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Visceral adiposity index

Kaitlin Day, Alastair Kwok, Alison Evans, Fernanda Mata, Antonio Verdejo-Garcia, Kathryn Hart, Leigh C Ward, Helen Truby
This study aimed to compare the use of the bioelectrical impedance device (BIA) seca® mBCA 515 using dual X-ray absorptiometry (DXA) as a reference method, for body composition assessment in adults across the spectrum of body mass indices. It explores the utility of simple anthropometric measures (the waist height ratio (WHtR) and waist circumference (WC)) for the assessment of obesity. In the morning after an overnight fast (10 h), 30 participants underwent a body composition DXA (GE iDXA) scan, BIA (seca 515), and anthropometric measures...
October 10, 2018: Nutrients
Rosaley D Prakaschandra, Datshana P Naidoo
Background: We sought to determine the association of echocardiographically derived epicardial adipose tissue (EAT) thickness, which is a component of visceral adipose tissue, with the metabolic syndrome (MetS) in a cohort of randomly selected community participants. Methods: South African-Asian Indians aged 15-64 years were recruited over a 2-year period after informed consent was obtained. All participants who had complete measurements done for biochemistry and echocardiography (using established criteria), were dichotomized into the MetS or non-MetS groups defined according to the harmonized criteria...
July 2018: Journal of Cardiovascular Echography
Gokce Anik Ilhan, Begum Yildizhan, Tanju Pekin
This study was performed to assess the impact of lipid accumulation product (LAP) and visceral adiposity index (VAI) on clinical, hormonal, and metabolic parameters in lean women with PCOS. Retrospective analysis of 120 consecutive lean PCOS subjects was performed. Subjects were divided into two groups according to HOMA-IR, as IR + and IR-. A HOMA-IR value above 2.5 was used to indicate IR. Clinical, hormonal and metabolic parameters were compared between the two groups. Correlations between LAP and VAI and clinical, hormonal, metabolic features in women PCOS were analyzed...
October 10, 2018: Gynecological Endocrinology
You Cheol Hwang, Wilfred Y Fujimoto, Steven E Kahn, Donna L Leonetti, Edward J Boyko
BACKGROUND: Recent studies have suggested that high density lipoprotein (HDL) cholesterol is inversely associated with the development of hypertension. We aimed to determine the association between different HDL cholesterol subclasses and risk of future hypertension. METHODS: A total of 270 Japanese Americans (130 men, 140 women) without hypertension between the ages of 34 to 75 years were enrolled. Blood pressure was measured with a mercury sphygmomanometer, and average blood pressure was calculated...
September 28, 2018: Diabetes & Metabolism Journal
Donghee Kim, Won Kim, Sae Kyung Joo, Jung Ho Kim, Stephen A Harrison, Zobair M Younossi, Aijaz Ahmed
AIMS: We compared (1) demographic and clinical characteristics, and (2) determinants of nonalcoholic steatohepatitis (NASH) and significant fibrosis in non-obese and obese NAFLD. METHODS: A cross-sectional study of 664 Asian subjects (mean age 53.1 years; men 50.3%) with biopsy-proven NAFLD and controls was conducted. Subjects were divided by their body mass index (BMI) into obese (BMI ≥25 kg/m2 ) and non-obese (BMI <25 kg/m2 ). RESULTS: Observations in subjects with non-obese NAFLD were in between non-obese controls and obese NAFLD subjects for BMI, sagittal abdominal diameter (SAD), aminotransferase levels, insulin resistance, and abdominal visceral adipose tissue (VAT) area...
October 8, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
Lance E Davidson, Steven C Hunt, Ted D Adams
Obesity and low cardiorespiratory fitness are both established predictors of cardiovascular disease morbidity and mortality. Whether the protective effects of fitness outweigh the deleterious effects of obesity, however, remains a topic of debate. To extend knowledge of the relative influence of fitness and fatness on cardiovascular disease outcomes, however, attention must be paid to measurement quality. Eliminating inherent bias of self-report and including the highest quality assessments of cardiorespiratory fitness and fatness simultaneously are imperative for head-to-head comparisons...
October 8, 2018: European Journal of Clinical Nutrition
Shuaibing Wang, Rui Peng, Shuying Liang, Kaiyan Dong, Wei Nie, Qian Yang, Nan Ma, Jianying Zhang, Kaijuan Wang, Chunhua Song
BACKGROUND: To compare the efficiency of bioelectrical indices (visceral fat index, VFI; percentage body fat, PBF) and anthropometric indices (body mass index, BMI; waist circumference, WC; waist-to-height ratio, WHtR; a body shape index, ABSI) in the relation to prehypertension (120-139/80-89mmHg) among Chinese population. METHODS: Using stratified multistage random sampling method, a general population-based sample of 11,175 adults in Henan province were selected during 2013 to 2015...
