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https://www.readbyqxmd.com/read/27881835/leptospirosis-associated-severe-pulmonary-hemorrhagic-syndrome-with-lower-back-pain-as-an-initial-symptom
#1
Mads Madsen Søndergaard, Amela Tursunovic, Peter Thye-Rønn, Jacob Christian Bang, Inger Marie Jensen Hansen
BACKGROUND Leptospirosis is a zoonosis transmitted through urine of infected animals. Symptoms range from mild influenza-like symptoms to severe pulmonary hemorrhagic syndrome (SPHS); the latter are often fatal. The serogroup distribution in Denmark has changed from 1988 to 2012, with Icterohaemorrhagiae and Sejroe now being predominant. CASE REPORT A 45-year-old Danish woman living in an area endemic for Hanta virus, without prior medical history, was admitted because of lower back pain radiating to the left hip, fever, headache, nausea, and malaise...
November 24, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27455967/peptide-based-viral-detection-systems-for-effective-diagnosis-of-common-viral-infections-in-india
#2
Ushanandini Mohanraj, Suresh Chander, Yashwant G Chavan
Accurate and swift detection of viruses causing diseases in humans represent continuous challenges to diagnostic and epidemiological research. Efficient and rapid diagnosis is also crucial for effective implication of diseases management strategies. Multitude approaches attempted to identify individual viruses, includes serological assays and molecular methods. Detection assays based on peptides have become increasingly substantial and indispensable for its advantages over conventional methods. This review primarily outlines the progress made in peptide based diagnostics and the challenges for commonly found viral infections in India - Influenza Virus, Chikungunya virus, Dengue virus, Rotavirus, Japanese encephalitis virus (JEV), Epstein-Barr virus (EBV), Hanta Virus, Human Immunodeficiency virus (HIV) and Hepatitis C Virus...
July 24, 2016: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/27420807/aquatic-hazard-assessment-of-mon-0818-a-commercial-mixture-of-alkylamine-ethoxylates-commonly-used-in-glyphosate-containing-herbicide-formulations-part-2-roles-of-sediment-temperature-and-capacity-for-recovery
#3
Jose L Rodriguez-Gil, Ryan Prosser, Gregory Hanta, David Poirier, Linda Lissemore, Mark Hanson, Keith Solomon
A series of toxicity tests with the surfactant MON 0818 were performed: 1) in the presence of sediment for benthic invertebrates and fish: 2) to examine the recovery capacity of Daphnia magna and four primary producers after a pulse (24 h) exposure, and; 3) to examine the potential effect of increased water temperature on toxicity of MON 0818 to two cold-water fishes. In the presence of sediment, no acute (24-h) mortality was observed for three of the five species up to 10 mg L(-1) . The EC50s for the other two species were significantly greater than for water-only tests...
July 15, 2016: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/27372943/abnormalities-in-the-metabolism-of-fatty-acids-and-triacylglycerols-in-the-liver-of-the-goto-kakizaki-rat-a-model-for-non-obese-type-2-diabetes
#4
Minako Karahashi, Yuko Hirata-Hanta, Kohei Kawabata, Daisuke Tsutsumi, Misaki Kametani, Nanako Takamatsu, Takeshi Sakamoto, Tohru Yamazaki, Satoshi Asano, Atsushi Mitsumoto, Yoichi Kawashima, Naomi Kudo
The Goto-Kakizaki (GK) rat is widely used as an animal model for spontaneous-onset type 2 diabetes without obesity; nevertheless, little information is available on the metabolism of fatty acids and triacylglycerols (TAG) in their livers. We investigated the mechanisms underlying the alterations in the metabolism of fatty acids and TAG in their livers, in comparison with Zucker (fa/fa) rats, which are obese and insulin resistant. Lipid profiles, the expression of genes for enzymes and proteins related to the metabolism of fatty acid and TAG, de novo synthesis of fatty acids and TAG in vivo, fatty acid synthase activity in vitro, fatty acid oxidation in liver slices, and very-low-density-lipoprotein (VLDL)-TAG secretion in vivo were estimated...
August 2016: Lipids
https://www.readbyqxmd.com/read/27175497/-optimization-of-elisa-and-immunoblot-methods-for-the-detection-of-igg-antibodies-against-old-world-hantaviruses-in-wild-rodents
#5
Ceylan Polat, Ahmet Karataş, Mustafa Sözen, Ferhat Matur, Hakan Abacıoğlu, Mehmet Ali Öktem
Hantaviruses infect humans via inhalation of viral particles in infected rodents' secretions such as saliva, urine and faeces or via direct contact with infected rodents. The rodent species that are known as the carriers of Dobrava (DOBV), Puumala (PUUV), Saaremaa (SAAV), Tula (TULV) and Seoul (SEOV) viruses are found in our country. The presence of specific antibodies against hantaviruses have been demonstrated in rodents collected from Black Sea and Aegean Regions of Turkey in 2004 for the first time. The first hantavirus-related hemorrhagic fever with renal syndrome (HFRS) cases were reported in Black Sea region in 2009...
