keyword
https://read.qxmd.com/read/38535026/the-association-between-the-dental-status-and-tongue-thrust-habits-of-latvian-preschool-children-and-their-mothers-oral-health-knowledge
#21
JOURNAL ARTICLE
Lilian Tzivian, Dace Priede, Valdis Folkmanis, Ieva Henkuzena
OBJECTIVES: The aim of this study was to describe the factors that affect the normal dental development of preschool children in Latvia, and to investigate sources that mothers use to get information on children's oral health. MATERIALS AND METHODS: A cross-sectional study was performed in two kindergartens in Latvia (cluster sampling). The study sample comprised 141 child-mother pairs of preschool children aged 4-7 years. The dental situation of all children was assessed including evaluation by an orthodontist and a speech therapist, and mothers of children filled out the survey on oral health-related habits and information about it...
March 12, 2024: Diagnostics
https://read.qxmd.com/read/38534787/unveiling-the-molecular-mechanism-of-trastuzumab-resistance-in-skbr3-and-bt474-cell-lines-for-her2-positive-breast-cancer
#22
JOURNAL ARTICLE
Anna Kokot, Sachin Gadakh, Indrajit Saha, Ewa Gajda, Michał Łaźniewski, Somnath Rakshit, Kaustav Sengupta, Ayatullah Faruk Mollah, Michał Denkiewicz, Katarzyna Górczak, Jürgen Claesen, Tomasz Burzykowski, Dariusz Plewczynski
HER2-positive breast cancer is one of the most prevalent forms of cancer among women worldwide. Generally, the molecular characteristics of this breast cancer include activation of human epidermal growth factor receptor-2 (HER2) and hormone receptor activation. HER2-positive is associated with a higher death rate, which led to the development of a monoclonal antibody called trastuzumab, specifically targeting HER2. The success rate of HER2-positive breast cancer treatment has been increased; however, drug resistance remains a challenge...
March 21, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38534667/antimicrobial-resistance-and-sports-the-scope-of-the-problem-implications-for-athletes-health-and-avenues-for-collaborative-public-health-action
#23
REVIEW
Ognjen Ožegić, Branka Bedenić, Sunčanica Ljubin Sternak, Mario Sviben, Jasminka Talapko, Iva Pažur, Ivana Škrlec, Ivan Segedi, Tomislav Meštrović
Antimicrobial resistance (AMR) poses a global threat, leading to increased mortality and necessitating urgent action-however, its impact on athletes and the world of sports has hitherto been neglected. Sports environments (including athletic and aquatic) exhibit high levels of microbial contamination, potentially contributing to the spread of resistant microorganisms during physical activities. Moreover, the literature suggests that travel for sports events may lead to changes in athletes' gut microbiomes and potentially impact their antibiotic resistance profiles, raising questions about the broader implications for individual and public/global health...
February 29, 2024: Antibiotics
https://read.qxmd.com/read/38534505/biomedical-evaluation-of-early-chronic-kidney-disease-in-the-air-force-building-a-predictive-model-from-the-taiwan-military-health-service
#24
JOURNAL ARTICLE
Po-Jen Hsiao, Ruei-Lin Wang, Fu-Kang Hu, Fu-Ru Tsai, Chih-Chien Chiu, Wen-Fang Chiang, Kun-Lin Wu, Yuan-Kuei Li, Jenq-Shyong Chan, Chi-Ming Chu, Chi-Wen Chang
OBJECTIVE: Chronic kidney disease (CKD) is one of the most common diseases worldwide. The increasing prevalence and incidence of CKD have contributed to the critical problem of high medical costs. Due to stressful environments, aircrew members may have a high risk of renal dysfunction. A better strategy to prevent CKD progression in Air Force personnel would be to diagnosis CKD at an early stage. Since few studies have been conducted in Taiwan to examine the long-term trends in early CKD in Air Force aircrew members, this study is highly important...
