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https://www.readbyqxmd.com/read/29492930/autoimmune-gastritis-assessment-of-olga-and-olgim-staging-systems
#1
Sana Ben Slama, Dorra Ben Ghachem, Amen Dhaoui, Sarra Ben Rejeb, Mohamed Taieb Jomni, Mohamed Hédi Dougui, Khadija Bellil
BACKGROUND: Autoimmune gastritis present a risk of cancer related to atrophy and intestinal metaplasia. Two recent classifications OLGA (Operative Link on Gastritis Assessment) and OLGIM (Operative Link on Gastritic Intestinal Metaplasia assessment) have been proposed to reveal the high progressive risk forms (stages III and IV). AIM: To evaluate the OLGA and OLGIM staging systems in chronic autoimmune gastritis. METHODS: A descriptive single institution study of 30 cases of autoimmune gastritis...
April 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/28946145/impact-of-cyclooxygenase-2-1195-g-carrier-genotype-associated-with-intestinal-metaplasia-and-endoscopic-findings-based-on-kyoto-classification
#2
Yasuhiro Kodaka, Seiji Futagami, Atsushi Tatsuguchi, Hiroshi Yamawaki, Hitomi Sato, Satomi Hashimoto, Tetsuro Kawagoe, Nobue Ueki, Hiroyuki Nagoya, Yuuta Maruki, Kazumasa Miyake, Katya Gudis, Choitsu Sakamoto, Katsuhiko Iwakiri
BACKGROUND/AIMS: We aimed to clarify whether cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES-1) genotypes were associated with certain histological findings and endoscopical appearances based on Kyoto classification. METHODS: We enrolled 285 Helicobacter pylori-infected gastritis patients. Genotypes of COX-2 1195, COX-2 1290, mPGES-1, interleukin-1β (IL-1β) 511 and tumour necrosis factor-α (TNF-α) 308 were analyzed. Genotyping was performed by polymerase chain reaction...
2017: Digestion
https://www.readbyqxmd.com/read/27897066/single-gastric-biopsy-in-subjects-with-low-acid-secretion-after-maximal-histamine-stimulation
#3
Poul M Christiansen, Å Johansen
Examinations of 83 patients and 13 healthy subjects with the augmented histamine test and gastric biopsy show that a maximal acid secretion lower than 10 mEq HCl/hour signifies a diffuse gastritic lesion, the type of which can be verified by a single gastric biopsy. Detailed investigations of the nature and clinical course of gastritis, however, require repeated tests of gastric function and multiple gastric biopsies.
April 1966: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27759774/relationship-between-the-presence-of-helicobacter-pylori-with-inflammatory-endoscopic-changes-in-gastroduodenal-mucosa
#4
COMPARATIVE STUDY
Irma Cláudia Saboya Ribeiro, Luiz Fernandao Kubrusly, Paulo Afonso Nunes Nassif, Patrícia Fernanda Saboya Ribeiro, Rodrigo de Oliveira Veras, Aline Neppel
Background: The influence of Helicobacter pylori (HP) in inflammatory disorders of the digestive mucosa has been the subject of several studies since socioeconomic, personal and environmental factors were implicated in the bacteria transmission. Aim: To correlate the inflammatory endoscopic findings with HP infection and the onset of mucosal diseases mucous of the upper digestive tract. Method: Comparative observational study, in which were collected data from 2247 patients who underwent upper endoscopy and biopsies for HP with urease test...
July 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27683773/gastric-and-jejunal-histopathological-changes-in-patients-undergoing-bariatric-surgery
#5
Rosemary Simões Nomelini Rodrigues, Élia Cláudia de Souza Almeida, Silvia Maria Perrone Camilo, Júverson Alves Terra-Júnior, Lucinda Calheiros Guimarães, Ana Cristina da Rocha Duque, Renata Margarida Etchebehere
Background: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. Aim: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. Methods: This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative. Results: In the preoperative group, 80...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27679942/influence-of-duodenogastric-reflux-in-the-gastric-mucosa-histological-changes-of-rats-infected-with-helicobacter-pylori
#6
José Carlos Ribeiro DE Araujo, Jorge José DE Carvalho, Humberto Oliveira Serra
OBJECTIVE: to evaluate the influence of Duodenal reflux in histological changes of the gastric mucosa of rats infected with Helicobacter pylori submitted to pyloroplasty. METHODS: after two weeks of acclimation, we infected 30 male Wistar rats with Helicobacter pylori. We randomly divided them into three groups: one submitted to pyloroplasty, another to partial gastrectomy and the third, only infected, was not operated. After six months of surgery, euthanasia was carried out...
