Kathize Betti Lira, Renan Senandes Delvaux, Felipe Abatti Spadini, Luis Henrique Hauschild, Rafael Oliveira Ceron, Fernando Anschau, Luciane Kopittke, Juarez Rode, Rafael Antônio Widholzer Rey, Estefania Inez Wittke, Alfeu Roberto Rombaldi, Eduardo Cambruzzi, Eron Rodrigues Cunha Lopes, Adriana Silveira Almeida
BACKGROUND: Myocardial protection is crucial for successful cardiac surgery, as it prevents heart muscle damage that can occur during the procedure. Prolonged hypoxia without proper protection can lead to adenosine triphosphate consumption, microvilli loss, blister formation, and edema. Custodiol, del Nido, and modified del Nido are single-dose cardioplegic solutions with proven safety and significance in modern surgery. While each has been independently assessed for patient outcomes, limited research directly compares them...
February 29, 2024: Journal of Thoracic Disease