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https://www.readbyqxmd.com/read/29166673/factors-related-to-acupuncture-response-in-patients-with-chronic-severe-functional-constipation-secondary-analysis-of-a-randomized-controlled-trial
#1
Xingyue Yang, Yan Liu, Bing Liu, Liyun He, Zhishun Liu, Yanshi Yan, Jia Liu, Baoyan Liu
BACKGROUND: Acupuncture has been demonstrated to be effective and safe for chronic severe functional constipation (CSFC). However, which patients with CSFC will have a better response to acupuncture remains unclear. OBJECTIVE: To explore factors related to acupuncture response in patients with CSFC. METHODS: We performed a secondary analysis of a previous multicenter randomized controlled trial consisting of a 2-week run-in period, 8-week treatment, and 12-week follow-up without treatment in which patients with CSFC were randomly allocated to an electroacupuncture group or a sham electroacupuncture group...
2017: PloS One
https://www.readbyqxmd.com/read/29166427/myxobolus-marajoensis-sp-n-myxosporea-myxobolidae-parasite-of-the-freshwater-catfish-rhamdia-quelen-from-the-brazilian-amazon-region
#2
Jacqueline Abrunhosa, José Ledamir Sindeaux-Neto, Ândrea Kely Dos Santos, Igor Hamoy, Edilson Matos
This study provides morphological and molecular data of a new parasite species found in the muscle layer of the intestinal tract of the South American silver catfish, Rhamdia quelen from Marajó Island region (Pará State, Brazil), an important fishery resource with recognized potential for fish farming. The morphology of these parasites was reanalyzed and phylogenetic analyses were run on their 18S rDNA gene sequences. The spores were morphologically distinct from those of other Myxobolus species described previously...
November 17, 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/29166321/adipose-lipolysis-unchanged-by-preexercise-carbohydrate-regardless-of-glycemic-index
#3
Daniel A Baur, Brandon D Willingham, Kyle A Smith, Jacob N Kisiolek, Margaret C Morrissey, Patrick G Saracino, Tristan J Ragland, Michael J Ormsbee
PURPOSE: To determine the impact of pre-exercise carbohydrate of different glycemic indices on subcutaneous abdominal adipose tissue (SCAAT) metabolism and running performance. METHODS: Ten trained male runners completed three experimental trials consisting of 30 min at 60% VO2max, 30 min at 75% VO2max, and a 5-km time trial (TT). Thirty min prior to exercise, participants consumed one of three beverages: 1) 75 g low glycemic index modified starch supplement (UCAN), 2) 75 g high glycemic index glucose-based supplement (G), or 3) a flavor-matched non-caloric placebo (PL)...
November 20, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29166287/assessment-of-genomic-inbreeding-in-polish-konik-horses
#4
S Kamiński, D M Hering, Z Jaworski, T Zabolewicz, A Ruść
The aim of this study was to assess the inbreeding coefficient of Polish Konik horses based on runs of homozygosity (ROH). Ninety six horses kept in 6 herds located across Poland were genotyped with the use of EquineSNP60 BeadChip (Illumina). SNP markers with a Minor Allele Frequency lower than 0.01 and SNPs assigned to chromosome X or Y were excluded from the study. A total of 50 708 SNPs were included for statistical analysis (SVS software, Golden Helix). The analysis showed that the population is in genetic equilibrium, with He and Ho estimates both equal to 0...
September 26, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/29165917/a-novel-multisite-confocal-system-for-rapid-ca-2-imaging-from-submicron-structures-in-brain-slices
#5
Luiza Filipis, Karima Ait Ouares, Philippe Moreau, Dimitrii Tanese, Valeria Zampini, Andrea Latini, Chun Bleau, Charlie Bleau, Jeremy Graham, Marco Canepari
In brain slices, resolving fast Ca(2+) fluorescence signals from submicron structures is typically achieved using two-photon or confocal scanning microscopy, an approach that limits the number of scanned points. The novel multiplexing confocal system presented here overcomes this limitation. This system is based on a fast spinning disk, a multimode diode laser and a novel high-resolution CMOS camera. The spinning disk, running at 20,000 rpm, has custom-designed spiral pattern that maximises light collection while rejecting out-of-focus fluorescence to resolve signals from small neuronal compartments...
