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Gülay Gök, Tufan Çınar, Nurten Sayar
INTRODUCTION: Rheumatic mitral stenosis (MS) is an important health issue in developing countries. Assessment of the correct mitral valve area (MVA) is essential for the timing of intervention. Most of the parameters for the assessment of rheumatic MS are derived from Two-dimensional (2D) echocardiography. Three-dimensional (3D) echocardiography is commonly used in our daily practice at the present time. The aim of this study was to assess the value of 3D echocardiography mitral valve vena contracta area (VCA) in predicting the severity of Rheumatic MS by comparing 3D planimetry...
December 11, 2018: Echocardiography
Kim Hébert-Losier, Ngieng Siew Yin, C Martyn Beaven, Chris Chow Li Tee, Jim Richards
Kinesiology-type tape (KTT) has become popular in sports for injury prevention, rehabilitation, and performance enhancement. Many cyclists use patella KTT; however, its benefits remain unclear, especially in uninjured elite cyclists. We used an integrated approach to investigate acute physiological, kinematic, and electromyographic responses to patella KTT in twelve national-level male cyclists. Cyclists completed four, 4-minute submaximal efforts on an ergometer at 100 and 200 W with and without patella KTT...
November 19, 2018: Journal of Electromyography and Kinesiology
Nikoloz Koshkelashvili, Priya Kohli, Jason Linefsky
CLINICAL INTRODUCTION: A 57-year-old man from the USA with a history of atrial fibrillation and hypertension was evaluated for progressive dyspnoea and decreased energy. The patient denied a history of congestive heart failure, systemic symptoms or myocardial infarction. He was found to have a 3/6 holosystolic murmur radiating to the axilla. Transthoracic echocardiography (TTE) reported a reduced ejection fraction of 40%, mitral valve regurgitation and absence of interatrial shunts. The remaining cardiac valves were without abnormality...
November 22, 2018: Heart: Official Journal of the British Cardiac Society
Valentina Volpato, Roberto M Lang, Megan Yamat, Federico Veronesi, Lynn Weinert, Gloria Tamborini, Manuela Muratori, Laura Fusini, Mauro Pepi, Davide Genovese, Victor Mor-Avi, Karima Addetia
BACKGROUND: Evaluation of the tricuspid annulus is crucial for the decision making at the time of left heart surgery. Current recommendations for tricuspid valve repair are based on two-dimensional (2D) transthoracic echocardiography (TTE), despite the known underestimation compared with three-dimensional (3D) echocardiography. However, little is known about the differences in 3D tricuspid annular (TA) sizing using TTE versus transesophageal echocardiography (TEE). The aims of this study were to (1) compare 2D and 3D TA measurements performed with both TTE and TEE and (2) compare two 3D methods for TA measurements: multiplanar reconstruction (MPR) and dedicated software (DS) designed to take into account TA nonplanarity...
November 17, 2018: Journal of the American Society of Echocardiography
Stefaan Bouchez, G Burkhard Mackensen, Eckhard Mauermann, Linda McCleish, Frederick Cobey, Madhav Swaminathan, Patrick Wouters
OBJECTIVES: In this measurement validation study, the authors evaluated agreement between 2-dimensional (2D) and three-dimensional (3D) transesophageal echocardiography (TEE), measuring anterior mitral valve leaflet length by both novice and experienced echocardiographers. DESIGN: This was a retrospective, observational study. SETTING: Single university hospital. PARTICIPANTS: Analyses on datasets from 44 patients. INTERVENTIONS: None...
July 7, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Lars Fokdal, Kari Tanderup, Richard Pötter, Alina Sturdza, Kathrin Kirchheiner, Cyrus Chargari, Ina Maria Jürgenliemk-Schulz, Barbara Segedin, Li-Tee Tan, Peter Hoskin, Umesh Mahantshetty, Kjersti Bruheim, Bhavana Rai, Christian Kirisits, Jacob Christian Lindegaard
BACKGROUND: and purpose: Ureteral stricture is a rare but severe side effect, after radiotherapy for locally advanced cervical cancer (LACC). This report describes the incidence and predictive factors for ureteral stricture in a large patient cohort treated with 3D image guided adaptive brachytherapy (IGABT) and radiochemotherapy within the XXXXXXX studies. MATERIAL AND METHODS: A total of 1860 patients were included. Treatment consisted of external beam radiotherapy (45-50 Gy in 25-30 fx), concomitant Cisplatin and IGABT...
November 9, 2018: International Journal of Radiation Oncology, Biology, Physics
Flavia Ballocca, Lukas M Meier, Karim Ladha, Joshua Qua Hiansen, Eric M Horlick, Massimiliano Meineri
OBJECTIVE: The use of 3-dimensional (3D) transesophageal echocardiography (TEE) in perioperative evaluation of the mitral valve (MV) is increasing progressively, including the use of 3D MV models for quantitative analysis. However, the use of 3D MV models in clinical practice still is limited by the need for specific training and the long time required for analysis. A new stereoscopic visualization tool (EchoPixel True 3D) allows virtual examination of anatomic structures in the clinical setting, but its accuracy and feasibility for intraoperative use is unknown...
