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https://www.readbyqxmd.com/read/29339064/factors-associated-with-early-graft-detachment-in-primary-descemet-membrane-endothelial-keratoplasty
#1
Pia Leon, Mohit Parekh, Yoav Nahum, Michael Mimouni, Giuseppe Giannaccare, Laura Sapigni, Alessandro Ruzza, Massimo Busin
PURPOSE: To evaluate the risk factors for early graft detachment in Descemet Membrane Endothelial Keratoplasty (DMEK). DESIGN: Case-control Study. METHODS: ▪ PARTICIPANTS: 173 donor corneas and 173 eyes of the patients following DMEK or DMEK in combination with phacoemulsification and IOL implantation were included. INTERVENTION: Pre-stripped DMEK grafts were transplanted using pull-through technique. At the end of surgery, the anterior chamber was filled with air, which was removed 3 hours later only if pupillary block was suspected...
January 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29329121/technique-for-preparing-ultrathin-and-nanothin-descemet-stripping-automated-endothelial-keratoplasty-tissue
#2
Albert Y Cheung, Joshua H Hou, Peter Bedard, Veronique Grimes, Natalie Buckman, Medi Eslani, Edward J Holland
PURPOSE: To describe and report outcomes of our single-pass microkeratome technique for preparation of ultrathin (UT, ≤100 μm) and nanothin (NT, ≤50 μm) Descemet stripping automated endothelial keratoplasty (DSAEK) grafts. METHODS: To prepare NT-DSAEK grafts, a pachymetry nomogram specific to each technician and individual microkeratome head was developed based on accumulated precut and postcut pachymetry data from previous DSAEK grafts. Mean graft thickness as well as precut and postcut endothelial cell counts (ECCs) of NT-DSAEK, UT-DSAEK, and Descemet membrane endothelial keratoplasty (DMEK) grafts between July 2015 and July 2017 were calculated and compared statistically...
January 11, 2018: Cornea
https://www.readbyqxmd.com/read/29323218/scanning-electron-microscopy-assessment-of-the-descemet-membrane-interface-during-dmek-graft-preparation
#3
Javier Cabrerizo, Thomas Forshaw, Clara Rodriguez-Aierbe, Jesus Garrido-Fierro
We set out to determine microscopic characteristics of the Descemet membrane interface during Descemet membrane endothelial keratoplasty (DMEK) graft preparation. Ten corneas were partially prepared, preserving half of the Descemet membrane attached to the stroma to enable visualisation of the Descemet-stroma interface. This tissue was prepared for viewing with a scanning electron microscope. The Descemet-stroma interface was categorised into three regions: centre, mid-periphery and periphery. We classified adhesions in these regions as either minor thread-like adhesions or major bridge-like adhesions with stromal detachments...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29309360/partitioning-an-artificial-anterior-chamber-with-a-latex-diaphragm-to-simulate-anterior-and-posterior-segment-pressure-dynamics-the-dmek-practice-stage-where-surgeons-can-rehearse-the-dmek-dance
#4
Christopher S Sáles, Michael D Straiko, Ana Alzaga Fernandez, Kelly Odell, Philip K Dye, Khoa D Tran
PURPOSE: To present a novel apparatus for simulating the anterior and posterior segment pressure dynamics involved in executing Descemet membrane endothelial keratoplasty (DMEK) surgery when using a chamber-shallowing technique. METHODS: An artificial anterior chamber (AAC), 18-mm trephine, latex glove, two 3-mL syringes, and one donor cornea comprising an intact corneoscleral cap from which a DMEK tissue was peeled and punched are required for the model. After making the corneal incisions with the corneoscleral cap mounted on the AAC in the usual fashion, the corneoscleral cap is remounted onto the dried AAC over an 18-mm latex diaphragm...
