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https://www.readbyqxmd.com/read/28160608/is-there-evidence-for-a-surgeon-learning-curve-for-endothelial-keratoplasty-in-australia
#1
Miriam C Keane, Richard Ad Mills, Douglas J Coster, Keryn A Williams
IMPORTANCE: Expected outcomes from endokeratoplasty may vary with surgeon experience. BACKGROUND: We explored whether a surgeon learning curve exists for Descemet stripping endothelial keratoplasties (manual or automated) performed in Australia. DESIGN: Prospective cohort study; various clinical settings. PARTICIPANTS: 2139 recipients of 2615 endothelial grafts, registered by 85 surgeons between January 2006 and December 2013...
February 4, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28149669/survey-of-experts-on-current-endothelial-keratoplasty-techniques
#2
Winston Chamberlain, Ariana Austin, Mark Terry, Bennie H Jeng, Jennifer Rose-Nussbaumer
OBJECTIVE: To survey cornea specialists' opinions on different endothelial keratoplasty techniques and to gauge the perceived need for and utility of a randomized controlled trial (RCT) comparing them. METHODS: A short survey was distributed to a group of cornea specialists at the Endothelial Keratoplasty Group meeting at the American Academy of Ophthalmology meeting in November 2015. RESULTS: Thirty-three of 80 practicing surgeons present at the EKG meeting participated in the survey, yielding a response rate of 41%...
October 2016: Journal of Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28114585/immune-cells-on-the-corneal-endothelium-of-an-allogeneic-corneal-transplantation-rabbit-model
#3
Elena Koudouna, Naoki Okumura, Yugo Okazaki, Shinichiro Nakano, Ryota Inoue, Nigel J Fullwood, Junko Hori, Shigeru Kinoshita, Noriko Koizumi
Purpose: Corneal endothelial cell density undergoes a progressive decrease for many years after transplantation, eventually threatening patients with late endothelial failure. The purpose of this study was to investigate the possibility of an immunologic response in successfully grafted corneal endothelium. Methods: The corneal endothelium of patients who had undergone corneal transplantation was evaluated by specular microscopy. Rabbit models were subjected to penetrating keratoplasty (PK) with either syngeneic or allogeneic corneal transplants and Descemet's stripping endothelial keratoplasty (DSEK) with allogeneic corneal transplants...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28018708/clinical-outcomes-of-descemet-membrane-endothelial-keratoplasty-during-the-surgeon-learning-curve-versus-descemet-stripping-endothelial-keratoplasty-performed-at-the-same-time
#4
Jennifer Rose-Nussbaumer, Shashi Alloju, Winston Chamberlain
PURPOSE: To compare outcomes after Descemet Membrane Endothelial Keratoplasty (DMEK) and traditional Descemet Stripping Endothelial Keratoplasty (DSEK) during the surgeon's DMEK learning curve in a prospective, non-randomized, consecutive, interventional case series. METHODS: Consecutive patients presenting to the university eye clinics and undergoing endothelial keratoplasty were included. Data including patient demographics, visual acuity, endothelial cell counts and complications were recorded at baseline, as well as 3 and 6 months post-operatively...
October 2016: Journal of Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27994805/descemet-s-membrane-endothelial-keratoplasty-in-south-asian-population
#5
Vipul Bhandari, Jagdeesh K Reddy, Prateek Chougale
PURPOSE: To evaluate visual outcomes, endothelial cell density and complications following Descemet's membrane endothelial keratoplasty (DMEK). METHODS: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured and compared before and 6 months after surgery. RESULTS: Out of 40 eyes, 34 eyes (85%) had BCVA ranging from 0...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27658681/clinical-characterization-of-posterior-polymorphous-corneal-dystrophy-in-patients-of-indian-ethnicity
#6
Sunita Chaurasia, Rashmi Mittal, G Bichappa, Muralidhar Ramappa, Somasheila I Murthy
PURPOSE: To characterize the clinical presentation of posterior polymorphous corneal dystrophy (PPCD) in eyes of Indian ethnicity. DESIGN: Retrospective cohort study from January 1995 to December 2015. PARTICIPANTS: Patients with the diagnosis of posterior polymorphous corneal dystrophy. METHODS: Medical records of the patients were reviewed for clinical presentation. Histology of corneal specimens of those that underwent keratoplasty was assessed...
September 22, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27633840/influence-of-early-descemet-stripping-endothelial-keratoplasty-on-visual-outcomes-in-pseudophakic-corneal-edema
#7
Sarah B Weissbart, Kristin M Hammersmith, Brandon D Ayres, Christopher J Rapuano, Parveen K Nagra, Irving M Raber, Amir A Azari
PURPOSE: Long-standing corneal edema can lead to anterior stromal scarring that may limit visual acuity following Descemet stripping endothelial keratoplasty (DSEK). The ideal time to perform DSEK to prevent permanent changes is unclear. Our aim is to determine whether earlier DSEK is associated with improved visual outcomes. DESIGN: Cohort study. METHODS: Setting: Institutional. STUDY POPULATION: 120 eyes of patients who underwent DSEK for corneal edema following cataract surgery (CE)...
