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Salil V Deo, Sajjad Raza, Salah E Altarabsheh, Vaishali S Deo, Yakov E Elgudin, Shayan Marsia, Stephen Mitchell, Carolyn Chang, Ankur Kalra, Sahil Khera, Dhaval Kolte, Marco Costa, Daniel Simon, Alan H Markowitz, Soon J Park, Joseph F Sabik
BACKGROUND: Re-admission is an important source of patient dissatisfaction and increased hospital costs. A simple calculator to determine the probability of re-admission may help guide patient dismissal planning. METHODS: Using the national readmissions database (NRD), we identified admissions for isolated primary coronary artery bypass (CABG) and stratified them according to 30-day readmission. Including pre, intra and postoperative variables, we prepared a logistic regression model to determine the probability for re-admission...
November 29, 2018: Heart, Lung & Circulation
David Shau, Neeta Shenvi, Kirk Easley, Melissa Smith, Thomas Bradbury, George Guild
BACKGROUND: Medicaid payer status has been shown to affect risk-adjusted outcomes and resource utilization across multiple medical specialties. The purpose of this study was to examine resource utilization via readmission rates, length of stay, and total cost specific to Medicaid payer status following primary total hip arthroplasty. METHODS: The Nationwide Readmissions Database (NRD) was utilized to identify patients who underwent total hip arthroplasty in 2013 as well as corresponding "Medicaid" or "non-Medicaid" payer status...
December 5, 2018: Journal of Bone and Joint Surgery. American Volume
Dan-Dan Zhang, Gan Lu, Xuan-Feng Zhu, Ling-Ling Zhang, Jia Gao, Li-Cheng Shi, Jian-Hua Gu, Jian-Nan Liu
Background: Neural respiratory drive (NRD) using diaphragm electromyography through an invasive transesophageal multi-electrode catheter can be used as a feasible clinical physiological parameter in patients with chronic obstructive pulmonary disease (COPD) to provide useful information on the treatment response. However, it remains unknown whether the surface diaphragm electromyogram (EMGdi) could be used to identify the deterioration of clinical symptoms and to predict the necessity of hospitalization in acute exacerbation of COPD (AECOPD) patients...
December 5, 2018: Chinese Medical Journal
Junya Mizoi, Natsumi Kanazawa, Satoshi Kidokoro, Fuminori Takahashi, Feng Qin, Kyoko Morimoto, Kazuo Shinozaki, Kazuko Yamaguchi-Shinozaki
Plants have evolved complex systems to rapidly respond to severe stress conditions, such as heat, cold, and dehydration. DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 2A (DREB2A) is a key transcriptional activator that induces many heat- and drought-responsive genes, increases tolerance to both heat and drought stress, and suppresses plant growth in Arabidopsis thaliana DREB2A expression is induced by stress, but stabilization of the DREB2A protein in response to stress is essential for activating the expression of downstream stress-inducible genes...
November 28, 2018: Journal of Biological Chemistry
Stephanie Doupnik, Jonathan Rodean, Bonnie T Zima, Tumaini R Coker, Diana Worsley, Kris P Rehm, James C Gay, Matt Hall, Steve Marcus
OBJECTIVE: To inform resource allocation toward a continuum of care for youth at risk of suicide, we examined unplanned 30-day readmissions after pediatric hospitalization for either suicide ideation (SI) or suicide attempt (SA). METHODS: We conducted a retrospective cohort study of a nationally representative sample of 133,516 hospitalizations for SI or SA among 6- to 17-year-olds to determine prevalence, risk factors, and characteristics of 30-day readmissions using the 2013 and 2014 Nationwide Readmissions Dataset (NRD)...
November 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Jonas Boström, Dean G Brown, Robert J Young, György M Keserü
This corrects the article DOI: 10.1038/nrd.2018.116.