April 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/27074970/association-of-serum-albumin-level-and-mortality-in-premature-infants
#6
Birgin Torer, Deniz Hanta, Ece Yapakci, Zeynel Gokmen, Ayse Parlakgumus, Hande Gulcan, Aylin Tarcan
BACKGROUND: Hypoalbuminemia has been proven to be a powerful predictor of mortality in adult patients. However, prognostic value of serum albumin in neonates is not clear. OBJECTIVE: To assess the relationship between serum albumin level within the first day of life and outcome in preterm infants born before 32 weeks of gestation. METHODS: The study was conducted prospectively in Baskent University Hospital between October 2008 and November 2009...
April 13, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/26829333/determination-of-glyphosate-and-its-metabolite-in-emergency-room-in-korea
#7
Joseph Han, Hantae Moon, Youngki Hong, Songhee Yang, Won-Joon Jeong, Kwang-Sik Lee, Heesun Chung
The number of glyphosate intoxication cases has been increased after the regulation of paraquat. Unfortunately, there are no reports on the potential concentration of glyphosate for those acute intoxicated patients admitted to emergency rooms and the correlation between the concentration of glyphosate and clinical symptoms in Korea up to our knowledge. As a nonselective herbicide, analysis of glyphosate requires derivatization because of its amphoteric and strongly polar nature. In order to develop a method to determine the concentration of glyphosate and its metabolite, aminomethylphosphonic acid (AMPA) in blood samples without derivatization, liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) was utilized with a hydrophilic interaction chromatography (HILIC) column...
August 2016: Forensic Science International
https://www.readbyqxmd.com/read/26701941/an-aggressive-parenteral-nutrition-protocol-improves-growth-in-preterm-infants
#8
Birgin Törer, Deniz Hanta, Zeliha Özdemir, Bilin Çetinkaya, Hande Gülcan
The objective of this study was to compare postnatal growth and clinical outcomes of preterm infants after an adjustment in amino acid and lipid administration practice. The study was conducted retrospectively in preterm infants with a birth weight < 1250 g for the periods January-June 2007 and June-November 2010. In 2007, amino acid solution was initiated at 2 g/kg/ day on the first day of life and advanced 1 g/kg/day to a maximum of 3 g/kg/day; lipid solution was initiated at 1 g/kg/day on the first day of life and advanced 0...
May 2015: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/26673444/ultrasound-accelerated-thrombolysis-may-be-an-effective-and-safe-treatment-modality-for-intermediate-risk-submassive-pulmonary-embolism
#9
Caglar Ozmen, Ali Deniz, Rabia Eker Akilli, Onur Sinan Deveci, Caglar Emre Cagliyan, Halil Aktas, Aziz İnan Celik, Ayca Acikalin Akpinar, Nezihat Rana Disel, Hüseyin Tugsan Balli, İsmail Hanta, Mesut Demir, Ayhan Usal, Mehmet Kanadasi
Pulmonary embolism (PE) is a potentially life-threatening condition and the fact that 90% of PE originate from lower limb veins highlights the significance of early detection and treatment of deep vein thrombosis. Massive/high risk PE involving circulatory collapse or systemic arterial hypotension is associated with an early mortality rate of approximately 50%, in part from right ventricular (RV) failure. Intermediate risk/submassive PE, on the other hand, is defined as PE-related RV dysfunction, troponin and/or B-type natriuretic peptide elevation despite normal arterial pressure...
2016: International Heart Journal
https://www.readbyqxmd.com/read/26626232/chemical-constituents-of-the-soft-corals-sinularia-vanderlandi-and-sinularia-gravis-from-the-coast-of-madagascar
#10
Marie Pascaline Rahelivao, Margit Gruner, Tilo Lübken, Daut Islamov, Olga Kataeva, Hanta Andriamanantoanina, Ingmar Bauer, Hans-Joachim Knölker
The crude extracts of the Madagascan soft corals Sinularia vanderlandi and Sinularia gravis (Alcyoniidae) showed activity against Plasmodium falciparum which led us to study their chemical constituents. The new cadinane-type sesquiterpenoid vanderlandin (1) has been obtained from S. vanderlandi along with 24-methylenecholesterol (2). Four new compounds, the spatane-type diterpenoid gravilin (3), the monoalkylmonoacylglycerol 4, the dihomoditerpenoid ketone 5, and isodecaryiol (9), along with the three known compounds (+)-(S)-geranyllinalool (6), (-)-(R)-nephthenol (7), and 11,12-epoxysarcophytol A (8) have been isolated from the methanol extract of S...
