently, parasite serology showed a markedly elevated level of Schistosoma antibody titers, and cerebrospinal fluid analysis yielded normal results...
2018: Patient Safety in Surgery
Si-Yu Lin, Shi-Zhong Zhang, Jian-Xiong An, Xiao-Yan Qian, Xin-You Gao, Yong Wang, Wen-Xing Zhao, Derek Eastwood, Doris K Cope, John P Williams
Objective: This study was to evaluate the effectiveness of ultrasound-guided percutaneous ozone injections around the cervical dorsal root ganglions of zoster-associated pain (ZAP) patients. Study design: Retrospective comparative study. Settings: The study was conducted at a pain center of a university hospital. Patients and methods: From June 2016 to July 2017, a total number of 30 patients with ZAP were treated with ultrasound-guided percutaneous ozone injection around the cervical dorsal root ganglion (DRG) at the injured nerve level (C2-C8)...
2018: Journal of Pain Research
Abdelrahim A Sadek, Mohammed H Hassan, Nesreen A Mohammed
Background: Phenylketonuria (PKU) is considered to be a rare inborn error of metabolism but one of the commonest causes of mental retardation if untreated. Objectives: The present study was done to characterize the clinical patterns of PKU and analyze various neuropsychiatric outcomes in PKU children in Sohag Province, Egypt. Patients and methods: A prospective cohort study was conducted on 113 PKU patients, diagnosed during the period from 2012 to 2017, at the Pediatric Neurology Clinic of Sohag University Hospital, Upper Egypt...
2018: Neuropsychiatric Disease and Treatment
Elizabeth Kouzmitcheva, Pradeep Krishnan, Nomazulu Dlamini, Gabrielle deVeber, Daune L MacGregor, Mahendranath Moharir
No abstract text is available yet for this article.
October 16, 2018: Neurology
Victoria A Chang, Dawn M Meyer, Brett C Meyer
BACKGROUND: Acute stroke codes may be activated for anisocoria, but how often these codes lead to a final stroke diagnosis or alteplase treatment is unknown. The purpose of this study was to assess the frequency of anisocoria in stroke codes that ultimately resulted in alteplase administration. METHODS: We retrospectively assessed consecutive alteplase-treated patients from a prospectively-collected stroke registry between February 2015 and July 2018. Based on the stroke code exam, patients were categorized as having isolated anisocoria [A+(only)], anisocoria with other findings [A+(other)], or no anisocoria [A-]...
October 13, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Takaki Shimizu, Hideki Murakami, Apiruk Sangsin, Satoru Demura, Satoshi Kato, Kazuya Shinmura, Noriaki Yokogawa, Norihiro Oku, Ryo Kitagawa, Hiroyuki Tsuchiya
BACKGROUND: Spinal metastases of gastrointestinal stromal tumors are rare; however, the incidence has been increasing since the introduction of tyrosine kinase inhibitors, which have improved overall survival. Due to the rarity of cases, there are no treatment guidelines for spinal metastases of gastrointestinal stromal tumors. We describe a patient who underwent spinal metastasectomy for a rectal gastrointestinal stromal tumor; we further provide a review of all cases of gastrointestinal stromal tumors with spinal metastases...
October 16, 2018: Journal of Medical Case Reports
Néstor F Sandoval, Catalina Vargas Acevedo, Juan Bernardo Umaña, Ivonne Pineda, Albert Guerrero, Carlos Obando, Juan P Umaña, Jaime Camacho
BACKGROUND: The approach to coarctation of the aorta with hypoplastic aortic arch is controversial. We evaluated the outcomes in patients with coarctation of the aorta with or without hypoplastic aortic arch operated through a posterior left lateral thoracotomy. METHODS: A retrospective cohort of patients with aortic coarctation, who underwent repair between January 2009 and October 2017, was analyzed. Preoperative, postoperative, and echocardiographic characteristics were reviewed...
November 2018: World Journal for Pediatric & Congenital Heart Surgery
Ashok Pedabelle Reddy, Rajat Mahajan, Tarush Rustagi, Harvinder Singh Chhabra
Study Design: Retrospective case series. Purpose: Cauda equina syndrome (CES) is associated with etiologies such as lumbar disc herniation (LDH) and lumbar canal stenosis (LCS). CES has a prevalence of 2% among patients with LDH and exhibits variable outcomes, even with early surgery. Few studies have explored the factors influencing the prognosis in terms of bladder function. Therefore, we aimed to assess the factors contributing to bladder recovery and propose a simplified bladder recovery classification...
October 16, 2018: Asian Spine Journal
Roberto Roncon-Albuquerque, Sérgio Gaião, Paulo Figueiredo, Nuno Príncipe, Carla Basílio, Paulo Mergulhão, Sofia Silva, Teresa Honrado, Francisco Cruz, Manuel Pestana, Gerardo Oliveira, Luis Meira, Ana França, João Paulo Almeida-Sousa, Fernando Araújo, José-Artur Paiva
AIM: To assess the feasibility of an integrated program of extracorporeal cardiopulmonary resuscitation (ECPR) and uncontrolled donation after circulatory determination of death (uDCDD) in refractory cardiac arrest (rCA). METHODS: Single center, prospective, observational study of selected patients with in-hospital (IHCA) and out-of-hospital (OHCA) rCA occurring in an urban area of ~1.5 million inhabitants, between October-2016 and May-2018. 65 year old or younger patients without significant bleeding or comorbidities with witnessed nonasystolic cardiac arrests were triaged to ECPR if they had a reversible cause and high quality CPR lasting < 60 min...
October 12, 2018: Resuscitation
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