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https://www.readbyqxmd.com/read/29772222/outcomes-of-laser-in-situ-keratomileusis-and-photorefractive-keratectomy-in-patients-taking-isotretinoin
#1
Julio Ortega-Usobiaga, Fernando Llovet-Osuna, Mohammad Reza Djodeyre, Rafael Bilbao-Calabuig, Félix González-López, Andrea Llovet-Rausell, Vasyl Druchkiv
PURPOSE: To determine the functional outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in patients taking isotretinoin, which is contraindicated for these procedures. DESIGN: Multicentre, retrospective, interventional case series METHODS: All patients taking isotretinoin who underwent LASIK or PRK from January 2003 to September 2017 were included (group 1). Patients were compared with those undergoing LASIK or PRK who had taken isotretinoin previously but not in the previous 6 months (group 2)...
May 14, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29753555/evaluation-of-early-postoperative-ocular-pain-after-photorefractive-keratectomy-and-corneal-crosslinking
#2
Siamak Zarei-Ghanavati, Soheyla Jafarpour, Alireza Radyn-Majd, Hamed Hosseinikhah-Manshadi
PURPOSE: To evaluate and compare early postoperative pain after photorefractive keratectomy (PRK) and corneal crosslinking (CXL). SETTING: Khatam-al-Anbia Eye Hospital, Mashhad, Iran. DESIGN: Prospective case series. METHODS: The PRK group included patients with simple refractive errors whereas the CXL group included patients with clinical keratoconus. The groups were compared regarding the level of pain based on the visual analogue scale (VAS), verbal rating scale (VRS), and Wong-Baker FACES pain rating scale immediately after surgery, 6 hours postoperatively, and 1, 3, and 7 days postoperatively...
May 9, 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29750010/comparative-analysis-of-safety-and-efficacy-of-photorefractive-keratectomy-versus-photorefractive-keratectomy-combined-with-crosslinking
#3
Gitansha Shreyas Sachdev, Shreyas Ramamurthy, Ramamurthy Dandapani
Purpose: To assess the safety, efficacy, and refractive predictability of half-fluence accelerated corneal collagen crosslinking (CXL) applied concurrently with photorefractive keratectomy (PRK), and compare the results to standard PRK. Setting: Refractive Services, The Eye Foundation, Coimbatore, India. Design: Interventional comparative case series. Methods: Patients seeking refractive correction for myopia or myopic astigmatism were included in the study...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29738586/retrospective-comparison-of-visual-outcomes-after-kamra-corneal-inlay-implantation-with-simultaneous-prk-or-lasik
#4
Majid Moshirfar, Andrew E Bean, Julio C Albarracin, Ronald L Rebenitsch, Ryan T Wallace, Orry C Birdsong
PURPOSE: To report a retrospective study of simultaneous LASIK versus photorefractive keratectomy (PRK) with accompanying small-aperture cornea inlay implantation (KAMRA; AcuFocus, Inc., Irvine, CA) in treating presbyopia. METHODS: Simultaneous LASIK/inlay and simultaneous PRK/inlay was performed on 79 and 47 patients, respectively. Follow-up examinations were conducted at 1, 3, and 6 months postoperatively. The main outcome measures were safety, efficacy, predictability, and stability with primary emphasis on monocular uncorrected near visual acuity (UNVA)...
May 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29732622/genetic-parameter-estimation-for-long-endurance-trials-in-the-uruguayan-criollo-horse
#5
R D López-Correa, F Peñagaricano, G Rovere, J I Urioste
The aim of this study was to estimate the genetic parameters of performance in a 750-km, 15-day ride in Criollo horses. Heritability (h2 ) and maternal lineage effects (mt2 ) were obtained for rank, a relative placing measure of performance. Additive genetic and maternal lineage (rmt) correlations among five medium-to-high intensity phase ranks (pRK) and final rank (RK) were also estimated. Individual records from 1,236 Criollo horses from 1979 to 2012 were used. A multivariate threshold animal model was applied to the pRK and RK...
May 7, 2018: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/29727516/interaction-between-adenylate-kinase-3-and-glyceraldehyde-3-phosphate-dehydrogenase-from-chlamydomonas-reinhardtii
#6
Yizhi Zhang, Hélène Launay, Fan Liu, Régine Lebrun, Brigitte Gontero
The critical and ubiquitous enzyme adenylate kinase (ADK) catalyzes the nucleotide phosphoryl exchange reaction: 2ADP ↔ ATP + AMP. The ADK3 in the chloroplasts of the green alga Chlamydomonas reinhardtii, bears an unusual C-terminal extension that is similar to the C-terminal end of the intrinsically disordered protein CP12. In this study, we report that this enzyme, when oxidized but not when reduced, is able to interact with the chloroplast glyceraldehyde-3-phosphate dehydrogenase (GAPDH) forming a stable complex as shown by native electrophoresis and mass spectrometry...
