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Neonates intensive care paediatrics

Daynia Elizabeth Ballot, Tanusha Ramdin, Debbie Ann White, Jeffrey Lipman
OBJECTIVE: Paediatric intensive care resources are limited in sub-Saharan Africa. The mortality rate in a combined Paediatric/Neonatal Intensive Care Unit in Johannesburg, South Africa was almost double that in a dedicated paediatric intensive care unit in the same country. This study aimed to compare the raw mortality rate with that predicted with the Paediatric Index of Mortality (version 3), by doing a retrospective analysis of an existing database. RESULTS: A total of 530 patients admitted to the intensive care unit between 1 January 2015 and 31 December 2017 were included...
November 26, 2018: BMC Research Notes
Ilaria de Barbieri, Eugenia de Anna, Veronica Strini
AIM: The purpose of this review is to describe acoustic pollution in neonatal and paediatric intensive care units, sources and effects of noise on patients and health care professions and interventions to reduce it. METHOD: The literature review was carried out using four main databanks from November 2016 to December 2016 through variously combined keywords and Mesh. 237 papers were detected. Presence of full text and pertinence were selection criteria. OUTCOME: 43 papers and 2 guidelines were selected...
July 2018: Professioni Infermieristiche
Yin Ba, Jin Xu, Lin Yuan, Haiyan Zhu, Yipei Yang, Mei Mei Lam, Shulian Zhang, Mili Xiao, Jiayin Xu, Rong Zhang, Chao Chen
Objective: To validate a three-step protocol that assesses the clinical risk associated with using blood glucose monitoring systems (BGMS) in neonates for the management of dysglycaemia. Method: The three-step validation approach included confirmation of the accuracy of the reference method using National Institute of Standards and Technology (NIST) glucose standards, assessment of analytical risk performed on whole blood collected from paediatric patients routinely tested for glucose and a clinical risk assessment performed using heel stick capillary samples collected from 147 new-born babies and neonates admitted to intensive care...
2018: BMJ Paediatrics Open
Santosh Upadhyaya Kafle, Gaurav Kattel, Tanchona Nembang, Smriti Karki
INTRODUCTION: Blood component separation facility began dispatching its blood component units from 21st April 2013 at the new blood component separation service complex at B.P. Koirala Institute of Health Sciences. With the supply of blood components being finite and with the added recognition of a high rate of inappropriate use of blood component services around the world, there is a need to monitor and regulate these services. Our study was conducted to identify blood component utilization pattern in institute and to know about different blood components demand for future preparedness...
March 2018: JNMA; Journal of the Nepal Medical Association
Eszter Nagy, Nelli Farkas, Katalin Hollódy
Background and purpose: Differential diagnosis of neonatal and infantile seizures based only on inspection poses a challenge even for specialists. Aims - To investigate the evaluations of neonatal and infantile paroxysmal events based only on inspection. Research question - Is there any difference in the opinion of neonatologists, paediatric neurologists and neurologists about the assessment of common paroxysmal events in infancy? Methods: Video recordings about paroxysmal movements of 15 neonates or infants (aged 2 days- 5 months) were displayed for 47 paediatric neurologists, 35 neonatologists and nurses working in Neonatal or Perinatal Intensive Care Units and 43 neurologists...
September 30, 2018: Ideggyógyászati Szemle
Malcolm R Battin, Christopher Jd McKinlay
AIM: The aim was to survey the Australian and New Zealand Neonatal Network (ANZNN) member units regarding current services and management guidelines for the ex-premature infant with severe chronic lung disease (CLD) still requiring significant respiratory support at term. METHODS: A 16-question survey was sent to clinical directors of all Level 3 units in Australia and New Zealand via the network. Reminder emails were sent, as required, to prompt a satisfactory response rate...
October 10, 2018: Journal of Paediatrics and Child Health
Elisabeth Segers, Henrietta Ockhuijsen, Petra Baarendse, Irene van Eerden, Agnes van den Hoogen
OBJECTIVE: To explore the impact of family centred care interventions on parents' satisfaction and length of stay for patients admitted to a paediatric intensive care unit or a neonatal intensive care unit. METHODS: A systematic review was conducted. Searches have been done in Cinahl, Cochrane, Embase and PubMed from February 2016 till October 2017. All included studies were quality appraised. Due to the heterogeneity of interventions findings were narratively reviewed...