November 22, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29165690/the-regulatory-g4-motif-of-the-kirsten-ras-kras-gene-is-sensitive-to-guanine-oxidation-implications-on-transcription
#6
Susanna Cogoi, Annalisa Ferino, Giulia Miglietta, Erik B Pedersen, Luigi E Xodo
KRAS is one of the most mutated genes in human cancer. It is controlled by a G4 motif located upstream of the transcription start site. In this paper, we demonstrate that 8-oxoguanine (8-oxoG), being more abundant in G4 than in non-G4 regions, is a new player in the regulation of this oncogene. We designed oligonucleotides mimicking the KRAS G4-motif and found that 8-oxoG impacts folding and stability of the G-quadruplex. Dimethylsulphate-footprinting showed that the G-run carrying 8-oxoG is excluded from the G-tetrads and replaced by a redundant G-run in the KRAS G4-motif...
November 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29165537/frailty-is-not-associated-with-mistreatment
#7
S D Piña-Escudero, J M A García-Lara, J A Avila-Funes
Muscle Frailty has been previously associated with increased vulnerability for adverse health-related outcomes that could lead to social consequences such as mistreatment. The aim of this cross-sectional study is to determine the association between frailty and mistreatment in 852 community-dwelling persons aged 70 or older. Mistreatment was defined as one positive answer in the Geriatric Mistreatment Scale and frailty was used as a continuum where the greater number of positive criteria according to Fried et al...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165399/greenhouse-gas-emissions-energy-consumption-and-economic-growth-a-panel-cointegration-analysis-for-16-asian-countries
#8
Wen-Cheng Lu
This research investigates the co-movement and causality relationships between greenhouse gas emissions, energy consumption and economic growth for 16 Asian countries over the period 1990-2012. The empirical findings suggest that in the long run, bidirectional Granger causality between energy consumption, GDP and greenhouse gas emissions and between GDP, greenhouse gas emissions and energy consumption is established. A non-linear, quadratic relationship is revealed between greenhouse gas emissions, energy consumption and economic growth, consistent with the environmental Kuznets curve for these 16 Asian countries and a subsample of the Asian new industrial economy...
November 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29165377/a-novel-3d-pedestrian-navigation-method-for-a-multiple-sensors-based-foot-mounted-inertial-system
#9
Wei Yang, Chundi Xiu, Jianmin Zhang, Dongkai Yang
In this paper, we present a novel method for 3D pedestrian navigation of foot-mounted inertial systems by integrating a MEMS-IMU, barometer, and permanent magnet. Zero-velocity update (ZUPT) is a well-known algorithm to eliminate the accumulated error of foot-mounted inertial systems. However, the ZUPT stance phase detector using acceleration and angular rate is threshold-based, which may cause incorrect stance phase estimation in the running gait pattern. A permanent magnet-based ZUPT detector is introduced to solve this problem...
November 22, 2017: Sensors
https://www.readbyqxmd.com/read/29165327/effects-of-dl-3-n-butylphthalide-on-cerebral-ischemia-infarction-in-rat-model-by-mass-spectrometry-imaging
#10
Run-Zhe Liu, Chao-Xin Fan, Zhi-Lin Zhang, Xin Zhao, Yi Sun, Hui-Hui Liu, Zong-Xiu Nie, Xiao-Ping Pu
Dl-3-n-butylphthalide (NBP) is a drug that is used in the treatment of ischaemic stroke. However, to the best of our knowledge, there are no systematic studies investigating the effects of dl-3-n-butylphtalide on the brain metabolism of small molecules. In this study, we first investigated the effects of dl-3-n-butylphthalide on the spatial distribution of small molecules in the brains of rats with permanent middle cerebral artery occlusion (pMCAO) using matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) imaging...
