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https://www.readbyqxmd.com/read/30517258/use-of-3d-printing-in-preoperative-planning-and-training-for-aortic-endovascular-repair-and-aortic-valve-disease
#1
Eduardo Nascimento Gomes, Ricardo Ribeiro Dias, Bruno Aragão Rocha, José Augusto Duncan Santiago, Fabrício José de Souza Dinato, Eduardo Keller Saadi, Walter J Gomes, Fabio B Jatene
INTRODUCTION: Three-dimensional (3D) printing has become an affordable tool for assisting heart surgeons in the aorta endovascular field, both in surgical planning, education and training of residents and students. This technique permits the construction of physical prototypes from conventional medical images by converting the anatomical information into computer aided design (CAD) files. OBJECTIVE: To present the 3D printing feature on developing prototypes leading to improved aortic endovascular surgical planning, as well as transcatheter aortic valve implantation, and mainly enabling training of the surgical procedure to be performed on patient's specific condition...
September 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/30515734/relationship-between-serum-sclerostin-vascular-sclerostin-expression-and-vascular-calcification-assessed-by-different-methods-in-esrd-patients-eligible-for-renal-transplantation-a-cross-sectional-study
#2
Min Li, Hua Zhou, Min Yang, Changying Xing
PURPOSE: Vascular calcification (VC) is known to be prevalent in patients with end-stage renal disease (ESRD). Sclerostin has been identified to be involved in the cross-talk between the kidney, vasculature, and bone. The aims of the present study were to evaluate vessel sclerostin expression and its correlation with VC, as well as serum sclerostin levels. METHODS: A total of 51 adult ESRD patients undergoing living donor renal transplant (RT) were enrolled in this study...
December 4, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/30513758/evaluation-of-68-ga-ga-dota-tctp-1-for-the-detection-of-metalloproteinase-2-9-expression-in-mouse-atherosclerotic-plaques
#3
Max Kiugel, Sanna Hellberg, Meeri Käkelä, Heidi Liljenbäck, Tiina Saanijoki, Xiang-Guo Li, Johanna Tuomela, Juhani Knuuti, Antti Saraste, Anne Roivainen
Background : The expression of matrix metalloproteinases 2/9 (MMP-2/9) has been implicated in arterial remodeling and inflammation in atherosclerosis. We evaluated a gallium-68 labeled peptide for the detection of MMP-2/9 in atherosclerotic mouse aorta. Methods : We studied sixteen low-density lipoprotein receptor deficient mice (LDLR-/- ApoB100/100 ) kept on a Western-type diet. Distribution of intravenously-injected MMP-2/9-targeting peptide, [68 Ga]Ga-DOTA-TCTP-1, was studied by combined positron emission tomography (PET) and contrast-enhanced computed tomography (CT)...
December 1, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/30508179/association-of-progressive-thoracic-aortic-calcification-with-future-cardiovascular-events-and-all-cause-mortality-ability-to-improve-risk-prediction-results-of-the-heinz-nixdorf-recall-hnr-study
#4
Hagen Kälsch, Amir A Mahabadi, Susanne Moebus, Nico Reinsch, Thomas Budde, Barbara Hoffmann, Andreas Stang, Karl-Heinz Jöckel, Raimund Erbel, Nils Lehmann
Aims: Thoracic aortic calcification (TAC) is measured by computed tomography (CT). We investigated the association of TAC-progression with incident cardiovascular (CV) events and all-cause mortality in a population-based cohort and to determine its predictive value for these endpoints. Methods and results: In 3080 participants (45-74 years, 53.6% women), risk factors and TAC via CT were measured at baseline and at a second examination after 5.1 ± 0.3 years...
December 1, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/30507309/value-of-ct-spectral-imaging-in-the-differential-diagnosis-of-thymoma-and-mediastinal-lymphoma
#5
Yijing Xie, Shipeng Zhang, Jianli Liu, Xiaohong Liang, Xueling Zhang, Yuting Zhang, Zhuoli Zhang, Junlin Zhou
OBJECTIVE: To investigate the imaging characteristics of thymoma and mediastinal lymphoma using spectral CT and evaluate whether the quantitative information can improve the differential diagnosis of these diseases. METHODS: This retrospective study was approved by the institutional review board, and written informed consent was obtained from all patients. Overall, 39 patients with mediastinal tumors (24 thymomas and 15 mediastinal lymphomas) were examined with CT spectral imaging during the arterial phase (AP) and venous phase (VP)...