October 3, 2018: Clinical Cardiology
Sigrid A Dekker, Raymond Noordam, Nienke R Biermasz, Albert de Roos, Hildo J Lamb, Frits R Rosendaal, Patrick C N Rensen, Diana van Heemst, Renée de Mutsert
OBJECTIVE: This study aimed to investigate the associations of sleep duration and sleep quality with visceral adipose tissue (VAT) in middle-aged individuals. METHODS: In this cross-sectional analysis of baseline measurements of the Netherlands Epidemiology of Obesity (NEO) study, participants underwent anthropometry and completed the Pittsburgh Sleep Quality Index (PSQI) for assessing short sleep duration (as sex-specific age-adjusted percentiles) and poor quality (PSQI > 5)...
October 2018: Obesity
You-Bin Lee, Kyung Mook Choi
Vascular inflammation plays a central role in atherosclerosis, from initiation and progression to acute thrombotic complications. Modified low-density lipoproteins (LDLs) and apoB-containing particles stimulate plaque inflammation by interacting with macrophages. Loss of function of high-density lipoprotein (HDL) for preventing LDL particles from oxidative modification in dyslipidemic states may amplify modified LDL actions, accelerating plaque inflammation. Diets are one of the most important factors that can affect these processes of lipoprotein oxidation and vascular inflammation...
September 28, 2018: Nutrients
Daniel T Cervone, Justin Sheremeta, Emily N Kraft, David J Dyck
Ghrelin has garnered interest as a gut-derived regulator of lipid metabolism, beyond its classical roles in driving appetite and growth hormone release. Ghrelin's circulating concentrations follow an ultradian rhythm, peak immediately before a meal and point towards a potential metabolic role in reducing the mobilization of fatty acid stores in preparation for the storage of ingested food. Here, we demonstrate that both acylated and unacylated ghrelin have physiological roles in attenuating lipolysis in mature subcutaneous and visceral adipose tissue depots of rats...
September 28, 2018: Adipocyte
Anna Pedret, Rosa M Valls, Lorena Calderón-Pérez, Elisabet Llauradó, Judit Companys, Laura Pla-Pagà, Ana Moragas, Francisco Martín-Luján, Yolanda Ortega, Montse Giralt, Antoni Caimari, Empar Chenoll, Salvador Genovés, Patricia Martorell, Francisco M Codoñer, Daniel Ramón, Lluís Arola, Rosa Solà
BACKGROUND: The effects of probiotic Bifidobacterium animalis subsp. lactis CECT 8145 (Ba8145) and those of its heat-killed form (h-k Ba8145) on human anthropometric adiposity biomarkers are unknown. OBJECTIVE: To assess the effect of Ba8145 and h-k Ba8145 ingestion on anthropometric adiposity biomarkers. DESIGN: Randomized, parallel, double-blind, placebo-controlled trial with abdominally obese individuals. Participants (n = 135) consumed 1 capsule/day containing 1010 colony forming unit (CFU) of Ba8145, 1010 CFU of h-k Ba8145, or placebo (maltodextrin) for 3 months...
September 27, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Raffael Ott, Kerstin Melchior, Jens H Stupin, Thomas Ziska, Karen Schellong, Wolfgang Henrich, Rebecca C Rancourt, Andreas Plagemann
Context: Altered expression of the insulin receptor (IR) in adipose tissue (AT) could causally contribute to the etiophathogenesis of gestational diabetes mellitus (GDM). Transcriptional regulation via epigenetic mechanisms, e.g. DNA methylation, may play a critical role. However, the human IR promoter DNA methylation patterns and involvement in gene expression are unknown. Objective: We evaluated IR mRNA and protein expression accompanied by targeted DNA methylation analyses in AT and blood cells of women with GDM and their offspring...
September 26, 2018: Journal of Clinical Endocrinology and Metabolism
Claire Thiberge, Cloé Charpentier, André Gillibert, Romain Modzelewski, Jean-Nicolas Dacher, Guillaume Savoye, Céline Savoye-Collet
Background and Aims: Changes in body composition have been described in patients with Crohn's disease, but their predictive performances on disease evolution remain undefined. The aims of our study were to assess, in patients with Crohn's disease requiring abdominal computed tomography, body composition by computed tomography, and to study the outcome according to various body composition parameters at the time of the computed tomography. Methods: Patients with Crohn's disease who underwent abdominal computed tomography for suspected complications were retrospectively included...
September 27, 2018: Journal of Crohn's & Colitis
Yu Chung Chooi, Cherlyn Ding, Faidon Magkos
Obesity is a complex multifactorial disease. The worldwide prevalence of overweight and obesity has doubled since 1980 to an extent that nearly a third of the world's population is now classified as overweight or obese. Obesity rates have increased in all ages and both sexes irrespective of geographical locality, ethnicity or socioeconomic status, although the prevalence of obesity is generally greater in older persons and women. This trend was similar across regions and countries, although absolute prevalence rates of overweight and obesity varied widely...