September 12, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27429090/intraocular-lens-calcification-after-dsek-a-mechanism-and-preventive-technique
#8
Joseph C Lacey, Baljit K Ghatora, Peter J S Foot, Stephen J Barton, Romain De Cock
No abstract text is available yet for this article.
September 2016: Cornea
https://www.readbyqxmd.com/read/27413563/combined-dsek-and-transconjunctival-pars-plana-vitrectomy
#9
Mona Sane, Naazli Shaikh, Saad Shaikh
We report here three patients who underwent combined Descemet's stripping with endothelial keratoplasty and transconjunctival pars plana vitrectomy for bullous keratopathy and posterior segment pathology. A surgical technique and case histories are described. Anatomic and visual outcomes of combined Descemet's stripping with endothelial keratoplasty and vitrectomy were excellent. Our experience provides technical guidelines and limitations. The combined minimally invasive techniques allow for rapid anatomical recovery and return of function and visual acuity in a single sitting...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27108095/descemet-stripping-endothelial-keratoplasty-ten-year-endothelial-cell-loss-compared-with-penetrating-keratoplasty
#10
Marianne O Price, Peter Calhoun, Craig Kollman, Francis W Price, Jonathan H Lass
PURPOSE: To assess endothelial cell density (ECD) and model 10-year cell loss after Descemet stripping endothelial keratoplasty (DSEK), and to compare with results after penetrating keratoplasty (PK) performed for the same indications in the Cornea Donor Study (CDS). DESIGN: Retrospective, longitudinal study. PARTICIPANTS: Five hundred ninety DSEK recipients, 21 to 96 years of age, treated for Fuchs' dystrophy (n = 498; 84%), pseudophakic or aphakic corneal edema (n = 89; 15%), or other endothelial dysfunction (n = 3; <1%)...
July 2016: Ophthalmology
https://www.readbyqxmd.com/read/27055220/endothelial-cell-loss-after-needle-push-insertion-descemet-stripping-endothelial-keratoplasty-dsek
#11
Edward J Casswell, Oliver Bowes, Allon Barsam, Henry D Perry
No abstract text is available yet for this article.
June 2016: Cornea
https://www.readbyqxmd.com/read/26979114/-preliminary-results-of-femtosecond-laser-assisted-descemet-stripping-endothelial-keratoplasty-for-bullous-keratopathy
#12
G F Huang, Y Gao, X J Charlotte Aimee, G B Liao, Y J Xiao, X Li, S Y Shi, Shiyou Zhou
OBJECTIVE: To evaluate the preliminary results of femtosecond laser-assisted Descemet stripping endothelial keratoplasty (FS-DSEK) for the treatment of bullous keratopathy. METHODS: In the nonrandomized, prospective, consecutive case series, 7 eyes with bullous keratopathy induced by cataract surgery received FS-DSEK surgery between September and December 2013. Standard Descemet stripping endothelial keratoplasty procedure was performed. The Descemet membrane and abnormal endothelial layer were stripped from the central recipient posterior surface in a diameter of 7...
March 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/26874154/comparison-of-intraocular-pressure-post-penetrating-keratoplasty-vs-descemet-s-stripping-endothelial-keratoplasty
#13
COMPARATIVE STUDY
Rahul A Sharma, Lulu L C D Bursztyn, Elizabeth Golesic, Rookaya Mather, David P Tingey
OBJECTIVE: To compare the effect of Descemet's stripping endothelial keratoplasty (DSEK) with penetrating keratoplasty (PKP) on intraocular pressure (IOP) and use of ocular antihypertensives. DESIGN: Retrospective cohort study. PARTICIPANTS: Thirty-five eyes in 33 patients undergoing PKP and 43 eyes in 38 patients undergoing DSEK were included in the analysis. Fifteen eyes undergoing PKP and 12 undergoing DSEK had diagnosed glaucoma. Patients undergoing corneal transplant because of trauma, keratoconus, pellucid marginal degeneration, or prior failed transplant were excluded...
February 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/26731973/graft-stability-after-endothelial-keratoplasty
#14
Vesna Jovanović, Ljubisa Nikolić
UNLABELLED: BACGROUND/AIM: Techniques for replacing the corneal endothelium have been improved. The host-graft interface is the key to graft adhesion and visual recovery. The aim of this study was to establish graft stability after Descemet stripping with endothelial keratoplasty (DSEK), compare it to the graft stability after endothelial keratoplasty with the intact posterior corneal layers (nDSEK) in the rabbit cornea, and to investigate the nature of wound healing. METHODS: Adult white rabbits (n = 20) were divided in two experimental groups: ten rabbits underwent monocular DSEK, and ten rabbits underwent endothelial keratoplasty without Descemet stripping (nDSEK)...