November 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29165323/negative-differential-mobility-and-trapping-in-active-matter-systems
#11
Charles Reichhardt, Cynthia J Olson Reichhardt
Using simulations, we examine the average velocity as a function of applied drift force for active matter particles moving through a random obstacle array. We find that for low drift force, there is an initial flow regime where the mobility increases linearly with drive, while for higher drift forces a regime of negative differential mobility appears in which the velocity decreases with increasing drive due to the trapping of active particles behind obstacles. A fully clogged regime exists at very high drift forces when all the particles are permanently trapped behind obstacles...
November 22, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29164973/an-indirect-treatment-comparison-of-the-efficacy-of-insulin-degludec-liraglutide-ideglira-and-insulin-glargine-lixisenatide-iglarlixi-in-patients-with-type-2-diabetes-uncontrolled-on-basal-insulin
#12
Marc Evans, Liana K Billings, Jonas Håkan-Bloch, Ulla Slothuus, Trine J Abrahamsen, Andreas Andersen, Jeroen P Jansen
AIMS: To obtain estimates of the relative treatment effects between insulin degludec/liraglutide (IDegLira) and insulin glargine U100/lixisenatide (iGlarLixi) in patients with type 2 diabetes mellitus (T2DM) uncontrolled on basal insulin therapy. MATERIALS AND METHODS: Data from phase 3 trials providing evidence for estimating the relative efficacy and safety of IDegLira versus iGlarLixi in patients uncontrolled on basal insulin-only regimens were used in this analysis...
November 22, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29164325/effects-of-recreational-football-on-women-s-fitness-and-health-adaptations-and-mechanisms
#13
REVIEW
Peter Krustrup, Eva Wulff Helge, Peter R Hansen, Per Aagaard, Marie Hagman, Morten B Randers, Maysa de Sousa, Magni Mohr
The review describes the fitness and health effects of recreational football in women aged 18-65 years. The review documents that 2 × 1 h of recreational football training for 12-16 weeks causes marked improvements in maximal oxygen uptake (5-15%) and myocardial function in women. Moreover, mean arterial blood pressure was shown to decrease by 2-5 mmHg in normotensive women and 6-8 mmHg in hypertensive women. This review also show that short-term (< 4 months) and medium-term (4-16 months) recreational football training has major beneficial impact on metabolic health profile in women, with fat losses of 1-3 kg and improvements in blood lipid profile...
November 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29164280/functional-brain-networks-involved-in-decision-making-under-certain-and-uncertain-conditions
#14
Danielle C Farrar, Asim Z Mian, Andrew E Budson, Mark B Moss, Ronald J Killiany
PURPOSE: The aim of this study was to describe imaging markers of decision-making under uncertain conditions in normal individuals, in order to provide baseline activity to compare to impaired decision-making in pathological states. METHODS: In this cross-sectional study, 19 healthy subjects ages 18-35 completed a novel decision-making card-matching task using a Phillips T3 Scanner and a 32-channel head coil. Functional data were collected in six functional runs...
November 21, 2017: Neuroradiology
https://www.readbyqxmd.com/read/29164109/identification-of-directed-interactions-in-kinematic-data-during-running
#15
Giovana Y Nakashima, Theresa H Nakagawa, Ana F Dos Santos, Fábio V Serrão, Michel Bessani, Carlos D Maciel
The knowledge of motion dynamics during running activity is crucial to enhance the development of rehabilitation techniques and injury prevention programs. Recent studies investigated the interaction between joints, using several analysis techniques, as cross-correlation, sensitivity analysis, among others. However, the direction of the joints pairing is still not understood. This paper proposes a study of the influence direction pattern in healthy runners by using kinematic data together with partial directed coherence, a frequency approach of Granger causality...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29163905/laboratory-scale-photoredox-catalysis-using-hydrated-electrons-sustainably-generated-with-a-single-green-laser
#16
Robert Naumann, Christoph Kerzig, Martin Goez
The ruthenium-tris-bipyridyl dication as catalyst combined with the ascorbate dianion as bioavailable sacrificial donor provides the first regenerative source of hydrated electrons for chemical syntheses on millimolar scales. This electron generator is operated simply by illumination with a frequency-doubled Nd:YAG laser (532 nm) running at its normal repetition rate. Much more detailed information than by product studies alone was obtained by photokinetical characterization from submicroseconds (time-resolved laser flash photolysis) up to one hour (preparative photolysis)...
