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I A Oyemitan, C A Elusiyan, E O Akinkunmi, E M Obuotor, M A Akanmu, T A Olugbade
ETHNOPHARMACOLOGICAL RELEVANCE: Dennettia tripetala Baker f. belonging to the family Annonaceae is an important food and medicinal plant used in some local communities in Southwest Nigeria. AIMS OF THE STUDY: The study aims at determining the chemical composition of the essential oil of different morphological parts of D. tripetala, the memory enhancing and anticholinesterase activities as well as the antimicrobial properties. MATERIALS AND METHODS: Essential oil of the morphological parts namely the fresh fruits, dried fruits, dried seeds and fresh leaves were obtained by hydrodistillation and analysed by GC-FID and GC-MS...
October 17, 2018: Journal of Ethnopharmacology
Abolanle Saheed Adekunle, John Adekunle Oyedele Oyekunle, Ibitomilola Janet Ola, Olaoluwa Ruth Obisesan, Nobanathi Wendy Maxakato
The study was carried out to determine the presence and concentration of polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs) in some personal care products in Nigeria. Commonly used consumer care products grouped into four classes, namely: plastics, cosmetics, disinfectants and washing products, were purchased from some supermarkets in Ile-Ife, Nigeria. The solid samples were pulverized and the PAHs and OCPs were extracted with n-hexane and dichloromethane, respectively using Soxhlet extraction method, while the liquid samples were extracted using liquid-liquid extraction method...
2018: Toxicology Reports
Sahar Nassirpour, Paul Chang, Thomas Kirchner, Anke Henning
The aim of this work was to use post-processing methods to improve the data quality of metabolite maps acquired on the human brain at 9.4 T with accelerated acquisition schemes. This was accomplished by combining an improved sensitivity encoding (SENSE) reconstruction with a B0 correction of spatially over-discretized magnetic resonance spectroscopic imaging (MRSI) data. Since MRSI scans suffer from long scan duration, investigating different acceleration techniques has recently been the focus of several studies...
October 18, 2018: NMR in Biomedicine
Okan Özkaya, Kemal Şen, Christophe Aubert, Ömür Dündar, Ziya Gunata
Free and glycosidically bound volatiles from two major tomato cultivars ( Lycopersicon esculantum L . cv . Alida and Merve) of Turkey were determined. Free volatile compounds were extracted using liquid-liquid microextraction, while bound volatiles were extracted using solid phase extraction. The compounds were analyzed using GC-FID and GC-MS. Alida showed presence of, 39 free and 32 bound aroma compounds again 38 free and 31 bound aroma compounds is Merve. The odor activity values of the volatile compounds suggested that hexanal, (Z)-3-hexenal, (E,Z)-2,4-decadienal, (E,E)-2,4-decadienal and 2-phenylethanol were most significant odorants in both cultivars...
November 2018: Journal of Food Science and Technology
Federica Pellati, Virginia Brighenti, Johanna Sperlea, Lucia Marchetti, Davide Bertelli, Stefania Benvenuti
Cannabis sativa L. is a dioecious plant belonging to the Cannabaceae family. The main phytochemicals that are found in this plant are represented by cannabinoids, flavones, and terpenes. Some biological activities of cannabinoids are known to be enhanced by the presence of terpenes and flavonoids in the extracts, due to a synergistic action. In the light of all the above, the present study was aimed at the multi-component analysis of the bioactive compounds present in fibre-type C. sativa (hemp) inflorescences of different varieties by means of innovative HPLC and GC methods...
October 14, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
B Zhang, S S Li, L Li, H Y Wei, M P Zhang, W Zou, Z H Zhang
Objective: To establish a method for the determination of diethyl phthalate by gas chromatography in the air of workplaces. Methods: Diethyl phthalate in the air of workplace was collected throμgh glass fiber filter, eluted with methylbenzene, and detected by gas chromatography coupled with FID detectors. Results: The linear range of diethyl phthalate determined by this method was 14.0~1 400 μg/ml, y=2.09801x-3.66229, and the coefficient correlation was 0.999 99. The detection limit was 1.10 μg/ml, and the minimum detection concentration was 0...
August 20, 2018: Chinese Journal of Industrial Hygiene and Occupational Diseases
Jinglan Feng, Fei Zhang, Jiahui Zhao, Wei Guo, Jianhui Sun
PDMS 200 fluid (the mixture) was used as standard for quantification of linear dimethylsiloxanes (L5-L16) in environmental matrices. However, the quantification of individual dimethylsiloxane in PDMS 200 fluid by GC-FID was not established or detailed described in many real studies. To solve this problem, we did this research and the principal results were as follows: fifteen compounds in PDMS 200 fluid, including D7, L5 to L16 (12 linear dimethylsiloxanes) and 2 unknown compounds, were identified using GC-MS...
