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Noemi Valenti, Antonio Di Monaco, Imma Romanazzi, Nicola Vitulano, Federica Troisi, Federico Quadrini, Massimo Grimaldi
BACKGROUND: There are some functional bradyarrhythmias that are caused by a dysregulation of the autonomic nervous system, for which a therapeutic strategy of cardioneuroablation (CNA) is conceivable. CASE SUMMARY: In this study, we report the case of a 19-year-old woman with a non-congenital third-degree atrioventricular block (AVB), symptomatic for lipothymia and dyspnea caused by mild exertion. She had a structurally normal heart and no other comorbidities. The atropine test and the exercise stress test documented a sinus tachycardia at 190 bpm with a 2:1 AVB, a narrow QRS, and an atrioventricular conduction of 1:1 until reaching a sinus rhythm rate of 90 bpm...
2024: Frontiers in Cardiovascular Medicine
#2
JOURNAL ARTICLE
M F Chen, J F Zhang, X L Ren, Y Liu, L Huang
This study investigated the characteristics and frequency of perioperative anaphylactic shock induced by cefuroxime, so as to provide a reference for the safe and rational use of cefuroxime in the perioperative period. Cases of perioperative anaphylactic shock caused by cefuroxime in our hospital from 2011 to 2021 were extracted from the Adverse Drug Reaction Monitoring System. Literature reporting adverse drug reactions (ADR) including cefuroxime-induced anaphylactic shock in perioperative settings was collected from the CNKI, VIP, Wanfang, PubMed, and Web of Science databases from their respective inception to May 2022...
April 1, 2024: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
#3
JOURNAL ARTICLE
Piotr Kulakowski, Jakub Baran, Agnieszka Sikorska, Tomasz Krynski, Michal Niedzwiedz, Malgorzata Soszynska, Roman Piotrowski
BACKGROUND: Cardioneuroablation (CNA) is a promising therapy for reflex asystolic syncope, however, convincing data on the mid-term safety and efficacy of this procedure are still lacking. OBJECTIVE: To assess mid-term safety, efficacy and patient's acceptance of CNA. METHODS: This prospective observational single-center study included 115 consecutive patients (mean 39±13 years, 58% females) treated between 2016 and 2022 who completed at least one-year follow-up...
November 28, 2023: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#4
JOURNAL ARTICLE
Jiaying Li, Qingyun Xu, Wen Guo, Yuangang Qiu, Jin Dai
Exercise-induced tachycardia-dependent atrioventricular block with a normal electrocardiogram at rest is rare. Herein, we present a case of a 65-year-old woman with exercise-related chest suppression and treadmill exercise test-induced second- and third-degree atrioventricular blocks with narrow QRS wave and normal resting electrocardiogram. High atrioventricular block leads to tissue and organ insufficiency, resulting in exercise intolerance, dyspnea, dizziness, and syncope. Ths diagnosis was exercise-induced high-degree atrioventricular block...
August 25, 2023: Alternative Therapies in Health and Medicine
#5
JOURNAL ARTICLE
K S Alimbayev, M A Aripov, B Abay, B A Ainabekova, A Yu Goncharov
Idiopathic premature ventricular complexes (PVCs) are usually benign and are often treated conservatively. Data regarding radiofrequency catheter ablation (RFA) of PVCs from the aortic sinus of Valsalva are spare. Furthermore, there are limited data regarding complications and their solutions during RFA of PVCs from the aortic sinus of Valsalva. Here we describe a clinical case of symptomatic PVCs in a 27yrold young woman with reduced exercise tolerance and dyspnea. The patient had taken anti-arrhythmic group Ic, II, and III drugs with no significant effect...
July 28, 2023: Kardiologiia
#6
Takamasa Hashizaki, Yukihide Nishimura, Tokio Kinoshita, Kohei Minami, Makoto Kawanishi, Yasunori Umemoto, Fumihiro Tajima
Although thrombocytopenia, anasarca, fever, reticulin fibrosis/renal failure, and organomegaly (TAFRO) syndrome was first reported in 2010, its pathogenesis and prognosis are still unknown. Moreover, reports on rehabilitation in patients with TAFRO are limited. In severe cases, dyspnea and muscle weakness could impede improvements in activities of daily living (ADL). However, reports on exercise intensity showed no worsening of TAFRO within the load of 11-13 on the Borg scale. Herein, we describe the rehabilitation and progress in a 61-year-old woman with TAFRO syndrome complicated by cerebral infarction from early onset to discharge...
