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Steroid induced cataract

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https://www.readbyqxmd.com/read/29133632/uveal-effusion-syndrome-in-104-eyes-response-to-corticosteroids-the-2017-axel-c-hansen-lecture
#1
Carol L Shields, Kelsey Roelofs, Maura Di Nicola, Kareem Sioufi, Arman Mashayekhi, Jerry A Shields
PURPOSE: The purpose of the study was to investigate the corticosteroids for uveal effusion syndrome (UES). METHODS: Retrospective series of 104 eyes with UES treated with oral corticosteroids (OCS), periocular corticosteroids (PCS), topical corticosteroids (TCS), or observation (OBS). Main outcome measure was UES resolution. RESULTS: Of 104 eyes, treatment included OCS (n = 27), PCS (n = 12), TCS (n = 11), and OBS (n = 54). A comparison of the four groups (OCS vs...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29040121/outcomes-and-rationale-of-excision-and-mucous-membrane-grafting-in-palpebral-vernal-keratoconjunctivitis
#2
Geetha Iyer, Shweta Agarwal, Bhaskar Srinivasan
PURPOSE: To report outcomes of mucous membrane grafting (MMG) for refractory giant papillae in vernal keratoconjunctivitis. METHODS: Eleven eyes of 6 patients having giant papillae and recurrent shield ulcers refractory to topical medications, cryotherapy, and supratarsal steroid injections and shave excision of papillae underwent surgical resection of the giant papillae with MMG. Average occurrence of shield ulcers was twice per eye per year before the procedure with 50% of eyes having steroid-induced cataract and glaucoma...
October 13, 2017: Cornea
https://www.readbyqxmd.com/read/28924446/use-of-intravitreal-dexamethasone-in-a-case-of-anterior-ischemic-optic-neuropathy
#3
Raffaele Nuzzi, Francesca Monteu
Nowadays there is no unique and well-established treatment for nonarteritic anterior ischemic optic neuropathy, despite being the main acute pathology that affects the optic nerve in the elderly population and often resulting in a significant loss of visual acuity. The effectiveness of oral steroids is still under debate in the international literature, although many studies show that patients treated with high doses of systemic corticosteroids have a significantly higher chance of improved visual acuity and visual fields...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28924342/steroid-induced-glaucoma-an-avoidable-irreversible-blindness
#4
REVIEW
Sonia Phulke, Sushmita Kaushik, Savleen Kaur, S S Pandav
Steroids are a group of anti-inflammatory drugs, commonly used to treat ocular and systemic conditions. Unmonitored use of steroids especially in eye drop formulations is common in situations when it is easily available over-the-counter, resulting in undesirable side effects. Among the ocular side effects, cataract and glaucoma are common. Steroid-induced ocular hypertension was reported in 1950, when long-term use of systemic steroid was shown to increase the intraocular pressure (IOP). Chronic administration of steroids in any form with raised IOP can cause optic neuropathy resulting in steroid-induced glaucoma...