January 21, 2016: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/26613228/idiopathic-central-diabetes-insipidus-presenting-in-a-very-low-birth-weight-infant-successfully-managed-with-lyophilized-sublingual-desmopressin
#11
Deniz Hanta, Birgin Törer, Fatih Temiz, Hasan Kılıçdağ, Mahmut Gökçe, Özlem Erdoğan
Neonatal central diabetes insipidus (DI) is an extremely rare disorder that can cause severe morbidity and mortality. We have reported a very low birth weight infant with idiopathic central DI presenting in the first month of life who was successfully treated with sublingual desmopressin therapy. In this report, we emphasize that central DI should be kept in mind in an infant with unexplained hypernatremia and polyuria. Timely diagnosis and treatment with lyophilized desmopressin may prevent severe morbidity and mortality...
January 2015: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/26358714/brown-algae-phaeophyceae-from-the-coast-of-madagascar-preliminary-bioactivity-studies-and-isolation-of-natural-products
#12
Marie Pascaline Rahelivao, Margit Gruner, Hanta Andriamanantoanina, Ingmar Bauer, Hans-Joachim Knölker
Eight species of brown algae (Phaeophyceae) from the coast of Madagascar have been investigated for their chemical constituents. Fucosterol (3) was obtained as the most abundant compound. The brown alga Sargassum ilicifolium was the source for the first isolation of the terpenoid C27-alcohol 1,1',2-trinorsqualenol (1) from marine sources. From S. incisifolium we isolated the highly unsaturated glycolipid 1-O-palmitoyl-2-O-stearidonoyl-3-O-β-D-galactopyranosylglycerol (4) and we report the first full assignment of its (1)H and (13)C NMR data...
October 2015: Natural Products and Bioprospecting
https://www.readbyqxmd.com/read/26291525/stat2-knockout-syrian-hamsters-support-enhanced-replication-and-pathogenicity-of-human-adenovirus-revealing-an-important-role-of-type-i-interferon-response-in-viral-control
#13
Karoly Toth, Sang R Lee, Baoling Ying, Jacqueline F Spencer, Ann E Tollefson, John E Sagartz, Il-Keun Kong, Zhongde Wang, William S M Wold
Human adenoviruses have been studied extensively in cell culture and have been a model for studies in molecular, cellular, and medical biology. However, much less is known about adenovirus replication and pathogenesis in vivo in a permissive host because of the lack of an adequate animal model. Presently, the most frequently used permissive immunocompetent animal model for human adenovirus infection is the Syrian hamster. Species C human adenoviruses replicate in these animals and cause pathology that is similar to that seen with humans...
August 2015: PLoS Pathogens
https://www.readbyqxmd.com/read/26233088/occurrence-and-maintenance-of-hantavirus-infections-among-rodent-populations-in-their-natural-habitat-results-of-a-field-study-from-podkarpackie-province-poland-2010-2012
#14
Małgorzata Sadkowska-Todys, Dorota Dudek-Godeau, Sylwia Kamińska, Anna Baumann-Popczyk, Michał Czerwiński, Bożena Kucharczyk, Andrzej Zieliński
UNLABELLED: Human cases of hantavirus infection have been reported annually in Poland's Podkarpackie province, since 2007. In 2014 the number of cases reported significantly increased prompting a rise in studies focusing on the infection. OBJECTIVE: The purpose of this study was to evaluate the prevalence, maintenance and the dynamics of hantavirus infection among rodent species, including the bank vole (Myodes glareolus) and yellow-necked mouse (Apodemus flavicollis) which act as reservoirs of hantavirus in the environment...
2015: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/26198236/red-algae-rhodophyta-from-the-coast-of-madagascar-preliminary-bioactivity-studies-and-isolation-of-natural-products
#15
Marie Pascaline Rahelivao, Margit Gruner, Hanta Andriamanantoanina, Bakolinirina Andriamihaja, Ingmar Bauer, Hans-Joachim Knölker
Several species of red algae (Rhodophyta) from the coastal regions of Madagascar have been investigated for their natural products. The most abundant compound was cholesterol (5) in combination with a series of oxidized congeners. The brominated indoles 1-3 along with the sesquiterpene debilone (4) have been isolated from Laurencia complanata. For the first time, debilone (4) has been obtained from a marine plant. From the methanol extract of Calloseris sp., we have achieved the second isolation of the unusual A-ring contracted steroids (-)-2-ethoxycarbonyl-2β-hydroxy-A-nor-cholest-5-en-4-one (9) and phorbasterone B (10)...