July 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/27546737/irisolidone-attenuates-ethanol-induced-gastric-injury-in-mice-by-inhibiting-the-infiltration-of-neutrophils
#7
Geum-Dan Kang, Sang-Yoon Lee, Se-Eun Jang, Myung Joo Han, Dong-Hyun Kim
SCOPE: This study was designed to determine whether irisolidone and its glycoside kakkalide, which are the major constituents of the flower of Pueraria lobata (Kudzu) can attenuate ethanol-induced gastritic injury in mice. METHODS AND RESULTS: Irisolidone and kakkalide inhibited IL-8 secretion and NF-κB activation in lipopolysaccharide-stimulated KATO III cells. Therefore, we investigated their protective effects against ethanol-induced gastric injury in mice. Pretreatment with kakkalide or irisolidone decreased the area of hemorrhagic ulcerative lesions caused by ethanol and suppressed stomach myeloperoxidase activity, CXCL4 secretion, and NF-κB activation...
February 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27438029/conventional-videoendoscopy-can-identify-helicobacter-pylori-gastritis
#8
Alexandre Gomes, Thelma Larocca Skare, Manoel Alberto Prestes, Maiza da Silva Costa, Roberta Dombroski Petisco, Gabriela Piovezani Ramos
BACKGROUND: Studies with latest technologies such as endoscopy with magnification and chromoendoscopy showed that various endoscopic aspects are clearly related to infection by Helicobacter pylori (HP). The description of different patterns of erythema in gastric body under magnification of images revived interest in identifying these patterns by standard endoscopy. AIM: To validate the morphologic features of gastric mucosa related to H. pylori infection gastritis allowing predictability of their diagnosis as well as proper targeting biopsies...
April 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27200133/-helicobacter-pylori-gastritis-assessment-of-olga-and-olgim-staging-systems
#9
Sana Ben Slama, Dorra Ben Ghachem, Amen Dhaoui, Mohamed Taieb Jomni, Mohamed Hédi Dougui, Khadija Bellil
Helicobacter pylori (H pylori) gastritis presents a risk of cancer related to atrophy and intestinal metaplasia. Two recent classifications OLGA (Operative Link on Gastritis Assessment) and OLGIM (Operative Link on Gastritic Intestinal Metaplasia assessment) have been proposed to identify high-risk forms (stages III and IV). The aim of this study is to evaluate the OLGA and OLGIM staging systems in H pylori gastritis. A descriptive study of 100 cases of chronic H pylori gastritis was performed. The revaluation of Sydney System parameters of atrophy and intestinal metaplasia, of gastric antrum and corpus, allowed identifying respectively the stages of OLGA and OLGIM systems...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/24866386/syk-src-targeted-anti-inflammatory-activity-of-codariocalyx-motorius-ethanolic-extract
#10
Eunji Kim, Kee Dong Yoon, Woo-Shin Lee, Woo Seok Yang, Shi Hyoung Kim, Nak Yoon Sung, Kwang-Soo Baek, Yong Kim, Khin Myo Htwe, Young-Dong Kim, Sungyoul Hong, Jong-Hoon Kim, Jae Youl Cho
ETHNOPHARMACOLOGICAL RELEVANCE: Codariocalyx motorius (Houtt.) H. Ohashi (Fabaceae) is one of several ethnopharmacologically valuable South Asian species prescribed as an herbal medicine for various inflammatory diseases. Due to the lack of systematic studies on this plant, we aimed to explore the inhibitory activity of Codariocalyx motorius toward inflammatory responses using its ethanolic extract (Cm-EE). MATERIALS AND METHODS: Lipopolysaccharide (LPS)-treated macrophages and a HCl/EtOH-induced gastritis model were used for evaluation of the anti-inflammatory activity of Cm-EE...