2023: Frontiers in Neurology
#7
JOURNAL ARTICLE
Hilma Holm, Erna V Ivarsdottir, Thorhildur Olafsdottir, Rosa Thorolfsdottir, Elias Eythorsson, Kristjan Norland, Rosa Gisladottir, Gudrun Jonsdottir, Unnur Unnsteinsdottir, Kristin E Sveinsdottir, Benedikt A Jonsson, Margret Andresdottir, David O Arnar, Asgeir O Arnthorsson, Kolbrún Birgisdottir, Kristbjorg Bjarnadottir, Solveig Bjarnadottir, Gyda Bjornsdottir, Gudmundur Einarsson, Berglind Eiriksdottir, Elisabet Eir Gardarsdottir, Thorarinn Gislason, Magnus Gottfredsson, Steinunn Gudmundsdottir, Julius Gudmundsson, Kristbjorg Gunnarsdottir, Anna Helgadottir, Dadi Helgason, Ingibjorg Hinriksdottir, Ragnar F Ingvarsson, Sigga S Jonasdottir, Ingileif Jonsdottir, Tekla H Karlsdottir, Anna M Kristinsdottir, Sigurdur Yngvi Kristinsson, Steinunn Kristjansdottir, Thorvardur J Love, Dora Ludviksdottir, Gisli Masson, Gudmundur Norddahl, Thorunn Olafsdottir, Isleifur Olafsson, Thorunn Rafnar, Hrafnhildur L Runolfsdottir, Jona Saemundsdottir, Svanur Sigurbjornsson, Kristin Sigurdardottir, Engilbert Sigurdsson, Martin I Sigurdsson, Emil L Sigurdsson, Valgerdur Steinthorsdottir, Gardar Sveinbjornsson, Emil A Thorarensen, Bjarni Thorbjornsson, Brynja Thorsteinsdottir, Vinicius Tragante, Magnus O Ulfarsson, Hreinn Stefansson, Thorsteinn Gislason, Mar Kristjansson, Runolfur Palsson, Patrick Sulem, Unnur Thorsteinsdottir, Gudmundur Thorgeirsson, Daniel F Gudbjartsson, Kari Stefansson
BACKGROUND: Persistent symptoms are common after SARS-CoV-2 infection but correlation with objective measures is unclear. METHODS: We invited all 3098 adults who tested SARS-CoV-2 positive in Iceland before October 2020 to the deCODE Health Study. We compared multiple symptoms and physical measures between 1706 Icelanders with confirmed prior infection (cases) who participated, and 619 contemporary and 13,779 historical controls. Cases participated in the study 5-18 months after infection...
July 6, 2023: Commun Med (Lond)
#8
JOURNAL ARTICLE
Alejandra Meza Contreras, Darrell B Newman, Lucio Cappelloni, Alexander S Niven, Michael R Mueller, Ravindra Ganesh, Ray W Squires, Amanda R Bonikowske, Thomas G Allison
BACKGROUND: Dyspnea and fatigue are characteristics of long SARS-CoV-2 (COVID)-19. Cardiopulmonary exercise testing (CPET) can be used to better evaluate such patients. RESEARCH QUESTION: How significantly and by what mechanisms is exercise capacity impaired in patients with long COVID who are coming to a specialized clinic for evaluation? STUDY DESIGN AND METHODS: We performed a cohort study using the Mayo Clinic exercise testing database...
May 19, 2023: Progress in Cardiovascular Diseases
#9
JOURNAL ARTICLE
Gisele Mendes Brito, Danilo Marcelo Leite do Prado, Diego Augusto Rezende, Luciana Diniz Nagem Janot de Matos, Irineu Loturco, Marcelo Luiz Campos Vieira, Ana Lúcia de Sá Pinto, Rodrigo Otávio Bougleux Alô, Lorena Christine Araújo de Albuquerque, Flavia Riva Bianchini, Ana Jéssica Pinto, Hamilton Roschel, Ítalo Ribeiro Lemes, Bruno Gualano
INTRODUCTION: Cardiopulmonary exercise testing (CPET) may capture potential impacts of COVID-19 during exercise. We described CPET data on athletes and physically active individuals with or without cardiorespiratory persistent symptoms. METHODS: Participants' assessment included medical history and physical examination, cardiac troponin T, resting electrocardiogram, spirometry and CPET. Persistent symptoms were defined as fatigue, dyspnea, chest pain, dizziness, tachycardia, and exertional intolerance persisting >2 months after COVID-19 diagnosis...