July 2015: Marine Drugs
https://www.readbyqxmd.com/read/25731653/is-umbilical-cord-milking-always-an-advantage
#16
RANDOMIZED CONTROLLED TRIAL
Hasan Kilicdag, Hande Gulcan, Deniz Hanta, Birgin Torer, Zeynel Gokmen, Sonay Incesoy Ozdemir, Bulent Ali Antmen
OBJECTIVE: The role of cord milking as an alternative to delayed cord clamping is an area that requires more research. Purpose of this clinical trial was to investigate the impact of umbilical cord milking on the absolute neutrophil counts (ANCs) and the neutropenia frequency of preterm infants. METHODS: Fifty-eight pregnant women were randomly assigned to one of the umbilical cord milking and control groups. A total of 54 preterm infants (gestational age ≤ 32 weeks) were enrolled into the study...
2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/25591623/current-immunological-and-molecular-tools-for-leptospirosis-diagnostics-vaccine-design-and-biomarkers-for-predicting-severity
#17
REVIEW
Senaka Rajapakse, Chaturaka Rodrigo, Shiroma M Handunnetti, Sumadhya Deepika Fernando
Leptospirosis is a zoonotic spirochaetal illness that is endemic in many tropical countries. The research base on leptospirosis is not as strong as other tropical infections such as malaria. However, it is a lethal infection that can attack many vital organs in its severe form, leading to multi-organ dysfunction syndrome and death. There are many gaps in knowledge regarding the pathophysiology of leptospirosis and the role of host immunity in causing symptoms. This hinders essential steps in combating disease, such as developing a potential vaccine...
2015: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/25530620/genetic-diversity-of-talpa-europaea-and-nova-hanta-virus-nvav-in-france
#18
Jean-Pierre Hugot, Se Hun Gu, Carlos Feliu, Jacint Ventur, Alexis Ribas, Jerôme Dormion, Richard Yanagihara, Violaine Nicolas
Nova hantavirus (NVAV) was first identified in a single European mole (Talpa europaea), captured in Hungary. Analysis of lung tissues from 94 moles captured in France revealed NVAV in 50%. Based on the genetic diversity of the cytochrome b mtDNA, moles collected in Poitiers and Bordeaux were more closely related to the Iberian mole (T. occidentalis), a species previously assumed to be restricted to the Iberian Peninsula. Several hypotheses are discussed to explain these observations: 1) presence of hitherto unnoticed T...
2014: Bulletin de L'Académie Vétérinaire de France
https://www.readbyqxmd.com/read/25528917/prevalence-of-antibodies-against-selected-zoonotic-agents-in-forestry-workers-from-eastern-and-southern-poland
#19
Wioletta Żukiewicz-Sobczak, Jacek Zwoliński, Jolanta Chmielewska-Badora, Elżbieta Monika Galińska, Grażyna Cholewa, Ewelina Krasowska, Jerzy Zagórski, Andrzej Wojtyła, Krzysztof Tomasiewicz, Teresa Kłapeć
INTRODUCTION AND OBJECTIVE: Due to the nature of their work, foresters are exposed to many infectious pathogens from the wildlife reservoir. The primary aim of this study was to assess their contact with these pathogens. MATERIAL AND METHODS: Sera and antibodies, mainly of IgG class against selected infectious factors, collected from a group of 216 employees of National Forests from eastern and southern Poland, were investigated. RESULTS: Antibodies to Anaplasma phagocytophilum were detected in 64 sera (29...
2014: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/25286630/-a-hantavirus-killed-an-israeli-researcher-hazards-while-working-with-wild-animals
#20
Eitan Israeli
An Israeli researcher working in Finland with Bank Voles, contracted an infectious viral disease and died. This was a rare event, but it is important to learn about this class of viruses and to be aware of the hazards while working in the field in close contact with wild animals. The virus termed Puumala belongs to the genus Hanta from the Bunyaviridae family. The natural reservoir is rodents, mice, rats and Bank Votes for the Puuamala strain. The disease is termed HFRS (hemorrhagic fever with renal syndrome), is prevalent in Asia and Europe, affecting 200,000 people a year, with 5-15% percent mortality (although in Finland mortality rate is 0...
August 2014: Harefuah
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