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https://www.readbyqxmd.com/read/30321670/surgical-treatment-of-endometriosis-excision-versus-ablation-of-peritoneal-disease
#1
EDITORIAL
Tommaso Falcone, Jeffrey R Wilson
No abstract text is available yet for this article.
October 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/30319054/assessment-of-the-clinicopathological-relevance-of-mesothelin-level-in-plasma-peritoneal-fluid-and-tumor-tissue-of-epithelial-ovarian-cancer-patients
#2
Karolina Okła, Justyna Surówka, Karolina Frąszczak, Arkadiusz Czerwonka, Katarzyna Kaławaj, Anna Wawruszak, Jan Kotarski, Iwona Wertel
Ovarian cancer remains the most lethal gynecologic malignancy. This is due to lack of effective screening, diagnosis predominance in late stage of disease, a high recurrence rate after primary therapy, and poor treatment response in platinum-resistant tumor. Thus, unique biomarkers, predictive of individual disease course, and prognosis are urgently needed. The aim of our study was to assess the clinicopathological significance of plasma, peritoneal fluid, and tumor tissue levels of mesothelin in epithelial ovarian cancer patients...
October 2018: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/30318980/high-mortality-in-peritonitis-due-to-mycobacterium-avium-complex-retrospective-study-and-systematic-literature-review
#3
Aurélie Baldolli, Claire Daurel, Renaud Verdon, Arnaud de La Blanchardière
BACKGROUND: Mycobacterium avium complex (MAC) infection is often disseminated and mainly involves lymph nodes, spleen, liver or bone marrow. Peritonitis due to MAC infection (PMAC) is a very uncommon manifestation. METHODS: In this report, after describing the case of the only PMAC infection in our 10-year retrospective study, which occurred in an AIDS patient who was non-adherent to highly active antiretroviral therapy (HAART), we performed a systematic literature review of documented bacteriological PMAC...
October 14, 2018: Infectious Diseases
https://www.readbyqxmd.com/read/30318504/case-of-serotonin-syndrome-initially-presenting-as-diffuse-body-pain
#4
Michael H Guo, Reesa L Monir, Ashleigh Wright, Neal P Holland
BACKGROUND Serotonin syndrome is a common yet potentially life-threatening condition caused by increased serotonergic activity, usually from serotonergic pharmaceutical agents. Primary features of serotonin syndrome include mental status changes, autonomic hyperactivity, and neuromuscular abnormalities. However, the presentation of serotonin syndrome is often quite variable, leading to its under-diagnosis. CASE REPORT A 50-year-old female with chronic kidney disease on peritoneal dialysis presented to the Emergency Department with severe, diffuse body pain...
October 15, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/30318356/role-of-vitamin-d-deficiency-as-a-risk-factor-for-infections-in-cirrhotic-patients
#5
Haidi K Ramadan, Nahed A Makhlouf, Amal A Mahmoud, Mohamed Abd Elrhman, Muhammad Abbas El-Masry
BACKGROUND: Vitamin D plays a role in innate and acquired immunity. The risk for bacterial infections is increased in cirrhotic patients due to low levels of vitamin D. This study aimed to determine serum 25-(OH) vitamin D levels among cirrhotic patients in the presence and absence of infections and correlate this level with liver disease severity. METHODS: This cross-sectional analytic study recruited 87 hospitalised cirrhotic patients who were divided into the following groups: group with evidence of infection (45 cases) and group without infection (42 cases)...
October 11, 2018: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/30316723/comparison-of-outcomes-in-early-stage-uterine-clear-cell-carcinoma-and-serous-carcinoma
#6
Minsi Zhang, T Jonathan Yang, Neil B Desai, Deborah DeLair, Marisa A Kollmeier, Vicky Makker, Mario M Leitao, Nadeem R Abu-Rustum, Kaled M Alektiar
PURPOSE: The treatment paradigm for uterine clear cell carcinoma is often linked to serous carcinoma. This study compares oncologic outcomes between women with uterine clear cell and serous carcinoma. METHODS AND MATERIALS: We reviewed 114 women with stage I-II uterine clear cell carcinoma (n = 17, 15%) or serous carcinoma (n = 97, 85%) who underwent hysterectomy and salpingo-oophorectomy at our institution from April 1992 to December 2011; 86 (76%) had stage IA, 14 (12%) had stage IB, and 14 (12%) had stage II disease...
