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Visceral adiposity index

Michelle M Harbin, Neil E Hultgren, Aaron S Kelly, Donald R Dengel, Nicholas G Evanoff, Justin R Ryder
Background: The relationship of pediatric severe obesity (SO) and central aortic blood pressure (BP) has yet to be established. Methods: We conducted a cross-sectional study of 348 youth (48.5% male, 12.7±0.1 years) with a wide range of body mass index (BMI) values: normal weight (NW; 5th and <85th BMI percentile); overweight/obesity (OW/OB; 85th to <120% of the 95th BMI percentile); and SO (≥120% of the 95th BMI percentile). Measures of central aortic blood pressure were obtained via applanation tonometry with SphygmoCor MM3 software...
August 9, 2018: American Journal of Hypertension
Suzanne Vogelezang, Susana Santos, Eline M van der Beek, Marieke Abrahamse-Berkeveld, Liesbeth Duijts, Aad van der Lugt, Janine F Felix, Vincent W V Jaddoe
Background: Although a longer duration of breastfeeding has been associated with a lower risk of childhood obesity, the impact on specific organ fat depots is largely unknown. Objective: We examined the associations of any breastfeeding, duration and exclusiveness of breastfeeding, and of age at introduction of solid foods with measures of general, visceral, and organ adiposity at 10 y. Design: In a population-based prospective cohort study in 4444 children, we obtained information on infant feeding by questionnaires...
August 11, 2018: American Journal of Clinical Nutrition
Farhad Ahmadi-Kani Golzar, Rozita Fathi, Soleiman Mahjoub
There is little understanding about dietary proteins and their potential contribution to obesity-induced inflammation. This study investigates the effect of 10 weeks of aerobic training and whey protein (WP) supplementation on visceral adipose tissue inflammation in rats fed a high fat diet (HFD). In the first phase, 40 male Wistar rats were randomly divided into two groups: 1- normal diet (n=8), 2- high-fat diet (n=32). After this period-which lasted nine weeks-in the second phase, rats fed a HFD were randomly assigned into four groups: (n=8/group): 1- sedentary, 2- WP, 3- aerobic training, and 4- WP + aerobic training...
August 14, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Takamasa Kobayashi, Hirokazu Kawai, Oki Nakano, Satoshi Abe, Hiroteru Kamimura, Akira Sakamaki, Kenya Kamimura, Atsunori Tsuchiya, Masaaki Takamura, Satoshi Yamagiwa, Shuji Terai
Background: Prognosis of patients with hepatocellular carcinoma (HCC) who undergo transcatheter intra-arterial therapies, including transcatheter arterial chemoembolization and transcatheter arterial infusion chemotherapy, is affected by many clinical factors including liver function and tumor progression. However, the effect of body composition such as skeletal muscle and visceral and subcutaneous adipose tissues (VAT and SAT, respectively) on the prognosis of these patients remains unclear...
2018: Cancer Management and Research
Chaonan Xu, Zhimin Ma, Yunfeng Wang, Xiangtong Liu, Lixin Tao, Deqiang Zheng, Xiuhua Guo, Xinghua Yang
BACKGROUND & AIMS: Although evidence indicates that visceral adipose tissue is associated with non-alcoholic fatty liver disease (NAFLD), it is unclear whether the visceral adiposity index (VAI) can predict the incidence of NAFLD. This study aimed to determine if the VAI is an independent risk factor of NAFLD and if there is a dose-response relationship. METHODS: We explored the relationship between VAI levels and NAFLD in a health check-up cohort established in 2012...
August 12, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
S Katherine Sweatt, Barbara A Gower, Angela Y Chieh, Yang Liu, Li Li
OBJECTIVES: Sleep duration is associated with adiposity in adults. Abdominal adiposity specifically is strongly correlated with metabolic alterations, however, the relationships between abdominal adiposity and sleep quality are incompletely understood. The purpose of this study is to test the hypothesis that abdominal adiposity is related to poor sleep quality while total adiposity is not; and to explore whether pathways, including immune system and hypothalamic-pituitary-adrenal axis, link abdominal adiposity to poor sleep quality...
July 25, 2018: Psychoneuroendocrinology
Valentina Guarnotta, Giulia Di Bella, Giuseppe Pillitteri, Alessandro Ciresi, Carla Giordano
Background: Cardiovascular disease is a frequent complication of type 1 diabetes (T1D). We evaluated the effectiveness of switching from glargine to degludec in reducing the cardiovascular risk factors, the Framingham risk score (FRS) and visceral adiposity index (VAI) in patients with T1D and autoimmune polyglandular syndrome (APS). Methods: We selected 66 T1D outpatients who had been on stable treatment with glargine for at least 5 years. Among them, 30 patients maintained glargine (group A), while 36 were switched to degludec (group B) for 12 months...