May 4, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29708926/pain-management-after-photorefractive-keratectomy
#7
Oren Golan, J Bradley Randleman
PURPOSE OF REVIEW: To review current concepts regarding the mechanisms of postoperative pain after photorefractive keratectomy (PRK) and review available treatment options. RECENT FINDINGS: Many clinical studies have established the safety and efficacy of different topical and systematic therapeutic agents and techniques for the treatment of postoperative pain after PRK, especially topical nonsteroidal anti inflammatory agents and oral nonsteroidal and narcotic medications...
April 27, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29704653/exceeding-the-theoretical-fermentation-yield-in-mixotrophic-rubisco-based-engineered-escherichia-coli
#8
I-Ting Tseng, Yi-Ling Chen, Ching-Hsun Chen, Zhi-Xuan Shen, Cheng-Han Yang, Si-Yu Li
Rubisco-based engineered Escherichia coli MZLFB (E. coli BL21(DE3) Δzwf, Δldh, Δfrd) containing heterologous phosphoribulokinase (Prk) and Ribulose-1,5- bisphosphate carboxylase/oxygenase (Rubisco) was constructed for the mixotrophic growth. However, in situ CO2 recycling was hindered by clogs of pyruvate during glucose metabolism, which consequently resulted in an insufficient regeneration of NAD+ through the pflB-mediated ethanol production. Recombinant plasmid pLOI295 (encodes pyruvate decarboxylase and alcohol dehydrogenase II, referred to as the Pdc-based carbon tap valve (CTV) for convenience) was introduced into E...
April 25, 2018: Metabolic Engineering
https://www.readbyqxmd.com/read/29703289/ability-of-a-new-crosslinked-polymer-ocular-bandage-gel-to-accelerate-reepithelialization-after-photorefractive-keratectomy
#9
Daniel S Durrie, Darcy Wolsey, Vance Thompson, Carol Assang, Brenda Mann, Barbara Wirostko
PURPOSE: To evaluate the safety and performance of a crosslinked thiolated carboxymethyl hyaluronic acid liquid-gel (CMHA-S) ocular bandage gel in accelerating reepithelialization of corneal defects created for photorefractive keratectomy (PRK). SETTING: Three community-based clinical research sites. DESIGN: Prospective case series. METHODS: Patients scheduled for bilateral PRK had both eyes randomized immediately after PRK to Group 1 (ocular bandage gel 4 times a day for 14 days and bandage contact lens), Group 2 (ocular bandage gel 4 times a day for 14 days), or Group 3 (control; bandage contact lens and artificial tears 4 times a day for 14 days)...
March 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29675379/photorefractive-keratectomy-after-cataract-surgery-in-uncommon-cases-long-term-results
#10
Anna Maria Roszkowska, Mario Urso, Giuseppe Alberto Signorino, Leopoldo Spadea, Pasquale Aragona
AIM: To evaluate the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with intraocular lens (IOL) implantation in uncommon cases. METHODS: Totally 24 patients with high residual refractive error after cataract surgery with IOL implantation were examined. Twenty-two patients had a history of phacoemulsification and IOL implantation, and two had extra-capsular cataract extraction with IOL implantation...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29644238/mechanisms-of-optical-regression-following-corneal-laser-refractive-surgery-epithelial-and-stromal-responses
#11
REVIEW
Majid Moshirfar, Jordan D Desautels, Brian D Walker, Michael S Murri, Orry C Birdsong, Phillip C Hoopes
Laser vision correction is a safe and effective method of reducing spectacle dependence. Photorefractive Keratectomy (PRK), Laser In Situ Keratomileusis (LASIK), and Small-Incision Lenticule Extraction (SMILE) can accurately correct myopia, hyperopia, and astigmatism. Although these procedures are nearing optimization in terms of their ability to produce a desired refractive target, the long term cellular responses of the cornea to these procedures can cause patients to regress from the their ideal postoperative refraction...
2018: Medical Hypothesis, Discovery and Innovation in Ophthalmology
https://www.readbyqxmd.com/read/29610222/two-year-follow-up-of-corneal-cross-linking-and-refractive-surface-ablation-in-patients-with-asymmetric-corneal-topography
#12
João Baptista N S Malta, H Kaz Soong, Bernardo Kaplan Moscovici, Mauro Campos
AIMS: To evaluate the safety and efficacy of corneal cross-linking (CXL) followed by photorefractive keratectomy (PRK) for refractive correction in patients with bilateral asymmetric topography. METHODS: Forty-four patients (88 eyes) were enrolled in this prospective randomised clinical trial. CXL with subsequent PRK after 6 months was performed in one eye (study group), and PRK alone was performed in contralateral eyes (control group). Patients were followed for 24 months after PRK...
April 2, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29610024/topography-guided-transepithelial-photorefractive-keratectomy-to-correct-irregular-refractive-errors-after-radial-keratotomy
#13
Mohammad Ghoreishi, Alireza Peyman, Nima Koosha, Khodayar Golabchi, Mohsen Pourazizi
PURPOSE: To evaluate the efficacy and safety of topography-guided transepithelial photorefractive keratectomy (PRK) in a group of patients with post-radial keratotomy (RK) showing irregular corneas. SETTING: Feiz University Hospital, Isfahan, Iran. DESIGN: Prospective case series. METHODS: Consecutive patients who had irregular astigmatism after RK with stable refraction and topography for at least 1 year were recruited...