October 10, 2018: Brachytherapy
https://www.readbyqxmd.com/read/30316441/oligo-anovulation-is-not-a-rarer-feature-in-women-with-documented-endometriosis
#7
Pietro Santulli, Chloe Tran, Vanessa Gayet, Mathilde Bourdon, Chloe Maignien, Louis Marcellin, Khaled Pocate-Cheriet, Charles Chapron, Dominique de Ziegler
OBJECTIVE: To study the prevalence of oligo-anovulation in women suffering from endometriosis compared to that of women without endometriosis. DESIGN: A single-center, cross-sectional study. SETTING: University hospital-based research center. PATIENT (S): We included 354 women with histologically proven endometriosis and 474 women in whom endometriosis was surgically ruled out between 2004 and 2016. INTERVENTION: None...
October 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/30315556/subdural-hemorrhage-in-patients-with-end-stage-renal-disease-requiring-dialysis-a-single-center-study
#8
Cheng-Yang Hsieh, Chia-Cheng Lai, Jung-Shun Lee, Chin-Chung Tseng
PURPOSE: Patients with end-stage renal disease (ESRD) have higher risks of subdural hemorrhage (SDH) and subsequent 30-day mortality. However, evidences regarding optimal mode of dialysis therapy during acute management are sparse. We aimed to compare the outcomes of ESRD patients who received continuous peritoneal dialysis (CPD) or extended hemodialysis (EHD) after SDH and determined factors associated with 30-day mortality. METHODS: We retrospectively reviewed consecutive patients with SDH and ESRD in a medical center...
March 15, 2018: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/30315283/on-treatment-improvement-of-meld-score-reduces-death-and-hepatic-events-in-patients-with-hepatitis-b-related-cirrhosis
#9
Terry Cheuk-Fung Yip, Henry Lik-Yuen Chan, Yee-Kit Tse, Kelvin Long-Yan Lam, Grace Chung-Yan Lui, Vincent Wai-Sun Wong, Grace Lai-Hung Wong
OBJECTIVES: Antiviral treatment modifies the natural history of chronic hepatitis B (CHB)-related cirrhosis as reflected by improving Model for End-Stage Liver Disease (MELD) score over time. We evaluated the impact of on-treatment change of MELD score on clinical outcomes in patients with CHB-related cirrhosis. METHODS: Cirrhotic CHB patients who received entecavir and/or tenofovir disoproxil fumarate for at least 6 months in Hong Kong between 2005 and 2016 were identified...
October 12, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/30315153/poh1-deubiquitinates-pro-interleukin-1%C3%AE-and-restricts-inflammasome-activity
#10
Li Zhang, Yun Liu, Boshi Wang, Guiqin Xu, Zhaojuan Yang, Ming Tang, Aihui Ma, Tiantian Jing, Xiaoli Xu, Xiaoren Zhang, Yongzhong Liu
Inflammasome activation is essential for host defence against invading pathogens, but is also involved in various forms of inflammatory diseases. The processes that control inflammasome activity are thus important for averting excessive immune responses and tissue damage. Here we show that the deubiquitinase POH1 negatively regulates the immune response triggered by inflammasome activation. POH1 deficiency in macrophages enhances mature IL-1β production without significant alterations in inflammasome priming and ASC-caspase-1 activation...
