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https://www.readbyqxmd.com/read/29353142/mirna-185-regulates-the-vegfa-signaling-pathway-in-dairy-cows-with-retained-fetal-membranes
#1
REVIEW
C Y Zheng, X Zou, H J Lin, B C Zhao, M L Zhang, C H Luo, S X Fu
Retention of fetal membranes (RFM) of cows is an important reproductive disturbance, and is related to miRNAs. Vascular endothelial growth factor (VEGF)A, regulated by miRNA-185, can activate arachidonic acid (ARA) release via the VEGFA signaling pathway, which influences RFM. The aim of this study was to explore the pathogenic mechanism of RFM by investigating the regulatory relationship between miRNA-185 and the VEGFA signaling pathway. Serum samples of healthy Holstein dairy cows (n = 20) and RFM cows (n = 12), with a similar age, parity, weight, and milk yield, were collected to detect VEGFA and ARA concentrations at 6, 12, and 24 h after calving...
January 9, 2018: Theriogenology
https://www.readbyqxmd.com/read/29340891/mitomycin-c-0-02-and-0-002-efficacy-in-preventing-haze-after-photorefractive-keratectomy
#2
L M Coelho, R O Sieiro
PURPOSE: To compare MMC 0.002% efficacy in preventing haze after PRK in relation to MMC 0.02%. PATIENTS AND METHODS: We conducted a prospective study with patients with myopia or myopic astigmatism undergoing PRK in the same conditions. After PRK, MMC was applied for 30 s in a concentration of 0.02% on the right eye (group 1) and 0.002% on the left eye (group 2). Age, gender, spherical equivalent and haze intensity (1, 3, 6 and 12 months postoperatively) were assessed...
January 16, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29339637/corneal-collagen-crosslinking-combined-with-phototherapeutic-keratectomy-and-photorefractive-keratectomy-for-corneal-ectasia-after-laser-in-situ-keratomileusis
#3
Wei Zhu, Yunfei Han, Changxia Cui, Wenwen Xu, Xuan Wang, Xiaoxiao Dou, Linlin Xu, Yanyun Xu, Guoying Mu
PURPOSE: The aim of this study was to analyze the effects of corneal crosslinking (CXL) combined with phototherapeutic keratectomy (PTK) and photorefractive keratectomy (PRK) in halting the progression and improving the visual function of corneal ectasia after laser in situ keratomileusis (LASIK). METHODS: PTK-PRK-CXL was performed on 14 eyes of 14 patients who developed corneal ectasia after LASIK. The visual acuity, spherical refraction and cylinder, corneal topography indices, thinnest corneal thickness (TCT), and endothelial cell count were evaluated at baseline and at 1, 3, 6, and 12 months postoperatively...
January 17, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29339065/accommodative-esotropia-treatment-plan-utilizing-simultaneous-strabismus-surgery-and-photorefractive-keratectomy
#4
H Sprague Eustis, Pulin Shah
PURPOSE: Accommodative esotropia is a common cause of acquired esotropia. Pathogenesis varies among patients but usually includes excessive hyperopia and a high accommodative convergence/accommodation ratio or tight medial recti. The present study reviews an individualized treatment plan combining photorefractive keratectomy (PRK) and strabismus surgery to correct these problems. DESIGN: This study is a retrospective, interventional case series. METHODS: Records for 15 patients who were treated for accommodative esotropia were reviewed...
January 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29335097/aspheric-versus-wavefront-guided-aspheric-photorefractive-keratectomy-in-eyes-with-significant-astigmatism
#5
Amir Faramarzi, Majid Moshirfar, Farid Karimian, Siamak Delfazayebaher, Bahareh Kheiri
PURPOSE: To compare the refractive and higher-order aberrations (HOAs) outcomes after photorefractive keratectomy (PRK) in patients with significant astigmatism using aspheric versus wavefront-guided aspheric profiles. SETTING: Ophthalmic Research Center and Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Negah Eye Hospital, Tehran, Iran. DESIGN: Prospective randomized case series. METHODS: One eye of each patient with a refractive astigmatism more than 2...