2018: Frontiers in Endocrinology
Debarchan Jena, Arun Kumar Choudhury, Swayamsidha Mangaraj, Mamata Singh, Binoy Kumar Mohanty, Anoj Kumar Baliarsinha
Aim of the Study: This study aimed to compare the different adiposity parameters, namely visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) between patients with polycystic ovary syndrome (PCOS) and controls. In addition, it aimed to correlate these adiposity indices with hormonal parameters as well as cardiovascular (CV) risk factors in patients with PCOS. Materials and Methods: Newly diagnosed PCOS patients of reproductive age group according to Rotterdam criteria were included...
May 2018: Indian Journal of Endocrinology and Metabolism
Vincenzo Serretta, Alberto Abrate, Simone Siracusano, Cristina Scalici Gesolfo, Marco Vella, Fabrizio Di Maida, Antonina Cangemi, Giuseppe Cicero, Elisabetta Barresi, Chiara Sanfilippo
Context: The correlation between aggressive prostate cancer and obesity mainly based on body mass index (BMI) and pathology after surgery remains controversial. Aims: The aim of the study was to correlate BMI, visceral adiposity index (VAI), and the plasmatic levels of leptin, adiponectin, and matrix metalloproteinase-3 (MMP-3), and biomarkers of adipose tissue function, with the detection of Gleason patterns 4 and 5 at biopsy. Subjects and Methods: Consecutive patients with prostate cancer at 12-core transrectal biopsy were enrolled...
July 2018: Urology Annals
Mathijs Drummen, Elke Dorenbos, Anita Ce Vreugdenhil, Anne Raben, Mikael Fogelholm, Margriet S Westerterp-Plantenga, Tanja Adam
AIMS: To assess the effects of a weight maintenance period comprising two diets differing in protein intake, after weight loss, on intrahepatic lipid content and implications for insulin sensitivity. MATERIALS AND METHODS: A total of 25 participants (BMI: 31.1±3.5 kg/m2; intrahepatic lipid (IHL): 8.7±8.3%; fasting glucose: 6.4±0.6 mmol/l; HOMA-IR: 3.7±1.6; Matsuda index: 3.4±2.9) started an 8-week low energy diet followed by a 2-year weight maintenance period with either high protein (HP) or medium protein (MP) dietary guidelines...
August 7, 2018: American Journal of Physiology. Endocrinology and Metabolism
Zhiguang Ping, Xiaoting Pei, Peige Xia, Yuansi Chen, Rui Guo, Chenxi Hu, Mustapha Umar Imam, Yanzi Chen, Panpan Sun, Li Liu
AIM: To seek anthropometric indices that estimate visceral and subcutaneous adipose tissue (VAT and SAT) by meta-analysis and comparing the predictive efficacy based on different characteristics of participants. METHODS: PubMed, PubMed Central, Web of Science, China National Knowledge Infrastructure and Wanfang databases were searched for publications containing correlation coefficients of VAT and/or SAT with waist circumference (WC) and/or body mass index (BMI)...
August 4, 2018: Diabetes Research and Clinical Practice
J W Lee, S M Lee, Y A Chung
AIM: To investigate the prognostic significance of computed tomography (CT) attenuation and 2-[18 F]-fluoro-2-deoxy-d-glucose (FDG) uptake in subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) for predicting overall survival (OS) in patients with pancreatic adenocarcinoma. MATERIALS AND METHODS: Data were collected retrospectively from 66 patients with pancreatic adenocarcinoma who had undergone pretreatment combined FDG positron-emission tomography (PET)/CT imaging and subsequent curative or palliative treatment...
August 1, 2018: Clinical Radiology
Jadwiga Hamułka, Magdalena Górnicka, Agnieszka Sulich, Joanna Frąckiewicz
BACKGROUND & AIMS: Studies on changes in plasma α-tocopherol levels during body fat reduction in obese persons are not clear. The aim of the present study was to assess factors associated with α-tocopherol status in obese people and to examine changes in α-tocopherol status after a 6-week AntioxObesity weight loss program. METHODS: The study was conducted in 60 overweight or obese adults, aged 18-54 years old. Food intake data were collected using the 3-day record method and a semi-quantitative food-frequency questionnaire...
July 20, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Anne E Bantle, Tyler A Bosch, Donald R Dengel, Qi Wang, Douglas G Mashek, Lisa S Chow
Obesity is a well-established risk factor for insulin resistance and type 2 diabetes mellitus, and body fat distribution has important implications for this metabolic risk. In this cross-sectional study, we used dual X-ray absorptiometry body composition data from 123 young adult participants with overweight or obesity, and correlated with 2 indices of insulin resistance calculated from oral glucose tolerance tests. Participants were 70% women, with mean (standard error) age 30.1 (0.6) yr, body mass index (BMI) 34...
