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humidified high flow oxygen

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https://www.readbyqxmd.com/read/30488718/therapeutic-strategies-for-pediatric-bronchiolitis
#1
Matti Korppi
Bronchiolitis in infancy is the most common infectious reason for hospitalization of infants without any chronic underlying illness. Areas covered: This review focuses on the role of racemic epinephrine, systemic corticosteroids, hypertonic saline and high-flow oxygen therapy (HFOT) in the treatment of infants with bronchiolitis. Literature was searched from Pubmed covering the years 2009-2018 using the entries of bronchiolitis or viral bronchiolitis, and epinephrine, adrenaline, racemic epinephrine, racemic adrenaline, corticosteroids, hypertonic saline, high-flow oxygen therapy or high-flow oxygen cannula...
November 29, 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/30475239/apneic-oxygenation-with-high-flow-nasal-cannula-and-transcutaneous-carbon-dioxide-monitoring-during-airway-surgery-a-case-series
#2
Callie Gittemeier Ebeling, Christina Anne Riccio
Three patients underwent laryngeal and tracheal surgeries under apneic conditions using transnasal humidified rapid-insufflation ventilatory exchange. Transcutaneous carbon dioxide (CO2) levels were recorded throughout the apneic period to detect rates of CO2 rise. Conventional airway management was initiated after 15 minutes of apnea with either tracheal intubation or jet ventilation. No patient experienced oxygen desaturation <97%. The average rate of transcutaneous CO2 rise (1.7 mm Hg/min) was higher than previously reported using this technique...
November 20, 2018: A&A practice
https://www.readbyqxmd.com/read/30451100/feasibility-of-high-flow-nasal-cannula-implementation-for-children-with-acute-lower-respiratory-tract-disease-in-rural-kenya
#3
Amélie O Von Saint André-Von Arnim, Bob Okeyo, Nathan Cook, Mardi Steere, Joan Roberts, Christopher R A Howard, Larissa I Stanberry, Grace C John-Stewart, Arianna Shirk
BACKGROUND: High-flow nasal cannula (HFNC) is a well-established respiratory support device in high-income countries, but to our knowledge, its use in sub-Saharan Africa has not been reported. This feasability study describes the implementation process of HFNC in rural Kenya. METHODS: HFNC was implemented in intensive care and high dependency units at Kijabe Hospital, Kenya for children with acute lower respiratory disease. Rate of intubation was compared with historical controls and challenges of implementation described...
November 19, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/30418838/the-role-of-high-flow-nasal-oxygen-therapy-in-anaesthesia
#4
David Kotwinski, Laura Paton, Roger Langford
The delivery of oxygen is a key component of anaesthetic practice. High flow nasal oxygen therapy is a relatively new addition to more traditional means of oxygenation which provides heated and humidified flows of controlled oxygen/air mixes achieving rates of up to 120 litres/min. The physiological benefits include nasopharyngeal dead space washout, reduced work of breathing, alveolar recruitment, maintained mucociliary function and the ability to provide apnoeic oxygenation. This article considers the current evidence for high flow nasal oxygen therapy in perioperative anaesthetic care during pre-oxygenation and intubation, management of the difficult airway, oxygenation for shared airway surgery, extubation and postoperative support, obstetric and paediatric anaesthesia...
November 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/30374754/work-of-breathing-during-hhhfnc-and-synchronised-nippv-following-extubation
#5
Elinor Charles, Katie A Hunt, Gerrard F Rafferty, Janet L Peacock, Anne Greenough
Our aim was to compare the work of breathing (WOB) during synchronised nasal intermittent positive pressure ventilation (SNIPPV) and heated humidified high flow nasal cannula (HHHFNC) when used as post-extubation support in preterm infants. A randomised crossover study was undertaken of nine infants with a median gestational age of 27 (range 24-31) weeks and post-natal age of 7 (range 2-50) days. Infants were randomised to either SNIPPV or HHHFNC immediately following extubation. They were studied for 2 h on one mode and then switched to the other modality and studied for a further 2-h period...
October 30, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/30362695/medical-devices-anesthesiology-devices-classification-of-the-high-flow-humidified-oxygen-delivery-device-final-order
#6
(no author information available yet)
The Food and Drug Administration (FDA or we) is classifying the high flow humidified oxygen delivery device into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the high flow humidified oxygen delivery device's classification. We are taking this action because we have determined that classifying the device into class II (special controls) will provide a reasonable assurance of safety and effectiveness of the device...
