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https://www.readbyqxmd.com/read/28231555/edge-preserving-denoising-for-intra-operative-cone-beam-ct-in-endovascular-aneurysm-repair
#1
Yi Liu, Miguel Castro, Mathieu Lederlin, Huazhong Shu, Adrien Kaladji, Pascal Haigron
C-arm cone-beam computed tomography (CBCT) acquisition during endovascular aneurysm repair (EVAR) is an emergent technology with more and more applications. It offers real time imaging with a stationary patient and provides 3-D information to achieve guidance of intervention. However, there is growing concern on the overall radiation doses delivered to patients all along the endovascular management due to pre-, intra-, and post-operative X-ray imaging. Manufactures may have their low dose protocols to realize reduction of radiation dose, but CBCT with a low dose protocol has too many artifacts, particularly streak artifacts, and decreased contrast-to-noise ratio (CNR)...
January 30, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28229527/melanotransferrin-new-homolog-genes-and-their-differential-expression-during-intestinal-regeneration-in-the-sea-cucumber-holothuria-glaberrima
#2
Josué Hernández-Pasos, Griselle Valentín-Tirado, José E García-Arrarás
Melanotransferrin (MTf) is a protein associated with oncogenetic, developmental, and immune processes which function remains unclear. The MTf gene has been reported in numerous vertebrate and invertebrate species, including echinoderms. We now report the finding of four different MTfs in the transcriptome of the sea cucumber Holothuria glaberrima. Sequence studies and phylogenetic analyses were done to ascertain the similarities among the putative proteins and their relationship with other transferrin family members...
February 23, 2017: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/28224311/prevalence-incidence-and-sex-ratio-of-transsexualism-in-the-autonomous-region-of-madrid-spain-according-to-healthcare-demand
#3
Antonio Becerra-Fernández, José Miguel Rodríguez-Molina, Nuria Asenjo-Araque, María Jesús Lucio-Pérez, Miguel Cuchí-Alfaro, Eduardo García-Camba, Gilberto Pérez-López, Miriam Menacho-Román, María Carmen Berrocal-Sertucha, Domingo Ly-Pen, María Victorina Aguilar-Vilas
In recent years, different studies have provided estimates of the prevalence of transsexualism with very diverse results. The purpose of this study was to ascertain the prevalence, incidence, and sex ratio of transsexualism in the autonomous region of Madrid (Spain). A total of 1234 patients who attended from 2007 to the end of 2015 in the only Gender Identity Unit (GIU) in Madrid were analyzed. Sixty-three patients were excluded for various reasons; thus, 1171 could be included: 803 male-to-female (MtF) and 368 female-to-male (FtM) transsexual patients...
February 21, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28218276/natural-and-laboratory-mutations-in-kuzbanian-are-associated-with-zinc-stress-phenotypes-in-drosophila-melanogaster
#4
Hung Le Manh, Lain Guio, Miriam Merenciano, Quirze Rovira, Maite G Barrón, Josefa González
Organisms must cope with altered environmental conditions such as high concentrations of heavy metals. Stress response to heavy metals is mediated by the metal-responsive transcription factor 1 (MTF-1), which is conserved from Drosophila to humans. MTF-1 binds to metal response elements (MREs) and changes the expression of target genes. kuzbanian (kuz), a metalloendopeptidase that activates the evolutionary conserved Notch signaling pathway, has been identified as an MTF-1 target gene. We have previously identified a putatively adaptive transposable element in the Drosophila melanogaster genome, named FBti0019170, inserted in a kuz intron...