November 2015: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/26708363/determinants-of-visual-quality-after-endothelial-keratoplasty
#15
REVIEW
Andrew M J Turnbull, Michael Tsatsos, Parwez N Hossain, David F Anderson
Endothelial keratoplasty is now favored over full-thickness penetrating keratoplasty for corneal decompensation secondary to endothelial dysfunction. Although endothelial keratoplasty has evolved as surgeons strive to improve outcomes, fewer patients than expected achieve best corrected visual acuity of 20/20 despite healthy grafts and no ocular comorbidities. Reasons for this remain unclear, with theories including anterior stromal changes, differences in graft thickness and regularity, induced high-order aberrations, and the nature of the graft-host interface...
May 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/26707032/effect-of-graft-thickness-on-visual-acuity-after-descemet-stripping-endothelial-keratoplasty-a-systematic-review-and-meta-analysis
#16
REVIEW
Katrin Wacker, William M Bourne, Sanjay V Patel
PURPOSE: To assess the relationship between graft thickness and best-corrected visual acuity (BCVA) after Descemet stripping endothelial keratoplasty (DSEK). DESIGN: Systematic review and meta-analysis. METHODS: PubMed, EMBASE, Web of Science, and conference abstracts were searched for studies published up to October 2015 with standard systematic review methodology. Eligibility criteria included studies evaluating graft thickness in primary DSEK and visual outcomes...
March 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/26636101/descemet-s-stripping-automated-endothelial-keratoplasty-versus-descemet-s-membrane-endothelial-keratoplasty-in-the-fellow-eye-for-fuchs-endothelial-dystrophy-a-retrospective-study
#17
COMPARATIVE STUDY
Vipul Bhandari, Jagdeesh K Reddy, Kirti Relekar, Vijayalakshmi Prabhu
AIM: To evaluate visual outcome and endothelial cell density (ECD) after Descemet's Membrane Endothelial Keratoplasty (DMEK) in comparison with Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in the fellow eye for Fuchs endothelial dystrophy (FED). DESIGN: Single-centre, retrospective case series. METHODS: 30 eyes of 30 patients undergoing DMEK, who completed a 1-year follow-up, were compared with 30 fellow eyes which underwent DSAEK for bilateral FED...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26605365/the-evolution-of-corneal-and-refractive-surgery-with-the-femtosecond-laser
#18
REVIEW
Antonis Aristeidou, Elise V Taniguchi, Michael Tsatsos, Rodrigo Muller, Colm McAlinden, Roberto Pineda, Eleftherios I Paschalis
The use of femtosecond lasers has created an evolution in modern corneal and refractive surgery. With accuracy, safety, and repeatability, eye surgeons can utilize the femtosecond laser in almost all anterior refractive procedures; laser in situ keratomileusis (LASIK), small incision lenticule extraction (SMILE), penetrating keratoplasty (PKP), insertion of intracorneal ring segments, anterior and posterior lamellar keratoplasty (Deep anterior lamellar keratoplasty (DALK) and Descemet's stripping endothelial keratoplasty (DSEK)), insertion of corneal inlays and cataract surgery...
2015: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/26541104/anterior-corneal-surface-irregularity-after-descemet-stripping-endothelial-keratoplasty-for-bullous-keratopathy
#19
Leopoldo Spadea, Valentina Santamaria, Enzo Maria Vingolo, Carlo Cagini
PURPOSE: To evaluate irregularity of the anterior cornea before and after Descemet stripping endothelial keratoplasty (DSEK) for bullous keratopathy and its effect on visual acuity. METHODS: Corneal data were acquired using a topographic unit before and up to 12 months after DSEK. Anterior corneal elevation data were decomposed into a set of Zernike polynomials up to the 8th order within a 6.0-mm diameter region. Total higher-order aberrations (HOAs) and root mean square from the 3rd to 8th order were calculated...
May 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/26382899/graft-detachment-rate-in-dsek-dsaek-after-same-day-complete-air-removal
#20
Roy E Lehman, Laurel A Copeland, Eileen M Stock, Samuel F Fulcher
PURPOSE: We retrospectively analyzed the rate of graft detachment from 310 Descemet stripping endothelial keratoplasty (DSEK)/Descemet stripping automated endothelial keratoplasty (DSAEK) cases performed by a single surgeon over a 10-year period using same-day complete air removal. Secondary outcome measures including primary graft failure, late endothelial graft failure, rejection events, and steroid-induced ocular hypertension were also analyzed. METHODS: A retrospective chart review was performed on all patients receiving DSEK/DSAEK for any cause by the same surgeon at 2 separate institutions from January 2005 to December 2014...
November 2015: Cornea
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