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29335093/changes-in-biomechanically-corrected-intraocular-pressure-and-dynamic-corneal-response-parameters-before-and-after-transepithelial-photorefractive-keratectomy-and-femtosecond-laser-assisted-laser-in%C3%A2-situ-keratomileusis
#6
Hun Lee, Cynthia J Roberts, Tae-Im Kim, Renato Ambrósio, Ahmed Elsheikh, David Sung Yong Kang
PURPOSE: To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser-assisted laser in situ keratomileusis (LASIK). SETTING: Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. DESIGN: Retrospective case series. METHODS: Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined...
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29315443/pathophysiology-of-corneal-scarring-in-persistent-epithelial-defects-after-prk-and-other-corneal-injuries
#7
Steven E Wilson, Carla S Medeiros, Marcony R Santhiago
PURPOSE: To analyze corneal persistent epithelial defects that occurred at 3 to 4 weeks after -4.50 diopter (D) photorefractive keratectomy (PRK) in rabbits and apply this pathophysiology to the treatment of persistent epithelial defects that occur after any corneal manipulations or diseases. METHODS: Two of 168 corneas that had -4.50 D PRK to study epithelial basement membrane regeneration developed spontaneous persistent epithelial defects that did not heal at 3 weeks after PRK...
January 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29283117/refractive-lenticule-extraction-small-incision-lenticule-extraction-a-new-refractive-surgery-paradigm
#8
REVIEW
Sri Ganesh, Sheetal Brar, Raghavender Reddy Arra
Small incision lenticule extraction (SMILE), a variant of refractive lenticule extraction technology is becoming increasingly popular, as a flapless and minimally invasive form of laser vision correction (LVC) for the treatment of myopia and myopic astigmatism. This review aims at summarizing the principles, surgical technique, and clinical outcomes in terms of visual and refractive results, safety, efficacy, postoperative dry eye, aberrations, and biomechanics of SMILE and its comparison with other conventional techniques of LVC, such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK)...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29227512/efficacy-and-safety-comparison-between-suberoylanilide-hydroxamic-acid-and-mitomycin-c-in-reducing-the-risk-of-corneal-haze-after-prk-treatment-in-vivo
#9
Govindaraj Anumanthan, Ajay Sharma, Michael Waggoner, Chuck W Hamm, Suneel Gupta, Nathan P Hesemann, Rajiv R Mohan
PURPOSE: This study compared the efficacy and safety of suberoylanilide hydroxamic acid (SAHA) and mitomycin C (MMC) up to 4 months in the prevention of corneal haze induced by photorefractive keratectomy (PRK) in rabbits in vivo. METHODS: Corneal haze in rabbits was produced with -9.00 diopter PRK. A single application of SAHA (25 μM) or MMC (0.02%) was applied topically immediately after PRK. Effects of the two drugs were analyzed by slit-lamp microscope, specular microscope, TUNEL assay, and immunofluorescence...
December 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29227510/postoperative-corneal-asphericity-in-low-moderate-and-high-myopic-eyes-after-transepithelial-prk-using-a-new-pulse-allocation
#10
David T C Lin, Simon P Holland, Shwetabh Verma, John Hogden, Samuel Arba-Mosquera
PURPOSE: To evaluate the postoperative asphericity in low, moderate, and high myopic eyes after combined transepithelial photorefractive keratectomy and SmartSurfACE treatment (SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany). METHODS: In this retrospective case series, the outcomes of myopic SmartSurfACE were evaluated at 3 months postoperatively in 106 eyes and divided into low (less than -4.125 diopters [D]), moderate (-4.125 to -6.25 D), and high (more than -6...
