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Patrick Mun Yew Chan, Niketa Chotai, Eileen Shujuan Lai, Pei Yi Sin, Juliana Chen, Sarah Qinghui Lu, Mui Heng Goh, Bee Kiang Chong, Bernard Chi Shern Ho, Ern Yu Tan
BACKGROUND: Borderline risk lesions such as flat epithelial atypia (FEA) are increasingly being diagnosed on biopsy. The need for surgery is being debated. In this study, we determined the frequency of histological upgrade following a diagnosis of FEA on biopsy and evaluated potential predictive factors. METHODS: Retrospective review was done of 194 women who underwent biopsy of indeterminate lesions (total 195 lesions) that were diagnosed as FEA. The review covered a 10-year period...
October 14, 2017: Breast: Official Journal of the European Society of Mastology
Lorna Bittencourt, Isabel C Scarinci
Although it has been show that early detection through mammograms is the most effective way to reduce breast cancer mortality, breast cancer is the leading cause of cancer deaths among women worldwide with survival rates being even lower in low- and middle-income countries as compared to high-income countries. Despite the availability of breast cancer screening programs in Brazil through the public health system, some women do not participate in these programs due to structural and/or inter/intrapersonal barriers...
September 26, 2017: Health Promotion International
Ravi K Samala, Heang-Ping Chan, Lubomir M Hadjiiski, Mark A Helvie, Kenny Cha, Caleb Richter
Transfer learning in deep convolutional neural networks (DCNNs) is an important step in its application to medical imaging tasks. We propose a multi-task transfer learning DCNN with the aims of translating the 'knowledge' learned from non-medical images to medical diagnostic tasks through supervised training and increasing the generalization capabilities of DCNNs by simultaneously learning auxiliary tasks. We studied this approach in an important application: classification of malignant and benign breast masses...
October 16, 2017: Physics in Medicine and Biology
Aya A Mitani, Phoebe E Freer, Kerrie P Nelson
PURPOSE: Interpretation of screening tests such as mammograms usually require a radiologist's subjective visual assessment of images, often resulting in substantial discrepancies between radiologists' classifications of subjects' test results. In clinical screening studies to assess the strength of agreement between experts, multiple raters are often recruited to assess subjects' test results using an ordinal classification scale. However, using traditional measures of agreement in some studies is challenging because of the presence of many raters, the use of an ordinal classification scale, and unbalanced data...
September 22, 2017: Annals of Epidemiology
Jane Peart, Glen Thomson, Stephen Wood
The developing asymmetry has a 12-15% risk of malignancy but poses challenges of detection and interpretation due to the lack of typical features of cancer and the frequent absence of an ultrasound correlate. Failure to biopsy these lesions may lead to delayed diagnosis of breast cancer.
October 11, 2017: Journal of Medical Imaging and Radiation Oncology
Thijs Kooi, Nico Karssemeijer
We investigate the addition of symmetry and temporal context information to a deep convolutional neural network (CNN) with the purpose of detecting malignant soft tissue lesions in mammography. We employ a simple linear mapping that takes the location of a mass candidate and maps it to either the contralateral or prior mammogram, and regions of interest (ROIs) are extracted around each location. Two different architectures are subsequently explored: (1) a fusion model employing two datastreams where both ROIs are fed to the network during training and testing and (2) a stagewise approach where a single ROI CNN is trained on the primary image and subsequently used as a feature extractor for both primary and contralateral or prior ROIs...
October 2017: Journal of Medical Imaging
Seetha Lakshmi, Susan E Beekmann, Philip M Polgreen, Allan Rodriguez, Maria L Alcaide
Models of care for people living with HIV (PLWH) have varied over time due to long term survival, development of HIV-associated non-AIDS conditions, and HIV specific primary care guidelines that differ from those of the general population. The objectives of this study are to assess how often infectious disease (ID) physicians provide primary care for PLWH, assess their practice patterns and barriers in the provision of primary care. We used a 6-item survey electronically distributed to ID physician members of Emerging Infections Network (EIN)...
