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Zulfia McCroskey, Nour Sneige, Carolyn R Herman, Ross A Miller, Luz A Venta, Jae Y Ro, Mary R Schwartz, Alberto G Ayala
The aim of this study was to analyze the clinicopathological features of patients with flat epithelial atypia, diagnosed in directional vacuum-assisted biopsy targeting microcalcifications, to identify upgrade rate to in situ ductal or invasive breast carcinoma, and determine factors predicting carcinoma in the subsequent excision. We retrospectively evaluated the histological, clinical, and mammographic features of 69 cases from 65 women, with directional vacuum-assisted biopsy-diagnosed flat epithelial atypia with or without atypical ductal hyperplasia or atypical lobular hyperplasia, which underwent subsequent surgical excision...
February 21, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
Isabelle Théberge, Marie-Hélène Guertin, Nathalie Vandal, Jean-Marc Daigle, Michel-Pierre Dufresne, Nancy Wadden, Rene Shumak, Caroline Samson, André Langlois, Isabelle Larocque, Linda Perron, Éric Pelletier, Jacques Brisson
PURPOSE: The study sought to examine the association between clinical image quality of mammograms and screening sensitivity. METHODS: Four radiologists evaluated the clinical image quality of 374 invasive screen-detected cancers and 356 invasive interval breast cancers for which quality evaluation of screening mammograms could be assessed from cancers diagnosed among participants in the Quebec Breast Cancer Screening Program in 2007. Quality evaluation was based on the Canadian Association of Radiologists accreditation criteria, which are similar to those of the American College of Radiology...
February 2018: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
Cecilia J Strudley, Kenneth C Young, Lucy M Warren
OBJECTIVE: To compare breast cancer detection using a single 8MP display with using a standard pair of 5MP monitors. METHODS: An observer study was carried out in which mammograms were read using full field views only, and again with the additional use of magnified quadrant views. Seven observers read 300 cases, one view per breast, using each display type. Cases comprised 100 normal cases and 200 cases with cancers of subtle or very subtle appearance: 100 with malignant calcification clusters and 100 with non-calcified lesions...
February 13, 2018: British Journal of Radiology
Diana S M Buist, Linn Abraham, Christoph I Lee, Janie M Lee, Constance Lehman, Ellen S O'Meara, Natasha K Stout, Louise M Henderson, Deirdre Hill, Karen J Wernli, Jennifer S Haas, Anna N A Tosteson, Karla Kerlikowske, Tracy Onega
Importance: There is little evidence on population-based harms and benefits of screening breast magnetic resonance imaging (MRI) in women with and without a personal history of breast cancer (PHBC). Objective: To evaluate biopsy rates and yield in the 90 days following screening (mammography vs magnetic resonance imaging with or without mammography) among women with and without a PHBC. Design, Setting, and Participants: Observational cohort study of 6 Breast Cancer Surveillance Consortium (BCSC) registries...
February 12, 2018: JAMA Internal Medicine
Marilyn M Schapira, William E Barlow, Emily F Conant, Brian L Sprague, Anna N A Tosteson, Jennifer S Haas, Tracy Onega, Elisabeth F Beaber, Martha Goodrich, Anne Marie McCarthy, Sally D Herschorn, Celette Sugg Skinner, Tory O Harrington, Berta Geller
RATIONALE AND OBJECTIVES: The objective of this study was to evaluate the association of communication practices with timely follow-up of screening mammograms read as Breast Imaging Reporting and Data Systems (BI-RADS) 0 in the Population-based Research Optimizing Screening through Personalized Regimens (PROSPR) consortium. MATERIALS AND METHODS: A radiology facility survey was conducted in 2015 with responses linked to screening mammograms obtained in 2011-2014...
February 9, 2018: Academic Radiology
Alana A Lewin, Yiming Gao, Leng Leng Lin Young, Marissa L Albert, James S Babb, Hildegard K Toth, Linda Moy, Samantha L Heller
PURPOSE: To evaluate whether false-positive stereotactic vacuum-assisted breast biopsy (SVAB) affects subsequent mammographic screening adherence. MATERIALS AND METHODS: This Institutional Review Board-approved, HIPAA-compliant retrospective review of women with SVAB was performed between 2012 and 2014. Patient age, clinical history, biopsy pathology, and first postbiopsy screening mammogram were reviewed. Statistical analyses were performed using Fisher's exact, Mann-Whitney, and χ2 tests...