February 28, 2024: Bioengineering
https://read.qxmd.com/read/38534499/enhancing-error-detection-on-medical-knowledge-graphs-via-intrinsic-label
#25
JOURNAL ARTICLE
Guangya Yu, Qi Ye, Tong Ruan
The construction of medical knowledge graphs (MKGs) is steadily progressing from manual to automatic methods, which inevitably introduce noise, which could impair the performance of downstream healthcare applications. Existing error detection approaches depend on the topological structure and external labels of entities in MKGs to improve their quality. Nevertheless, due to the cost of manual annotation and imperfect automatic algorithms, precise entity labels in MKGs cannot be readily obtained. To address these issues, we propose an approach named Enhancing error detection on Medical knowledge graphs via intrinsic labEL (EMKGEL)...
February 27, 2024: Bioengineering
https://read.qxmd.com/read/38534289/dental-practice-websites-in-germany-how-do-they-inform-about-fluoridation
#26
JOURNAL ARTICLE
Antje Geiken, Mirja Kock, Lisa Banz, Falk Schwendicke, Christian Graetz
Fluoridation (Fl) is effective in preventing caries; however, it is unclear to what extent its use is counteracted by misinformation on the internet. This study aimed to evaluate the information provided on professional websites of German dental practices regarding fluoridation. A systematic search was performed by two independent examiners, utilizing three search engines, from 10 September 2021 to 11 December 2021. Modified, validated questionnaires (LIDA, DISCERN) were used to evaluate technical and functional aspects, generic quality, and risk of bias...
March 4, 2024: Dentistry Journal
https://read.qxmd.com/read/38534085/lasting-impact-of-the-covid-19-pandemic-on-care-and-prevention-of-sexually-transmitted-infections-in-the-midwest
#27
JOURNAL ARTICLE
Maya Patel, Nicholas Cardoza, Lawrence Weingarten, Nebu Kolenchery, Anne Trolard, Benjamin Cooper, Hilary Reno
BACKGROUND: The COVID-19 pandemic reduced the general accessibility of health services. Many sexually transmitted infection (STI) testing and treatment sites modified services (e.g., reduced hours, limited walk-in availability, decreased testing capacity), changes that may result in permanent change in STI service availability. At the same time, systems were driven to innovate in ways that could benefit patients. This study aimed to describe how the COVID-19 pandemic changed STI clinical services, with a focus on long-term impacts...
April 1, 2024: Sexually Transmitted Diseases
https://read.qxmd.com/read/38534035/adverse-jaw-outcomes-from-immune-checkpoint-inhibitors-for-head-and-neck-cancer-case-reports
#28
JOURNAL ARTICLE
Gayathri Subramanian, Vincent Yeung, Soly Baredes, Sung Kim, Tessa Bergsbaken, Samuel Quek
Radiation treatment plays a mainstream role in the management of head and neck squamous cell carcinomas (HNSCCs). Adverse effects from radiation therapy include osteoradionecrosis of the jaw, and rarely, pathologic fracture. Immune checkpoint inhibitors (ICI) such as pembrolizumab are of growing relevance to the management of metastatic and recurrent HNSCCs. Adverse impacts on bone secondary to medications such as pembrolizumab and nivolumab have been sporadically documented in the literature. The objective of this manuscript is to raise awareness of possible increase in risk for adverse jaw outcomes in patients with HNSCCs exposed to both radiation treatment to the jaws and ICI therapy...
March 27, 2024: Quintessence International
https://read.qxmd.com/read/38533994/mobile-phone-text-messaging-for-medication-adherence-in-secondary-prevention-of-cardiovascular-disease
#29
REVIEW
Julie Redfern, Qiang Tu, Karice Hyun, Matthew A Hollings, Nashid Hafiz, Clara Zwack, Caroline Free, Pablo Perel, Clara K Chow
BACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of death globally, accounting for almost 18 million deaths annually. People with CVDs have a five times greater chance of suffering a recurrent cardiovascular event than people without known CVDs. Although drug interventions have been shown to be cost-effective in reducing the risk of recurrent cardiovascular events, adherence to medication remains suboptimal. As a scalable and cost-effective approach, mobile phone text messaging presents an opportunity to convey health information, deliver electronic reminders, and encourage behaviour change...
March 27, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38533932/temporomandibular-disorders-and-bruxism-up-to-date-assessment-and-screening-tools-the-general-dentist-should-be-aware-of
#30
JOURNAL ARTICLE
Alona Emodi-Perlman, Ilana Eli
The recently proposed shortened screening tools for temporomandibular disorders (TMD) and bruxism should enable a better assessment of these conditions by the general dentist.