February 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28217493/outcome-and-preferences-in-male-to-female-subjects-with-gender-dysphoria-experience-from-eastern-india
#5
Anirban Majumder, Debmalya Sanyal
CONTEXT: Gender dysphoria (GD) is an increasingly recognized medical condition in India, and little scientific data on treatment outcomes are available. AIMS: Our objective is to study the therapeutic options including psychotherapy, hormone, and surgical treatments used for alleviating GD in male-to-female (MTF) transgender subjects in Eastern India. SUBJECTS AND METHODS: This is a retrospective study of treatment preferences and outcome in 55 MTF transgender subjects who were presented to the endocrine clinic...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28195744/-proprietary-processed-allografts
#6
Troy A Roberson, Jeffrey T Abildgaard, Douglas J Wyland, Paul C Siffri, Stephen P Geary, Richard J Hawkins, John M Tokish
BACKGROUND: The processing of allograft tissues in anterior cruciate ligament (ACL) reconstruction continues to be controversial. While high-dose irradiation of grafts has received scrutiny for high failure rates, lower dose irradiation and "proprietary-based" nonirradiated sterilization techniques have become increasingly popular, with little in the literature to evaluate their outcomes. Recent studies have suggested that the specifics of allograft processing techniques may be a risk factor for higher failure rates...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28178942/in-vitro-comparative-optical-bench-analysis-of-a-spherical-and-aspheric-optic-design-of-the-same-iol-model
#7
Tamer Tandogan, Gerd U Auffarth, Chul Y Choi, Stephanie Liebing, Christian Mayer, Ramin Khoramnia
BACKGROUND: To analyse objective optical properties of the spherical and aspheric design of the same intraocular lens (IOL) model using optical bench analysis. METHODS: This study entailed a comparative analysis of 10 spherical C-flex 570 C and 10 aspheric C-flex 970 C IOLs (Rayner Intraocular Lenses Ltd., Hove, UK) of 26 diopters [D] using an optical bench (OptiSpheric, Trioptics, Germany). In all lenses, we evaluated the modulation transfer function (MTF) at 50 lp/mm and 100 lp/mm and the Strehl Ratio using a 3-mm (photopic) and 4...
February 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28157935/non-telecentric-projection-lens-design-for-an-led-projector
#8
Wen-Shing Sun, Jui-Wen Pan
A newly designed non-telecentric projection zoom lens is proposed for a mini-projector with LED light sources. The projection lens consists of six spherical lenses. The zoom ratio of the projection lens is 1.1. At the wide condition, the working F/# can maintain at 2.4 and the throw ratio can operate at 1.23. The root mean square (RMS) spot sizes of all fields are smaller than 15 μm for all zoom ranges. The optical distortion and the TV distortion were suppressed to be smaller than 1.5% and 1%, respectively...
January 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28157896/zoom-lens-design-for-10-2-megapixel-aps-c-digital-slr-cameras
#9
Wen-Shing Sun, Pu-Yi Chu, Chuen-Lin Tien, Meng-Feng Chung
A zoom lens design for a 10.2-megapixel digital single-lens reflex (SLR) camera with an advanced photo system type-C (APS-C) CCD image sensor is presented. The proposed zoom lens design consists of four groups of 3× zoom lenses with a focal length range of 17-51 mm. In the optimization process, 107 kinds of Schott glass combined with 26 kinds of plastic materials, as listed in Code V, are used. The best combination of glass and plastic materials is found based on the n<sub>d</sub>-V<sub>d</sub> diagram...
January 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28151431/characterisation-of-noise-and-sharpness-of-images-from-four-digital-breast-tomosynthesis-systems-for-simulation-of-images-for-virtual-clinical-trials
#10
Alistair Mackenzie, Nicholas Marshall, Andria Hadjipanteli, David Dance, Hilde Bosmans, Kenneth Young
In-depth evaluation of the noise and sharpness characteristics of FujiFilm Innovality, GE SenoClaire, Hologic Selenia Dimensions and Siemens Inspiration digital breast tomosynthesis (DBT) systems was performed with the intention of improving image simulation for virtual clinical trials. Noise power spectra (NPS) and modulation transfer function curves (MTF) were measured for planar modes and for the first and central projections for DBT modes. In DBT mode, the x-ray beam was blocked for the projections before the central projection in order to remove the influence of lag and ghosting from the previous images...