March 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29607215/calculation-of-unknown-preoperative-k-readings-in-postrefractive-surgery-patients
#14
Nicola Rosa, Maddalena De Bernardo, Maria Borrelli
Purpose: To determine the unknown preoperative K readings (Kpre) to be used in history-based methods, for intraocular lens (IOL) power calculation in patients who have undergone myopic photorefractive keratectomy (PRK). Methods: A regression formula generated from the left eyes of 174 patients who had undergone PRK for myopia or for myopic astigmatism was compared with other methods in 168 right eyes. The Pearson index and paired t -test were utilized for statistical analysis...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29564408/two-year-results-of-femtosecond-assisted-lasik-versus-prk-for-different-severity-of-astigmatism
#15
Mohammad Miraftab, Hassan Hashemi, Soheila Asgari
Purpose: To compare two-year results of femtosecond laser assisted LASIK (femto-LASIK) and photorefractive keratectomy (PRK) in terms of astigmatism correction in patients with less than 2.0 diopters (D) of spherical error and more than 2.0 D of cylinder error. Methods: In this retrospective study, data were extracted from 100 patient charts. The two study groups were matched by age, gender, and baseline uncorrected distance visual acuity (UDVA) and refractive astigmatism (RA)...
March 2018: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/29561408/keratectasia-after-laser-assisted-subepithelial-keratectomy-for-myopia-a-case-report
#16
Qinghong Lin, Lin Zheng, Xiumei Lin, Qian Wang
RATIONALE: Recently, some ophthalmologists performed PRK or LASEK surgeries in FFKC suspicious patients, which is supposed to prevent FFKC evolvement via fibrotic scar formation. Our report indicates that keratectasia can occur after LASEK in FFKC suspicious patients, highlighting the importance of stricter regulation of patient recruitment before the procedure and postoperative follow-up. PATIENT CONCERNS: This is a report of a 25-year-old man with poor corrected distance visual acuity (CDVA) 6 years after LASEK...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29532217/z-lasik-and-trans-prk-for-correction-of-high-grade-myopia-safety-efficacy-predictability-and-clinical-outcomes
#17
Assaf Gershoni, Michael Mimouni, Eitan Livny, Irit Bahar
PURPOSE: The aim of the study was to examine the outcomes of transepithelial photorefractive keratectomy (Trans-PRK) and Femtosecond Laser-assisted in situ keratomileusis (Z-LASIK) for the correction of high myopia. METHODS: A retrospective cohort study design was used. The study group included 792 eyes with high-grade myopia (- 6.0 diopters or higher) or high-grade myopia with astigmatism that were treated with Z-LASIK or Trans-PRK in 2013 through 2014 in an optical outpatient clinic of a large private medical service...
March 12, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29522226/nepafenac-ophthalmic-suspension-0-3-for-the-management-of-ocular-pain-after-photorefractive-keratectomy
#18
George A Kontadakis, Konstantina G Chronopoulou, Rodoula Tsopouridou, David Tabibian, George D Kymionis
PURPOSE: To investigate the effect of nepafenac 0.3% in a once daily dosage regarding pain and healing after photorefractive keratectomy (PRK). METHODS: This was a prospective, comparative, contralateral randomized study of 35 patients undergoing PRK for the correction of low to moderate myopia and myopic astigmatism. After randomization, patients received nepafenac 0.3% ophthalmic suspension once daily in one eye (nepafenac 0.3% group) and nepafenac 0.1% ophthalmic suspension three times a day in the other eye (nepafenac 0...
March 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29522224/clinical-outcomes-of-smile-with-a-triple-centration-technique-and-corneal-wavefront-guided-transepithelial-prk-in-high-astigmatism
#19
Ikhyun Jun, David Sung Yong Kang, Dan Z Reinstein, Samuel Arba-Mosquera, Timothy J Archer, Kyoung Yul Seo, Tae-Im Kim
PURPOSE: To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photorefractive keratectomy (PRK) for the correction of high astigmatism. METHODS: This retrospective, comparative case series study included 89 eyes (89 patients) that received treatment for myopia with high astigmatism (≥ 2.50 diopters) using SMILE with a triple centration technique (SMILE group; 45 eyes) and corneal wavefront-guided transepithelial PRK (transepithelial PRK group; 44 eyes)...
March 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29502213/photorefractive-keratectomy-influences-the-angle-of-ocular-deviation-in-strabismus-patients-with-hyperopia
#20
Giuseppe Giannaccare, Laura Primavera, Michela Fresina
PURPOSE: To evaluate refractive, binocular vision and ocular alignment outcomes of photorefractive keratectomy (PRK) for the treatment of hyperopia in esotropic patients. METHODS: Medical charts of hyperopic patients with full or partial accommodative esotropia (FAE or PAE) or consecutive exotropia (CE) undergone PRK from 2011 to 2014 were reviewed. The primary outcome was to assess the efficacy of PRK in improving ocular alignment. The secondary outcomes were the assessments of uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), spherical equivalent (SE) and stereoacuity...
March 3, 2018: International Ophthalmology
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