December 3, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/30504863/improved-enhancement-in-ct-angiography-with-reduced-contrast-media-iodine-concentrations-at-constant-iodine-dose
#6
Toon Van Cauteren, Gert Van Gompel, Koenraad H Nieboer, Inneke Willekens, Paul Evans, Sven Macholl, Steven Droogmans, Johan de Mey, Nico Buls
The study objective is to investigate the impact of a wide range of contrast media (CM) iodine concentrations on CT enhancement at constant total iodine dose (TID) and iodine delivery rate (IDR). Seven injection protocols, based on different iodine concentrations ranging from 120 to 370 mg I/mL, were assessed on 4 minipigs at a constant TID of 320 mg I/kg and IDR of 0.64 g I/s. Dynamic images were acquired on a clinical 64-slice MDCT scanner for 120 s with the abdominal aorta, vena cava inferior and liver parenchyma in the field-of-view...
November 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30503911/long-term-results-after-open-repair-of-inflammatory-infrarenal-aortic-aneurysms
#7
Carola M Wieker, Philipp von Stein, Claudio Bianchini Massoni, Fabian Rengier, Dittmar Böckler, Philipp Geisbüsch
OBJECTIVE: The objective of this study was to investigate the long-term outcome after open repair of inflammatory infrarenal aortic aneurysms. METHODS: A total of 62 patients (mean age, 68.9 ± 8.8 years; 91.9% male) undergoing open surgery for inflammatory aortic aneurysm from 1995 until 2014 in a high-volume vascular center were retrospectively evaluated. The patients' demographics, preoperative and postoperative clinical characteristics, imaging measurements, and procedural data were collected...
June 28, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/30500658/successful-endovascular-treatment-of-a-ruptured-type-i-thoracoabdominal-aneurysm%C3%A2-twice
#8
Joel Sousa, Ana-Teresa Vilares, Armando Mansilha
INTRODUCTION: Only a minority of vascular surgeons have personal experience on thoracoabdominal aneurysm (TAA) repair, and even less have performed surgery on these formidable lesions for rupture. Unsurprisingly, when open surgery was the only treatment option available, these impressive pathologies were frequently deemed inoperable and managed conservatively. Endovascular techniques brought new hope in these scenarios, but despite current advances, morbidity and mortality remains high, even in experienced centres...
November 27, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30500648/treatment-of-complex-aortic-aneurysms-using-combination-of-renal-and-visceral-bypass-and-fenestrated-branched-stent-grafts
#9
Ambroise Duprey, Sabrina Ben Ahmed, Nellie Della Schiava, Patrick Feugier, Eugenio Rosset, Jean-Pierre Favre, Bertrand Chavent, Jean-Noël Albertini
PURPOSE: The purpose of this study was to report our experience of treatment of aortic aneurysms using combination of renal and visceral arteries bypass and fenestrated/branched stentgraft in various complex anatomical situations. METHODS: Between November 2005 and March 2017, 10 patients underwent a hybrid strategy combining bypasses for renal and/or visceral arteries and custom-made fenestrated/branched stent-grafts. Two patients had abdominal aortic aneurysm (1 juxtarenal and 1 suprarenal) and 8 patients had thoracoabdominal aortic aneurysm (1 type I, 2 type II including one dissection, 2 type III, 1 type IV and 2 type V)...
November 27, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30496898/retroperitoneal-liposarcoma-masquerading-as-an-impending-rupture-of-inflammatory-abdominal-aortic-aneurysm
#10
Christos D Karkos, Panagiotis D Pepis, Marios Theologou, Konstantinos Ballas, Panagiotis Petras, Stergios Arapoglou, Ioakeim T Giagtzidis, Maria Mitka, Ioannis Pliatsios, Konstantinos O Papazoglou, Apostolos G Kambaroudis
BACKGROUND: We present a unique case scenario of a periaortic liposarcoma masquerading as an impending rupture of an inflammatory abdominal aortic aneurysm (AAA). CASE REPORT: A 57-year-old man was referred to our unit for an emergency endovascular repair of "an inflammatory AAA with CT features of impending rupture". He underwent an uneventful endovascular repair with a bifurcated endograft (C3, Gore, Flagstaff, AZ, USA). Seven weeks later, CT showed that the periaortic "mass" grew larger and asymmetric and a CT-guided needle biopsy suggested the presence of a high grade malignant mesenchymal tumor...
