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General Medical

Simone Kiel, Elisabeth Hey, Annekathrin Haase, Ariane Chaudhuri, Jean-François Chenot
BACKGROUND:  For the correct intake and safe handling of their own medication it is important that patients know about their own medication and can give certain information. This study examines what information patients can provide about their prescribed medication and which factors influence the ability to provide information. METHODS:  A cross-sectional study was conducted. In 10 General Practice, 637 patients (participation rate 57 %) were asked about the name, dosage, frequency of intake and indication of their prescribed medication...
October 2018: Deutsche Medizinische Wochenschrift
Luc Biedermann, Alex Straumann
Eosinophilic esophagitis (EoE) refers to a relatively new chronic inflammatory disease of the esophagus, which according to the current understanding underlies an immune-mediated pathogenesis driven by exposure to allergens. While several open questions remain regarding ethiopathogenesis as well as treatment options and their positioning, one thing has increasingly been recognized. The disease is on the rise and will increasingly be of importance in everyday's clinical practice, not only in expert physicians but also gastroenterologists with a broad clinical spectrum, allergologists and even general practitioners...
October 15, 2018: Current Opinion in Pharmacology
Mehdi Sadeghian, Omid Sadeghi, Ammar Hassanzadeh Keshteli, Hamed Daghaghzadeh, Ahmad Esmaillzadeh, Peyman Adibi
BACKGROUND: Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder worldwide. Physical activity in relation to IBS has been investigated in few studies and data in this regard are conflicting. AIM: To investigate the association between physical activity and IBS in a large sample of Iranian adults. METHODS: This cross-sectional study was done on 4763 Iranian adults in the framework of SEPAHAN (The Study on the Epidemiology of Psycho-Alimentary Health and Nutrition) project...
2018: PloS One
Magnus B Arnli, Theo L Winther, Stian Lydersen, Sverre H Torp
INTRODUCTION: Among clinical challenges regarding human meningiomas is their propensity to recur even in cases with benign histology. Reliable biomarkers that can identify these cases are therefore highly desired. ErbB2/HER2 status is important in the medical management of patients with various human malignancies, whereas its clinical relevance in human meningiomas is ambiguous. For this reason, we wanted to investigate the expression of intra- and extracellular domains of ErbB2/HER2 as well as the level of activated receptor in these tumors...
2018: PloS One
J Smith Torres-Roman, Yuridia Cruz-Avila, Karina Suarez-Osorio, Miguel Ángel Arce-Huamaní, Alejandra Menez-Sanchez, Telmo Raúl Aveiro-Róbalo, Christian R Mejia, Eloy F Ruiz
INTRODUCTION: Motivation in medical students is positively associated with learning strategies. However, the evidence of a direct relationship between motivation and performance is vague. The objective of this study is to determine if the motivation that pushed students to choose the medical career is associated with their academic performance during their university years. METHODS: The study was conducted in 4,290 medical students from 10 countries in Latin America...
2018: PloS One
Chris J James, Chadlia Karoui, Marie-Laurence Laborde, Benoît Lepage, Charles-Édouard Molinier, Marjorie Tartayre, Bernard Escudé, Olivier Deguine, Mathieu Marx, Bernard Fraysse
OBJECTIVE: Normal-hearing subjects listening to acoustic simulations of cochlear implants (CI) can obtain sentence recognition scores near 100% in quiet and in 10 dB signal-to-noise ratio (SNR) noise with acute exposure. However, average sentence recognition scores for real CI listeners are generally lower, even after months of experience, and there is a high degree of heterogeneity. Our aim was to identify the relative importance and strength of factors that prevent CI listeners from achieving early, 1-mo scores as high as those for normal-hearing-listener acoustic simulations...
October 17, 2018: Ear and Hearing
Rachel W Linnemann, Deborah Friedman, Lily L Altstein, Suhayla Islam, Kieu-Tram Bach, Anna M Georgiopoulos, Samuel M Moskowitz, Lael M Yonker
BACKGROUND: Advance care planning (ACP) is recommended for people with cystic fibrosis (CF), yet guidance for optimal implementation is lacking. OBJECTIVE: To assess ACP-related thoughts, comfort level, and preferences among people with CF to guide evidence-based routine implementation of ACP in the CF clinic. DESIGN: A cross-sectional survey assessed ACP-related experiences and preferences. SUBJECTS: Thirty-eight adolescents and adults with CF from an urban CF center...