October 9, 2017: AIDS Care
Camila Soares Lima Corrêa, Luanna Couto Pereira, Isabel Cristina Gonçalves Leite, Vívian Assis Fayer, Maximiliano Ribeiro Guerra, Maria Teresa Bustamante-Teixeira
OBJECTIVE: to assess the results of indicators related to the supply of mammography and level of adequacy of diagnostic confirmation for mammograms with suspicious findings of malignancy in Minas Gerais state and its health macroregions. METHODS: this is an evaluation study performed with data from the Breast Cancer Information System and the Outpatient Information System for the years 2010 and 2011. RESULTS: : the ratio of mammograms in women aged 50 to 69 years was of 0...
July 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
Silvina C Mema, Huiming Yang, Sherry Elnitsky, Zhichang Jiang, Marcus Vaska, Linan Xu
BACKGROUND: Women in rural and remote northern Alberta access breast cancer screening through a mobile mammogram program (Screen Test). The Enhanced Access to Cervical and Colorectal Cancer Screening (EACS) project was a 2-year pilot that aimed to integrate cervical and colorectal cancer screening with the Screen Test program. This study compares cervical and colorectal cancer screening uptake among women screened through the pilot (Screen Test-EACS) versus Screen Test. METHODS: Screen Test-EACS was offered between 2013 and 2015 in selected rural and remote sites, with a focus on hard-to-reach women living in First Nations, Métis and Hutterite communities...
October 3, 2017: CMAJ Open
Belinda Vicuña, Harold D Delaney, Kristina G Flores, Lori Ballinger, Melanie Royce, Zoneddy Dayao, Tuya Pal, Anita Y Kinney
Until recently, genetic testing for hereditary breast cancer has primarily focused on pathogenic variants in the BRCA1 and BRCA2 (BRCA) genes. However, advances in DNA sequencing technologies have made simultaneous testing for multiple genes possible. We examined correlates of interest in multigene panel testing and risk communication preferences in an ethnically diverse sample of women who tested negative for BRCA mutations previously but remain at high risk based on their family history (referred to as "BRCA-uninformative") and their at-risk female family members...
October 2, 2017: Journal of Community Genetics
Matthew B Morgan, Elizabeth Young, Scott Harada, Nicole Winkler, Joanna Riegert, Tony Jones, Nan Hu, Matthew Stein
In screening mammography, accessing prior examination images is crucial for accurate diagnosis and avoiding false-positives. When women visit multiple institutions for their screens, these "outside" examinations must be retrieved for comparison. Traditionally, prior images are obtained by faxing requests to other institutions and waiting for standard mail (film or CD-ROM), which can greatly delay report turnaround times. Recently, advancements in cloud-based image transfer technology have opened up more efficient options for examination transfer between institutions...
September 29, 2017: Journal of the American College of Radiology: JACR
Joish Upendra Kumar, Vivek Sreekanth, Harikiran R Reddy, Aishwarya B Sridhar, Niveditha Kodali, Anitha S Prabhu
INTRODUCTION: Breast cancer incidence and related mortality is increasing in Indian women. Indian ladies hesitate to seek medical care for breast related issues. Screening mammography, proved to effectively reduce mortality, has been deemed not feasible in Indian context due to cost considerations. The suggested alternatives have not been proven to improve mortality rates. AIM: To find the relevance of screening mammography camp among Indian women. MATERIALS AND METHODS: A week long screening mammography camp was organized in a tertiary care hospital...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
R Pape, K Spuur, P Umo
INTRODUCTION: The aim of this research is to evidence for the first time the breast density of Papua New Guinean (PNG) women as described by mammographic parenchymal patterns (MPPs) and profile breast cancer risk; to examine the relationship of age and MPPs. METHODS: A retrospective analysis of 1161 screening mammograms of women who had undergone imaging at the Pacific International Hospital (PIH) was undertaken. Mammograms were classified into one of five Tabár MPPs; age was recorded in years...
November 2017: Radiography
K Taylor, D Parashar, G Bouverat, A Poulos, R Gullien, E Stewart, R Aarre, P Crystal, M Wallis
INTRODUCTION: Optimum mammography positioning technique is necessary to maximise cancer detection. Current criteria for mammography appraisal lack reliability and validity with a need to develop a more objective system. We aimed to establish current international practice in assessing image quality (IQ), of screening mammograms then develop and validate a reproducible assessment tool. METHODS: A questionnaire sent to centres in countries undertaking population screening identified practice, participants for an expert panel (EP) of radiologists/radiographers and a testing panel (TP) of radiographers...