February 8, 2018: Journal of the American College of Radiology: JACR
Stephanie A Cohen, Courtney Lynam Scherr, Dawn M Nixon
Women with BRCA mutations, at significantly increased risk for breast and ovarian cancer, do not consistently adhere to management guidelines due to lack of awareness and challenges tracking appointments. We developed an iPhone application (app) to help BRCA carriers manage their surveillance. We explored baseline awareness and adherence to surveillance guidelines and analytic data from 21 months of app use. Descriptive statistics were calculated on responses (N = 86) to a survey about surveillance awareness and practices...
February 10, 2018: Journal of Genetic Counseling
João Otávio Bandeira Diniz, Pedro Henrique Bandeira Diniz, Thales Levi Azevedo Valente, Aristófanes Corrêa Silva, Anselmo Cardoso de Paiva, Marcelo Gattass
BACKGROUND AND OBJECTIVE: The processing of medical image is an important tool to assist in minimizing the degree of uncertainty of the specialist, while providing specialists with an additional source of detect and diagnosis information. Breast cancer is the most common type of cancer that affects the female population around the world. It is also the most deadly type of cancer among women. It is the second most common type of cancer among all others. The most common examination to diagnose breast cancer early is mammography...
March 2018: Computer Methods and Programs in Biomedicine
Mark C Murphy, Louise Coffey, Ailbhe C O'Neill, Cecily Quinn, Ruth Prichard, Sorcha McNally
AIMS AND OBJECTIVES: The aim of this study was to determine if the synthetic C view acquired at digital breast tomosynthesis (DBT) would give adequate information to confirm a malignancy and could obviate the need to review all the tomosynthesis image data set. METHODS: All patients with biopsy-proven breast cancer recalled from screening mammograms between May and September 2016 were included for review. For each patient, the screening 2D mammogram, the synthetic C view, and the DBT images were reviewed by three breast radiologists and each assigned a BIRADS code...
February 9, 2018: Irish Journal of Medical Science
Eun-Kyung Kim, Hyo-Eun Kim, Kyunghwa Han, Bong Joo Kang, Yu-Mee Sohn, Ok Hee Woo, Chan Wha Lee
We assessed the feasibility of a data-driven imaging biomarker based on weakly supervised learning (DIB; an imaging biomarker derived from large-scale medical image data with deep learning technology) in mammography (DIB-MG). A total of 29,107 digital mammograms from five institutions (4,339 cancer cases and 24,768 normal cases) were included. After matching patients' age, breast density, and equipment, 1,238 and 1,238 cases were chosen as validation and test sets, respectively, and the remainder were used for training...
February 9, 2018: Scientific Reports
K Baxstrom, B A Peterson, C Lee, R I Vogel, A H Blaes
BACKGROUND: Women treated with chest radiation for Hodgkin lymphoma (HL) are at significantly increased risk of breast cancer and cardiovascular disease. HL survivors are recommended to have annual dual screening with mammogram (MMG) and breast magnetic resonance imaging (MRI). They are also recommended to undergo echocardiogram (echo) 5 years after completion of radiation. We performed a pilot study to characterize the women who are and are not receiving proper dual screening for breast cancer and baseline echo, and to examine the impact of a LTFU clinic consultation on screening...
February 7, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
M J Michell, B Batohi
Digital breast tomosynthesis (DBT) is a modified mammographic technique that overcomes some of the limitations of full-field digital mammography (2DDM) by eliminating the effect of overlapping breast tissue. In the UK, DBT is utilised in both the symptomatic setting and in breast screening assessment clinics. A literature search was conducted from 2010-2017 to ensure that the most recent developments in DBT technology, clinical applications, and assessment of its usefulness in breast screening were reviewed...
February 5, 2018: Clinical Radiology
Gianfranco Paternò, Paolo Cardarelli, Adriano Contillo, Mauro Gambaccini, Angelo Taibi
Advanced applications of digital mammography such as dual-energy and tomosynthesis require multiple exposures and thus deliver higher dose compared to standard mammograms. A straightforward manner to reduce patient dose without affecting image quality would be removal of the anti-scatter grid, provided that the involved reconstruction algorithms are able to take the scatter figure into account [1]. Monte Carlo simulations are very well suited for the calculation of X-ray scatter distribution and can be used to integrate such information within the reconstruction software...
January 2018: Physica Medica: PM
Sau Yeen Loke, Ann Siew Gek Lee
Breast cancer (BC) is the most frequently diagnosed cancer and the most common cause of cancer-related mortality among women worldwide. Despite the extensive use of mammography as the gold standard for BC screening, the occurrences of false-positive and false-negative mammograms, as well as overdiagnosis, remain a concern in breast oncology. Thus, there is a need to identify reliable biomarkers from an easily accessible source that could generate cost-effective assays feasible for routine screening. Blood-based biomarkers may offer an alternative non-invasive strategy to improve cancer screening...