October 18, 2018: Journal of Palliative Medicine
David Hillebrandt, Anil Gurtoo, Thomas Kupper, Paul Richards, Volker Schöffl, Pankaj Shah, Rianne van der Spek, Nikki Wallis, Jim Milledge
Hillebrandt, David, Anil Gurtoo, Thomas Kupper, Paul Richards, Volker Schöffl, Pankaj Shah, Rianne van der Spek, Nikki Wallis, and Jim Milledge. UIAA Medical Commission recommendations for mountaineers, hillwalkers, trekkers, and rock and ice climbers with diabetes. High Alt Med Biol 00:000-000, 2018.-The object of this advice article is not only to give the diabetic mountaineer general guidance but also to inform his or her medical team of practical aspects of care that may not be standard for nonmountaineers...
October 18, 2018: High Altitude Medicine & Biology
Özgür Öztop Cakmak, Ilker Eren, Ayça Aslanger, Caner Günerbüyük, Hülya Kayserili, Piraye Oflazer, Cüneyt Sar, Mehmet Demirhan, Yasemin Gürsoy Özdemir
Background and purpose: Impaired shoulder function is the most disabling problem for daily life of Fascioscapulohumeral muscular dystrophy (FSHD) patients. Scapulothoracic arthrodesis can give a high impact to the functionality of patients. Here we report our experience with scapulothoracic arthrodesis and spinal stenosis surgery in FSHD patients. Methods: 32 FSHD patients were collected between 2015-2016. Demographical and clinical features were documented. All the patients were neurologically examined...
September 30, 2018: Ideggyógyászati Szemle
E Feck, A A Zulfiqar
The objective of this study was to evaluate frailty by the use of the modified SEGA grid in a population aged 75 years and older. This cross-sectional study was carried out in Marne (Champagne Ardenne), including subjects aged 75 years or more, who can go to medical general practionners consultation. Frailty was assessed by the modified SEGA tool. In total between May 02, 2016 and May 08, 2017, 64 patients were included, aged 80 years ± 3.87, with a majority of women (58 %). The mean frailty score was 6.3 ± 3...
October 2018: Revue Médicale de Liège
Hana Brath, Nishila Mehta, Rachel D Savage, Sudeep S Gill, Wei Wu, Susan E Bronskill, Lynn Zhu, Jerry H Gurwitz, Paula A Rochon
OBJECTIVES: To systematically describe the resources available on preventing, detecting, and reversing prescribing cascades using a scoping review methodology. MEASUREMENTS: We searched Medline, EMBASE, PsychINFO, CINAHL, Cochrane Library, and Sociological Abstracts from inception until July 2017. Other searches (Google Scholar, hand searches) and expert consultations were performed for resources examining how to prevent, detect, or reverse prescribing cascades...
October 18, 2018: Journal of the American Geriatrics Society
Chao-Shun Lin, Chien-Yu Chen, Chun-Chieh Yeh, Chi-Li Chung, Ta-Liang Chen, Chien-Chang Liao
Background: The relationship between chronic obstructive pulmonary disease (COPD) and perioperative outcomes remains incompletely understood. Our purpose is to evaluate the features of postoperative adverse outcomes for geriatric surgical patients with chronic obstructive pulmonary disease (COPD) receiving non-thoracic surgeries. Methods and procedures: We conducted a nationwide study of 15,359 COPD patients aged 65 years and older who received major non-thoracic surgeries in 2008-2013 from the Taiwan National Health Insurance Research Database...
October 18, 2018: QJM: Monthly Journal of the Association of Physicians
Tak Kyu Oh, Jung-Hee Ryu, Hye-Min Sohn, Young-Tae Jeon
BACKGROUND: Although hypothermia is known to have protective effects against ischemic injuries, the effects of hypothermia on kidney injury have not yet been elucidated. Therefore, this study aimed to identify the association between intraoperative hypothermia and postoperative acute kidney injury (AKI) in patients who underwent spine surgery under general anesthesia. METHODS: In this retrospective observational study, we analyzed the medical records of adult patients who underwent elective spine surgery between January 2010 and March 2018...