December 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29215394/visual-outcomes-and-aberrometric-changes-with-topography-guided-photorefractive-keratectomy-treatment-of-irregular-astigmatism-after-penetrating-keratoplasty
#11
Francisco Bandeira E Silva, Rossen Mihaylov Hazarbassanov, Eduardo Martines, José Luis Güell, Ana L Hofling-Lima
PURPOSE: To evaluate the visual acuity and keratometric and aberrometric changes in patients with corneal transplants (PKP), who underwent topography-guided photorefractive keratectomy (TG-PRK) with mitomycin C (MMC). METHODS: In this case study, 15 patients with spherical equivalents ranging from -11.00 to -0.25 diopters (D) who underwent penetrating corneal transplantation and had irregular astigmatism ranging from -7.5 to -2.0 D underwent TG-PRK with MMC. Corneal topography and wavefront of all patients were measured preoperatively and 12 months postoperatively...
December 5, 2017: Cornea
https://www.readbyqxmd.com/read/29120711/combined-transepithelial-phototherapeutic-keratectomy-and-conventional-photorefractive-keratectomy-followed-simultaneously-by-corneal-crosslinking-for-keratoconus-cretan-protocol-plus
#12
Michael A Grentzelos, George A Kounis, Vasilios F Diakonis, Charalambos S Siganos, Miltiadis K Tsilimbaris, Ioannis G Pallikaris, George D Kymionis
PURPOSE: To evaluate the visual, refractive, and topographic outcomes after combined transepithelial phototherapeutic keratectomy (PTK) and conventional photorefractive keratectomy (PRK) followed simultaneously by corneal crosslinking (CXL) for keratoconus. SETTING: Vardinoyiannion Eye Institute of Crete, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece. DESIGN: Prospective case series. METHODS: Patients with progressive keratoconus had simultaneous conventional PRK followed by CXL; the corneal epithelium was removed using transepithelial PTK (Cretan protocol plus)...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29119072/a-comparison-of-visual-outcomes-and-patient-satisfaction-between-photorefractive-keratectomy-and-femtosecond-laser-assisted-in-situ-keratomileusis
#13
Nauman Hashmani, Sharif Hashmani, Priyanka Ramesh, Hina Rajani, Junaid Ahmed, Jaish Kumar, Arun Kumar, Munira Jamali
Purpose To compare visual outcomes and satisfaction among patients of photorefractive keratectomy (PRK; Wavelight EX 500, Alcon, Ft Worth, TX, USA) and femtosecond laser-assisted in situ keratomileusis (FAL; Wavelight FS 200 laser and Wavelight EX 500, Alcon, Ft Worth, TX, USA). Methods We performed a retrospective study of 409 eyes in 207 patients that underwent either PRK (n=90) or FAL (n=117) at the two centers of Hashmanis Hospital, Karachi, Pakistan. The included refractive outcomes were sphere diopters (D), cylinder D, and spherical equivalent D...
September 1, 2017: Curēus
https://www.readbyqxmd.com/read/29117422/erratum-for-mathematical-model-to-compare-the-relative-tensile-strength-of-the-cornea-after-prk-lasik-and-small-incision-lenticule-extraction
#14
(no author information available yet)
No abstract text is available yet for this article.
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29090046/preparation-and-thickness-profile-of-endothelial-keratoplasty-lenticules-from-donated-whole-eyes-with-previous-photorefractive-keratectomy
#15
Mozhgan Rezaei Kanavi, Pejman Fahim, Mohsen Rahmanian, Tahereh Chamani, Bahar Kheiri, Sahar Balagholi, Mohammad Ali Javadi
PURPOSE: To describe the preparation and thickness profiles of endothelial keratoplasty lenticules harvested from eyes with previous photorefractive keratectomy (PRK). METHODS: Donor whole eyes that underwent PRK were subjected to microkeratome-assisted dissection for Descemet stripping automated endothelial keratoplasty. Specular microscopy and Visante optical coherence tomography were performed on precut corneas. Endothelial cell indices and thickness profiles of endothelial keratoplasty lenticules were statistically analyzed...