February 2018: Cornea
https://www.readbyqxmd.com/read/29300261/scheimpflug-densitometry-after-dmek-versus-dsaek-two-year-outcomes
#5
Konstantinos Droutsas, Apostolos Lazaridis, Eleftherios Giallouros, Georgios Kymionis, Klio Chatzistefanou, Walter Sekundo
PURPOSE: To compare the course of Scheimpflug corneal densitometry (CD) after Descemet membrane endothelial keratoplasty (DMEK) versus Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Fifty-four DMEK and 25 DSAEK cases without previous corneal surgery, complicated intraoperative or postoperative course, or vision-limiting ocular comorbidities were included. Pseudophakic eyes of age-matched subjects were recruited as controls (n = 20). Scheimpflug CD of the optically relevant zones (0-2 and 2-6 mm), best-corrected visual acuity (BCVA), endothelial cell density, and central corneal thickness were evaluated preoperatively and at 3, 6, 12, and 24 months postoperatively...
January 3, 2018: Cornea
https://www.readbyqxmd.com/read/29298168/incidence-of-cystoid-macular-edema-after-descemet-membrane-endothelial-keratoplasty
#6
Viridiana Kocaba, Romain Mouchel, Jacques Fleury, Anne-Sophie Marty, Hélène Janin-Manificat, Delphine Maucort-Boulch, Carole Burillon
PURPOSE: The incidence of and risk factors for cystoid macular edema (CME) after Descemet membrane endothelial keratoplasty (DMEK) remain uncertain. This study examines the incidence of and risk factors for CME after DMEK. METHODS: This retrospective, single-center study included patients with no history of CME who had undergone DMEK. Patients were examined weekly for 1 month after surgery and at 3 and 6 months after surgery. Follow-up examinations included visual acuity (VA) assessment, pachymetry, anterior segment optical coherence tomography, biomicroscopy, intraocular pressure measurement, and fundoscopy...
January 2, 2018: Cornea
https://www.readbyqxmd.com/read/29260073/endothelial-keratoplasty-for-posterior-polymorphous-corneal-dystrophy-in-a-4-month-old-infant
#7
M Hermina Strungaru, Asim Ali, David Rootman, Kamiar Mireskandari
Purpose: To report a case of endothelial keratoplasties (EKs) performed in a 4 month old with a posterior polymorphous corneal dystrophy. Observations: A 4 month old infant underwent Descemet membrane endothelial keratoplasty (DMEK) for posterior polymorphous corneal dystrophy. The graft was found to be dislocated on day 5 post-operatively and an attempt to unfold the DMEK scroll and re-bubble was not successful. The patient was then treated successfully with bilateral Descemet stripping automated endothelial keratoplasty (DSAEK)...
September 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29242495/the-evolution-of-corneal-transplantation
#8
Tobias Röck, Johanna Landenberger, Matthias Bramkamp, Karl Ulrich Bartz-Schmidt, Daniel Röck
BACKGROUND The aim of this study was to investigate the evolution of surgical methods in and leading indications for corneal transplantation from 2005 to 2016. MATERIAL AND METHODS Data from the corneal graft waiting list and from all keratoplasties carried out between 2005 and 2016 at the University Eye Hospital Tübingen were retrospectively evaluated. RESULTS A total of 1259 keratoplasties were performed between 2005 and 2016 at the University Eye Hospital Tübingen. The most common surgical indications for corneal transplantation were Fuchs endothelial corneal dystrophy (45...
December 15, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29227339/comparison-of-sulfur-hexafluoride-sf6-and-air-tamponade-in-noniridectomized-descemet-membrane-endothelial-keratoplasty
#9
Adi Einan-Lifshitz, Nir Sorkin, Tanguy Boutin, Mahmood Showail, Armand Borovik, Farzad Jamshidi, Clara C Chan, David S Rootman
PURPOSE: To compare the efficacy and safety of 20% sulfur hexafluoride gas (SF6) and air tamponade in patients who underwent noniridectomized Descemet membrane endothelial keratoplasty (DMEK). METHODS: A retrospective chart review of patients who underwent DMEK with either air or SF6 tamponade: 41 eyes received air tamponade (group 1) and 41 received SF6 tamponade (group 2). Best spectacle-corrected visual acuity, endothelial cell density, and complications including graft detachment and elevated intraocular pressure were compared...