March 27, 2024: Dental and Medical Problems
https://read.qxmd.com/read/38533921/editorial-oral-health-luxury-or-a-fundamental-human-right-the-necessity-of-introducing-a-dedicated-oral-health-budget-and-proportionate-universalis-in-greece
#31
JOURNAL ARTICLE
A I Syngelakis, M Tsantidou, Z Tsarnava, C Charalambous
Oral health is an integral part of overall health and critically affects quality of life as well as personal and social well-being. Poor oral health negatively influences general health and creates medical, financial and social burdens for individuals, families and health systems. The US Office of Disease Prevention and Health Promotion (2021) sees use of the oral health care system as a leading health indicator. Oral health improvement is an important step to reduce socioeconomic inequalities and promote the UN Sustainable Development Strategy (Wang et al...
February 29, 2024: Community Dental Health
https://read.qxmd.com/read/38533880/experiences-with-pre-graduate-research-among-danish-medical-students-and-doctors
#32
JOURNAL ARTICLE
Ditte Georgina Zhang, Jawad Ahmad Zahid, Noor Al-Huda Hadi, Simon Francis Thomsen
INTRODUCTION: Pre-graduate research is popular among medical students. Concerns about time constraints and lack of mentorship have been raised in international studies. The extent to which these issues affect Danish medical students remains unclear. We therefore aimed to assess the conditions and outcomes of pre-graduate research among medical students from the University of Copenhagen. METHODS: A descriptive, cross-sectional, questionnaire-based survey on experiences from pre-graduate research was distributed to medical students and recently graduated medical doctors from the University of Copenhagen who had engaged in full-time pre-graduate research...
March 8, 2024: Danish Medical Journal
https://read.qxmd.com/read/38533858/-not-available
#33
JOURNAL ARTICLE
Iben Rix, Ida Marie Heerfordt, Allan Cramer, Henrik Horwitz, Rasmus Huan Olsen
Modern healthcare requires clinicians to navigate through complex drug treatments. This review offers an overview of sources of drug information which can be used for general medication prescription and for challenging patient populations. Key considerations for pregnant or breastfeeding patients, those with renal impairment, and those with liver dysfunction are discussed. We also touch on adverse drug reactions and drug interactions. Finally, information about services from independent regional drug information centers, that can be used by clinicians, are provided...
March 25, 2024: Ugeskrift for Laeger
https://read.qxmd.com/read/38533835/a-meta-analysis-of-electronic-media-use-and-sleep-quality-an-updated-systematic-review
#34
JOURNAL ARTICLE
Xiaoning Han, Enze Zhou, Dong Liu
BACKGROUND: This paper explores the widely discussed relationship between electronic media use and sleep quality, indicating negative effects due to various factors. However, existing meta-analyses on the topic have some limitations. OBJECTIVE: The study aims to analyze and compare the impacts of different digital media types, such as smartphones, online games, and social media, on sleep quality. METHODS: Adhering to PRISMA guidelines, the study performed a systematic meta-analysis of literature across multiple databases, including Web of Science, MEDLINE, PsycINFO, PubMed, Science Direct, Scopus, and Google Scholar, from January 2018 to October 2023...
March 26, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38533739/rozanolixizumab-a-new-therapy-in-the-treatment-of-myasthenia-gravis
#35
REVIEW
Emily M Hitt
OBJECTIVE: The aims of this article are to review the clinical aspects of rozanolixizumab, to describe clinical trial results that led to the drug's approval, and to examine the impact on patient care to aid clinical decision making. DATA SOURCES: A PubMed search was conducted using the terms Rystiggo ™, rozanolixizumab , rozanolixizumab therapy , and myasthenia gravis . The most recent prescribing information was also used for information relating to the drug and for identification of pertinent studies...