October 12, 2018: Nature Communications
https://www.readbyqxmd.com/read/30315042/the-effect-of-automated-versus-continuous-ambulatory-peritoneal-dialysis-on-mortality-risk-in-china
#11
Xuemei Li, Hong Xu, Nan Chen, Zhaohui Ni, Meng-Hua Chen, Limeng Chen, Jie Dong, Wei Fang, Yusheng Yu, Xiao Yang, Jiang-Hua Chen, Xue-Qing Yu, Qiang Yao, James A Sloand, Mark Marshall
BACKGROUND: There is an emerging practice pattern of automated peritoneal dialysis (APD) in China. We report on outcomes compared to continuous ambulatory peritoneal dialysis (CAPD) in a Chinese cohort. METHODS: Data were sourced from the Baxter Healthcare (China) Investment Co. Ltd Patient Support Program database, comprising an inception cohort commencing PD between 1 January 2005 and 13 August 2015. We used time-dependent cause-specific Cox proportional hazards and Fine-Gray competing risks (kidney transplantation, change to hemodialysis) models to estimate relative mortality risk between APD and CAPD...
October 12, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/30315041/center-specific-risk-adjusted-standardized-mortality-rates-on-continuous-ambulatory-peritoneal-dialysis-in-china
#12
Xue-Qing Yu, Meng-Hua Chen, Jie Dong, Hong Liu, Zhang-Suo Liu, Qiang Yao, James A Sloand, Mark Marshall
BACKGROUND: The aim of this study was to determine if there were centers in China with unusually high levels of risk-adjusted mortality in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS: We analyzed an inception cohort commencing CAPD between 1 January 2005 and 13 August 2015, followed until death, dropout defined as discontinuation of Baxter products, loss to follow-up, or 13 November 2015, whichever occurred first. We calculated standardized mortality ratios (SMRs) from Cox proportional hazards models, adjusting for age, gender, employment status, insurance status, primary renal disease, size of peritoneal dialysis (PD) program, and year of dialysis inception...
October 12, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/30315040/number-of-daily-peritoneal-dialysis-exchanges-and-mortality-risk-in-a-chinese-population
#13
Xue-Qing Yu, Jiang-Hua Chen, Zhaohui Ni, Nan Chen, Meng-Hua Chen, Jie Dong, Limeng Chen, Yusheng Yu, Xiao Yang, Wei Fang, Qiang Yao, James A Sloand, Mark Marshall
BACKGROUND: We report outcomes on ≥ 4 compared with < 4 exchanges/day in a Chinese cohort on continuous ambulatory peritoneal dialysis (CAPD). METHODS: Data were sourced from the Baxter (China) Investment Co. Ltd Patient Support Program database, comprising an inception cohort commencing CAPD between 1 January 2005 and 13 August 2015. We used cause-specific Cox proportional hazards and Fine-Gray competing risks (kidney transplantation, change to hemodialysis) models to estimate mortality risk on ≥ 4 compared with < 4 exchanges/day...
October 12, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/30314341/association-between-end-stage-renal-disease-and-incident-diabetes-mellitus-a-nationwide-population-based-cohort-study
#14
Pin-Pin Wu, Chew-Teng Kor, Ming-Chia Hsieh, Yao-Peng Hsieh
BACKGROUND: Glucose is one of the constituents in hemodialysates and peritoneal dialysates. How the dialysis associates with the incident diabetes mellitus (DM) remains to be assessed. METHODS: The claim data of end-stage renal disease (ESRD) patients who initiated dialysis from and a cohort of matched non-dialysis individuals from 2000 to 2013 were retrieved from the Taiwan National Health Insurance Research Database to examine the risk of incident DM among patients on hemodialysis (HD) and peritoneal dialysis (PD)...
October 11, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/30310803/significance-of-lymph-node-metastasis-in-the-survival-of-stage-iv-colorectal-cancer-by-hematogenous-metastasis
#15
Eon Chul Han, Yoon-Hye Kwon, Kyu Joo Park, Seung-Yong Jeong, Sung-Bum Kang, Jae Hwan Oh, Seung Chul Heo
Purpose: Although lymph node (LN) metastasis is an important prognostic marker of colorectal cancer (CRC), the effect of LN metastasis on the survival of stage IV CRC is debated yet. Methods: LN status and survivals as well as clinicopathological features of synchronous stage IV CRC patients, operated for 8 years, were analyzed. Patients with hematogenous metastases were included only but those with peritoneal seeding or preoperative adjuvant therapy were not included...