August 8, 2014: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/24803922/gene-polymorphism-of-interleukin-1-and-8-in-chronic-gastritis-patients-infected-with-helicobacter-pylori
#11
Agostinho Caleman Neto, Lucas T Rasmussen, Roger W de Labio, Valdeir F de Queiroz, Marília de Ac Smith, Gustavo A Viani, Spencer Lm Payão
BACKGROUND: Epidemiological investigations have indicated that Helicobacter pylori induces inflammation in the gastric mucosa regulated by several interleukins. The genes IL1B and IL8 are suggested as key factors in determining the risk of gastritis. The aim of this paper was to evaluate the association of gene polymorphism of interleukin-1 and interleukin-8 with chronic gastrits in H. pylori infected patients. A total of 60 patients underwent endoscopic procedure. Biopsy samples were collected for urease test, histopathological and molecular exams...
2014: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/23140055/-clinical-observation-on-therapeutic-effects-of-mild-moxibustion-in-superficial-gastritis-patients-with-spleen-stomach-deficiency-cold-pattern
#12
Hua Xie, Mi Liu, Xiao-Rong Chang, Jie Yan, Zhan Yi, Shou-Xiang Yi, Zeng-Hui Yue, Ya-Ping Lin, Jiong Song
OBJECTIVE: To observe the curative effect of different duration of mild moxibustion in superficial gastritis patients with deficiency cold pattern of spleen and stomach. METHODS: A total of 84 superficial gastritis patients were randomly divided into moxibustion-20 min group, moxibustion-40 min group and medication (Ranitidine) group, with 28 cases in each group. Mild moxibustion was applied to bilateral Zusanli (ST 36) and Zhongwan (CV 12, odd days), Pishu (BL 20) and Weishu (BL 21, even-numbered days) for 20 min and 40 min respectively, once daily for 20 days...
August 2012: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/22777705/both-ifn-%C3%AE-and-il-17-are-required-for-the-development-of-severe-autoimmune-gastritis
#13
Eric Tu, Desmond K Y Ang, Shayne A Bellingham, Thea V Hogan, Michele W L Teng, Mark J Smyth, Andrew F Hill, Ian R van Driel
IL-17, produced by a distinct lineage of CD4(+) helper T (Th) cells termed Th17 cells, induces the production of pro-inflammatory cytokines from resident cells and it has been demonstrated that over-expression of IL-17 plays a crucial role in the onset of several auto-immune diseases. Here we examined the role of IL-17 in the pathogenesis of autoimmune gastritis, a disease that was previously believed to be mediated by IFN-γ. Significantly higher levels of IL-17 and IFN-γ were found in the stomachs and stomach-draining lymph nodes of mice with severe autoimmune gastritis...
October 2012: European Journal of Immunology
https://www.readbyqxmd.com/read/21608221/-effect-of-huazhuo-jiedu-recipe-on-gastric-juice-compositions-and-tumor-markers-in-patients-with-chronic-atrophic-gastritic-precancerosis
#14
RANDOMIZED CONTROLLED TRIAL
Dian-gui Li, Yan-ru Du, Min Guo
OBJECTIVE: To observe clinical efficacy of Huazhuo Jiedu Recipe (HJR) on chronic atrophic gastritic precancerosis (CAGP), and its effect on contents of lactic acid, total acid, free acid, and nitrite in the gastric juice, as well as tumor markers in gastric juice and blood. METHODS: Two hundred and twenty-nine patients with CAGP were randomly assigned to two groups, the 119 patients in the treated group orally took HJR and the 110 patients in the control group orally took Weifuchun Tablet...
April 2011: Chinese Journal of Integrated Traditional and Western Medicine
https://www.readbyqxmd.com/read/20499452/-morpho-immunological-criteria-for-diagnosis-of-gastritis-associated-with-helicobacter-pylori
#15
T D Kanareĭtseva, S P Chernutskaia, V B Gervaziev, G V Sukhareva
31 bioptates in the antral mucosa of 24 patients with a chronic gastritis and a body of a stomach for revealing H. pylori were being analysed and for the further studying morpho-immunology communications. The presence of H. pylori in bioptates, gastrits's activity (leukocytic infiltration), gastrits's degree evidence, also eosinophilus's presence and IgE containing plasmocytus had correlated with antibodies titre to H. pylori. After inspection, at the majority of patients serum antibodies to H. pylori correlated with positive respiratory-test...