2023: Frontiers in Medicine
#10
JOURNAL ARTICLE
Ralf Ewert, Mohamed A Elhadad, Dirk Habedank, Alexander Heine, Beate Stubbe
BACKGROUND: Primary muscular disorders (metabolic myopathies, including mitochondrial disorders) are a rare cause of dyspnea. We report a case of dyspnea caused by a mitochondrial disorder with a pattern of clinical findings that can be classified in the known pathologies of mitochondrial deletion syndrome. CASE PRESENTATION: The patient presented to us at 29 years of age, having had tachycardia, dyspnea, and functional impairment since childhood. She had been diagnosed with bronchial asthma and mild left ventricular hypertrophy and treated accordingly, but her symptoms had worsened...
March 29, 2023: BMC Pulmonary Medicine
#11
Bryam López, Milagros Batallanos
Coronary artery fistulas are abnormal connections between the coronary arteries with a heart chamber or any of the major blood vessels. Fistulous connections between systemic arteries and pulmonary vessels are even less frequent. We present a case of a 71-year-old man with symptoms of dyspnea, exercise intolerance, and ventricular arrhythmia who attended the emergency department. Coronary angiography revealed bilateral coronary fistulas drained into the pulmonary circulation. Computed tomography angiography revealed the presence of fistulas arising from the descending aorta, right internal mammary artery, and subclavian arteries, all these drained into the pulmonary circulation...
May 2023: Radiology Case Reports
#12
JOURNAL ARTICLE
Takakazu Oka
BACKGROUND: Some patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) complain of persistent fatigue, dyspnea, pain, and cognitive dysfunction. These symptoms are often described as "long COVID". Whether a patient with long COVID might develop myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is of interest, as is the treatment and management of ME/CFS in a post-COVID patient. Here I report a patient, who, after an infection with SARS-CoV-2, developed ME/CFS and recovered after treatment...
February 28, 2023: BioPsychoSocial Medicine
#13
Thomas Bonitz, Luke Scypinski, Justin Chin, Christine M Lomiguen
Hypertrophic obstructive cardiomyopathy (HOCM) is a cardiovascular disease that is widely recognized as an important cause of various cardiovascular pathologies. Passed through an autosomal dominant inheritance pattern, mutations can result in cardiac dysfunction that can manifest in dyspnea, exercise intolerance, and sudden death. Panic disorder can present similarly to HOCM; however, precautions and treatment differ significantly. Here, we present a case of a 56-year-old male with a history of panic disorder who presented to the emergency department with recurrent episodes of palpitations, lightheadedness, and dyspnea, and who was subsequently hospitalized due to new ventricular tachyarrhythmia and diagnosed with HOCM...
November 2022: Curēus
#14
JOURNAL ARTICLE
Ciro Indolfi, Francesco Barillà, Cristina Basso, Marco Matteo Ciccone, Antonio Curcio, Paola Gargiulo, Savina Nodari, Giuseppe Mercuro, Massimo Mancone, Saverio Muscoli, Roberto Pedrinelli, Aldostefano Porcari, Carmen Spaccarotella, Francesco Romeo, Gianfranco Sinagra, Pasquale Perrone Filardi
Although the clinical course of COVID-19 in its acute phase is now delineated, less known is its late phase characterized by a heterogeneous series of sequelae affecting various organs and systems, including the cardiovascular system, which continue after the acute episode or arise after their resolution. This syndrome, now referred with the new acronym "PASC" (post-acute sequelae of SARS-CoV-2 infection) has been formally recognized by various scientific societies and international organizations that have proposed various definitions...
