Ji-Su Shim, Hyunkyoung Kim, Jae-Woo Kwon, So-Young Park, Sujeong Kim, Byung-Keun Kim, Young-Hee Nam, Min-Suk Yang, Mi-Yeong Kim, Sae-Hoon Kim, Byung-Jae Lee, Taehoon Lee, Sang-Ha Kim, So Young Park, Young-Joo Cho, Chan Sun Park, Jae-Woo Jung, Han-Ki Park, Joo-Hee Kim, Jeong-Hee Choi, Ji-Yong Moon, Ian Adcock, Kian Fan Chung, Min-Hye Kim, Tae-Bum Kim
BACKGROUND: Despite the increasing use of biologics in severe asthma, there is limited research on their use in asthma-chronic obstructive pulmonary disease overlap (ACO). We compared real-world treatment responses to biologics in ACO and asthma. METHODS: We conducted a multicenter, retrospective, cohort study using data from the Precision Medicine Intervention in Severe Asthma (PRISM). ACO was defined as post-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) <0...
December 2023: World Allergy Organization Journal