October 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/30309721/a-phase-ii-evaluation-of-elesclomol-sodium-and-weekly-paclitaxel-in-the-treatment-of-recurrent-or-persistent-platinum-resistant-ovarian-fallopian-tube-or-primary-peritoneal-cancer-an-nrg-oncology-gynecologic-oncology-group-study
#16
Bradley J Monk, James T Kauderer, Katherine M Moxley, Albert J Bonebrake, Summer B Dewdney, Angeles Alvarez Secord, Frederick R Ueland, Carolyn M Johnston, Carol Aghajanian
OBJECTIVE: Preclinical data suggest elesclomol increases oxidative stress and enhances sensitivity to cytotoxic agents. The objective of this prospective multicenter phase 2 trial was to estimate the activity of IV elesclomol plus weekly paclitaxel in patients with platinum-resistant recurrent ovarian, tubal or peritoneal cancer through the frequency of objective tumor responses (ORR). METHODS: Patients with measurable disease, acceptable organ function, performance status ≤ 2, and one prior platinum containing regimen were eligible...
October 8, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/30306769/surgical-treatment-of-acute-complicated-diverticulitis-in-the-elderly
#17
Roberto Cirocchi, Riccardo Nascimbeni, Gian Andrea Binda, Nereo Vettoretto, Rosario Cuomo, Giovanni Gambassi, Antonio Amato, Bruno Annibale
INTRODUCTION: Although the true prevalence is unknown, colonic diverticulosis is one of the most common disease of the digestive tract in Western countries. Based on administrative data of hospitalized patients, the incidence of diverticulitis has been increasing in last decades. In general, elderly patients undergo less frequently an elective colonic resection; but a substantial part of emergency surgeries is performed in elderly patients. In these older patients the choice of any clinical and surgical option is to be correlated not only to the severity of diverticulitis, but also to general status and the co-existing comorbidities...
October 9, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/30305914/severe-acute-kidney-injury-and-multiple-organ-failure-in-a-17-day-old-newborn-when-pathology-makes-the-difference
#18
Marie-Michèle Gaudreault-Tremblay, Catherine Litalien, Natalie Patey, Aicha Merouani
Rationale: Acute tubulointerstitial nephritis (ATIN) in children is most commonly due to allergic drug reactions. In neonates, diagnosis of ATIN is clinically suspected and a kidney biopsy is not routinely performed. Presenting concern: A 17-day-old newborn presented with vomiting and dehydration, along with anuric acute kidney injury, severe electrolyte disturbances, hypocomplementemia, and thrombocytopenia. Abdominal ultrasound revealed bilateral nephromegaly and hepatosplenomegaly...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/30304213/chemical-composition-and-evaluation-of-antileishmanial-and-cytotoxic-activities-of-the-essential-oil-from-leaves-of-cryptocarya-aschersoniana-mez-lauraceae-juss
#19
Priscila M DE Andrade, Daiana C DE Melo, Ana Elisa T Alcoba, Walnir G Ferreira Júnior, Mariana C Pagotti, Lizandra G Magalhães, Tainá C L Dos Santos, Antônio E M Crotti, Cassia C F Alves, Mayker L D Miranda
Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID...
July 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/30304137/tuberculous-peritonitis-following-intestinal-perforation-in-malignancy
#20
Jiyoung Hwang, Seong Sook Hong, Hyun-Joo Kim, Yun-Woo Chang, Bo Da Nam, Eunsun Oh, EunJi Lee
Tuberculous peritonitis is one of the most common causes of exudative ascites, especially in the young, and is an important cause of extra-pulmonary disease. However, tuberculous peritonitis is challenging to diagnose because there are no pathognomonic clinical features or imaging findings. Therefore, it is commonly misdiagnosed as another type of peritoneal disease, especially so in elderly patients with malignant disease. In this report, we described two cases of tuberculous peritonitis that were observed after intestinal perforation in elderly patients with malignancies...
May 2018: Revista da Associação Médica Brasileira
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