September 21, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Sören Verstraete, Sascha C Verbruggen, José A Hordijk, Ilse Vanhorebeek, Karolijn Dulfer, Fabian Güiza, Esther van Puffelen, An Jacobs, Sandra Leys, Astrid Durt, Hanna Van Cleemput, Renate D Eveleens, Gonzalo Garcia Guerra, Pieter J Wouters, Koen F Joosten, Greet Van den Berghe
BACKGROUND: The paediatric early versus late parenteral nutrition in critical illness (PEPaNIC) multicentre, randomised, controlled trial showed that, compared with early parenteral nutrition, withholding supplemental parenteral nutrition for 1 week in the paediatric intensive care unit (PICU; late parenteral nutrition) reduced infections and accelerated recovery from critical illness in children. We aimed to investigate the long-term impact on physical and neurocognitive development of early versus late parenteral nutrition...
September 14, 2018: Lancet Respiratory Medicine
Shamala Balan, Mohamed Azmi Ahmad Hassali, Vivienne S L Mak
BACKGROUND: In the past two decades, many legislative and regulatory initiatives were taken globally to improve drug use in children. However, children are still found to be prescribed with off-label drugs. This study was conducted to provide an overview of the worldwide trend in off-label prescribing in children from the year 1996 to 2016. DATA SOURCES: The articles published in PubMed, MEDLINE and Google Scholar were searched using text words: off-label, unlicensed, paediatric and children...
September 14, 2018: World Journal of Pediatrics: WJP
Zeynep Ozkurt, Selahattin Balsak, Yusuf Yildirim, Harun Yuksel, Ihsan Caca
Background: Red reflex screening is the primary but unheeded test for the detection of vision- and life-threatening eye conditions. Aims: To evaluate the red reflex of newborns, percentage of ocular diseases resulting in red reflex abnormality, and their relation with consanguinity in Southeast Turkey. Methods: Newborns (n = 1358) were examined with pencil light and direct ophthalmoscopy. Results: Eight hundred of these newborns were hospitalized in a rooming-in unit...
September 6, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
Ioannis N Mammas, Demetrios A Spandidos
Professor Alan Michael Weindling, Emeritus Professor of Perinatal Medicine at the University of Liverpool in the UK, is one of the pioneers of modern neonatal care worldwide with an enormous contribution to the care of premature babies in the city of Liverpool. During the last 3 decades, his contributions focused on the development of the clinical service, the training provided and the strong research achievements at Liverpool Women's Hospital NHS Trust, one of the most widely respected centres for neonatal medicine in western Europe...
September 2018: Experimental and Therapeutic Medicine
Ioannis N Mammas, Demetrios A Spandidos
Dr Prakash Thiagarajan, consultant neonatologist and clinical director at Women's and Children's Division at Noble's Hospital on the Isle of Man, is one of the most talented neonatologists in the UK with a great experience in newer modes of infant ventilation and the application of technology in neonatal medicine and paediatrics. Under his leadership, the new neonatal intensive care unit (NICU) at Noble's Hospital is a state-of-the-art neonatal unit offering the very highest standards of care for critically ill babies on the island...
September 2018: Experimental and Therapeutic Medicine
Mark Corbett, David Marshall, Melissa Harden, Sam Oddie, Robert Phillips, William McGuire
BACKGROUND: Extravasation injuries are caused by unintended leakages of fluids or medicines from intravenous lines, but there is no consensus on the best treatment approaches. OBJECTIVES: To identify which treatments may be best for treating extravasation injuries in infants and young children. DESIGN: Scoping review and survey of practice. POPULATION: Children aged < 18 years with extravasation injuries and NHS staff who treat children with extravasation injuries...
August 2018: Health Technology Assessment: HTA
Esther van Puffelen, Ilse Vanhorebeek, Koen F M Joosten, Pieter J Wouters, Greet Van den Berghe, Sascha C A T Verbruggen
BACKGROUND: Previous randomised studies showed that withholding parenteral nutrition for 1 week of critical illness was superior to early initiation (<24-48 h) of parenteral nutrition in children and adults. However, neonates are considered more susceptible to macronutrient deficits. We investigated the effect of withholding parenteral nutrition for 1 week in critically ill, term neonates. METHODS: We previously did a randomised, controlled study (PEPaNIC) of children aged up to 17 years admitted to paediatric intensive-care units (ICUs) in three hospitals in Belgium, Canada, and the Netherlands randomly assigned (1:1) to either standard care of parenteral nutrition initiated early within 24 h of admission to an ICU or late parenteral nutrition (where supplemental parenteral nutrition was withheld for 1 week after admission to the ICU)...