November 26, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30484359/stent-frame-movement-following-endovascular-aneurysm-sealing-in-the-abdominal-aorta
#11
Asma Yafawi, Richard G McWilliams, Robert K Fisher, Andrew England, Maria Karouki, Francesco Torella
PURPOSE: To investigate the incidence and extent of stent frame movement after endovascular aneurysm sealing (EVAS) in the abdominal aorta and its relationships to aneurysm growth and the instructions for use (IFU) of the Nellix endograft. METHODS: A retrospective single-center study was conducted to review the clinical data and computed tomography (CT) images of 75 patients (mean age 76±7.6 years; 57 men) who underwent infrarenal EVAS and had a minimum 1-year follow-up...
November 28, 2018: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/30483815/sex-specific-aortic-root-anatomy-in-patients-with-bicuspid-aortic-valve-undergoing-tavr-in-a-chinese-cohort
#12
F Du, X Liu, Q Zhu, Y He, J Jiang, T Napawan, S Jaiswal, Z Chen, J Wang
OBJECTIVES: The aim of this study is to investigate the sex-specific aortic root anatomy in patients with bicuspid aortic valve (BAV). PATIENTS AND METHODS: This retrospective study includes 73 consecutive patients with BAV who underwent CT evaluation before transcatheter aortic valve replacement (TAVR) between July 2013 and April 2017 in the Second Affiliated Hospital of Zhejiang University. RESULT: The size of the annulus, diameter and height of the sinotubular junction (STJ), height of the coronary artery ostia, and dimension of the aorta were measured...
November 27, 2018: Herz
https://www.readbyqxmd.com/read/30483678/air-embolism-into-superior-mesenteric-artery-following-replacement-of-ascending-aorta-for-aortic-dissection-a-rare-and-fatal-case
#13
Lukas Lambert, Tomas Grus, Rudolf Spunda, Martin Balik, Stanislav Trca
We report an unusual case of fatal air embolism into the superior mesenteric artery in a patient, who underwent replacement of the ascending aorta for aortic dissection type A. CT performed twice on the first postoperative day showed abundant air in the superior mesenteric artery and its branches (but not in the portal-venous system) indicating air embolism with no signs of bowel necrosis. On the second postoperative day, the patient underwent extensive bowel resection due to bowel ischemia and died on the third postoperative day on MODS/SIRS...
October 18, 2018: Journal of the Belgian Society of Radiology
https://www.readbyqxmd.com/read/30480591/detection-of-calcified-aortic-plaques-in-an-apolipoprotein-e-animal-model-using-a-human-computed-tomography-system-for-ultra-high-resolution-imaging-a-feasibility-study
#14
Calin Manta, Mathias Meyer, Cyrill Géraud, Mareike Roscher, Sergij Goerdt, Stefan O Schoenberg, Thomas Henzler, Melissa M Ong
PURPOSE: The purpose of this study was to prospectively evaluate the feasibility of detecting calcified aortic plaques in apolipoprotein E knockout (ApoE-KO) mice using a state-of-the-art human computed tomography (CT) system. MATERIALS AND METHODS: Eleven ApoE-KO and 9 wild-type mice, all male, were examined in this study. After intraperitoneal injection of 6.6% ketamine all mice underwent 2 ultra-high-resolution CT protocols on a third-generation dual-source CT system at 120 kVp and 130 kVp tube voltage, both performed with a tube current time product of 1300 mAs...
November 21, 2018: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/30478160/sudden-onset-of-lower-limb-flaccid-paralysis
#15
Francesca Seregni, Saraswathy Sabanathan, Justin Cross, Manali Chitre, Deepa Krishnakumar
A previously well 15-year-old boy presented to the emergency department with sudden-onset severe back pain and inability to weight bear. Preceding this event, he stretched out in bed and felt a click in his back.On examination, he was alert and interactive with normal vital signs. Neurological examination of the lower limbs demonstrated bilateral hypotonia and reduced power to 2/5 proximally and distally, absent reflexes, sensory level at L2 with paraesthesia (pins and needles) and dysaesthesia bilaterally...