December 8, 2017: Cornea
https://www.readbyqxmd.com/read/29218212/heads-up-descemet-membrane-endothelial-keratoplasty-performed-using-a-3d-visualization-system
#10
Virgilio Galvis, Ruben D Berrospi, Juan D Arias, Alejandro Tello, Julio C Bernal
A 68-year-old female underwent Descemet membrane endothelial keratoplasty (DMEK) in her right eye using a 3D visualization system with the surgeon looking directly to a digital screen instead of through the eyepieces of the surgical microscope. The procedure was uneventful. Five weeks after the surgery the DMEK graft was in good position and totally adhered, the cornea clear and uncorrected distance visual acuity 20/50. This is the first reported case of DMEK using 3D augmented reality visualization system...
November 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29206654/descemet-membrane-endothelial-keratoplasty-and-glaucoma
#11
Marcus Ang, Chelvin C A Sng
PURPOSE OF REVIEW: The aim of this review is to describe the relationship between Descemet membrane endothelial keratoplasty (DMEK) and glaucoma. RECENT FINDINGS: Glaucoma after DMEK is a serious complication that may cause permanent visual loss, affect donor endothelial cells and graft survival. The mechanisms of raised intraocular pressure (IOP) after DMEK include reverse pupillary block in the early postoperative period, and steroid response in the late phase...
December 4, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29190797/topographic-characteristics-after-descemet-s-membrane-endothelial-keratoplasty-and-descemet-s-stripping-automated-endothelial-keratoplasty
#12
Takahiko Hayashi, Takefumi Yamaguchi, Kentaro Yuda, Naoko Kato, Yoshiyuki Satake, Jun Shimazaki
PURPOSE: To investigate the topographic characteristics of the posterior corneal surface after Descemet's endothelial membrane keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty (DSAEK) and their effects on postoperative visual acuity. METHODS: Nineteen eyes of 19 patients after DMEK, 23 eyes of 23 patients after DSAEK, and 18 eyes of 18 control subjects were retrospectively analyzed. Best spectacle-corrected visual acuity (BSCVA), aberration factors (higher-order aberrations [HOAs], spherical aberrations [SAs], and coma aberrations [Comas] at 6...
2017: PloS One
https://www.readbyqxmd.com/read/29148524/comparison-of-endothelial-cell-loss-and-complications-following-dmek-with-the-use-of-three-different-graft-injectors
#13
K Droutsas, A Lazaridis, G D Kymionis, K Chatzistefanou, M M Moschos, C Koutsandrea, W Sekundo
PurposeTo compare endothelial cell loss and complications following Descemet membrane endothelial keratoplasty (DMEK) with use of three commercially available injectors.MethodsFrom 179 consecutive DMEK procedures, 66 cases with uncomplicated graft preparation and completed 12-month follow-up were included in this retrospective study. According to the injector used, 3 groups were formed: group 1 (D.O.R.C. injector, n=16), group 2 (Geuder injector, n=24), and group 3 (Pasteur laboratory pipette, n= 26). Endothelial cell density (ECD) and endothelial cell loss were evaluated preoperatively and at 3, 6 and 12 months postoperatively; surgery-related complications were recorded...
November 17, 2017: Eye
https://www.readbyqxmd.com/read/29146479/visual-outcome-of-penetrating-keratoplasty-deep-anterior-lamellar-keratoplasty-and-descemet-membrane-endothelial-keratoplasty
#14
Clàudia Garrido, Genís Cardona, Josep L Güell, Jaume Pujol
PURPOSE: A single-center, cross-sectional study was designed to assess and compare objective and subjective quality of vision of patients intervened with penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) and Descemet membrane endothelial keratoplasty (DMEK). METHODS: Forty-six patients previously intervened with PK (22 eyes), DALK (7 eyes) and DMEK (17 eyes) were recruited. Visual evaluation included spherical and cylindrical refraction, distance corrected visual acuity (DCVA), photopic contrast sensitivity (CS), optical quality, measured with the HD Analyzer (objective scattering index [OSI], MTF cut-off and Strehl ratio), and ocular and corneal aberrometry, measured with the KR-1W Wavefront Analyzer...
