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Periodontal disease interventions

Davidson Fróis Madureira, Izabella Lucas De Abreu Lima, Giselle Cabral Costa, Elizabeth Maria Bastos Lages, Carolina Castro Martins, Tarcília Aparecida Da Silva
OBJECTIVES: The aim of this systematic review was to evaluate human gingival crevicular fluid (GCF) tumor necrosis factor-alpha (TNF-α) as a potential biomarker for diagnosis of periodontal disease (International prospective register of systematic reviews [PROSPERO] number: CRD42015020199). METHODS: An electronic search for TNF-α in human GCF was conducted until May 17, 2018. Data from systemically healthy patients with healthy periodontium or periodontal disease were incorporated...
December 2018: Journal of Evidence-based Dental Practice
Hee-Jung Lim, AeJung Im, Han-A Cho
INTRODUCTION: Individuals with visual impairment cannot recognize early-stage oral diseases, thus fail to receive prompt treatment. AIMS: To evaluate the association between visual impairment and dental care utilization in patients aged ≥65 years. DESIGN: Retrospective analysis. MATERIALS AND METHODS: We analyzed annual pooled data collected by the Korean Health Panel between 2011 and 2014; a total of 1472 patients and 13,285 dental visits were analyzed...
November 12, 2018: Archives of Gerontology and Geriatrics
Eun S Park, Hyeon W Yim, Kang S Lee
Dental anxiety causes patients to refuse or delay treatment, which may exacerbate oral diseases. The aim of the current randomized controlled trial was to determine whether progressive muscle relaxation therapy could relieve dental anxiety. The trial included 68 periodontal patients with dental anxiety scores of ≥13 who were randomly assigned to either an intervention group or a control group (n = 34 per group). The intervention group was administered progressive muscle relaxation therapy for 20 min and oral health education for 15 min before periodontal treatment once per week for 4 wk...
November 14, 2018: European Journal of Oral Sciences
Michael Raedel, Heinz-Werner Priess, Steffen Bohm, Barbara Noack, Yvonne Wagner, Michael H Walter
OBJECTIVES: The aim of this study was to evaluate tooth loss after periodontal treatment. METHODS: The data was collected from the digital database of a major German national health insurance company. Periodontal treatment was the intervention in the treatment group. Kaplan-Meier survival analyses on the patient level with the primary outcome extraction were carried out over four years. A control group without treatment was matched and analysed. Differences were tested with the Log-Rank-test...
November 6, 2018: Journal of Dentistry
Kuo-Ting Sun, Shih-Chueh Chen, Cheng-Li Lin, Jui-Ting Hsu, I-An Chen, I-Ting Wu, Kalaiselvi Palanisamy, Te-Chun Shen, Chi-Yuan Li
BACKGROUND/PURPOSE: Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease affecting oral health. Evidence shows possible association between T1DM and periodontal diseases (PDs). We conducted a nationwide population-based study in Taiwan, with a 14-year follow-up to investigate the risk of PDs in T1DM patients. METHODS: We used data from the National Health Insurance Research Database in Taiwan. The T1DM cohort was identified with newly diagnosed T1DM from 1998 to 2011...
October 31, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Uislen B Cadore, Marília B L Reis, Sergio H L Martins, Marcos de M Invernici, Arthur B Novaes, Mario Taba, Daniela B Palioto, Michel R Messora, Sergio L S Souza
BACKGROUND: This double-blind, randomized, controlled clinical trial assessed the efficacy of multiple sessions of antimicrobial photodynamic therapy (aPDT) as an adjunct to surgical periodontal treatment (ST) in patients with severe chronic periodontitis (SCP). METHODS: Sixteen patients with SCP were treated with aPDT+ST (test group, TG) or ST only (control group, CG), in a split-mouth design. aPDT was applied at 0, 2, 7, and 14 postoperative days only in TG. All patients were followed up for 90 days after surgery...
November 1, 2018: Journal of Periodontology
Mohammad Sultan Alakhali, Sadeq Ali Al-Maweri, Hashem Motahir Al-Shamiri, Khaled Al-Haddad, Esam Halboub
OBJECTIVES: Many animal and human studies have shown associations between periodontitis and non-alcoholic fatty liver disease (NAFLD). Hence, the present systematic review sought to investigate such a potential association. METHODS: PubMed/Medline, Scopus, Embase, and Web of Science databases were thoroughly searched to identify all relevant studies. The eligibility criteria were all observational (cross-sectional studies, case-control, cohort studies, and case reports) and interventional studies that assessed the relationship between periodontitis and NAFLD in humans...