February 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28149775/accommodation-in-human-eye-models-a-comparison-between-the-optical-designs-of-navarro-arizona-and-liou-brennan
#11
Georgios Zoulinakis, Jose Juan Esteve-Taboada, Teresa Ferrer-Blasco, David Madrid-Costa, Robert Montés-Micó
AIM: To simulate and compare accommodation in accommodative and non-accommodative human eye models. METHODS: Ray tracing and optical design program was used. Three eye models were designed and studied: the Navarro, the Arizona and the Liou-Brennan. In order to make the Navarro and Liou-Brennan models to accommodate, specific geometric parameters of the models were altered with values that were chosen from the literature. For the Arizona model, its' mathematical functions for accommodation were used for the same accommodative demands...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28125995/analysis-of-spatiotemporal-fidelity-in-quantitative-3d-first-pass-perfusion-cardiovascular-magnetic-resonance
#12
Lukas Wissmann, Alexander Gotschy, Claudio Santelli, Kerem Can Tezcan, Sandra Hamada, Robert Manka, Sebastian Kozerke
BACKGROUND: Whole-heart first-pass perfusion cardiovascular magnetic resonance (CMR) relies on highly accelerated image acquisition. The influence of undersampling on myocardial blood flow (MBF) quantification has not been systematically investigated yet. In the present work, the effect of spatiotemporal scan acceleration on image reconstruction accuracy and MBF error was studied using a numerical phantom and validated in-vivo. METHODS: Up to 10-fold scan acceleration using k-t PCA and k-t SPARSE-SENSE was simulated using the MRXCAT CMR numerical phantom framework...
January 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28117266/genotypes-and-haplotypes-of-the-estrogen-receptor-%C3%AE-gene-esr1-are-associated-with-female-to-male-gender-dysphoria
#13
Joselyn Cortés-Cortés, Rosa Fernández, Nerea Teijeiro, Esther Gómez-Gil, Isabel Esteva, Mari Cruz Almaraz, Antonio Guillamón, Eduardo Pásaro
INTRODUCTION: Gender dysphoria, a marked incongruence between one's experienced gender and biological sex, is commonly believed to arise from discrepant cerebral and genital sexual differentiation. With the discovery that estrogen receptor β is associated with female-to-male (FtM) but not with male-to-female (MtF) gender dysphoria, and given estrogen receptor α involvement in central nervous system masculinization, it was hypothesized that estrogen receptor α, encoded by the ESR1 gene, also might be implicated...
January 20, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28104971/anti-inflammatory-and-anti-nociceptive-activities-of-stem-bark-extracts-and-fractions-of-carpolobia-lutea-polygalaceae
#14
Lucky Legbosi Nwidu, Blessing Airhihen, Augustine Ahmadu
BACKGROUND: In Niger Delta, ethnomedicine hydroalcoholic extract of Carpolobia lutea (CL) (Polygalaceae) is used to relieve inflammatory pains. OBJECTIVES: The purpose of this study is to evaluate the anti-inflammatory and antinociceptive effects of ethanolic stem extract (ESE) and to fractionate the ESE for the elucidation of bioactive molecules. MATERIALS AND METHODS: The antinociceptive effects for ESE were tested against two noxious stimuli; chemical (acetic acid-induced writhing and formalin-induced pain) and thermal (hot plate) stimuli...
December 2016: Journal of Basic and Clinical Pharmacy
https://www.readbyqxmd.com/read/28089191/object-shape-dependency-of-in-plane-resolution-for-iterative-reconstruction-of-computed-tomography
#15
Tadanori Takata, Katsuhiro Ichikawa, Wataru Mitsui, Hiroyuki Hayashi, Kaori Minehiro, Keita Sakuta, Haruka Nunome, Kousuke Matsubara, Hiroki Kawashima, Yukihiro Matsuura, Toshifumi Gabata
The present study aimed to investigate whether the in-plane resolution property of iterative reconstruction (IR) of computed tomography (CT) data is object shape-dependent by testing columnar shapes with diameters of 3, 7, and 10cm (circular edge method) and a cubic shape with 5-cm side lengths (linear edge method). For each shape, objects were constructed of acrylic (contrast in Hounsfield units [ΔHU]=120) as well as a soft tissue equivalent material (ΔHU=50). For each shape, we measured the modulation transfer functions (MTFs) of IR and filtered back projection (FBP) using two multi-slice CT scanners at scan doses of 5 and 10mGy...
