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https://www.readbyqxmd.com/read/28107436/a-micro-ct-study-in-patients-with-breast-microcalcifications-using-a-mathematical-algorithm-to-assess-3d-structure
#1
David Kenkel, Zsuzsanna Varga, Heike Heuer, Konstantin J Dedes, Nicole Berger, Lukas Filli, Andreas Boss
PURPOSE: The aim of this study was to evaluate the relevance of the three-dimensional (3D) structure of breast microcalcifications (MC) as a predictor of malignancy using highly resolved micro-computed tomography (micro-CT) datasets of biopsy samples. MATERIAL AND METHODS: The study included 28 women with suspicious MC in their mammogram undergoing vacuum-assisted biopsy. Directly after the intervention, the specimens were scanned in a micro-CT with an isometric spatial resolution of 9 μm...
2017: PloS One
https://www.readbyqxmd.com/read/28103550/estimating-the-accuracy-level-among-individual-detections-in-clustered-microcalcifications
#2
Maria Sainz de Cea, Robert Nishikawa, Yongyi Yang
Computerized detection of clustered microcalcifica tions (MCs) in mammograms often suffers from the occurrence of false positives (FPs), which can vary greatly from case to case. We investigate how to apply statistical estimation to determine the number of FPs that are present in a detected MC lesion. First, we describe the number of true positives (TPs) by a Poisson-Binomial probability distribution, wherein a logistic regression model is trained to determine the probability for an individual detected MC to be a TP based on its detector output...
January 17, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28103125/opt-out-patient-navigation-to-improve-breast-and-cervical-cancer-screening-among-homeless-women
#3
Ramin Asgary, Ramesh Naderi, Juan Wisnivesky
BACKGROUND: A patient navigation model was implemented to improve breast and cervical cancer screening among women who were homeless in five shelters and shelter clinics in New York City in 2014. MATERIALS AND METHODS: Navigation consisted of opt-out screening to eligible women; cancer health and screening education; scheduling and following up for screening completion, obtaining, and communicating results to patients and providers; and care coordination with social services organizations...
January 19, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28102696/compression-forces-used-in-the-norwegian-breast-cancer-screening-program
#4
Gunvor G Waade, Nataliia Moshina, Sofie Sæbuødegård, Peter Hogg, Solveig Hofvind
OBJECTIVES: Compression is used in mammography to reduce breast thickness, which is claimed to improve image quality and reduce radiation dose. In the XXX Breast Cancer Screening Program (XBCSP), the recommended range of compression force for full field digital mammography is 11-18 kg (108-177 Newton [N]). This is the first study to investigate the compression force used in the program. METHODS: The study included information from 17,951 randomly selected women screened with FFDM at 14 breast centres in the XBCSP, January-March 2014...
January 19, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28097214/location-and-lesion-dependent-estimation-of-mammographic-background-tissue-complexity
#5
Ali Avanaki, Kathryn Espig, Tom Kimpe
We specify a notion of perceived background tissue complexity (BTC) that varies with lesion shape, lesion size, and lesion location in the image. We propose four unsupervised BTC estimators based on: perceived pre and postlesion similarity of images, lesion border analysis (LBA; conspicuous lesion should be brighter than its surround), tissue anomaly detection, and local energy. The latter two are existing methods adapted for location- and lesion-dependent BTC estimation. For evaluation, we ask human observers to measure BTC (threshold visibility amplitude of a given lesion inserted) at specified locations in a mammogram...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28087969/axillary-accessory-breast-carcinoma-masquerading-as-axillary-abscess-a-case-report
#6
S Y Lim, S L Jee, T Gee, E Nor Aina
Accessory breast is a frequently seen developmental breast abnormality, commoner among Asians than Caucasians. This ectopic breast tissue shares many similarities as the normal breast tissue, and although subjected to the same pathological processes, accessory breast carcinoma is rare. As locations of the accessory breast may be variable, detection of pathological lesions through clinical examinations and standard diagnostic tools (i.e., mammogram) can be difficult. Staging and management should be tailored-made according to the location of the accessory breast as well as its known pattern of lymphatic drainage...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28070772/primary-care-providers-beliefs-and-recommendations-and-use-of-screening-mammography-by-their-patients
#7
Jennifer S Haas, William E Barlow, Marilyn M Schapira, Charles D MacLean, Carrie N Klabunde, Brian L Sprague, Elisabeth F Beaber, Jane S Chen, Asaf Bitton, Tracy Onega, Kimberly Harris, Anna N A Tosteson
BACKGROUND: Revised breast cancer screening guidelines have fueled debate about the effectiveness and frequency of screening mammography, encouraging discussion between women and their providers. OBJECTIVE: To examine whether primary care providers' (PCPs') beliefs about the effectiveness and frequency of screening mammography are associated with utilization by their patients. DESIGN: Cross-sectional survey data from PCPs (2014) from three primary care networks affiliated with the Population-based Research Optimizing Screening through Personalized Regimens (PROSPR) consortium, linked with data about their patients' mammography use (2011-2014)...