October 3, 2018: Journal of Chromatography. A
Anna Carolina F Valadares, Cassia Cristina F Alves, José Milton Alves, Isabella P B DE Deus, Josemar G DE Oliveira Filho, Tainá Caroline L Dos Santos, Herbert Júnior Dias, Antônio Eduardo M Crotti, Mayker L D Miranda
Even though essential oils from Piper aduncum (Piperaceae) have different biological activities, little is known about their application to agricultural areas. White mold is a plant disease caused by the phytopathogen Sclerotinia sclerotiorum, which needs to be controlled by alternative measures. This study aimed at evaluating the effect of essential oils from P. aduncum leaves (PL-EO) and inflorescences (PI-EO) on the mycelial growth of S. sclerotiorum. Essential oils from P. aduncum were obtained by hydrodistillation by a Clevenger-type apparatus while their chemical composition was analyzed by GC-MS and GC-FID...
September 2018: Anais da Academia Brasileira de Ciências
Priscila M DE Andrade, Daiana C DE Melo, Ana Elisa T Alcoba, Walnir G Ferreira Júnior, Mariana C Pagotti, Lizandra G Magalhães, Tainá C L Dos Santos, Antônio E M Crotti, Cassia C F Alves, Mayker L D Miranda
Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID...
July 2018: Anais da Academia Brasileira de Ciências
Dominika Krenczkowska, Krystyna Mojsiewicz-Pieńkowska, Bartosz Wielgomas, Krzysztof Cal, Rafał Bartoszewski, Sylwia Bartoszewska, Zbigniew Jankowski
Dynamic production of cyclic siloxanes: octamethylcyclotetrasiloxane D4, decamethylcyclopentasiloxane D5 and dodecamethylcyclohexasiloxane D6 increases their concentrations in environment. It is considered that both environmental pollution and the usage of personal care products and cosmetics containing cyclic siloxanes can be the main source of the human exposure by transdermal route. The aim of the study was to verify the possibility to overcome the skin barrier by cyclic siloxanes (ATR-FTIR and GC-FID), evaluation of diffusion pathway to stratum corneum SC (Fluorescence microscopy), and determination of depth of permeation to deeper skin layers: epidermis and dermis (ATR-FTIR) and also of potential interaction with SC lipids and proteins (Fluorescence microscopy, ATR-FTIR) and the cytotoxicity studies against HaCaT cells (MTT test)...
September 27, 2018: Chemosphere
Thamires de Oliveira Moura, Franciele Oliveira Santana, Vânia Palmeira Campos, Iara Brandão de Oliveira, Yvonilde Dantas Pinto Medeiros
This work evaluated the presence of contaminants in stored rainwater in 36 polyethylene tanks installed in two rural communities of the semiarid of Bahia, Brazil. Carbonyl compounds were analyzed by High Performance Liquid Chromatography (HPLC-UV), BTEX (Benzene, Toluene, Ethylbenzene and Xylenes) by gas chromatoghaphy (GC-FID), and trace elements by inductively coupled plasma optical emission spectrometry (ICP-OES). Seven carbonyl compounds were quantified including acrolein (<3-115 µg L-1 ), which is considered a potent mutagenic agent, above the potability limit in 75% of the cases...
February 1, 2019: Food Chemistry
Chaoyang Xiong, Zengqi Wen, Juan Yu, Jun Chen, Chao-Pei Liu, Xiaodong Zhang, Ping Chen, Rui-Ming Xu, Guohong Li
BACKGROUND: H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. However, it still remains largely uncharacterized how HIRA complex specifically recognizes and deposits H3.3 to the chromatin, such as promoters and enhancers. RESULTS: In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recognition and direct binding of H3...
October 3, 2018: BMC Biology
Fabiana Busti, Giacomo Marchi, Sara Ugolini, Annalisa Castagna, Domenico Girelli
Anemia in cancer patients is quite common, with remarkable negative impacts on quality of life and overall prognosis. The pathogenesis is complex and typically multifactorial, with iron deficiency (ID) often being a major and potentially treatable contributor. In turn, ID in cancer patients can be due to multiple concurring mechanisms, including bleeding (e.g., in gastrointestinal cancers or after surgery), malnutrition, medications, and hepcidin-driven iron sequestration into macrophages with subsequent iron-restricted erythropoiesis...
September 30, 2018: Pharmaceuticals
Ali Zahraei, Peter W F Arisz, Alexander P van Bavel, Ron M A Heeren
A light oil was separated into four chromatographic fractions that serve as proxy for SARA fractions. The fractions were (semi)quantified on a rod by TLC-flame ionization detection and characterized on a plate with laser desorption ionization-mass spectrometry imaging (TLC-LDI-MS). Comparisons of (semi)quantitative TLC-FID and qualitative TLC-LDI-MS results showed that LDI-MS was most sensitive for detection of molecules in the polar P1 fraction, and, to some extent, for the aromatics fraction, while no signal was observed for the most polar P2 and saturates fractions...