December 2018: Clinical Oral Investigations
Audrey Peteuil, Corinne Rat, Sahar Moussa-Badran, Maud Carpentier, Jean-François Pelletier, Frederic Denis
Objective: The aim of this study was to test the feasibility of a therapeutic educational program in oral health (TEPOH) for persons with schizophrenia (PWS). Design: In a qualitative study, we explored the representation of oral health before and after a TEPOH. Clinical Setting : PWS are at greater risk of decayed and missing teeth and periodontal diseases. In a previous publication, we described the different steps in building a TEPOH by taking into account the experiences of PWS concerning oral health quality of life...
2018: International Journal of Dentistry
Małgorzata Woźniewicz, Paulina M Nowaczyk, Anna Kurhańska-Flisykowska, Marzena Wyganowska-Świątkowska, Małgorzata Lasik-Kurdyś, Jarosław Walkowiak, Joanna Bajerska
Periodontal disease is highly prevalent worldwide, and consumption of certain foods, such as fruits, seem to improve the effectiveness of periodontal therapy (PT) due to their antiadhesive, immunomodulatory, and antioxidative properties. We hypothesized that the cranberry functional beverage (CFB) consumed for eight weeks improves gingival inflammation indices via inhibition of dental plaque, and alterations in antioxidant status, and systemic inflammation in patients with gingivitis. In this two-arm randomized controlled study, fifty participants were divided into an experimental group (CFB), administered daily with 750 ml CFB, or a control group administered the same amount of water...
October 2018: Nutrition Research
Hadi Bazyar, Hassan Gholinezhad, Leila Moradi, Parvin Salehi, Faezeh Abadi, Maryam Ravanbakhsh, Ahmad Zare Javid
BACKGROUND: Diabetes mellitus (DM) and periodontitis are two common chronic diseases with bidirectional relationship. Oxidative stress plays a key role in the pathogenesis of these two diseases. The aim of this study was to investigate the effects of melatonin supplementation in adjunct with non-surgical periodontal therapy on periodontal status, serum melatonin and inflammatory markers in type 2 DM patients with chronic periodontitis (CP). MATERIALS AND METHODS: In this double-blind clinical trial study, 50 type 2 DM patients with CP were randomly allocated to the intervention and control groups...
October 16, 2018: Inflammopharmacology
Mattias Pettersson, Jean Pettersson, Anders Johansson, Margareta Molin Thorén
OBJECTIVES: The aim of this study was to investigate the titanium (Ti) content of biopsies from patients with severe peri-implantitis or controls without Ti exposure. BACKGROUND: Peri-implantitis is considered to be an infectious disease, but recent studies have shown that Ti can aggravate inflammation in combination with bacterial products. The Ti content of peri-implantitis and periodontitis (controls) tissue is unknown. METHODS: Thirteen patients referred for peri-implantitis and eleven for periodontitis treatment were included in the study...
October 16, 2018: Journal of Oral Rehabilitation
Masaya Akashi, Nagisa Nanba, Junya Kusumoto, Takahide Komori
In brief, perioperative oral intervention consists of elimination of odontogenic foci and maintenance of oral hygiene in patients undergoing surgery. The importance of oral intervention before, during, and after medical treatments is well-known, especially in cancer patients, because odontogenic foci such as untreated deep dental caries or periodontitis can cause systemic infection in patients with myelosuppression resulting from chemotherapy. Although perioperative oral intervention is currently recommended for patients with cardiovascular disease, its efficacy in this population has not been established...
October 5, 2018: General Thoracic and Cardiovascular Surgery
Rui Ma, Fardad Moein Vaziri, Gregory J Sabino, Nima D Sarmast, Steven M Zove, Vincent J Iacono, Julio A Carrion
Background : Glycogen storage diseases (GSDs) are genetic disorders that result from defects in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types. It also manifests with impaired neutrophil chemotaxis and neutropenic episodes which results in severe destruction of the supporting dental tissues, namely the periodontium. Although GSD Type Ib cannot be cured, associated symptoms and debilitating oral manifestations of the disease can be managed through collaborative medical and dental care where early detection and intervention is of key importance...
