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Supradiaphragmatic Lymph Node Metastases AND ovarian Cancer

L J McIntosh, A C O'Neill, S Bhanusupriya, S A Matalon, A D Van den Abbeele, N H Ramaiya, A B Shinagare
PURPOSE: To identify the optimal size threshold and to assess the prognostic significance of supradiaphragmatic lymph nodes at initial presentation of patients with high-grade serous ovarian cancer (HGSC). METHODS: This IRB-approved, HIPAA-compliant retrospective study included baseline pretreatment staging abdominal CTs of 88 women (mean age 62 years, SD 10.4, range 29-85) with FIGO stage III HGSC. Patients with stage IV disease were excluded due to worse prognosis and management guided by distant metastases...
October 2017: Abdominal Radiology
Johanna Hynninen, Annika Auranen, Olli Carpén, Kirsti Dean, Marko Seppänen, Jukka Kemppainen, Maija Lavonius, Irina Lisinen, Johanna Virtanen, Seija Grénman
OBJECTIVE: Epithelial ovarian cancer (EOC) spreads intra-abdominally and to the retroperitoneal lymph nodes. A greater number of distant metastases are revealed by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) compared to conventional imaging methods. We aimed to investigate the presence and anatomic distribution of supradiaphragmatic lymph node metastasis (LNM) detected with pretreatment FDG PET/CT. METHODS: Thirty women with advanced stage (IIC-IV) EOC were scanned with whole body contrast-enhanced FDG PET/CT prior to surgery/neoadjuvant chemotherapy...
July 2012: Gynecologic Oncology
Tommaso Susini, Simone Olivieri, Cecilia Molino, Francesca Castiglione, Ketty Tavella, Riccardo Viligiardi
BACKGROUND: Ovarian cancer usually spreads intra-abdominally. Supradiaphragmatic metastases are rare, and axillary lymph node metastases are exceptional. Here, we present the first case of ovarian carcinoma detected at screening mammogram as intramammary lymph node metastases. CASE REPORT: A 44-year-old obese woman underwent core biopsy of a suspicious mammographic finding histologically consistent with lymph node metastases from breast cancer. Serum tumor markers, including CA 125, were normal, and clinical staging was negative...
January 2010: Journal of Women's Health
V Ozmen, O Asoglu, H Karanlik, N Cabioglu, M Kecer, H Bakkaloglu
BACKGROUND: Axillary lymph node metastasis of primary ovarian cancer is rare. CASE I: A 74-year-old woman presented with a 2 x 2 cm hard, mobile mass in the right axilla. She had a history of stage IIIA epithelial ovarian cancer which was diagnosed and treated four years previously. A right lateral wall involvement of the rectum was detected in abdominal tomography. A right axillary lymph node dissection and low anterior resection of the rectum were performed. Histopathologic examination showed ovarian epithelial serous papillary adenocarcinoma metastases to axillary lymph node and the rectum...
January 2007: Acta Chirurgica Belgica
S V Patel, J A Spencer, N Wilkinson, T J Perren
AIM: To illustrate unusual patterns of isolated supradiaphragmatic presentation and relapse of papillary serous adenocarcinoma of the ovary. METHODS: Retrospective study of five women (26-57 years) managed by a specialist gynaecological oncology unit. RESULTS: Three women relapsed in the neck, mediastinal or axillary nodes 3 to 5 years after complete abdomino-pelvic remission. Two women presented with pleural or cervical lymph node metastases respectively 2 and 13 years before the primary pelvic tumour was discovered...
November 1999: Clinical Radiology
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