July 2018: The lancet child & adolescent health
Nilesh M Mehta, Robert C Tasker
No abstract text is available yet for this article.
July 2018: Lancet Child & Adolescent Health
Philipp K A Agyeman, Luregn J Schlapbach, Eric Giannoni, Martin Stocker, Klara M Posfay-Barbe, Ulrich Heininger, Matthias Schindler, Insa Korten, Gabriel Konetzny, Anita Niederer-Loher, Christian R Kahlert, Alex Donas, Antonio Leone, Paul Hasters, Christa Relly, Walter Baer, Claudia E Kuehni, Christoph Aebi, Christoph Berger
BACKGROUND: Sepsis is a leading cause of childhood mortality worldwide. We assessed population-based incidence and outcomes of blood culture-proven bacterial sepsis in children in Switzerland. METHODS: We did a multicentre, prospective, cohort study at ten paediatric hospitals in Switzerland. We included neonates and children younger than 17 years with blood culture-proven bacterial sepsis. Children were eligible if they met criteria for systemic inflammatory response syndrome-according to 2005 paediatric consensus definition- at the time of blood culture sampling...
October 2017: Lancet Child & Adolescent Health
Anand Wagh, Ajay Sinha
INTRODUCTION: Healthcare-associated infections put a tremendous burden on health services around. In the last few decades, there has been a tremendous advancement in foetal and maternal care, and it has led to premature babies born as early as 25 weeks of gestation being nursed and cared for in neonatal and paediatric intensive care units. However, these children can pick up a number of uncommon and rare hospital-acquired infections including central nervous system (CNS) infections. METHODS: The authors have given their own insight as to the prevention of healthcare-associated infections in paediatric intensive care settings and reviewed the current literature on the topic...
October 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
K E Foy, E Mew, T M Cook, J Bower, P Knight, S Dean, K Herneman, B Marden, F E Kelly
In 2011, the Fourth National Audit Project (NAP4) reported high rates of airway complications in adult intensive care units (ICUs), including death or brain injury, and recommended preparation for airway difficulty, immediately available difficult airway equipment and routine use of waveform capnography monitoring. More than 80% of UK adult intensive care units have subsequently changed practice. Undetected oesophageal intubation has recently been listed as a 'Never Event' in UK practice, with capnography mandated...
August 15, 2018: Anaesthesia
G Elias, A Souquette, S Heynderickx, I De Meester, H Jansens, P Beutels, P Van Damme, E Smits, P G Thomas, V Van Tendeloo, B Ogunjimi
Pathogen exposure, including but not limited to herpesviruses, moulds the shape of the immune system, both at a basal state and in response to immune challenge. However, little is known about the impact of high exposure to other viruses on baseline immune signatures and how the immune system copes with repetitive exposures to maintain a balanced functionality. Here we investigated baseline immune signatures, including detailed T cell phenotyping, antigen-specific CD4+ and CD8+ T cell responses and cytokine profile in paediatric (PED) nurses, who have high occupational exposure to viral pathogens including varicella zoster virus (VZV) and respiratory viruses, and in neonatal intensive care unit (NICU) nurses, as a control group with infrequent occupational exposure...
November 2018: Clinical and Experimental Immunology
Thorunn Oskarsdottir, David Harris, Adam Sutherland, Andrew Wignell, Nanna Christiansen
OBJECTIVES: This study aimed to explore the use of standard concentration infusions for intravenous infusions (SCI) in paediatric and neonatal units in the United Kingdom (UK). This included how many units use SCI, variation and overlap in concentrations, devices in use for administration and how the infusions were provided. METHODS: Paediatric and neonatal units in the UK were surveyed using a self-administered web-based survey tool. Respondents were accessed through professional networks over a one-month period in summer 2016...
October 2018: Journal of Pharmacy and Pharmacology
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