Lydia Coxon, Jan Vollert, Danielle Perro, Claire E Lunde, Joana Ferreira-Gomes, Ana Charrua, Pedro Abreu-Mendes, Michal Krassowski, Judy Birch, Jane Meijlink, Lone Hummelshoj, Anja Hoffmann, Qasim Aziz, Lars Arendt-Nielsen, Esther Pogatzki-Zahn, Emma Evans, Lysia Demetriou, Stephen B McMahon, Stacey A Missmer, Christian M Becker, Krina T Zondervan, Andrew W Horne, Francisco Cruz, Christine B Sieberg, Rolf-Detlef Treede, Jens Nagel, Katy Vincent
Chronic pelvic pain (CPP), despite its high prevalence, is still relatively poorly understood mechanistically. This study, as part of the Translational Research in Pelvic Pain (TRiPP) project, has used a full quantitative sensory testing (QST) paradigm to profile n = 85 women with and without CPP (endometriosis or bladder pain specifically). We used the foot as a control site and abdomen as the test site. Across 5 diagnostically determined subgroups, we found features which are common across different aetiologies, eg, gain of function in pressure pain threshold (PPT) when assessing responses from the lower abdomen or pelvis (referred pain site)...
June 7, 2023: Pain