May 2017: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/28524138/-cortisol-levels-in-plasma-and-aqueous-humour-of-patients-with-steroid-induced-and-other-glaucomas
#5
E M Kasimov, F A Aghaeva
The paper describes the role of endogenous glucocorticoids in the pathogenesis of open-angle glaucoma. As to steroid-induced glaucoma (SG), however, indicators of systemic and local cortisol metabolism are yet underinvestigated. Aim - to determine and compare systemic (plasma) and local (aqueous humour) cortisol concentrations in patients with SG and other types of glaucoma (OTG). MATERIAL AND METHODS: A prospective analysis was conducted in 64 patients who underwent plasma and aqueous humor sampling...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28511470/study-on-steroid-induced-ocular-findings-in-children-with-nephrotic-syndrome
#6
Vijay Agrawal, Kusum Devpura, Laxmikant Mishra, Sajan Agarwal
INTRODUCTION: Long term use of corticosteroids in Nephrotic Syndrome (NS) is associated with ocular complications such as Posterior Subcapsular Cataract (PSC), glaucoma, increased intra-ocular pressure, ptosis, mydriasis, eyelid skin atrophy, keratisis, thinning of cornea and sclera, repeated hordeolum exacerbations. AIM: To determine ocular abnormalities in children with NS and their association with steroid dosing and duration. MATERIALS AND METHODS: Hundred patients with NS in the age group of 2-18 years, with no evidence of other systemic disease, were considered for the study...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28448730/retinal-manifestations-of-juvenile-dermatomyositis-case-report-of-bilateral-diffuse-chorioretinopathy-with-paracentral-acute-middle-maculopathy-and-review-of-the-literature
#7
Rene Y Choi, Russell J Swan, Aimee Hersh, Albert T Vitale
PURPOSE: To review a case of bilateral diffuse chorioretinopathy as a presenting sign of juvenile dermatomyositis (JDM) and review the literature regarding retinal manifestations associated with this disease. METHODS: Review of case record and literature regarding retinal manifestations related to juvenile dermatomyositis. RESULTS: A 13-year-old girl presented with bilateral diffuse chorioretinopathy as the presenting sign of juvenile dermatomyositis...
April 27, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28448293/trabeculectomy-or-transscleral-cyclophotocoagulation-as-initial-treatment-of-secondary-childhood-glaucoma-in-northern-tanzania
#8
COMPARATIVE STUDY
Achim Fieß, Peter Shah, Freda Sii, Furahini Godfrey, Joe Abbott, Richard Bowman, Jacqueline Bauer, Stefan Dithmar, Heiko Philippin
PURPOSE: The purpose is to describe the outcome of trabeculectomy with transscleral cyclophotocoagulation (TSCPC) as an initial intervention for secondary childhood glaucoma in Northern Tanzania. METHODS: A retrospective, consecutive case series was analyzed of all children with secondary childhood glaucoma who underwent initial trabeculectomy or TSCPC between 2000 and 2013 at a referral eye unit in Northern Tanzania. Retrospective data were collected on causes of glaucoma, intraocular pressure (IOP), visual acuity, complications, and subsequent interventions...
July 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28430806/incidence-and-risk-factors-for-post-penetrating-keratoplasty-glaucoma-a-systematic-review-and-meta-analysis
#9
REVIEW
Suqian Wu, Jianjiang Xu
OBJECTIVES: To establish the incidence and risk factors for post penetrating keratoplasty glaucoma (PKKG). METHODS: Studies published between 1947 and 2016 regarding penetrating keratoplasty (PK) were identified using an electronic search and reviewed. For search purpose, PKKG was defined as ocular hypertension (> 21mmHg) after PK. The incidence and risk factors of PKKG were extracted for all studies. Pooled incidence, odd ratios (ORs) and 95% confidence intervals (CIs) were calculated...
2017: PloS One
https://www.readbyqxmd.com/read/28366370/comparison-of-prednisolone-acetate-1-0-and-difluprednate-ophthalmic-emulsion-0-05-after-cataract-surgery-incidence-of-postoperative-steroid-induced-ocular-hypertension
#10
Marius A Tijunelis, Erica Person, Leslie M Niziol, David C Musch, Paul Ernest, Madeline McBain, Shahzad I Mian
PURPOSE: To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0.05% and prednisolone acetate 1.0%. SETTING: TLC Eyecare and Laser Centers, Jackson, Michigan, USA. DESIGN: Retrospective chart review. METHODS: The outcomes of consecutive patients who had uneventful cataract surgery from April 2013 to September 2013 and used prednisolone acetate postoperatively were compared with the outcomes of consecutive patients who had uneventful cataract surgery from June 2014 to October 2014 and used difluprednate postoperatively...