January 9, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28069161/the-value-of-routine-screening-mammography-in-women-aged-35-39-years-in-a-symptomatic-breast-unit
#8
A Buckley, N Healy, A Quinn, S A O'Keeffe
AIM: To determine the breast cancer detection rate at routine bilateral screening mammography in women aged 35-39 years attending a symptomatic breast clinic, in women of population-risk profile with a normal clinical examination. METHODS AND MATERIALS: A retrospective analysis of all mammograms performed on patients aged 35-39 years at St James's Hospital from 2011-2015 was carried out. Patients with moderate or high familial risk of breast cancer, personal breast cancer history or chest radiation, males, general practitioner (GP) and internal hospital referrals, and those with abnormal clinical examinations were excluded...
January 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28068940/early-life-socioeconomic-environment-and-mammographic-breast-density
#9
Parisa Tehranifar, Barbara A Cohn, Julie D Flom, Angeline Protacio, Piera Cirillo, L H Lumey, Karin B Michels, Mary Beth Terry
BACKGROUND: Early life social environment may influence breast cancer through shaping risk factors operating in early life, adolescence and adulthood, or may be associated with breast cancer risk independent of known risk factors. We investigated the associations between early life socioeconomic status (SES) and mammographic density, a strong risk factor for breast cancer, and the extent to which these associations were independent of risk factors across the lifecourse. METHODS: We used data from an adult follow-up study of two U...
January 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28064296/the-follow-up-of-post-mastectomy-patients-should-the-ipsilateral-side-be-assessed-with-both-mammogram-and-ultrasound
#10
S Radhika, B Hartini, A Norlia, M P Suria-Hayati, M A Zulfiqar
AIM: This study aimed to determine findings of axillary view mammogram (MMG) and ultrasound (USG) of the ipsilateral side in post-mastectomy patients and to document difficulty level in performing the axillary view and patients' pain level during the procedure. METHODS: Post-mastectomy patients who had MMG and USG on follow-up during an 18-months period were included. The MMG and USG findings of 183 patients were reviewed and histology results were recorded when available...
October 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28062399/longitudinal-study-of-mammographic-density-measures-that-predict-breast-cancer-risk
#11
Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Julie A Simpson, Gianluca Severi, Christopher Evans, Robert J MacInnis, Graham G Giles, Carmel Apicella, John L Hopper
BACKGROUND: After adjusting for age and body mass index (BMI), mammographic measures - dense area (DA), percent dense area (PDA) and non-dense area (NDA) - are associated with breast cancer risk. Our aim was to use longitudinal data to estimate the extent to which these risk-predicting measures track over time. METHODS: We collected 4,320 mammograms (age range, 24-83 years) from 970 women in the Melbourne Collaborative Cohort Study and the Australian Breast Cancer Family Registry...
January 6, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28058550/do-calcifications-seen-on-mammography-after-neoadjuvant-chemotherapy-for-breast-cancer-always-need-to-be-excised
#12
Yara Feliciano, Anita Mamtani, Monica Morrow, Michelle M Stempel, Sujata Patil, Maxine S Jochelson
BACKGROUND: This study aimed to determine the relationship between mammographic calcifications and magnetic resonance imaging (MRI) tumoral enhancement before and after neoadjuvant chemotherapy (NAC) and to assess the impact of these findings on surgical management. METHODS: This Institutional Review Board-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant retrospective study involved breast cancer patients who underwent NAC between 2009 and 2015...
January 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28055858/icap-an-individualized-model-combining-gaze-parameters-and-image-based-features-to-predict-radiologists-decisions-while-reading-mammograms
#13
Ziba Gandomkar, Kevin Tay, William Ryder, Patrick C Brennan, Claudia Mello-Thoms
This study introduces an individualized tool for identifying mammogram interpretation errors, called eye-Computer Assisted Perception (iCAP). iCAP consists of two modules, one which processes areas marked by radiologists as suspicious for cancer and classifies these as False Positive (FP) or True Positive (TP) decisions, while the second module classifies fixated but not marked locations as False Negative (FN) or True-Negative (TN) decisions. iCAP relies on both radiologists' gaze-related parameters, extracted from eye tracking data, and image-based features...