November 2017: Radiography
Garth H Rauscher, Firas Dabbous, Therese A Dolecek, Sarah M Friedewald, Katherine Tossas-Milligan, Teresita Macarol, W Thomas Summerfelt
PURPOSE: Compared to non-Latina (nL) white women, nL black women are diagnosed with more aggressive breast cancers, which in turn should be more likely to go undetected on screening mammography and subsequently arise as interval breast cancer (IBC). We sought to estimate the extent of an anticipated racial disparity in IBC within a single, large health care organization. METHODS: The present analysis focuses on 4357 breast cancers diagnosed between 2001 and 2012 and within 18 months of a screening mammogram (N = 714,218)...
September 20, 2017: Annals of Epidemiology
Ying Liu, Rulla M Tamimi, Graham A Colditz, Kimberly A Bertrand
PURPOSE: Consumption of alcoholic beverages during adolescence and early adulthood has been consistently associated with higher breast cancer risk. The influence of alcohol consumption early in life on mammographic breast density, a marker of breast cancer risk, is inconclusive. This study examined associations of alcohol consumption across the life course with premenopausal mammographic density. METHODS: The study population included 1211 premenopausal women in the Nurses' Health Study II without cancer, who recalled their alcohol consumption at age 15 through enrollment in 1989 (baseline), and had mammograms available...
September 26, 2017: Breast Cancer Research and Treatment
Kayla R Mendel, Hui Li, Li Lan, Cathleen M Cahill, Victoria Rael, Hiroyuki Abe, Maryellen L Giger
The robustness of radiomic texture analysis across different manufacturers of mammography imaging systems is investigated. We quantified feature robustness across mammography manufacturers using a dataset of 111 women who underwent consecutive screening mammography on both general electric and Hologic systems. In each mammogram, a square region of interest (ROI) directly behind the nipple was manually selected. Radiomic features describing parenchymal patterns were automatically extracted on each ROI. Feature comparisons were conducted between manufacturers (and breast densities) using newly developed robustness metrics descriptive of correlation, equivalence, and variability...
January 2018: Journal of Medical Imaging
Melanie Thomas, Monique James, Eric Vittinghoff, Jennifer M Creasman, Dean Schillinger, Christina Mangurian
OBJECTIVE: This study examined mammogram screening rates among women with severe mental illness by using a socioecological framework. Because it has been shown that people with severe mental illness receive less preventive health care overall, the analysis included psychosocial predictors of mammogram screening rates in a cohort of women with severe mental illness. METHODS: This retrospective cohort study (N=14,651) used existing statewide data for women ages 48-67 in California with Medicaid insurance who received treatment in the specialty mental health care system...
September 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
I P L Houben, P Van de Voorde, C R L P N Jeukens, J E Wildberger, L F Kooreman, M L Smidt, M B I Lobbes
OBJECTIVE: Contrast-enhanced spectral mammography (CESM) is a reliable problem solving tool in the work-up of women recalled from breast cancer screening. We evaluated additional findings caused by CESM alone and outweighed them against the disadvantages of this technique. METHODS: From December 2012 to December 2015, all women recalled from screening who underwent CESM were considered for this study. Radiation exposure and number of adverse contrast reactions were analysed...
September 2017: European Journal of Radiology
Katerina Lekanidi, Phil Dilks, Tamara Suaris, Steffan Kennett, Hema Purushothaman
PURPOSE: The aim of this study was to determine the features that make interval cancers apparent on the preceding screening mammogram and determine whether changes in the ways of performing the interval cancer review will affect the true interval cancer rate. MATERIALS AND METHODS: This study was approved by the clinical governance committee. Mammograms of women diagnosed with an interval cancer were included in the study if they had been allocated to either the "suspicious signs" group or "subtle signs" group, during the historic interval cancer review...
September 2017: European Journal of Radiology
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