November 28, 2018: Nature Reviews. Drug Discovery
Zain H Rizvi, Rocco Ferrandino, Quang Luu, Jeffrey D Suh, Marilene B Wang
BACKGROUND: Transsphenoidal pituitary surgery has evolved into a safe procedure with shorter hospitalizations, yet unplanned readmissions remain a quality measure for which there is a paucity of data. We sought to examine rates, timing, etiologic factors, and costs surrounding readmission after transsphenoidal pituitary surgery. METHODS: The Nationwide Readmissions Database (NRD) was queried for patients who underwent transsphenoidal pituitary between January 2013 and November 2013...
November 23, 2018: International Forum of Allergy & Rhinology
Spyridon N Karras, Theocharis Koufakis, Andrea Petróczi, Dirk Folkerts, Maria Kypraiou, Hilda Mulrooney, Declan P Naughton, Angeliki Persynaki, Pantelis Zebekakis, Dimitrios Skoutas, Kalliopi Kotsa
OBJECTIVES: Christian Orthodox fasting (COF), a periodical vegetarian subset of the Mediterranean diet, has been proven to exert beneficial effects on human health. Athonian fasting is a pescetarian COF variation, where red meat is strictly restricted throughout the year. Previous studies have examined the COF nutritional synthesis and health effects in general population fasters (GF) and Athonian monks (AM), separately. The aim of this study is to comparatively evaluate the characteristics and effects of this nutritional advocacy between the two populations...
July 24, 2018: Nutrition
Rushikesh Shah, Emad Qayed
OBJECTIVES: Gastrointestinal (GI) bleeding is a major comorbidity in patients with left ventricular assist devices (LVADs). The study aim was to estimate the rate of hospital readmissions for GI bleeding in patients with LVADs using a nationally representative database. Additionally, we evaluated the etiologies, costs, endoscopy utilization, mortality, and predictors of GI bleeding readmissions in these patients. METHODS: We analyzed data from the National Readmissions Database (NRD) from 2010 through 2014...
November 2018: Southern Medical Journal
Luke K Kim, Ilhwan Yeo, Jim W Cheung, Rajesh V Swaminathan, S Chiu Wong, Konstantinos Charitakis, Oluwayemisi Adejumo, John Chae, Robert M Minutello, Geoffrey Bergman, Harsimran Singh, Dmitriy N Feldman
Background Readmission after ST-segment-elevation myocardial infarction ( STEMI ) poses an enormous economic burden to the US healthcare system. Efforts to prevent readmissions should be based on understanding the timing and causes of these readmissions. This study aimed to investigate contemporary causes, timing, and cost of 30-day readmissions after STEMI . Methods and Results All STEMI hospitalizations were selected in the Nationwide Readmissions Database ( NRD ) from 2010 to 2014. The 30-day readmission rate as well as the primary cause and cost of readmission were examined...
September 18, 2018: Journal of the American Heart Association
Srikanth Yandrapalli, Wilbert S Aronow, William H Frishman
Background: Influenza epidemics are a major health care concern in the US. Influenza related complications can increase in-hospital complications, and readmissions following a hospitalization for influenza. We sought to determine the 30-day readmission rate, etiologies, outcomes, and healthcare burden of 30-day readmissions in adults hospitalized for influenza. Methods: The 2014 US National Readmissions Database (NRD) was retrospectively analyzed to identify patients ≥18 years of age hospitalized for influenza and discharged between January and November 2014...
August 2018: Annals of Translational Medicine
Jun Tang, Laura Pearce, Jill O'Donnell-Tormey, Vanessa M Hubbard-Lucey
This corrects the article DOI: 10.1038/nrd.2018.167.
October 26, 2018: Nature Reviews. Drug Discovery
Raymond A Jean, Alex S Chiu, Jessica R Hoag, Justin D Blasberg, Daniel J Boffa, Frank C Detterbeck, Anthony W Kim
BACKGROUND: Readmissions after pulmonary lobectomy for lung cancer are important markers of healthcare quality for surgeons and hospitals. The implications on resources and quality are magnified when examining patients who require multiple readmissions within the perioperative period. METHODS: The Nationwide Readmission Database (NRD) between 2013 and 2014 was investigated for patients with a primary diagnosis of lung cancer who underwent pulmonary lobectomy. Using adjusted hierarchical regression models, demographic and clinical factors during the index hospitalization were investigated for associations with single and multiple readmissions during the 90-day postoperative period...