June 7, 2018: Journal of Clinical Densitometry
Tadeusz Dereziński, Dorota Zozulińska-Ziółkiewicz, Aleksandra Uruska, Mariusz Dąbrowski
BACKGROUND: The visceral adiposity index (VAI) is considered to be a reliable indicator of adipose tissue dysfunction and cardiometabolic disease risk. The aim of this study was to evaluate its usefulness in assessing cardiometabolic risk in a sample of elderly women living in a rural-urban community in central Poland. METHODS: A total of 365 women aged 65 to 74 years were included in this cross-sectional study. All patients were interviewed to obtain their history of diabetes mellitus, myocardial infarction, stroke, and revascularization...
July 31, 2018: Diabetes/metabolism Research and Reviews
Ilse M Schrover, Yolanda van der Graaf, Wilko Spiering, Frank Lj Visseren
Introduction We evaluated the relationship between adipokine plasma concentrations and body fat distribution and the metabolic syndrome. Methods In a cohort of 1215 patients with clinically manifest vascular disease the relation between subcutaneous adipose tissue, visceral adipose tissue, waist circumference, body mass index and plasma concentrations of adipsin, chemerin, monocyte chemoattractant protein-1, migration inhibitory factor, nerve growth factor, resistin, plasma amyloid A1, adiponectin, leptin, plasminogen activator inhibitor-1 and hepatic growth factor were cross-sectionally assessed with linear regression and adjusted for age and gender...
July 27, 2018: European Journal of Preventive Cardiology
Lei Zhao, Danielle L Harrop, Arnold C T Ng, William Y S Wang
BACKGROUND: Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot. Although EAT volume is associated with the incidence and burden of atrial fibrillation (AF), its role in subclinical left atrial (LA) dysfunction is unclear. This study aims to evaluate the relationships between EAT volumes, LA function, and LA global longitudinal strain. METHODS: One hundred and thirty people without obstructive coronary artery disease or AF were prospectively recruited into the study in Australia and underwent cardiac computed tomography and echocardiography...
August 2018: Canadian Journal of Cardiology
Hon-Cheong So, Kwan-Long Chau, Fu-Kiu Ao, Cheuk-Hei Mo, Pak-Chung Sham
BACKGROUND: Cardiovascular diseases represent a major health issue in patients with schizophrenia (SCZ) and bipolar disorder (BD), but the exact nature of cardiometabolic (CM) abnormalities involved and the underlying mechanisms remain unclear. Psychiatric medications are known risk factors, but it is unclear whether there is a connection between the disorders (SCZ/BD) themselves and CM abnormalities. METHODS: Using polygenic risk scores and linkage disequilibrium score regression, we investigated the shared genetic bases of SCZ and BD with 28 CM traits...
July 26, 2018: Psychological Medicine
Ming-Feng Xia, Huan-Dong Lin, Ling-Yan Chen, Li Wu, Hui Ma, Qian Li, Qiqige Aleteng, Ying Chen, Yi-Xuan Sun, Yu Hu, Bai-Shen Pan, Xiao-Ying Li, Xin Gao
OBJECTIVE: A Chinese visceral adiposity index (CVAI) was recently established to estimate the visceral fat area in Chinese adults. This study aimed to investigate the risk of incident prediabetes and diabetes in relation to visceral adiposity calculated by CVAI. METHODS: A total of 2558 subjects with normal plasma glucose levels from the Shanghai Changfeng Study were enrolled in a prospective cohort study. The independent associations of basal visceral fat area by CVAI and its longitudinal change with incident prediabetes and diabetes were identified using Cox regression analyses...
July 23, 2018: Diabetes/metabolism Research and Reviews
Tavga Ahmed Aziz, Saad Abdulrahman Hussain, Taha Othman Mahwi, Zheen Aorahman Ahmed
Background and aim: Ginkgo biloba (GKB) extract has shown to be beneficial in experimental models of metabolic and inflammatory disorders such as diabetes and metabolic syndrome (MTS). The objective of this pilot clinical study was to evaluate the effects of GKB extract as an "add-on" treatment with metformin (Met) in MTS patients. Patients and methods: We performed a randomized, placebo-controlled, double-blinded clinical study in subjects with MTS. Forty patients completed the 90-day clinical trial and were randomly allocated to administer either GKB extract (120 mg capsule/day) or placebo (120 mg starch/day) as an add-on treatment with their currently used doses of Met for 90 days...
2018: Therapeutics and Clinical Risk Management
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