October 26, 2018: Federal Register
https://www.readbyqxmd.com/read/30324221/heated-humidified-high-flow-nasal-oxygen-prevents-intraoperative-body-temperature-decrease-in-non-intubated-thoracoscopy
#7
C J Lai, K C Yeh, M L Wang, W H Tai, Ya-Jung Cheng
PURPOSE: In patients receiving non-intubated video-assisted thoracic surgery (NIVATS), transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) has been applied instead of oxygen mask for better oxygenation. However, the THRIVE effects on intraoperative temperature decrease have not been investigated. METHODS: Pre- and postoperative temperatures, measured by an infrared tympanic ear thermometer, taken before sending patients to the operation room and immediately upon their arrival in the postoperative anesthesia unit, were collected from medical records of patients who received NIVATS either with oxygen mask or THRIVE...
December 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/30309381/high-flow-oxygen-via-tracheostomy-facilitates-weaning-from-prolonged-mechanical-ventilation-in-patients-with-restrictive-pulmonary-dysfunction-two-case-reports
#8
Chieko Mitaka, Masahiko Odoh, Daizoh Satoh, Tadasuke Hashiguchi, Eiichi Inada
BACKGROUND: Weaning from prolonged mechanical ventilation is extremely difficult in tracheostomized patients with restrictive pulmonary dysfunction. High-flow oxygen via tracheostomy supplies heated and humidified oxygen gas at > 10 L/minute. However, little has been reported on the use of high-flow oxygen via tracheostomy during weaning from ventilators in patients with restrictive pulmonary dysfunction. We report successful weaning from ventilators in patients with restrictive pulmonary dysfunction using high-flow oxygen via tracheostomy...
October 12, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/30232113/comparison-of-high-flow-nasal-cannula-oxygen-and-conventional-oxygen-therapy-on-ventilatory-support-duration-during-acute-on-chronic-respiratory-failure-study-protocol-of-a-multicentre-randomised-controlled-trial-the-high-flow-acrf-study
#9
Jean-Damien Ricard, Fadia Dib, Marina Esposito-Farese, Jonathan Messika, Christophe Girault
INTRODUCTION: This study protocol describes a trial designed to investigate whether high-flow heated and humidified nasal oxygen (HFHO) therapy in patients with hypercapnic acute respiratory failure (ARF) reduces the need of non-invasive ventilation (NIV). METHODS AND ANALYSIS: This is an open-label, superiority, international, parallel-group, multicentre randomised controlled two-arm trial, with an internal feasibility pilot phase. 242 patients with hypercapnic ARF requiring NIV admitted to an intensive care unit, an intermediate care or a respiratory care unit will be randomised in a 1:1 ratio to receive HFHO or standard oxygen in between NIV sessions...
September 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/30111466/-comparison-of-clinical-efficacy-of-two-noninvasive-respiratory-support-therapies-for-respiratory-distress-syndrome-in-very-low-birth-weight-preterm-infants
#10
Zhu Wang, Jian-Wen Xiang, Wei-Wei Gao, Yong-Zhen Shen, Wen-Ji Zhou, Jia Chen, Fang Xu, Jie Yang
OBJECTIVE: To compare the clinical efficacy of nasal intermittent positive pressure ventilation (NIPPV) and heated humidified high flow nasal cannula (HHHFNC) in the treatment of respiratory distress syndrome (RDS) among very low birth weight (VLBW) preterm infants. METHODS: A total of 89 very low birth weight premature infants with respiratory distress syndrome (RDS) who were randomly administered with NIPPV (n=46) and HHHFNC (n=43) as an initial respiratory support...
August 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/30020104/novel-preoxygenation-technique-to-deliver-high-flow-oxygen-in-a-patient-with-facial-trauma-a-case-report
#11
Verna M Aykanat, Desmond P McGlade
This case demonstrates a novel preoxygenation technique in a patient with difficult access to the airway after a traumatic facial injury. To find a solution, a fusion of oxygenation equipment was trialed by altering and combining a tracheostomy mask and the tubing of an Optiflow circuit from which the nasal cannula component had been removed. This novel combination delivered high-flow humidified oxygen (60 L/min) orally, avoided further facial injury, and was well tolerated by the patient. Effective preoxygenation was confirmed by arterial gas measurements...