August 11, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Thilo Noack, Philipp Kiefer, Linda Mallon, Philipp Lurz, Carmine Bevilacqua, Joergen Banusch, Fabian Emrich, David M Holzhey, Mani Vannan, Holger Thiele, Friedrich-Wilhelm Mohr, Michael Andrew Borger, Joerg Ender, Joerg Seeburger
BACKGROUND: The aim of this study was to quantify the acute dynamic changes of mitral valve (MV) geometry throughout the cardiac cycle-during percutaneous MV repair with the MitraClip system by 3-dimensional transesophageal echocardiography (3D TEE). METHODS: The MV was imaged throughout the cardiac cycle (CC) before and after the MitraClip procedure using 3D TEE in 28 patients (mean age, 77 ± 8 years) with functional mitral regurgitation (FMR). Dynamic changes in the MV annulus geometry and anatomical MV orifice area (AMVOA) were quantified using a novel semi-automated software...
October 5, 2018: Journal of Echocardiography
Pedro Morais, Sandro Queiros, Pieter De Meester, Werner Budts, Joao L Vilaca, Joao Manuel R S Tavares, Jan D'hooge
Left atrial appendage (LAA) has been generally described as "our most lethal attachment", being considered the major source of thromboembolism in patients with non-valvular atrial fibrillation. Currently, LAA occlusion can be offered as a treatment for these patients, obstructing the LAA through a percutaneously delivered device. Nevertheless, correct device sizing is not straightforward, requiring the manual analysis of peri-procedural images. This approach is sub-optimal, time demanding and highly variable between experts, which can result in lengthy procedures and excess manipulations...
September 28, 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Noman Ali, Smriti Saraf, Dominik Schlosshan, Michael Cunnington, Christopher J Malkin, Daniel J Blackman
Trans-catheter aortic valve implantation (TAVI) has become an established treatment for inoperable and high-surgical risk patients with severe, symptomatic aortic stenosis (AS). Post-procedural acute kidney injury (AKI) is a frequent complication following TAVI and is associated with increased mortality. Patients with pre-existing chronic renal impairment are at particularly high risk. The etiology of post-TAVI AKI is multi-factorial, but the principal procedural issues are contrast-induced nephropathy, and renal hypoperfusion secondary to intra-procedural hypotension...
October 2018: Journal of Cardiology Cases
Fabien Praz, Omar K Khalique, Leon G Dos Reis Macedo, Todd C Pulerwitz, Jennifer Jantz, Isaac Y Wu, Alex Kantor, Amisha Patel, Torsten Vahl, Vinayak Bapat, Isaac George, Tamim Nazif, Susheel K Kodali, Martin B Leon, Rebecca T Hahn
BACKGROUND: Tricuspid valve imaging is frequently challenging and requires the use of multiple modalities. Knowledge of limitations and methodologic discrepancies among different imaging techniques is crucial for planning transcatheter valve interventions. METHODS: Thirty-eight patients with severe symptomatic tricuspid regurgitation were included in this retrospective analysis. Tricuspid annulus (TA) measurements were made during mid-diastole using three-dimensional (3D) transthoracic echocardiographic direct planimetry (TTE_direct) and transesophageal echocardiographic direct planimetry (TEE_direct)...
September 27, 2018: Journal of the American Society of Echocardiography
Y Song, S-C Qin, X Fu, Z-M Jiang, K Chen, X-L Wang, R-F Zhang, Y Liuang, R-F Zhang, Y Liu
OBJECTIVE: To investigate the efficacy of transesophageal echocardiography (TEE) in the treatment of nonvalvular atrial fibrillation with left atrial appendage (LAA) occlusion. PATIENTS AND METHODS: Forty-nine patients with nonvalvular atrial fibrillation were selected from January 2015 to December 2015 to serve as control group, and 49 patients with nonvalvular atrial fibrillation were selected from January 2016 to December 2016 to serve as observation group. Patients in both groups were treated with LAA occlusion...
August 2018: European Review for Medical and Pharmacological Sciences
Tao Cong, Jinping Gu, Alex Pui-Wai Lee, Zhijuan Shang, Yinghui Sun, Qiaobing Sun, Hong Wei, Na Chen, Siyao Sun, Tingting Fu
BACKGROUND: Atrial fibrillation (AF) can result in atrial functional mitral regurgitation (MR), but the mechanism remains controversial. Few data about the relationship between the 3-dimensional morphology of the MV and the degree of MR in AF exist. METHODS: Real-time 3-dimensional transesophageal echocardiography (3D-TEE) of the MV was acquired in 168 patients with AF (57.7% persistent AF), including 25 (14.9%) patients with moderate to severe MR (the MR+ group) and 25 patients without AF as controls...