February 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28161921/prevalence-of-steroid-induced-cataract-and-glaucoma-in-chronic-obstructive-pulmonary-disease-patients-attending-a-tertiary-care-center-in-india
#11
Tirupati Nath, Subham Sinha Roy, Himanshu Kumar, Rachit Agrawal, Santosh Kumar, S K Satsangi
PURPOSE: Exposure to corticosteroids is known to be associated with an increased risk of cataract and glaucoma. This study was undertaken to determine the prevalence of steroid-induced cataract and glaucoma in patients with chronic obstructive pulmonary disease (COPD) and to assess a dose-response relationship between them. DESIGN: This was a prospective observational study. METHODS: We identified all COPD patients aged 50 years or older, with minimum steroid exposure of 4 months and on inhaled corticosteroids from March 2014 to March 2015...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28130595/the-comparative-efficacy-and-safety-of-topical-non-steroidal-anti-inflammatory-drugs-for-the-treatment-of-anterior-chamber-inflammation-after-cataract-surgery-a-systematic-review-and-network-meta-analysis
#12
REVIEW
Ping Duan, Yong Liu, Jiawen Li
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of anti-inflammatory drugs that are used in ophthalmologic surgery. These drugs do not have a steroid structure, but can inhibit surgery-induced miosis, anterior chamber inflammation, and cystoid macular edema (CME). However, the application of NSAIDs remains controversial. Therefore, we performed a meta-analysis to assess the efficacy and safety of NSAIDs for the treatment of anterior chamber inflammation after cataract surgery...
April 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28129292/persistent-epithelial-defects-and-corneal-opacity-after-collagen-cross-linking-with-substitution-of-dextran-t-500-with-dextran-sulfate-in-compounded-topical-riboflavin
#13
Roland Höllhumer, Stephanie Watson, Peter Beckingsale
PURPOSE: Collagen cross-linking (CXL) is a commonly performed procedure to prevent the progression of keratoconus. Riboflavin is an essential part of the procedure, which facilitates both the cross-linking process and protection of intraocular structures. Dextran can be added to riboflavin to create an isotonic solution. This case report highlights the importance of compounding riboflavin with the correct dextran solution. METHODS: A retrospective case series. RESULTS: Six eyes of 4 male patients with keratoconus aged from 20 to 38 years underwent CXL with substitution of 20% dextran (T-500) with 20% dextran sulfate in a compounded riboflavin 0...
March 2017: Cornea
https://www.readbyqxmd.com/read/28101045/express-mini-shunt-as-a-treatment-alternative-for-medically-uncontrolled-steroid-induced-glaucoma-in-a-pediatric-patient
#14
Bonnie Nga Kwan Choy, Mandy Oi Man Wong, Jonathan Cheuk Hung Chan, Connie Hong Yee Lai, Jimmy Shiu Ming Lai
This case report illustrates the use of ExPRESS mini-shunt in a pediatric glaucoma patient. We describe the management of steroid-induced glaucoma with ExPRESS mini-shunt in a 9-year-old boy with allergic keratoconjunctivitis. The intraocular pressure of both of his eyes was uncontrolled with medical and laser treatment. Both eyes were treated with ExPRESS mini-shunt and mitomycin-C. Transient overfiltration with postoperative hypotony occurred in both eyes and resolved after 2 weeks. One year postoperatively, intraocular pressure was maintained below 21 mm Hg without medication in 1 eye...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28100180/extensive-bilateral-corneal-edema-6%C3%A2-weeks-after-cataract-surgery-keratopathy-due-to-asclepias-physocarpa-a-case-report
#15
Kazuki Matsuura, Shiro Hatta, Yuki Terasaka, Yoshitsugu Inoue
BACKGROUND: Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection. CASE PRESENTATION: A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 weeks after uneventful cataract surgery. We observed extensive hyperemia and corneal stromal edema with Descemet's folds in both eyes. After obtaining a detailed patient history, we diagnosed plant toxin-induced corneal edema due to Asclepias physocarpa, which can induce corneal edema by inhibiting the Na(+)/K(+) ATPase activity of the corneal endothelium...