July 16, 2018: A&A practice
https://www.readbyqxmd.com/read/29966108/the-use-of-transnasal-humidified-rapid-insufflation-ventilatory-exchange-thrive-for-pre-oxygenation-in-neurosurgical-patients-a-randomised-controlled-trial
#12
RANDOMIZED CONTROLLED TRIAL
I Ng, R Krieser, P Mezzavia, K Lee, C Tseng, Nwr Douglas, R Segal
This study explored the use of high-flow nasal oxygen (HFNO) in both pre-oxygenation and apnoeic oxygenation in adults who were intubated following a non-rapid sequence induction. Fifty patients were randomised to receive pre-oxygenation via a standard facemask or the Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) device. After five minutes of pre-oxygenation, induction and muscle relaxant agents were given. While waiting for complete paralysis, patients in the standard facemask group received bag-mask ventilation (BMV), whereas patients in the HFNO group received apnoeic oxygenation via the THRIVE device...
July 2018: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29743098/impact-of-flow-and-temperature-on-patient-comfort-during-respiratory-support-by-high-flow-nasal-cannula
#13
RANDOMIZED CONTROLLED TRIAL
Tommaso Mauri, Alessandro Galazzi, Filippo Binda, Laura Masciopinto, Nadia Corcione, Eleonora Carlesso, Marta Lazzeri, Elena Spinelli, Daniela Tubiolo, Carlo Alberto Volta, Ileana Adamini, Antonio Pesenti, Giacomo Grasselli
BACKGROUND: The high-flow nasal cannula (HFNC) delivers up to 60 l/min of humidified air/oxygen blend at a temperature close to that of the human body. In this study, we tested whether higher temperature and flow decrease patient comfort. In more severe patients, instead, we hypothesized that higher flow might be associated with improved comfort. METHODS: A prospective, randomized, cross-over study was performed on 40 acute hypoxemic respiratory failure (AHRF) patients (PaO2 /FiO2  ≤ 300 + pulmonary infiltrates + exclusion of cardiogenic edema) supported by HFNC...
May 9, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29713153/long-term-effects-of-oxygen-enriched-high-flow-nasal-cannula-treatment-in-copd-patients-with-chronic-hypoxemic-respiratory-failure
#14
RANDOMIZED CONTROLLED TRIAL
Line Hust Storgaard, Hans-Ulrich Hockey, Birgitte Schantz Laursen, Ulla Møller Weinreich
Background: This study investigated the long-term effects of humidified high-flow nasal cannula (HFNC) in COPD patients with chronic hypoxemic respiratory failure treated with long-term oxygen therapy (LTOT). Patients and methods: A total of 200 patients were randomized into usual care ± HFNC. At inclusion, acute exacerbation of COPD (AECOPD) and hospital admissions 1 year before inclusion, modified Medical Research Council (mMRC) score, St George's Respiratory Questionnaire (SGRQ), forced expiratory volume in 1 second (FEV1 ), 6-minute walk test (6MWT) and arterial carbon dioxide (PaCO2 ) were recorded...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29694995/respiratory-support-in-bronchiolitis-trial-evidence
#15
Steve Cunningham
Acute viral lower respiratory tract infection is frequently associated with hypoxemia and respiratory distress, sometimes progressing to hypercarbia and respiratory failure. In recent years, trials have assessed the effects of oxygen supplementation and respiratory support with high-flow oxygen therapy. An oxygen saturation target of 90% is as safe and clinically effective as 94% in infants with bronchiolitis. Trials of high-flow humidified oxygen have demonstrated safety, but as yet poorly demarcated an appropriate place for use within the clinical course of the disease...
May 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29643554/effectiveness-of-transnasal-humidified-rapid-insufflation-ventilatory-exchange-versus-traditional-preoxygenation-followed-by-apnoeic-oxygenation-in-delaying-desaturation-during-apnoea-a-preliminary-study
#16
Sunil Rajan, Nandhini Joseph, Pulak Tosh, Dilesh Kadapamannil, Jerry Paul, Lakshmi Kumar
Background and Aims: Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) during apnoea has shown to delay desaturation. The primary objective was to compare time to desaturate to <90% during apnoea with THRIVE versus traditional preoxygenation followed by apnoeic oxygenation. Methods: This prospective, randomised, single-blinded study was conducted in 10 adult patients presenting for direct laryngoscopy under general anaesthesia without endotracheal intubation...