January 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28072394/three-dimensional-cascaded-system-analysis-of-a-50-%C3%A2%C2%B5m-pixel-pitch-wafer-scale-cmos-active-pixel-sensor-x-ray-detector-for-digital-breast-tomosynthesis
#16
C Zhao, N Vassiljev, A C Konstantinidis, R D Speller, J Kanicki
High-resolution, low-noise x-ray detectors based on the complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been developed and proposed for digital breast tomosynthesis (DBT). In this study, we evaluated the three-dimensional (3D) imaging performance of a 50 µm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). The two-dimensional (2D) angle-dependent modulation transfer function (MTF), normalized noise power spectrum (NNPS), and detective quantum efficiency (DQE) were experimentally characterized and modeled using the cascaded system analysis at oblique incident angles up to 30°...
March 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28069140/the-comparison-of-radiography-and-point-of-care-ultrasonography-in-the-diagnosis-and-management-of-metatarsal-fractures
#17
Nalan Kozaci, Mehmet Oguzhan Ay, Mustafa Avci, Inan Beydilli, Sadullah Turhan, Eda Donertas, Ertan Ararat
OBJECTIVE: It was aimed to compare the efficacy of point-of-care ultrasonography (POCUS) with radiography in the diagnosis and management of metatarsal fracture (MTF). METHODS: Patients aged 5-55 years admitted to emergency room due to low-energy, simple extremity trauma and had a suspected MTF, were included in this prospective study. Patients were evaluated by two different emergency physicians in the emergency room. The first physician performed POCUS examination...
February 2017: Injury
https://www.readbyqxmd.com/read/28064140/reduced-radiation-dose-and-improved-image-quality-using-a-mini-mobile-digital-imaging-system-in-a-neonatal-intensive-care-unit
#18
Tae-Hoon Kim, Jong-Hyun Ryu, Chang-Won Jeong, Hong Young Jun, Dong-Woon Heo, Seung Hyun Lee, Yeon Kyun Oh, Mi-Jung Lee, Kwon-Ha Yoon
This study was aimed to assess the radiation dose and image quality of a mini-mobile digital imaging (mini-DI) system for neonatal chest radiography and compared to conventional digital radiography (DR). A total of 64 neonates were examined and anatomical landmarks were assessed. The entrance surface dose of mini DI and conventional DR was 26.64±0.15 μGy and 49.11±1.46 μGy, respectively (p<0.001). The mean SNR values for mini-DI and DR were 233.2±5.1 and 31.6±1.2, and 10% MTF values were 131 and 161μm...
December 6, 2016: Clinical Imaging
https://www.readbyqxmd.com/read/28060999/statistical-image-domain-multi-material-decomposition-for-dual-energy-ct
#19
Yi Xue, Ruoshui Ruan, Xiuhua Hu, Yu Kuang, Jing Wang, Yong Long, Tianye Niu
PURPOSE: Dual-energy CT (DECT) enhances tissue characterization because of its basis material decomposition capability. In addition to conventional two-material decomposition from DECT measurements, multi-material decomposition (MMD) is required in many clinical applications. To solve the ill-posed problem of reconstructing multiple-material images from dual-energy measurements, additional constraints are incorporated into the formulation, including volume and mass conservation and the assumptions that at most three materials in each pixel and various material types among pixels...
January 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28048864/su-f-j-41-experimental-validation-of-a-cascaded-linear-system-model-for-mvcbct-with-a-multi-layer-epid
#20
Y Hu, R Fueglistaller, J Rottmann, M Myronakis, A Wang, D Shedlock, D Morf, J Star-Lack, R Berbeco
PURPOSE: The purpose of this study was to validate the use of a cascaded linear system model for MV cone-beam CT (CBCT) using a multi-layer (MLI) electronic portal imaging device (EPID) and provide experimental insight into image formation. A validated 3D model provides insight into salient factors affecting reconstructed image quality, allowing potential for optimizing detector design for CBCT applications. METHODS: A cascaded linear system model was developed to investigate the potential improvement in reconstructed image quality for MV CBCT using an MLI EPID...
June 2016: Medical Physics
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