March 27, 2024: Annals of Pharmacotherapy
https://read.qxmd.com/read/38533728/the-multifaceted-roles-of-gp-trainers-in-guiding-trainee-transition-to-portfolio-general-practice
#36
JOURNAL ARTICLE
Waseem Jerjes
The journey of transitioning from a GP trainee to a portfolio GP is a complex and transformative process. This article explores the multi-dimensional roles that GP trainers play in guiding trainees through this key transition. This article, also, aims to challenge readers to consider how GP trainers can further enhance their role in minimising barriers and maximising opportunities for trainees, inviting contributions to the educational discussion on this topic.Serving as mentors, GP trainers navigate trainees through the particulars of general practice, ensuring they are equipped with both skills and resilience...
March 27, 2024: Education for Primary Care
https://read.qxmd.com/read/38533427/writing-case-reports-can-improve-seven-components-in-clinical-reasoning
#37
JOURNAL ARTICLE
Toshinori Nishizawa, Kosuke Ishizuka, Yuki Otsuka, Toshiyuki Nakanishi, Akira Kawashima, Taiju Miyagami, Shun Yamashita
Case reports provide scientific knowledge and opportunities for new clinical research. However, it is estimated that less than 5% of cases presented by Japanese generalists at academic conferences are published due to various barriers such as the complex process of writing articles, conducting literature searches, the significant time required, the reluctance to write in English, and the challenge of selecting appropriate journals for publication. Therefore, the purpose of this opinion paper is to provide clinicians with practical tips for writing case reports that promote diagnostic excellence...
2024: International Medical Case Reports Journal
https://read.qxmd.com/read/38533393/medical-and-exercise-consultation-use-for-low-back-and-knee-pain-among-cardiovascular-mass-screening-population-a-cross-sectional-study
#38
JOURNAL ARTICLE
Hiroshige Jinnouchi, Masahiko Kiyama, Akihiko Kitamura, Ko Matsudaira, Hironobu Kakihana, Mina Hayama-Terada, Isao Muraki, Eiko Honda, Takeo Okada, Kazumasa Yamagishi, Hironori Imano, Hiroyasu Iso
Low back and knee pain, as major symptoms and early signs of osteoarthritis, have restricted healthy life expectancy, and numerous guidelines have recommended therapeutic exercise as the first-line treatment for chronic pain. Proportions of medical and exercise consultation use for those pain have been unclear, and these may change in the future. We performed a cross-sectional study of 2,954 persons aged over 30 years in 2017 as a part of the Circulatory Risk in Communities Study. A generalized linear model with logit link and 11-year age-group moving averages were used to estimate sex- and age-specific average proportions of lifetime pain, chronic pain, and dysfunctional chronic pain of the low back and knee, and history of medical and exercise consultation use...
May 2024: Preventive Medicine Reports
https://read.qxmd.com/read/38533388/anaesthetic-records-an-evaluation-of-variation-across-england
#39
R Fenton, C Thompson, S Drake, L Foley, T M Cook
We collected blank non-specialist anaesthetic records from 71 National Health Service Trusts in England. A data set was established by collating all data items found in an initial tranche of 28 records. All 71 records were subsequently analysed for each data item in this data set. We found significant variation: the most populated record included 216 data items and the least included 38 data items: a greater than five-fold variation. There was significant variation in the inclusion of data items commonly considered important to patient safety; 42% of records omitted documentation of fasting status, 72% omitted documentation of a discussion around the risk of accidental awareness during general anaesthesia, 92% omitted documentation of quantitative neuromuscular blockade monitoring and 63% omitted documentation for 'Stop Before You Block' when performing regional anaesthesia...
2024: Anaesthesia reports
https://read.qxmd.com/read/38533309/effects-of-immersive-virtual-nature-on-nature-connectedness-a-systematic-review-and-meta-analysis
#40
REVIEW
Elena Brambilla, Evi Petersen, Karen Stendal, Vibeke Sundling, Tadhg E MacIntyre, Giovanna Calogiuri
OBJECTIVE: This study systematically summarizes the extant literature on the impacts of immersive virtual nature (IVN) on nature connectedness in the general population. METHODS: Papers were considered eligible if peer-reviewed, in English language, comprising experimental or quasi-experimental trials, including at least one outcome relative to nature connectedness in the general population. Database search was conducted on Scopus, Web of Science, Google Scholar, Medline, and GreenFILE (22-28 November 2021)...
2024: Digital Health
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