December 28, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28055247/-staging-of-breast-cancer-and-the-advanced-applications-of-digital-mammogram-what-the-physician-needs-to-know
#14
Maha Hussien Helal, Sahar Mahmoud Mansour, Mai Zaglol, Lamia Adel Salaleldin, Omniya Mokhtar Nada, Marwa Anas Haggag
OBJECTIVE: To study the role of advanced applications of digital mammogram whether contrast enhanced spectral mammography (CESM) or digital breast tomosynthesis (DBT) in the "T" staging of histologically proven breast cancer prior management planning. METHODS: This prospective analysis, we evaluated 98 proved malignant breast masses regarding their size, multiplicity and presence of associated clusters of microcalcifications. Evaluation methods included digital mammography, 3-D tomosynthesis and contrast enhanced spectral mammography...
January 5, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28053636/increased-malignant-microcalcifications-after-neoadjuvant-chemotherapy-in-advanced-breast-cancer
#15
Gi Won Shin, Young Mi Park, Hye Kyoung Yoon, Soo Jin Jung, Tae Hyun Kim, Anbok Lee, Seok Mo Lee
In patients with advanced breast cancer, most new calcifications detected on a mammogram after neoadjuvant chemotherapy are benign dystrophic calcifications, but this is not always observed. We present a patient with advanced breast cancer who had paradoxically increased malignant microcalcifications concomitant with primary tumor regression after undergoing neoadjuvant chemotherapy. After the neoadjuvant chemotherapy, the follow-up mammogram revealed that local, fine pleomorphic microcalcifications had markedly increased...
December 2016: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28052571/classification-of-normal-screening-mammograms-is-strongly-influenced-by-perceived-mammographic-breast-density
#16
Zoey Zy Ang, Mohammad A Rawashdeh, Rob Heard, Patrick C Brennan, Warwick Lee, Sarah J Lewis
INTRODUCTION: To investigate how breast screen readers classify normal screening cases using descriptors of normal mammographic features and to assess test cases for suitability for a single reading strategy. METHODS: Fifteen breast screen readers interpreted a test set of 29 normal screening cases and classified them by firstly rating their perceived difficulty to reach a 'normal' decision, secondly identifying the cases' salient normal mammographic features and thirdly assessing the cases' suitability for a single reading strategy...
January 3, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28050142/annual-surveillance-mammography-after-early-stage-breast-cancer-and-breast-cancer-mortality
#17
L F Paszat, R Sutradhar, S Gu, E Rakovitch
BACKGROUND: After treatment for early-stage breast cancer (bca), annual surveillance mammography (asm) is recommended based on the assumption that early detection of an invasive ipsilateral breast tumour recurrence or subsequent invasive contralateral primary bca reduces bca mortality. METHODS: We studied women with unilateral early-stage bca treated by breast-conserving surgery from 1994 to 1997 who subsequently developed an ipsilateral recurrence or contralateral primary more than 24 months after initial diagnosis, without prior regional or distant metastases...
December 2016: Current Oncology
https://www.readbyqxmd.com/read/28048397/we-de-207b-03-influence-of-local-anatomical-variations-on-detection-of-multifocal-and-multicentric-breast-cancer
#18
G Wen, M Markey, S Park
PURPOSE: We employed a novel model observer to assess the impact of local anatomic variations on the detection of multiple breast tumors depicted on mammograms. We expect the study to be valuable for future task-based assessments and optimizations of x-ray based breast imaging techniques (e.g., digital breast tomosynthesis for diagnosis of multifocal multicentric breast cancer (MMBC)). METHODS: Regions of interest (ROIs) from four different sets of clustered lumpy background simulations were extracted as the image background...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046518/tu-h-campus-iep2-04-efficient-binary-tree-description-of-high-resolution-breast-models-for-in-silico-imaging
#19
A Badal, C Graff, R Zeng, F Samuelson, A Badano
PURPOSE: We introduce a new geometric model for Monte Carlo (MC) simulation of breast tomosynthesis and mammography images with very high resolution digital breast phantoms voxelized at resolutions down to 50 microns or less. This fine sampling of the anatomy is required to reproduce the spiculated lesions and microcalcifications visible in clinical mammograms with pixel sizes under 100 microns. Phantoms voxelized at this resolution require such a large amount of computer memory that it might not be possible to execute the simulation in regular computers or in Graphics Processing Units (GPU), limiting the realism that can be achieved in virtual clinical trials...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046321/we-de-207b-02-detection-of-masses-on-mammograms-using-deep-convolutional-neural-network-a-feasibility-study
#20
S Suzuki, X Zhang, N Homma, K Ichiji, Y Kawasumi, T Ishibashi, M Yoshizawa
PURPOSE: To develop a deep convolutional neural network (DCNN)-based computer-aided diagnosis (CAD) system for detecting the masses in digital mammographic images. METHODS: A DCNN architecture, which consists of 5 convolutional layers and 3 fully connected layers, is constructed in this study. The DCNN parameters are then trained by the following two procedures. We first train the DCNN using about 1.3 million natural images for classification of 1,000 categories...
June 2016: Medical Physics
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