January 18, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28007113/effect-of-postoperative-administration-of-nonsteroidal-antiinflammatory-drugs-and-steroids-on-the-conformational-changes-in-wound-healing-after-cataract-surgery
#16
Eun Young Choi, Hyun Goo Kang, Tae-Im Kim, Eung Kwoen Kim, Hyung Keun Lee
PURPOSE: To assess the changes in clear corneal incision (CCI) healing resulting from the postoperative administration of nonsteroidal antiinflammatory drugs (NSAIDs) or steroids using anterior segment optical coherence tomography (AS-OCT). SETTING: Institute of Vision Research, Department of Ophthalmology, Yonsei University, Seoul, South Korea. DESIGN: Prospective randomized comparative study. METHODS: Eyes having cataract surgery were randomly given an NSAID (bromfenac 0...
December 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27957367/bimatoprost-induced-serous-macular-detachment-after-cataract-surgery
#17
Swapnil Parchand, Subashini Kaliaperumal, Amit Kumar Deb, K Ramesh Babu, Renuka Srinivasan
We report a case of bimatoprost induced serous macular detachment and choroidal folds following uneventful cataract surgery. A 66-year-old male using topical bimatoprost in both eyes for open angle glaucoma underwent uneventful cataract surgery in the right eye. Postoperatively, he was restarted on topical bimatoprost and antibiotic-steroids combination drops. One week after surgery, he presented with conjunctival hyperemia, serous macular detachment, and choroidal folds at the posterior pole. Fundus fluorescein angiography showed perifoveal leaks in early stage with pooling of dye in late stage...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27621671/infectious-crystalline-keratopathy-caused-by-cladosporium-sp-after-penetrating-keratoplasty-a-case-report
#18
Ricardo Alexandre Stock, Elcio Luiz Bonamigo, Emeline Cadore, Rafael Allan Oechsler
BACKGROUND: Infectious crystalline keratopathy is a rare, progressive infection characterized by the insidious progression of branches and crystalline corneal opacities with minimal or no inflammation. This case report describes the evolution of an infectious crystalline keratopathy caused by Cladosporium sp., which developed after tectonic keratoplasty in a patient with a history of ocular trauma. CASE PRESENTATION: A 40-year-old Brazilian male was the victim of firework-induced trauma to the left eye, which resulted in a corneal laceration that could not be sutured as well as a severe traumatic cataract...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27608477/early-onset-steroid-induced-posterior-subcapsular-cataract-in-a-patient-with-common-variable-immunodeficiency-case-reports-and-review-of-literature
#19
REVIEW
H Marefat, H Abolhassani, M Ghareje Daghi, G Azizi, A Aghamohammadi
Purpose. To report early onset steroid induced posterior subcapsular cataract in a case of common variable immunodeficiency. Methods. Case report. Results. Here we report a 14-yearold male of steroid induced bilateral posterior subcapsular cataract in a common variable immunodeficiency patient with damaging mutations in Glutathione reductase gene, leading to hypersensitivity of patient to glucocorticoid (GC) products. Conclusions. In order to reduce the ocular side effects of the GCs there are some advisements, including a complete history, regular examination, GC should be prescribed in minimal dosage and minimal course, and as possible GC-sparing drugs should always be considered...
September 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27379189/aspergillus-fumigatus-endophthalmitis-with-necrotizing-scleritis-following-pars-plana-vitrectomy
#20
Anna M Gruener, Felicity Allen, Miles R Stanford, Elizabeth M Graham
We present a case of Aspergillus fumigatus endophthalmitis complicated by necrotizing scleritis in a 68-year-old man with diet-controlled diabetes, after retinal detachment repair. He was initially treated with systemic steroids for surgically induced necrotizing scleritis following routine pars plana vitrectomy. An additional diagnosis of endophthalmitis was made when the patient developed a hypopyon. Repeat vitreous culture isolated Aspergillus fumigatus. Symptoms improved following antifungal treatment leaving the patient with scleromalacia and an advanced postoperative cataract...
2016: Case Reports in Ophthalmological Medicine
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