November 26, 2018: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/30476605/diagnosis-and-treatment-of-aortic-saddle-embolism
#16
Xiangjiu Ding, Yang Liu, Qingbo Su, Sanyuan Hu, Jianjun Jiang
OBJECTIVE: Acute aortic occlusion is a rare but life-threatening medical condition that can result from aortic saddle embolism, thrombosis of an atherosclerotic aorta, or aortic dissection. Herein are described the diagnostic and therapeutic characteristics for a series of patients with aortic saddle embolism. METHODS: A retrospective review of medical records was performed for patients receiving treatment for aortic saddle embolism at a university hospital in China between January 2001 and September 2017...
November 23, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30476601/surveillance-recommendations-following-tevar-should-be-based-on-initial-indication-for-repair
#17
Richard A Meena, Jaime Benarroch-Gampel, Bradley G Leshnower, Guillermo A Escobar, Yazan Duwayri, William D Jordan, Ravi R Rajani
INTRODUCTION: Current surveillance recommendations following thoracic endovascular aortic repair (TEVAR) include contrast-enhanced CT scans at one-, two-, six-, and 12-month intervals, with annual scans thereafter. Patient compliance with such schedules remains inconsistent for all etiologies of aortic disease. It remains unclear which boundaries prevent compliance and whether compliance is associated with improved aorta-specific outcomes. METHODS: A retrospective analysis was performed of a multicenter healthcare system's electronic medical records to include all patients who underwent TEVAR from 7/1/2011 to 4/1/2016...
November 23, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30475441/electrocardiography-gated-cardiac-ct-angiography-can-differentiate-brachycephalic-dogs-with-and-without-pulmonary-valve-stenosis-and-findings-differ-from-transthoracic-echocardiography
#18
Ada To, Eric T Hostnik, Jaylyn D Rhinehart, Brian A Scansen
Pulmonary valve stenosis (PS) is one of the most commonly diagnosed congenital heart defects in dogs. Currently, transthoracic echocardiography (TTE) is the standard modality used to evaluate PS. Image acquisition by TTE can be challenging in some brachycephalic breeds of dogs. The use of echocardiographic-gated CT angiography (ECG-gated CTA) in veterinary medicine is limited. This retrospective method comparison study investigated right and left ventricular outflow diameters by sedated ECG-gated CTA and unsedated TTE in 14 brachycephalic dogs with PS and 12 brachycephalic dogs without PS...
November 26, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/30475346/does-the-severity-of-the-curve-in-lenke-1-and-2-adolescent-idiopathic-scoliosis-patients-affect-the-distance-and-position-of-the-aorta-from-vertebra
#19
Chee Kidd Chiu, Keong Joo Lee, Weng Hong Chung, Josephine Rebecca Chandren, Chris Yin Wei Chan, Mun Keong Kwan
STUDY DESIGN: Retrospective study of a prospectively-collected data. OBJECTIVE: To determine whether the severity of the curve magnitude in Lenke 1 and 2 adolescent idiopathic scoliosis (AIS) patients affects the distance and position of the aorta from the vertebra. SUMMARY OF BACKGROUND DATA: There were studies that looked into the position of the aorta in scoliotic patients but none of them documented the change in distance of the aorta to the vertebra in relation to the magnitude of the scoliosis...
November 20, 2018: Spine
https://www.readbyqxmd.com/read/30470857/an-association-study-in-ptpn22-suggests-that-is-a-risk-factor-to-takayasu-s-arteritis
#20
María Elena Soto, Isela Montufar-Robles, Silvia Jiménez-Morales, Ricardo Gamboa, Claudia Huesca-Gómez, Julian Ramírez-Bello
OBJECTIVES: Takayasu's arteritis (TA) represents a rare autoimmune disease (AD) characterized by systemic vasculitis that primarily affects large arteries, especially the aorta and the aortic arch and its main branches. Genetic components in TA are largely unknown. PTPN22 is a susceptibility loci for different ADs; however, the role of different PTPN22 single-nucleotide polymorphisms (SNPs) in the susceptibility to TA is not clear. METHODS: We evaluated the PTPN22 R620W (C1858T), R263Q (G788A), and - 123G/C SNPs in a group of patients with TA and in healthy individuals from Mexico...
November 23, 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
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