July 19, 2018: Energy & Fuels: An American Chemical Society Journal
Kelly Zhang, Kenji L Kurita, Cadapakam Venkatramani, David Russell
It is highly desirable to have a universal detector that can detect all types of compounds and give a uniform response regardless of the physiochemical properties of the compounds. With such a universal detector, all components in a sample can be accurately quantified without the need for individual standards. This is especially needed for the characterization of unknowns and for non-targeted analysis, or for samples that have no isolated standards available for each component. Over the years, much effort has been put into seeking a universal detection technology...
September 19, 2018: Journal of Pharmaceutical and Biomedical Analysis
Juthaporn Ponphaiboon, Sontaya Limmatvapirat, Amornrut Chaidedgumjorn, Chutima Limmatvapirat
Modified coconut oil (MCO) obtained from the glycerolysis of virgin coconut oil (VCO) and glycerol under various conditions should have different amounts of bioactive fatty acids (FAs) and acylglycerols (AGs). Methods were developed to analyze lauric acid (LA), monolaurin (ML), dilaurin (DL), and trilaurin (TL) in MCO samples using gas chromatography - flame ionization detector (GC-FID) and high performance liquid chromatography - evaporative light scattering detector (HPLC-ELSD). The purpose of this research is to optimize and compare GC-FID and HPLC-ELSD methods for determination of LA, ML, DL, and TL in MCO samples...
November 1, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Marie-Anne Boucher, Héloïse Côté, André Pichette, Lionel Ripoll, Jean Legault
The chemical composition of Tussilago farfara L. essential oil from the Saguenay-Lac-St-Jean region of Quebec, Canada was analyzed by gas chromatography-flame ionisation detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS), and the antibacterial activity of the oil was tested against Escherichia coli and Staphylococcus aureus. Forty-five (45) compounds were identified from the GC profile. The main components were 1-nonene (40.1%), α-phellandrene (26.0%) and ρ-cymene (6.6%). The essential oil demonstrated antibacterial activity against E...
September 27, 2018: Natural Product Research
Zorica S Mitić, Jelena Nikolić, Bojan Zlatković, Sretco Milanovici, Snežana Jovanović, Biljana Nikolić, Gordana Stojanović, Petar Marin
Phytochemical diversity and differentiation of nine native populations of Pinus mugo sensu stricto from Julian Alps, Southern Carpathians and Balkan Peninsula were analyzed in regard to epicuticular wax compounds. GC-MS and GC-FID analyses of n-hexane extracts of needle samples, collected from 118 individuals of P. mugo, revealed presence of six diterpenes, three primary alcohols and 10 n-alkanes ranging from C19 to C29 (except n-alkane C21). According to simple linear regression, contents of epicuticular wax compounds showed generally weak correlations with tested bioclimatic, orographic and geographic parameters, leading to assumption about their genetic conditioning...
September 26, 2018: Chemistry & Biodiversity
Mateusz Urbańczyk, Alexandra Shchukina, Dariusz Gołowicz, Krzysztof Kazimierczuk
NMR spectroscopy, used routinely for structure elucidation, has also become a widely applied tool for process and reaction monitoring. However, the most informative of NMR methods - correlation experiments - are often useless in this kind of applications. The traditional sampling of a multidimensional FID is usually time-consuming, and thus the reaction-monitoring toolbox was practically limited to 1D experiments (with rare exceptions, e.g. single-scan or fast-sampling experiments). Recently, the technique of time-resolved non-uniform sampling (TR-NUS) has been proposed, which allows to use standard multidimensional pulse sequences preserving the temporal resolution close to that achievable in 1D experiments...
September 25, 2018: Magnetic Resonance in Chemistry: MRC
Vanessa S Bomfim, Alceu A Jordão, Larissa G Alves, Francisco E Martinez, José Simon Camelo
BACKGROUND: Human milk, with essential nutrients and long chain polyunsaturated fatty acids (LC-PUFAs) such as the omega 3 and 6 fatty acids is important for development of the central nervous system and the retina in very low birth weight infants (<1,500 g). However, breast milk may not be sufficient to meet these needs. The possibility of supplementing breast milk with a lyophilisate of human milk was explored in this study. The objectives of this study were to determine the total lipid content and the lipid profile of the Human Milk on Baseline (HMB) and that of the Concentrates with the Human Milk + lyophilisate (with lyophilisate of milk in the immediate period (HMCI), at 3 months (HMC3m), and at 6 months (HMC6m) of storage)...
2018: PloS One
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