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Surgery cognitive

Marie-Anne Durand, Julia Song, Renata West Yen, Karen Sepucha, Mary C Politi, Shubhada Dhage, Kari Rosenkranz, Julie Margenthaler, Anna N A Tosteson, Eloise Crayton, Sherrill Jackson, Ann Bradley, A James O'Malley, Robert J Volk, Elissa Ozanne, Sanja Percac-Lima, Jocelyn Acosta, Nageen Mir, Peter Scalia, Abigail Ward, Glyn Elwyn
Introduction. Breast cancer is the second most common malignancy in women. The Decision Quality Instrument (DQI) measures the extent to which patients are informed and involved in breast surgery decisions and receive treatment that aligns with their preferences. There are limited data on the performance of the DQI in women of lower socioeconomic status (SES). Our aims were to 1) examine (and if necessary adapt) the readability, usability, and acceptability of the DQI and 2) explore whether it captures factors important to breast cancer surgery decisions among women of lower SES (relevance)...
July 2018: MDM Policy & Practice
Anna-Karin Strand, Fredrik Nyqvist, Anne Ekdahl, Gun Wingren, Christina Eintrei
BACKGROUND: Long-term cognitive problems are common among elderly patients after surgery, and it has been suggested that inhalation anaesthetics play a role in the development of dementia. This study aims to investigate the hypothesis that patients with dementia have been more exposed to surgery and inhalational anaesthetics than individuals without dementia. METHODS: Using 457 cases from a dementia-registry and 420 dementia-free controls, we performed a retrospective case-control study...
December 3, 2018: Acta Anaesthesiologica Scandinavica
Jeremiah Maupin, Zackary Burrow, Cameron Shirazi, Santaram Vallurupalli
This is the case of a 66-year-old male with cervical myelopathy secondary to severe cervical stenosis manifesting as worsening dexterity and numbness in his right hand. The patient underwent C3-C6 laminoplasty with bilateral foraminotomies. During the procedure an incidental durotomy occurred which was patched intraoperatively with Duragen and Tisseel. At 1 month follow-up, the patient reported that he was doing well and skin sutures were removed. Two days later, the patient presented to the emergency department with postoperative wound dehiscence, cerebrospinal fluid (CSF) drainage, altered mental status and lethargy...
October 2018: Journal of Neurological Surgery Reports
Farzan Kheirkhah, GholamAbbas Roustaei, Elham Mohebbi Abivardi, Angela Hamidia, Sakineh Javadian Kutenai
Background: Cataract induced vision impairment can lead to loss of older people's independence and self-esteem and limit their daily activities. Moreover it has comorbid cognitive impairment and depression. Cataract surgery may be one way to attenuate these comorbidities. The aim of this study was to compare pre-operative and postoperative depressive symptoms and cognitive impairments of patients who underwent cataract surgery. Methods: This study was a before - after clinical trial...
2018: Caspian Journal of Internal Medicine
Sonja Brandner, Celine Aeberhard, Michael D Mueller, Annette Kuhn
OBJECTIVES: The need for pelvic floor surgery will increase with an aging population in the future. Aim of this prospective study was to evaluate the evolution of cognitive function in elderly women after urogynaecological surgery. MATERIAL AND METHODS: Between 2010 and 2014, 51 female patients 70 years and older who underwent urogynaecological surgery participated in this study. Geriatric and urogynaecological assessment were performed before and six weeks after surgery, including the Mini-COG test, the clock-drawing test, a depression scale, an activities of daily living questionnaire, and the German pelvic floor questionnaire...
2018: Ginekologia Polska
Simon T Schaefer, Stephan Koenigsperger, Cynthia Olotu, Thomas Saller
PURPOSE OF REVIEW: Neurocognitive dysfunction after surgery is highly relevant in the elderly. The multifactorial manner of this syndrome has made it hard to define an ideal biomarker to predict individual risk and assess diagnosis and severity of delirium [postoperative delirium (POD)] and subsequent postoperative cognitive decline (POCD). This review summarizes recent literature on blood biomarkers for POD/POCD. RECENT FINDINGS: Markers for delirium have been searched for in the cerebrospinal fluid to examine the pathologic cascade...
November 29, 2018: Current Opinion in Anaesthesiology
Roger D Dias, Heather M Conboy, Jennifer M Gabany, Lori A Clarke, Leon J Osterweil, David Arney, Julian M Goldman, Giuseppe Riccardi, George S Avrunin, Steven J Yule, Marco A Zenati
Procedural flow disruptions secondary to interruptions play a key role in error occurrence during complex medical procedures, mainly because they increase mental workload among team members, negatively impacting team performance and patient safety. Since certain types of interruptions are unavoidable, and consequently the need for multitasking is inherent to complex procedural care, this field can benefit from an intelligent system capable of identifying in which moment flow interference is appropriate without generating disruptions...