August 21, 2018: Cardiovascular Ultrasound
Thilo Noack, Kathleen Wittgen, Philipp Kiefer, Fabian Emrich, Matthias Raschpichler, Sarah Eibel, David Holzhey, Martin Misfeld, Friedrich-Wilhelm Mohr, Michael Borger, Joerg Ender, Joerg Seeburger
BACKGROUND:  The aim of this study was to quantify acute mitral valve (MV) geometry dynamic changes throughout the cardiac cycle using three-dimensional transesophageal echocardiography (3D TEE) in patients undergoing surgical MV repair (MVR) with ring annuloplasty and optional neochord implantation. METHODS:  Twenty-nine patients (63 ± 10 years) with severe primary mitral regurgitation underwent surgical MVR using ring annuloplasty with or without neochord implantation...
August 16, 2018: Thoracic and Cardiovascular Surgeon
Verya Daeichin, Deep Bera, Shreyas Raghunathan, Maysam Shabani Motlagh, Zhao Chen, Chao Chen, Emile Noothout, Hendrik J Vos, Michiel Pertijs, Johan G Bosch, Nico de Jong, Martin Verweij
This paper presents the design, fabrication and characterization of a miniature PZT-on-CMOS matrix transducer for real-time pediatric 3-dimensional (3D) transesophageal echocardiography (TEE). This 3D TEE probe consists of a 32 × 32 array of PZT elements integrated on top of an Application Specific Integrated Circuit (ASIC). We propose a partitioned transmit/receive array architecture wherein the 8 × 8 transmitter elements, located at the centre of the array, are directly wired out and the remaining receive elements are grouped into 96 sub-arrays of 3 × 3 elements...
October 2018: Ultrasound in Medicine & Biology
Inês Delgado, Ana Fonte Boa, Ana Filipa Carvalho, Bruno Melica, Pedro Braga, Vasco Gama Ribeiro
The percutaneous MitraClip system is a catheter-based device designed to perform edge-to-edge mitral valve (MV) leaflet repair at the site of regurgitation. MitraClip implantation is an alternative procedure in patients at high surgical risk with symptomatic severe mitral regurgitation (MR) who are not candidates for MV repair/replacement due to their degree of comorbidity and associated high mortality risk. The procedure is guided by 3-dimensional (3D) transesophageal echocardiography (TEE) and fluoroscopy...
August 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Sonia A El-Saiedi, Hala M Agha, Mohamed F Shaltoot, Hayat H Nassar, Amal M El Sisi, Wael A Attia, Yasser M Sedky
Objective: Real-time three-dimensional echocardiography, using both reconstruction methods and RT3D, has been used as an extra helping tool in several forms of congenital heart diseases. Our aim was to understand the relation of the ASD device to all surrounding structures by 3-dimensional echocardiography (3D). Methods: This prospective study included 37 patients diagnosed as ASD secundum by transthoracic (TTE) and transesophageal echocardiography (TEE) referred for transcatheter closure from October 2013 to July 2016...
July 2018: Journal of the Saudi Heart Association
Tasneem Z Naqvi
Transesophageal echocardiography (TEE) plays a significant role during transcatheter aortic valve implantation (TAVR). 2DTEE allows assessment of anatomy of the aortic valve, aortic root, left ventricular (LV) outflow tract, severity of the aortic valve stenosis (AS), and the presence and severity of other valve stenosis and regurgitation. Left and right ventricular size and global function as well as cardiac hemodynamics pre and post TAVR and LV regional wall motion can be assessed. Three-dimensional (3D) imaging adds significantly via accurate measurement of aortic annulus that helps select the appropriate valve size...
July 2018: Echocardiography
Begum Uygur, Omer Celik, Fethi Emre Ustabasioglu, Okan Akinci, Mehmet Erturk
AIM: Rheumatic heart disease is a common cause of valvular disease, especially in developing countries. Echocardiography is the gold standard investigation modality for cardiac valves. In rheumatic mitral stenosis (MS), three-dimensional transesophageal echocardiography (3D TEE) provides better alignment of the image plane at the mitral tips and more accurate and reproducible planimetric measurement of mitral valve area (MVA). Cardiac magnetic resonance (CMR) is a new method that provides evaluation of cardiac anatomy and function noninvasively...
October 2018: Echocardiography
Charlotte E Johnson, Elaine A Dunlop, Sara Seifan, Henry D McCann, Trevor Hay, Geraint J Parfitt, Ashley T Jones, Peter J Giles, Ming H Shen, Julian R Sampson, Rachel J Errington, D Mark Davies, Andrew R Tee
Cancer cells lose homeostatic flexibility because of mutations and dysregulated signaling pathways involved in maintaining homeostasis. Tuberous Sclerosis Complex 1 (TSC1) and TSC2 play a fundamental role in cell homeostasis, where signal transduction through TSC1/TSC2 is often compromised in cancer, leading to aberrant activation of mechanistic target of rapamycin complex 1 (mTORC1). mTORC1 hyperactivation increases the basal level of endoplasmic reticulum (ER) stress via an accumulation of unfolded protein, due to heightened de novo protein translation and repression of autophagy...
November 2018: Oncogene
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