October 15, 2018: Annals of Thoracic Surgery
Delphine Charvin, Rossella Medori, Robert A Hauser, Olivier Rascol
This corrects the article DOI: 10.1038/nrd.2018.136.
October 12, 2018: Nature Reviews. Drug Discovery
Saman Setareh-Shenas, Felix Thomas, Robert M Cole, Alejandro Lemor, Eyal Herzog, Francisco Arabia, Jaime Moriguchi
Ventricular assist device (VAD) implantation has improved quality of life and short-term survival for advanced heart failure patients. There are limited data from single-center studies addressing the characteristics and etiologies of 30 day readmissions after VAD implant. We used the Nationwide Readmissions Database (NRD) 2014 to identify insertion of implantable heart assist system during index admission. Primary and secondary outcomes were 30 day readmissions and leading etiologies, respectively. We analyzed 1,481 patients who received VAD during the primary admission of whom 1,315 patients survived to hospital discharge (mortality rate 11...
October 3, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Jonathan J Cui, Raj J Gala, Nathaniel T Ondeck, Ryan P McLynn, Patawut Bovonratwet, Blake Shultz, Jonathan N Grauer
BACKGROUND CONTEXT: Posterior lumbar fusion (PLF) is a commonly performed procedure. The evolution of bundled payment plans is beginning to require physicians to more closely consider patient outcomes up to 90 days after an operation. Current quality metrics and other databases often consider only 30 postoperative days. The relatively new Healthcare Cost and Utilization Project Nationwide Readmissions Database (HCUP-NRD) tracks patient-linked hospital admissions data for up to one calendar year...
September 13, 2018: Spine Journal: Official Journal of the North American Spine Society
Khalid Mumtaz, Abdulfatah Issak, Kyle Porter, Sean Kelly, James Hanje, Anthony J Michaels, Lanla F Conteh, Ashraf El-Hinnawi, Sylvester M Black, Marwan S Abougergi
INTRODUCTION: The early readmission in patients with decompensated liver cirrhosis leads to enormous burden on healthcare utilization. METHODS: Retrospective cohort study using the 2013 and 2014 Nationwide Readmission Database (NRD) was conducted. Patients with diagnoses of cirrhosis and at least one feature of decompensation were included. The primary outcome was to develop a validated risk model for early readmission. Secondary outcomes were to study 30-day all cause-readmission rate and most common reasons for readmission...
September 15, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
Turner Osler, Dekang Yuan, Jeremy Holden, Zihao Huang, Alan Cook, Laurent G Glance, Jeffrey S Buzas, David W Hosmer
INTRODUCTION: Readmission following hospital discharge is both common and costly. The Hospital Readmission Reduction Program (HRRP) financially penalizes hospitals for readmission following admission for some conditions, but this approach may not be appropriate for all conditions. We wished to determine if hospitals differed in their adjusted readmission rates following an index hospital admission for traumatic injury. PATIENTS AND METHODS: We extracted from the AHRQ National Readmission Dataset (NRD) all non-elderly adult patients hospitalized following traumatic injury in 2014...
August 27, 2018: Injury
Vincenzo Di Marzo
This corrects the article DOI: 10.1038/nrd.2018.115.
August 30, 2018: Nature Reviews. Drug Discovery
Purav Shah, Shilpkumar Arora, Varun Kumar, Surina Sharma, Harshil Shah, Byomesh Tripathi, Purnima Sharma, Ravina Sharma, Sejal Savani, Muhammad Raheel Qureshi, Ibrahim Faruqi
BACKGROUND: Pulmonary embolism (PE) is associated with significant morbidity and mortality in hospitalized patients. Real time data on 90-day mortality, bleeding, and readmission is sparse. METHODS: The study cohort was derived from the National Readmission Data (NRD) 2013 to 2014. PE was identified using International Classification of Diseases, ninth Revision (ICD-9-CM) code 415.11/3/9 in the primary diagnosis field. Any admission within 90 days of primary admission was considered a 90-day readmission...
September 2018: Clinical Cardiology
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