Mouhanad Babi, Roberto Riesco, Louisa Boyer, Ayodele Fatona, Angelo Accardo, Laurent Malaquin, Jose Moran-Mirabal
In nature, cells exist in three-dimensional (3D) microenvironments with topography, stiffness, surface chemistry, and biological factors that strongly dictate their phenotype and behavior. The cellular microenvironment is an organized structure or scaffold that, together with the cells that live within it, make up living tissue. To mimic these systems and understand how the different properties of a scaffold, such as adhesion, proliferation, or function, influence cell behavior, we need to be able to fabricate cellular microenvironments with tunable properties...
December 20, 2021: ACS Applied Bio Materials