Cécile Poulain, Yoann Launey, Marwan Bouras, Karim Lakhal, Laura Dargelos, Lise Crémet, Sophie-Anne Gibaud, Stephane Corvec, Philippe Seguin, Bertrand Rozec, Karim Asehnoune, Fanny Feuillet, Antoine Roquilly
BACKGROUND: We aimed to determine whether implementing antimicrobial stewardship based on multiplex bacterial PCR examination of respiratory fluid can enhance outcomes of critically ill patients with hospital-acquired pneumonia (HAP). METHODS: We conducted a quality improvement study in two hospitals in France. Adult patients requiring invasive mechanical ventilation with a diagnosis of HAP were included. In the pre-intervention period (August 2019 to April 2020), antimicrobial therapy followed European guidelines...
February 12, 2024: Anaesthesia, Critical Care & Pain Medicine