September 2018: OR 2.0 context-aware operating theaters, computer assisted robotic endoscopy, clinical image-based procedures, and skin image analysis: first International Workshop, OR 2.0 2018, 5th International Workshop, CARE 2018, 7th International Workshop, CLIP 201
Takahisa Ogawa, Takuya Aoki, Shinichi Shirasawa
BACKGROUND: Hip fracture constitutes a high-mortality injury in elderly patients. In addition, caregiver burden is also a relevant issue, as patients after hip fracture surgery lose ambulation and require support in the perioperative period and after discharge. Early surgery is recommended to improve mortality. However the positive effect of early surgery on the short-term postoperative ambulatory function is unknown. The objective of this study was to determine whether a shorter waiting time for hip fracture surgery improves short-term postoperative mobility in elderly patients...
November 28, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
Yuksel Altinel, Fahad Alkhalfan, Nidan Qiao, Marko Velimirovic
INTRODUCTION: Optimal surgical strategy for patients with tremor remains uncertain. We conducted a systematic review and meta-analysis evaluating randomized controlled trials of deep brain stimulation (DBS) and lesion surgery (LS) in treatment of tremor. METHODS: We searched PubMed, Embase and the Cochrane database to include randomized clinical trials with either lesion surgery, deep brain stimulation, or controls. The outcomes were the change in tremor score, quality of life, cognitive function, and neuropsychiatric function...
November 27, 2018: World Neurosurgery
Janni Strøm, Claus Vinther Nielsen, Lene Bastrup Jørgensen, Niels Trolle Andersen, Malene Laursen
BACKGROUND: Approximately one-third of patients undergoing spine surgery have symptoms of anxiety and depression that correlate with pain, disability, and lower health-related quality of life. The use of web-based informative strategies before surgery and principles from cognitive behavioral therapy, have been applied in other patient groups, facilitating mobility and encouraging beneficial coping behavior. PURPOSE: To examine the effect of a web-based Spine Platform featuring Interaction and Information by Animation (w-SPIINA) on symptoms of anxiety and depression, pain, disability, and health-related quality of life...
November 27, 2018: Spine Journal: Official Journal of the North American Spine Society
Michel E van Genderen, J H Vlake
Innovative technologies, such as virtual reality (VR), augmented reality (AR) and mixed reality (MR) are no longer only interesting for a niche of gamers but are increasingly being applied within healthcare. Possible applications for VR in care vary from exposure therapy for PTSD and anxiety disorders to aiding in cognitive and physical rehabilitation. VR has also acquired an important role in medical education. AR/MR are used predominantly within surgery, for instance for perioperative projection of patient information, holographic images and scans...
November 26, 2018: Nederlands Tijdschrift Voor Geneeskunde
Saad Y Salim, Marjan Govaerts, Jonathan White
OBJECTIVE: The aim of this study was to explore how trust was constructed between surgeons and residents in the operating room. BACKGROUND: Entrustment is increasingly being used as a key element to assess trainees' competence in the clinical workplace. However, the cognitive process involved in the formulation of surgical trust remains poorly understood. METHODS: In semistructured interviews, 9 general surgeons discussed their experiences in making entrustment decisions during laparoscopic cholecystectomy...
November 29, 2018: Annals of Surgery
Xu-Dong Yang, Li-Kuan Wang, Hai-Yin Wu, Liang Jiao
BACKGROUND: Surgery-induced neuroinflammation plays an important role in postoperative cognitive dysfunction (POCD). Gut microbiota is a key regulator of neurological inflammation. Nurturing with prebiotics is an effective microbiota manipulation that can regulate host immunity and cognition. The aim of the present study was to test whether administration of the prebiotic Bimuno® (galactooligosaccharide (B-GOS) mixture) could ameliorate POCD and attenuate surgery-induced neuroinflammation through the microbiota-brain-axis...
November 30, 2018: BMC Anesthesiology
(no author information available yet)
OBJECTIVEDifferent CSF diversion procedures (ventriculoperitoneal, ventriculoatrial, and lumboperitoneal shunting) have been utilized for the treatment of idiopathic normal pressure hydrocephalus. More recently, endoscopic third ventriculostomy has been suggested as a reasonable alternative in some studies. The purpose of this study was to perform a systematic review and meta-analysis to assess overall rates of favorable outcomes and adverse events for each of these treatments. An additional objective was to determine the outcomes and complication rates in relation to the type of valve utilized (fixed vs programmable)...