February 5, 2018: European Journal of Cancer
Qingxia Kong, Susana Mondschein, Ana Pereira
Chile has lower breast cancer incidence rates compared to those in developed countries. Our public health system aims to perform 10 biennial screening mammograms in the age group of 50 to 69 years by 2020. Using a dynamic programming model, we have found the optimal ages to perform 10 screening mammograms that lead to the lowest lifetime death rate and we have evaluated a set of fixed inter-screening interval policies. The optimal ages for the 10 mammograms are 43, 47, 51, 54, 57, 61, 65, 68, 72, and 76 years, and the most effective fixed inter-screening is every four years after the 40 years...
February 5, 2018: Revista de Saúde Pública
Sunita Pal, Debra M Ikeda, Robert A Jesinger, L Jake Mickelsen, Christina A Chen, David B Larson
OBJECTIVE: The purpose of this project was to achieve sustained improvement in mammographic breast positioning in our department. MATERIALS AND METHODS: Between June 2013 and December 2016, we conducted a team-based performance improvement initiative with the goal of improving mammographic positioning. The team of technologists and radiologists established quantitative measures of positioning performance based on American College of Radiology (ACR) criteria, audited at least 35 mammograms per week for positioning quality, displayed performance in dashboards, provided technologists with positioning training, developed a supportive environment fostering technologist and radiologist communication surrounding mammographic positioning, and employed a mammography positioning coach to develop, improve, and maintain technologist positioning performance...
February 7, 2018: AJR. American Journal of Roentgenology
Eralda Mema, Emma Cho, Yun-Kyoung Ryu, Priya Jadeja, Ralph Wynn, Brett Taback, Richard Ha
PURPOSE: To evaluate whether in the setting of negative diagnostic mammogram for breast pain additional ultrasound is necessary. METHODS: Retrospective IRB-approved review of our database identified 8085 women who underwent ultrasound evaluation for breast pain from 1/1/2013-12/31/2013. Of 8085 women, 559 women had mammogram evaluation preceding the ultrasound and these women comprise the basis of this study. The patient's age, type of mammogram examination (screening or diagnostic), Breast Imaging-Reporting and Data System (BI-RADS) breast density (BD), type of breast pain (focal, diffuse, cyclical, unilateral, bilateral), additional breast symptoms (palpable concern, nipple discharge, skin changes, others), mammogram or ultrasound findings and final BI-RADS assessment, follow-up imaging, and follow-up biopsy results were reviewed and recorded...
January 9, 2018: Current Problems in Diagnostic Radiology
William P Adams, Richard Baxter, Caroline Glicksman, Bruce A Mast, Michael Tantillo, Bruce W Van Natta
Background: Mastopexy and reduction mammoplasty are often limited by the patient's poor native soft tissue quality, resulting in ptosis recurrence and loss of rejuvenated surgical results. Surgical scaffolds and acellular dermal matrices are used in these procedures to provide physical and mechanical stabilization of weakened or compromised tissue. GalaFLEX scaffold, made from poly-4-hydroxybutyrate (P4HB), is a next-generation product for soft tissue reinforcement that resorbs gradually while aiding tissue regeneration to achieve excellent outcomes...
February 1, 2018: Aesthetic Surgery Journal
Moayyad E Suleiman, Patrick C Brennan, Ernest Ekpo, Peter Kench, Mark F McEntee
OBJECTIVE: This work proposes the use of mammographic breast density (MBD) to estimate actual glandular dose (AGD), and assesses how AGD compares to mean glandular dose (MGD) estimated using Dance et al. METHOD: HASH(0x4193200) METHODS: A retrospective sample of anonymised mammograms (52,405) was retrieved from a central database. Technical parameters and patient characteristics were exported from the Digital Imaging and Communication in Medicine (DICOM) header using third party software...
February 5, 2018: British Journal of Radiology
Michelle Skop, Justin Lorentz, Mobin Jassi, Danny Vesprini, Gillian Einstein
Men with BRCA1 or BRCA2 gene mutations are at increased risk of developing breast cancer and may have an indication for breast cancer screening using mammography. Since breast cancer is often viewed as a woman's disease, visibilizing and understanding men's experience of having a BRCA mutation and specifically, of screening for breast cancer through mammography, were the objectives of this research study. The theoretical framework of interpretive phenomenology guided the process of data collection, coding, and analysis...
February 1, 2018: American Journal of Men's Health
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