September 22, 2018: Metabolism: Clinical and Experimental
Evangeline Vassilatou, Sophia Lafoyianni, Dimitra Argyro Vassiliadi, Dimitrios Ioannidis, Stavroula A Paschou, Maria Mizamtsidi, Maria Panagou, Andromachi Vryonidou
OBJECTIVE: Visceral adiposity index (VAI), initially developed for the assessment of cardiometabolic risk, has been also proposed for the detection of nonalcoholic fatty liver disease (NAFLD); however, its diagnostic performance for NAFLD is still under investigation. We evaluated VAI as a marker of NAFLD and compared its diagnostic performance with that of three other NAFLD indices - fatty liver index (FLI), lipid accumulation product (LAP) and hepatic steatosis index (HSI) - in premenopausal women with and without polycystic ovary syndrome (PCOS) assessed for NAFLD by ultrasonography...
October 2018: Maturitas
Theodora Sideratou, Fiona Atkinson, Grace J Campbell, Peter Petocz, Kim S Bell-Anderson, Jennie Brand-Miller
Maternal diet and gestational hyperglycaemia have implications for offspring health. Leptin ( LEP ) and fat mass and obesity-associated ( FTO ) alleles are known to influence body fat mass in humans, potentially via effects on appetite. We hypothesized that expression of Fto , Lep , and other appetite-related genes ( Argp, Npy, Pomc, Cart, Lepr ) in the offspring of female mice are influenced by the glycaemic index (GI) of carbohydrates in the maternal diet. C57BL/6 mice were randomly assigned to low or high GI diets and mated with chow-fed males at eight weeks of age...
September 20, 2018: Nutrients
Pandora L Wander, Tomoshige Hayashi, Kyoko Kogawa Sato, Shinichiro Uehara, Yonezo Hikita, Donna L Leonetti, Steven E Kahn, Wilfred Y Fujimoto, Edward J Boyko
AIMS: Visceral adiposity measured by computed tomography (CT) as intra-abdominal fat area (IAFA) predicts metabolic diseases. Existing adiposity surrogates have not been systematically compared to a regression-based model derived in individuals of Japanese ancestry. We developed and validated a method to estimate IAFA in individuals of Japanese ancestry and compared it to existing adiposity surrogates. METHODS: We assessed age, BMI, waist circumference (WC), fasting lipids, glucose, smoking status, grip strength, mid-thigh circumference (MTC), humeral length, leg length, and IAFA by single-slice CT at the umbilicus for 622 Japanese Americans...
November 2018: Journal of Diabetes and its Complications
Susana Santos, Claire Monnereau, Janine F Felix, Liesbeth Duijts, Romy Gaillard, Vincent W V Jaddoe
BACKGROUND/OBJECTIVES: Maternal obesity and excessive gestational weight gain are associated with an increased risk of obesity in offspring. It remains unclear whether maternal adiposity also affects organ fat, which has important adverse cardiometabolic health consequences and whether the associations reflect intrauterine causal mechanisms. We examined the associations of parental pre-pregnancy body mass index (BMI) and gestational weight gain with general, abdominal, pericardial, and liver fat in 10-year-old children...
September 19, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Lan Wang, Jeremiah Perez, Nancy Heard-Costa, Audrey Y Chu, Roby Joehanes, Peter J Munson, Daniel Levy, Caroline S Fox, L Adrienne Cupples, Ching-Ti Liu
OBJECTIVE: Indices of body fat distribution are heritable, but few genetic signals have been reported from genome-wide association studies (GWAS) of computed tomography (CT) imaging measurements of body fat distribution. We aimed to identify genes associated with adiposity traits and the key drivers that are central to adipose regulatory networks. SUBJECTS: We analyzed gene transcript expression data in blood from participants in the Framingham Heart Study, a large community-based cohort (n up to 4303), as well as implemented an integrative analysis of these data and existing biological information...
September 19, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Geraldine J Ooi, Paul R Burton, Jacqueline Bayliss, Arthe Raajendiran, Arul Earnest, Cheryl Laurie, William W Kemp, Catriona A McLean, Stuart K Roberts, Matthew J Watt, Wendy A Brown
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), driven by the obesity epidemic, has become the most common form of liver disease. Despite this, there is controversy regarding the prevalence and severity of NAFLD in obesity. Obesity-related factors, such as increasing adiposity, metabolic disease and inflammation, may influence prevalence. We therefore prospectively measured NAFLD prevalence in obesity and studied factors associated with NAFLD. MATERIALS AND METHODS: We recruited consecutive bariatric patients...
September 18, 2018: Obesity Surgery
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