July 2022: Giornale Italiano di Cardiologia
#15
JOURNAL ARTICLE
Mahavir Singh, Sathnur Pushpakumar, Nia Bard, Yuting Zheng, Rubens P Homme, Sri Prakash L Mokshagundam, Suresh C Tyagi
The ongoing pandemic (also known as coronavirus disease-19; COVID-19) by a constantly emerging viral agent commonly referred as the severe acute respiratory syndrome corona virus 2 or SARS-CoV-2 has revealed unique pathological findings from infected human beings, and the postmortem observations. The list of disease symptoms, and postmortem observations is too long to mention; however, SARS-CoV-2 has brought with it a whole new clinical syndrome in "long haulers" including dyspnea, chest pain, tachycardia, brain fog, exercise intolerance, and extreme fatigue...
June 22, 2022: Molecular and Cellular Biochemistry
#16
Taiji Inamori, Kazuhisa Kodama, Yudai Tamura, Hideharu Okamatsu, Yukiko Sashida, Yoko Horibata, Eiji Taguchi, Koichi Nakao, Tomohiro Sakamoto
Ivabradine increases stroke volume, but does not have a negative impact on blood pressure (BP). Thus, a patient with low BP can benefit from treatment with ivabradine. A 72-year-old Japanese woman with asthma and chronic bronchitis presented with dyspnea. Her heart rate (HR) was 126 beats per minute and an electrocardiogram showed sinus tachycardia. The chest X-ray showed cardiomegaly and pulmonary congestion. A transthoracic echocardiogram (TTE) showed reduced left ventricular ejection function (LVEF) and severe functional mitral regurgitation (MR)...
January 2022: Journal of Cardiology Cases
#17
REVIEW
Giandomenico Bisaccia, Fabrizio Ricci, Vittoria Recce, Antonio Serio, Giovanni Iannetti, Anwar A Chahal, Marcus Ståhlberg, Mohammed Yunus Khanji, Artur Fedorowski, Sabina Gallina
Post-acute sequelae of SARS-CoV-2 (PASC), or long COVID syndrome, is emerging as a major health issue in patients with previous SARS-CoV-2 infection. Symptoms commonly experienced by patients include fatigue, palpitations, chest pain, dyspnea, reduced exercise tolerance, and "brain fog". Additionally, symptoms of orthostatic intolerance and syncope suggest the involvement of the autonomic nervous system. Signs of cardiovascular autonomic dysfunction appear to be common in PASC and are similar to those observed in postural orthostatic tachycardia syndrome and inappropriate sinus tachycardia...
November 15, 2021: Journal of Cardiovascular Development and Disease
#18
JOURNAL ARTICLE
Khushboo Goel, Mehrnaz Maleki-Fischbach, M Patricia George, Darlene Kim, John Richards, Robert A Wise, Karina A Serban
A 56-year-old man presented to the pulmonary clinic with dyspnea and hypoxemia on exertion. He was an avid biker and skier who had noticed a significant decrease in high-level physical activity over the past 3 years. He reported dyspnea, desaturations at altitudes higher than 9,000 feet, dry cough, tachycardia, and palpitations with exercise. Review of systems was also notable for gluten-intolerance, Raynaud's phenomenon, recurrent skin lesions and joint swelling, pain, and stiffness in the areas overlying the jaw, wrists, knees, and ankles (after capsaicin exposure)...
November 2021: Chest
#19
JOURNAL ARTICLE
Shoshana C Leftin Dobkin, Joseph M Collaco, Sharon A McGrath-Morrow
INTRODUCTION: Although prolonged respiratory symptoms following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been described in adults, data are emerging that children also experience long-term sequelae of coronavirus disease 2019 (COVID-19). The respiratory sequelae of COVID-19 in children remain poorly characterized. In this study we describe health data and respiratory findings in pediatric patients presenting with persistent respiratory symptoms following COVID-19...
December 2021: Pediatric Pulmonology
#20
JOURNAL ARTICLE
Jonathan Solaimanzadeh, Aaron Freilich, Michael R Sood
BACKGROUND: Coronavirus disease 2019 (COVID-19) has been shown to have extensive effects on the cardiovascular system. Its long-term cardiac manifestations, however, remain unclear. CASE PRESENTATION: We report the case of a Caucasian patient with a mild and self-limited presentation of COVID-19, with subsequent development, months later, of exertional dyspnea and non-sustained ventricular tachycardia, long after resolution of his illness and after returning to aerobic exercise...
May 28, 2021: Journal of Medical Case Reports
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