March 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29607161/effectiveness-of-high-flow-nasal-cannula-oxygen-therapy-for-acute-respiratory-failure-with-hypercapnia
#17
Eun Sun Kim, Hongyeul Lee, Se Joong Kim, Jisoo Park, Yeon Joo Lee, Jong Sun Park, Ho Il Yoon, Jae Ho Lee, Choon-Taek Lee, Young-Jae Cho
Background: Heated and humidified high-flow nasal cannula (HFNC) oxygen therapy has recently been introduced for hypoxic respiratory failure. However, it has not been well-evaluated for acute respiratory failure with hypercapnia. Methods: This retrospective study included acute respiratory failure patients with hypercapnia in the medical intensive care unit (MICU) from April 2011 to February 2013, who required HFNC oxygen therapy for hypoxemia. Respiratory parameters were recorded and arterial blood gas analyses conducted before, and at 1 and 24 h after initiation of HFNC oxygen therapy...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29544721/dexmedetomidine-high-flow-nasal-oxygen-and-sugammadex-reversal-of-rocuronium-overcoming-anaesthetic-challenges-in-a-parturient-with-congenital-muscular-dystrophy-presenting-for-caesarean-section
#18
M Creaney, R M Moriarty, M Milner, C Murphy
Congenital muscular dystrophies are characterised by progressive skeletal muscle weakness from birth or early infancy. Maternal respiratory compromise, joint contractures and presence of spinal instrumentation or fusion are some of the anaesthetic challenges that may be encountered in the obstetric setting. The choice of anaesthetic technique for surgical delivery needs to be considered on an individual basis. Multidisciplinary involvement is paramount to optimise peripartum care and outcomes. In this case report, we present the use of dexmedetomidine, humidified high-flow nasal oxygen, rocuronium and sugammadex in the anaesthetic management of a wheelchair-bound, non-invasive bilevel positive airway pressure ventilation-dependent parturient with congenital muscular dystrophy, who was presenting for caesarean section...
May 2018: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/29531447/comparative-study-between-noninvasive-continuous-positive-airway-pressure-and-hot-humidified-high-flow-nasal-cannulae-as-a-mode-of-respiratory-support-in-infants-with-acute-bronchiolitis-in-pediatric-intensive-care-unit-of-a-tertiary-care-hospital
#19
Mihir Sarkar, Rajasree Sinha, Satyabrata Roychowdhoury, Sobhanman Mukhopadhyay, Pramit Ghosh, Kalpana Dutta, Shibarjun Ghosh
Background: Early initiation of appropriate noninvasive respiratory support is utmost important intervention to avoid mechanical ventilation in severe bronchiolitis. Aim: This study aims to compare noninvasive continuous positive airway pressure (nCPAP) and hot humidified high-flow nasal cannulae (HHHFNC) as modes of respiratory support in infants with severe bronchiolitis. Methods: Prospective, randomized, open-label pilot study done in a tertiary-care hospital Pediatric Intensive Care Unit (PICU)...
February 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29506579/high-flow-nasal-oxygen-vs-standard-oxygen-therapy-in-immunocompromised-patients-with-acute-respiratory-failure-study-protocol-for-a-randomized-controlled-trial
#20
Elie Azoulay, Virginie Lemiale, Djamel Mokart, Saad Nseir, Laurent Argaud, Frédéric Pène, Loay Kontar, Fabrice Bruneel, Kada Klouche, François Barbier, Jean Reignier, Anabelle Stoclin, Guillaume Louis, Jean-Michel Constantin, Julien Mayaux, Florent Wallet, Achille Kouatchet, Vincent Peigne, Pierre Perez, Christophe Girault, Samir Jaber, Johanna Oziel, Martine Nyunga, Nicolas Terzi, Lila Bouadma, Christine Lebert, Alexandre Lautrette, Naike Bigé, Jean-Herlé Raphalen, Laurent Papazian, Antoine Rabbat, Michael Darmon, Sylvie Chevret, Alexandre Demoule
BACKGROUND: Acute respiratory failure (ARF) is the leading reason for intensive care unit (ICU) admission in immunocompromised patients. High-flow nasal oxygen (HFNO) therapy is an alternative to standard oxygen. By providing warmed and humidified gas, HFNO allows the delivery of higher flow rates via nasal cannula devices, with FiO2 values of nearly 100%. Benefits include alleviation of dyspnea and discomfort, decreased respiratory distress and decreased mortality in unselected patients with acute hypoxemic respiratory failure...
March 5, 2018: Trials
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