2010: Experimental & Clinical Gastroenterology
https://www.readbyqxmd.com/read/20118544/effects-of-artichoke-leaf-extract-on-acute-gastric-mucosal-injury-in-rats
#16
COMPARATIVE STUDY
Kazuo Ishida, Ryoji Kojima, Makoto Tsuboi, Yuka Tsuda, Mikio Ito
The present study was designed to clarify the effects of an ethanol extract of artichoke leaf on acute gastric mucosal injury in rats. Oral administration of artichoke leaf extract dose-dependently prevented absolute ethanol-induced (125-500 mg/kg) or restraint plus water immersion stress-induced gastric mucosal injury (1000-2000 mg/kg). The artichoke leaf extract contains 1% cynaropicrin and 0.8% chlorogenic acid as main components and 70% dextrin as a vehicle. Cynaropicrin at doses of 1/100 of artichoke leaf extract [ethanol-induced mucosal injury: 5 mg/kg, per os (p...
2010: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/19514353/-association-of-the-morphological-features-of-gastric-parietal-cells-with-the-concentration-of-h-k-atpase-autoantibodies-in-chronic-gastrititis
#17
S V Azanchevskaia, V F Ivanova, V P Novikova, N M Anichkov, P V Antonov
Chronic gastritis was morphologically verified in 119 patients. The count of parietal cells per 100 epitheliocytes of fundic glands was estimated. The sizes of parietal cells were measured by the morphometric computer program Videotest. For the diagnosis of autoimmune chronic gastritis (ACG), the level of antibodies to H+K+ATPase of gastric parietal cells in the patients' serum was determined by enzyme immunoassay. Childhood ACG has been found to be characterized by hyperplasia and structural changes of parietal cells with their preserved total count...
January 2009: Arkhiv Patologii
https://www.readbyqxmd.com/read/17724739/augmented-gp130-mediated-cytokine-signalling-accompanies-human-gastric-cancer-progression
#18
C B Jackson, L M Judd, T R Menheniott, I Kronborg, C Dow, N D Yeomans, A Boussioutas, L Robb, A S Giraud
H. pylori infection accounts for most cases of gastric cancer, but the initiating events remain unclear. The principal H. pylori pathogenicity-associated CagA protein disrupts intracellular SHP-2 signalling pathways including those used by the IL-6 family cytokines, IL-6 and IL-11. Imbalanced IL-6 family cytokine signalling in the gp130(757FF) mouse model of gastric cancer arising from hyperactivation of oncogenic STAT3 after altered SHP-2 : ERK1/2 signalling produces dysplastic antral tumours preceded by gastritis and metaplasia...
October 2007: Journal of Pathology
https://www.readbyqxmd.com/read/17489359/effects-of-constituents-of-amomum-xanthioides-on-gastritis-in-rats-and-on-growth-of-gastric-cancer-cells
#19
Yong Soo Lee, Min Hee Kang, So Yean Cho, Choon Sik Jeong
In this study we investigated the effects of constituents of Amomum xanthioides (AX) on gastritis in rats and on the growth of human gastric cancer cells. The ethanol extract of Amomum xanthioides significantly inhibited HCl ethanol-induced gastric lesions and the growth of Helicobacter pylori (H. pylon). The ethanol extract of AX was further fractionated with hexane, chloroform, butanol and H20. Among these fractions, oral treatment with the butanol fraction at a dose of 350 mg/kg was the most effective at preventing HCl* ethanol-induced gastric lesions...
April 2007: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/16398701/gastritis-in-neonatal-balb-ccrslc-mice-induced-by-immunization-without-adjuvant-can-be-transferred-to-syngeneic-nu-nu-recipients
#20
D L V Greenwood, J W Sentry
The popularly exploited murine neonatal thymectomy experimental autoimmune gastritis (nTx:EAG) model requires the animal to be in a state of lymphopenia. Here we report on a novel murine immunization (without adjuvant) model that can establish a lasting gastritis. We demonstrate that the immunization model (imm:EAG) results in a bona fide autoimmune disease and define the resulting pathology and serology observed and compare it with that reported for human autoimmune gastritis. Immune cells present in the stomachs of imm:EAG gastritic mice include CD8 T cells, CD11b and Gr1 (granulocytes/monocytes) and B cells...
January 2006: Scandinavian Journal of Immunology
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