November 13, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/29133296/comparison-of-preservation-and-transportation-protocols-for-preloaded-descemet-membrane-endothelial-keratoplasty
#15
Vito Romano, Mohit Parekh, Alessandro Ruzza, Colin E Willoughby, Stefano Ferrari, Diego Ponzin, Stephen B Kaye, Hannah J Levis
BACKGROUND/AIMS: Descemet membrane endothelial keratoplasty (DMEK) preparation is technically demanding and is a limiting factor for uptake of this kind of surgery. Supply methods that simplify the procedure for surgeons are key to increasing uptake. This study compares two different shipping protocols for DMEK. METHODS: An 8.5 mm DMEK graft was punched, marked and loaded for transportation in two different conditions: (A) endothelium trifolded inwards in organ culture conditions (n=7) and (B) endothelium rolled outwards in hypothermic conditions (n=7)...
November 13, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29120896/artificial-anterior-chamber-model-using-human-donor-corneas-for-dmek-surgical-training
#16
Rajesh Fogla, Richard Martinez
No abstract text is available yet for this article.
November 8, 2017: Cornea
https://www.readbyqxmd.com/read/29120722/recurrent-endothelial-rejection-after%C3%A2-dsaek-and-dmek-causing-corneal-perforation-in-a-patient-with-history-of%C3%A2-fuchs%C3%A2-endothelial-dystrophy-october-consultation-1
#17
Majid Moshirfar
No abstract text is available yet for this article.
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29040116/air-versus-sulfur-hexafluoride-gas-tamponade-in-descemet-membrane-endothelial-keratoplasty-a-fellow-eye-comparison
#18
Philipp V von Marchtaler, Julia M Weller, Friedrich E Kruse, Theofilos Tourtas
PURPOSE: To perform a fellow eye comparison of outcomes and complications when using air or sulfur hexafluoride (SF6) gas as a tamponade in Descemet membrane endothelial keratoplasty (DMEK). METHODS: One hundred thirty-six eyes of 68 consecutive patients who underwent uneventful DMEK in both eyes for Fuchs endothelial corneal dystrophy were included in this retrospective study. Inclusion criteria were air tamponade (80% of the anterior chamber volume) in the first eye and 20% SF6 gas tamponade (80% of the anterior chamber volume) in the second eye; and same donor tissue culture condition in both eyes...
October 13, 2017: Cornea
https://www.readbyqxmd.com/read/29034411/impact-of-corneal-donor-lens-status-on-two-year-course-and-outcome-of-descemet-membrane-endothelial-keratoplasty-dmek
#19
Friederike Schaub, Layla Pohl, Philip Enders, Werner Adler, Björn O Bachmann, Claus Cursiefen, Ludwig M Heindl
PURPOSE: Our purpose was to investigate the impact of lens status of corneal donors on the two-year course and clinical outcome of Descemet membrane endothelial keratoplasty (DMEK). METHODS: In 181 DMEK surgeries, 136 phakic and 45 pseudophakic donor corneas were grafted. In this retrospective audit we compared the lens status of corneal donors regarding the outcome measures best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), and endothelial cell density (ECD) at 1, 3, 6, 12, and 24 months, as well as intra- and postoperative complication rates and graft detachment rates requiring re-bubbling...
December 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28991851/quantitative-analysis-of-endothelial-cell-loss-in-preloaded-descemet-membrane-endothelial-keratoplasty-grafts
#20
Meraf A Wolle, David L DeMill, Lauren Johnson, Stephen I Lentz, Maria A Woodward, Shahzad I Mian
PURPOSE: Availability of preloaded Descemet membrane endothelial keratoplasty (pDMEK) tissue may increase acceptance of DMEK in surgical management of endothelial disease. The goal of this study was to determine the safety of pDMEK grafts for 24 hours before surgery by analyzing endothelial cell loss (ECL) using 2 image analysis software programs. METHODS: A total of 18 cadaveric corneas were prepared for DMEK using a standardized technique and loaded in a modified Jones tube injector...
November 2017: Cornea
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