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29090045/comparison-between-pentacam-hr-and-orbscan-ii-after-hyperopic-photorefractive-keratectomy
#16
Mahmoud Jabbarvand, Farshad Askarizadeh, Mohamad Reza Sedaghat, Hadi Ghadimi, Bahram Khosravi, Mohammad Aghazadeh Amiri, Foroozan Narooie-Noori
PURPOSE: The aim of this study was to determine the agreement between Pentacam HR (Scheimpflug imaging, Oculus) and Orbscan II (scanning slit topography, Bausch and Lomb) in measuring corneal parameters after photorefractive keratectomy (PRK) for hyperopia. METHODS: In this prospective cross-sectional study, 38 hyperopic eyes undergoing PRK were examined before refractive surgery and 8 to 10 months postoperatively using Pentacam HR and Orbscan II. Ultrasound (US) pachymetry was also used to measure central corneal thickness (CCT)...
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29066773/biomechanical-simulation-of-stress-concentration-and-intraocular-pressure-in-corneas-subjected-to-myopic-refractive-surgical-procedures
#17
Po-Jen Shih, I-Jong Wang, Wen-Feng Cai, Jia-Yush Yen
Recent advances in the analysis of corneal biomechanical properties remain difficult to predict the structural stability before and after refractive surgery. In this regard, we applied the finite element method (FEM) to determine the roles of the Bowman's membrane, stroma, and Descemet's membrane in the hoop stresses of cornea, under tension (physiological) and bending (nonphysiological), for patients who undergo radial keratotomy (RK), photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis (LASIK), or small incision lenticule extraction (SMILE)...
October 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29053556/epithelial-erosions-and-refractive-results-after-single-step-transepithelial-photorefractive-keratectomy-and-alcohol-assisted-photorefractive-keratectomy-in-myopic-eyes-a-comparative-evaluation-over-12-months
#18
Maamoun A Fattah, Rafic Antonios, Sam Arba Mosquera, Bachir Abiad, Shady T Awwad
PURPOSE: To evaluate the epithelial erosion incidence and refractive results in myopic eyes undergoing single-step transepithelial photorefractive keratectomy (TransPRK) compared with alcohol-assisted photorefractive keratectomy (PRK). METHODS: This was a retrospective nonrandomized comparative study conducted at the American University of Beirut Medical Center. A total of 189 eyes that had undergone single-step transepithelial PRK (TransPRK) were compared with 189 matched eyes that had undergone alcohol-assisted PRK over a follow-up of 1 year...
October 17, 2017: Cornea
https://www.readbyqxmd.com/read/29042748/corneal-biomechanical-properties-after-laser-assisted-in-situ-keratomileusis-and-photorefractive-keratectomy
#19
Eileen S Hwang, Brian C Stagg, Russell Swan, Carlton R Fenzl, Molly McFadden, Valliammai Muthappan, Luis Santiago-Caban, Mark D Mifflin, Majid Moshirfar
BACKGROUND: The purpose of this study was to evaluate the effects of laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) on corneal biomechanical properties. METHODS: We used the ocular response analyzer to measure corneal hysteresis (CH) and corneal resistance factor (CRF) before and after refractive surgery. RESULTS: In all, 230 eyes underwent LASIK and 115 eyes underwent PRK without mitomycin C (MMC). Both procedures decreased CH and CRF from baseline...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29042747/high-resolution-wavefront-guided-surface-ablation-with-corneal-cross-linking-in-ectatic-corneas-a-pilot-study
#20
Gustavo E Tamayo, Claudia Castell, Pilar Vargas, Eduardo Polania, Juliana Tamayo
PURPOSE: A preliminary study to evaluate the outcomes of high-resolution wavefront-guided (HRWG) photorefractive keratectomy (PRK) with simultaneous corneal cross-linking (CXL) in ectasia eyes. METHODS: Sixteen eyes of 11 patients (mean age 31.9±9.8 years; range: 15-48 years) with keratoconus or post-laser-assisted in situ keratomileusis ectasia underwent HRWG PRK with simultaneous CXL. Manifest refraction, uncorrected (UDVA) and corrected distance visual acuity (CDVA), and keratometric and aberrometric outcomes are reported at 12 months...
2017: Clinical Ophthalmology
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