November 1, 2018: Journal of Neurosurgery
Kathryn M Emmer, William H Walker, Ning Zhang, A Courtney DeVries
Understanding why breast cancer survivors are at an increased risk for cognitive and affective disorders is essential for developing targeted treatment plans and improving quality of life. Microglia priming results in chronic neuroinflammation and can contribute to neuronal degeneration and dysfunction, thereby offering a potential mechanism for altered brain function that persists after tumor removal. This study examined whether mammary tumors alter microglia and augment the inflammatory profile and behavior of mice...
November 26, 2018: Brain Research
N U Farrukh Hameed, Bin Wu, Fangyuan Gong, Jie Zhang, Hong Chen, Jinsong Wu
Two techniques, the translongitudinal cerebral fissure and transfrontal cortical approach, can be employed to resect posterior cingulate gyrus tumors. We demonstrate the transcortical technique comprising of multimodal imaging guidance and awake brain mapping which enabled maximum safe resection of dominant cingulate gyrus glioma. The patient, a 49-yr-old female, came to clinic after experiencing headache for a month. Initial magnetic resonance imaging (MRI) scans revealed a nonenhancing lesion of the left posterior cingulate gyrus...
November 28, 2018: Operative Neurosurgery (Hagerstown, Md.)
Cecilia Malmsten, Pär Hellberg, Karin Bergmark, Pernilla Dahm-Kähler
PURPOSE: Our aim was to evaluate fertility-sparing surgery of early stage cervical cancer after the introduction of vaginal trachelectomy (VT) and pelvic lymph node dissection (PLND). The objectives were to assess surgical, long-term oncological, fertility, and obstetric outcomes together with self-assessed quality of life (QoL). METHODS: All women ≤ 40 years diagnosed with early stage cervical cancers IA1-IB1 and ≤ 2 cm treated by VT and PLND between 2000 and 2014 were included...
November 28, 2018: Archives of Gynecology and Obstetrics
Mandy Malick, Kim Gilbert, Jonathan Brouillette, Roger Godbout, Guy Rousseau
Myocardial infarction (MI) in animal models induces cognitive deficits as well as the activation of caspase in the limbic system; both can be blocked by 2 weeks of treatment following MI using tricyclic antidepressants or selective serotonin uptake blockers. Here we used three different treatment schedules to test the short- and long-term effects of the combined serotonin-norepinephrine reuptake inhibitor desvenlafaxine on post-MI-associated cognitive deficits and caspase activation. MI was induced in 39 young adult rats, and 39 rats served as sham-operated controls...
November 26, 2018: International Journal of Molecular Sciences
Huixin Chen, Xiang Wu, Xinmei Gu, Yiying Zhou, Luying Ye, Ke Zhang, Hanbo Pan, Jialing Wang, Hua Wei, Binbin Zhu, C Benjamin Naman, Shinghung Mak, Paul R Carlier, Wei Cui, Yifan Han
Post-operative cognitive dysfunction (POCD) could cause short-term or long-term cognitive disruption lasting weeks or months after anesthesia and surgery in elderly. However, no effective treatment of POCD is currently available. Previous studies indicated that the enhancement of brain-derived neurotrophic factor (BDNF) expression, and the elevation the cholinergic system, might be effective to prevent POCD. In this study, we have discovered that tacrine(10)-hupyridone (A10E), a novel acetylcholinesterase (AChE) inhibitor derived from tacrine and huperzine A, could prevent surgery-induced short-term and long-term impairments of recognition and spatial cognition, as evidenced by the novel object recognition test and Morris water maze (MWM) tests, in aged mice...
2018: Frontiers in Cellular Neuroscience
Ara Ko, Se Hee Kim, Se Hoon Kim, Eun Kyung Park, Kyu-Won Shim, Hoon-Chul Kang, Dong-Seok Kim, Heung Dong Kim, Joon Soo Lee
OBJECTIVE: Low-grade epilepsy-associated tumors (LEATs) are associated with childhood seizures that are typically drug-resistant, necessitating surgical interventions. In this study, we aimed to investigate the efficacy of surgical intervention in children with LEATs and to identify factors associated with seizure and cognitive outcomes. METHODS: We reviewed 58 children less than 18 years of age who underwent epilepsy surgery due to histopathologically confirmed LEATs and had a minimum postoperative follow-up duration of 24 months...
October 24, 2018: Pediatric Neurology
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