November 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29163829/meta-analysis-of-the-prognostic-value-of-lncrna-zfas1-in-patients-with-solid-tumors
#17
Wei Song, Chuan Tian, Run-Jin Zhang, Shu-Bing Zou, Kai Wang
Expression of ZFAS1, a newly identified long noncoding RNA (lncRNA), is dysregulated in several types of cancer. Here we assessed the prognostic value of ZFAS1 in solid tumors. A comprehensive literature search was performed by screening the PubMed, EMBASE, MEDLINE, Cochrane Library, CNKI, and Wanfang databases. A total of 874 patients from 10 studies were included. The pooled analysis demonstrated that patients with high ZFAS1 expression had a significantly shorter overall survival (OS) (HR, 1.58; 95% CI, 1...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29163473/treadmill-slope-modulates-inflammation-fiber-type-composition-androgen-and-glucocorticoid-receptors-in-the-skeletal-muscle-of-overtrained-mice
#18
Alisson L da Rocha, Bruno C Pereira, Giovana R Teixeira, Ana P Pinto, Fabiani G Frantz, Lucila L K Elias, Fábio S Lira, José R Pauli, Dennys E Cintra, Eduardo R Ropelle, Leandro P de Moura, Rania A Mekary, Ellen C de Freitas, Adelino S R da Silva
Overtraining (OT) may be defined as an imbalance between excessive training and adequate recovery period. Recently, a downhill running-based overtraining (OTR/down) protocol induced the nonfunctional overreaching state, which is defined as a performance decrement that may be associated with psychological and hormonal disruptions and promoted intramuscular and systemic inflammation. To discriminate the eccentric contraction effects on interleukin 1beta (IL-1β), IL-6, IL-10, IL-15, and SOCS-3, we compared the release of these cytokines in OTR/down with other two OT protocols with the same external load (i...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29163307/on-nomological-validity-and-auxiliary-assumptions-the-importance-of-simultaneously-testing-effects-in-social-cognitive-theories-applied-to-health-behavior-and-some-guidelines
#19
Martin S Hagger, Daniel F Gucciardi, Nikos L D Chatzisarantis
Tests of social cognitive theories provide informative data on the factors that relate to health behavior, and the processes and mechanisms involved. In the present article, we contend that tests of social cognitive theories should adhere to the principles of nomological validity, defined as the degree to which predictions in a formal theoretical network are confirmed. We highlight the importance of nomological validity tests to ensure theory predictions can be disconfirmed through observation. We argue that researchers should be explicit on the conditions that lead to theory disconfirmation, and identify any auxiliary assumptions on which theory effects may be conditional...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29163210/a-wearable-test-for-maximum-aerobic-power-real-time-analysis-of-a-60-m-sprint-performance-and-heart-rate-off-kinetics
#20
Jorge L Storniolo, Gaspare Pavei, Alberto E Minetti
Maximum aerobic power ([Formula: see text]) as an indicator of body fitness is today a very well-known concept not just for athletes but also for the layman. Unfortunately, the accurate measurement of that variable has remained a complex and exhaustive laboratory procedure, which makes it inaccessible to many active people. In this paper we propose a quick estimate of it, mainly based on the heart rate off-kinetics immediately after an all-out 60-m sprint run. The design of this test took into account the recent availability of wrist wearable, heart band free, multi-sensor smart devices, which could also inertially detect the different phases of the sprint and check the distance run...
2017: Frontiers in Physiology
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