Frederieke A J Gigase, Rebecca H Jessel, Elianna Kaplowitz, Natalie Boychuk, Sophie Ohrn, Erona Ibroci, Juliana Castro, Jezelle Lynch, Rushna Tubassum, Amy Balbierz, Nina M Molenaar, Mara Graziani, Roy Missall, Tammy Flores, Toni Stern, Juan Manuel Carreno, Florian Krammer, Alan Adler, Rachel I Brody, Corina Lesseur, Jia Chen, Sascha Ellington, Romeo R Galang, Margaret C Snead, Elizabeth Howell, Joanne Stone, Veerle Bergink, Siobhan Dolan, Whitney Lieb, Anna-Sophie Rommel, Lotje D de Witte, Teresa Janevic
Associations between antenatal SARS-CoV-2 infection and pregnancy outcomes have been conflicting and the role of the immune system is currently unclear. This prospective cohort study investigated the interaction of antenatal SARS-CoV-2 infection, changes in cytokine and HS-CRP levels, birthweight and gestational age at birth. 2352 pregnant participants from New York City (2020-2022) were included. Plasma levels of interleukin (IL)-1β, IL-6, IL-17A and high-sensitivity C-reactive protein (HS-CRP) were quantified in blood specimens obtained across pregnancy...
March 18, 2024: Journal of Reproductive Immunology