October 16, 2018: Journal of Neurosurgical Anesthesiology
Christian Schmidt-Kraepelin, Christina Engelke, Kai G Kahl, Joachim Cordes
BACKGROUND: Treatment of schizophrenia with depot medication has advantages compared with oral medication, and among these include an improved compliance. Despite such advantages, prescription rates in many European countries are lower than 20%. The aim of this survey was to study the attitudes toward depot medication among the German general population. To the best of our knowledge, only selective samples have been investigated up until now. METHODS: A representative sample of 754 people were interviewed via telephone by a professional market research and polling organization...
October 16, 2018: Journal of Clinical Psychopharmacology
Melany Lopez, Teresa M Chan, Brent Thoma, Vineet M Arora, N Seth Trueger
PURPOSE: To determine the responsibilities of journal social media editors (SMEs) and describe their goals and barriers and facilitators to their position. METHOD: The authors identified SMEs using an informal listserv and snowball sampling. Participants were interviewed (June-July 2016) about their position, including responsibilities, goals, barriers and facilitators, and attitudes and perceptions about the position. Themes were identified through a thematic analysis and consensus building approach...
October 16, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
Jeremy D Kidd, Curtis Dolezal, Walter O Bockting
PURPOSE: Transgender individuals smoke tobacco at disproportionately higher rates than the general U.S. population, and concurrent use of gender-affirming hormones (estrogen or testosterone) and tobacco confers greater cardiovascular (CV) risk. This study examines the relationship between tobacco use and legal document gender-marker change, and medical/surgical interventions for gender transition. METHODS: Data came from an Internet-based survey of U.S. trans-feminine (n = 631) and trans-masculine (n = 473) individuals...
October 2018: LGBT Health
Nicole A Carreau, Anna C Pavlick
As recently as 10 years ago, a diagnosis of metastatic melanoma was considered fatal, with a prognosis of typically 6 months or less from diagnosis. The development of checkpoint inhibitors, such as ipilimumab and nivolumab, which modulate the effects of the CTLA-4 and PD-1, respectively, has revolutionized outcomes for these patients. Monotherapy improves metastatic disease survival, but dual therapy provides greater benefit with 58% of patients alive at 3 years. Combination immunotherapy is even active in brain metastases...
October 18, 2018: Future Oncology
Kathleen N Fenton, Marcelo Cardarelli, Frank Molloy, William M Novick
BACKGROUND: In countries with ample resources, no debate exists as to whether heart surgery should be provided. However, where funding is limited, what responsibility exists to care for children with congenital heart defects? If children have a "right" to surgical treatment, to whom is the "duty" to provide it assigned? These questions are subjected to ethical analysis. METHODS: Examination is initially based on the four principles of medical ethics: autonomy, beneficence, non-maleficence, and justice...
October 18, 2018: Cardiology in the Young
Anna Klaudia Bollmann, Balázs Fábián, Judit Molnár
INTRODUCTION: The diagnosis of cancer elicits greater distress than any other diagnosis. The prevalence of psychological difficulties is high in cancer, and resources of the medical staff are limited. The development of efficient screening measures is therefore of utmost importance. Sleep is vital to all psychological functioning and poor sleep is a known problem in cancer. AIM: The main goal of the present study was testing of visual analogue scales assessing sleep quality and fatigue...
October 2018: Orvosi Hetilap
K Simon Yeung LAc, Jyothirmai Gubili, Jun J Mao
Herbs have served as medicine throughout human history. Since the passage of the Dietary Supplement Health and Education Act (DSHEA), inconsistent regulatory practices have resulted in widespread, indiscriminate use of herbal supplements. Available data indicate that cancer patients use these products (along with standard treatments) more often than the general population. The reasons cited for such use include improving health, reducing the risk of recurrence, and reducing the side effects of cancer treatments...
October 17, 2018: Oncology (Williston Park, NY)
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