October 3, 2018: Dentistry journal
Jadwiga Jośko-Ochojska, Katarzyna Rygiel, Lidia Postek-Stefańska
Epigenetics is the study of inheritable changes in gene expression without changes in the underlying deoxyribonucleic acid (DNA) sequence. The main mechanisms of epigenetic regulation include DNA methylation, modifications in histones, and micro-ribonucleic acids (miRNA). Recent research evidence has shown that environmental and lifestyle factors dynamically interact with the genome, influencing epigenetic changes, from development to the later stages of life. This happens across a spectrum, from physiological to pathological conditions, such as genetic defects, developmental disorders, infectious or inflammatory processes, cancers, mental disorders, and substance abuse...
October 2, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Neel Shimpi, Ingrid Glurich, Dixie Schroeder, Callahan Katrak, Po-Huang Chyou, Amit Acharya
This cross-sectional study sought to assess the current awareness, knowledge, and behavior regarding diabetes mellitus (DM) and periodontal disease (PD) association among a convenience sample of patients from a large Wisconsin-based integrated medical-dental health care organization serving largely rurally based communities. An anonymous 10-question survey was distributed at regional medical and dental centers of dental and medical clinics of a single health care institution over a 4-week period, to achieve a cross-sectional sampling of patients aged 18 to 80 years...
September 21, 2018: Health Promotion Practice
R Ananthalakshmi, Jaideep Mahendra, P Jayamathi, Little Mahendra, Nashra Kareem, S Subramaniam
Background: Yogic stretching (asana) has been proven to have an effect on salivary human beta-defensin-2 (HBD-2) concentration, which is an antimicrobial peptide and is an inflammatory marker in periodontal disease. Sudarshan Kriya Pranayama (SKP) is a part of yoga which involves rhythmic breathing. Hence, we aim to evaluate the periodontal parameters and to estimate the salivary HBD-2 level before and after SKP program in periodontitis individuals. Materials and Methods: An interventional study was designed and individuals were divided into three groups: Group I - healthy periodontium, Group II - chronic gingivitis, and Group III - chronic periodontitis...
September 2018: Dental Research Journal
Jake E Thistle, Baiyu Yang, Jessica L Petrick, Jin-Hu Fan, You-Lin Qiao, Christian C Abnet, Philip R Taylor, Katherine A McGlynn
BACKGROUND: Tooth loss has been reported to be associated with the risk of liver cancer in several prior studies in economically advantaged countries. Whether this relationship is also evident in economically disadvantaged populations is not known. METHODS: We analyzed data from the Nutrition Intervention Trials, two randomized placebo-controlled trials of vitamin/mineral supplementation in Linxian, China. Participants who reported having lost permanent teeth were examined to determine the number of teeth remaining...
2018: PloS One
Ellie T Knight, W Murray Thomson
In this paper, we consider personalized periodontics from a public health perspective. Periodontitis is an under-acknowledged and important public health problem, and there has long been interest in identifying and treating those who are at high risk of developing this disease. Although susceptibility/risk-assessment tools in periodontology are currently in their early stages of development, personalized periodontics is increasingly becoming a realistic approach. At the population level, however, personalized periodontics is not an effective way of improving periodontal health because it would target only those who seek help or are able to access care...
October 2018: Periodontology 2000
Jonathon T Newton, Koula Asimakopoulou
The oral health-related behavior of patients with periodontal disease is a critical determinant of their health. Psychological models of behavior provide a framework for the design of interventions to enhance oral health-related behavior. This article reviews published manuscripts on interventions to enhance oral health-related behavior, classifying the nature of the interventions according to current psychological models of behavior. Fifteen manuscripts reporting the findings of 14 studies were identified and reviewed...
October 2018: Periodontology 2000
Amarpreet Sabharwal, Isaac S Gomes-Filho, Elizabeth Stellrecht, Frank A Scannapieco
The goal of this review is to summarize the results of randomized trials reported since 2010 that assessed the effect of periodontal interventions on at least one systemic outcome in human subjects of any age, gender or ethnicity. Oral outcome measures included gingivitis, pocket depth, clinical attachment loss and/or radiographic bone loss and oral hygiene indices. Studies were excluded if the trial was not completed or if treatment was not randomized. The results suggest that nonsurgical periodontal intervention provided to pregnant women is safe and improves periodontal status without preventing adverse pregnancy outcomes...
October 2018: Periodontology 2000
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