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https://www.readbyqxmd.com/read/30534659/reasons-for-inadequate-or-incomplete-imaging-techniques
#1
REVIEW
Cosmin Caraiani, Yi Dong, Anthony G Rudd, Christoph F Dietrich
Even if imaging has developed considerably during the last decades there still exist several factors which limit its capacities. These factors can either limit the usage of a technique or degrade images making them difficult to interpret. Magnetic resonance imaging (MRI) has, as an absolute contraindication, the presence of metallic devices marked as "MRI unsafe" and metallic foreign bodies close to the eye or vital structures. Claustrophobia and artefacts reduce the application and performance of MRI in a significant proportion of patients...
December 8, 2018: Medical Ultrasonography
https://www.readbyqxmd.com/read/30532305/functional-ultrasonography-in-diagnosing-anterior-cruciate-ligament-injury-as-compared-to-magnetic-resonance-imaging
#2
Sudeep Kumar, Anup Kumar, Subhash Kumar, Prem Kumar
Background: Magnetic resonance imaging (MRI) has been gold standard investigation for diagnosing anterior cruciate ligament (ACL) tear. Availability and cost are two main factors limiting the universal use of MRI in all those patients in whom ligament injury is suspected. We compared the outcome of functional USG with gold standard MRI scan in this prospective study. Materials and Methods: In this study, we included the patients coming to orthopedics outpatient department with sign and symptoms of ACL injury...
November 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/30523911/synthesis-of-gadolinium-based-bi-sub-2-sub-s-sub-3-sub-nanoparticles-as-cancer-theranostics-for-dual-modality-computed-tomography-magnetic-resonance-imaging-guided-photothermal-therapy
#3
HongYing Guo, Xiaoshuang Zhao, Hongmei Sun, Hongda Zhu, Honghao Sun
Development of a safe, efficient and inexpensive multifunctional nanoplatform using a facile approach for multimodal imaging and therapeutic functions becomes more and more practically relevant but challenging. In this work, we demonstrated a novel nanocomposites (Bi2S3-Gd) for computed tomography (CT)/magnetic resonance (MR) imaging-guided photothermal therapy for cancer in vitro. It was achieved by modification of hydrophobic Bi2S3 with a smart amphiphilic gadolinium-chelated ligand. The as-prepared nanocomposites composed of low cost Bi2S3 and gadolinium complexes, showed high stability, excellent biocompatibility and good photostability...
November 27, 2018: Nanotechnology
https://www.readbyqxmd.com/read/30510883/the-utility-of-magnetic-resonance-imaging-compatible-pacemakers-in-neurosurgical-patients
#4
Gregory Basil, Karthik Madhavan, Ricardo J Komotar, Roger Carrillo, Allan D Levi
Artificial implantable pacemakers have long been a challenge to neurosurgeons seeking to perform advanced diagnostic imaging on their patients. Unfortunately, while the use of implantable pacemakers has been a life-saving advance for those with cardiac arrhythmias, they also often prevent these patients from undergoing magnetic resonance imaging (MRI). There have been multiple reported cases of pacemaker failure in the context of MRI use. Recent technological advances, however, have allowed the development of pacemakers that are not affected by the MRI scanner...
September 27, 2018: Curēus
https://www.readbyqxmd.com/read/30506866/novel-short-peripheral-catheter-design-for-prevention-of-thrombophlebitis
#5
Dar Weiss, Halit Yaakobovitch, Sigal Tal, Abraham Nyska, Oren M Rotman
BACKGROUND: Short peripheral catheters (SPCs) are the most common intravenous device in today's medical practice. Short peripheral catheter thrombophlebitis (SPCT) occurs in up to 80% of hospitalized patients. symptoms appear on average 3 days after catheter insertion and can lead to extended hospitalization and increased related costs. Here we introduce a novel SPC, named Very Short Peripheral Catheter(VSPC), that was designed to minimize biomechanical irritation and improve blood flow...
December 2, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/30488309/template-for-mr-visualization-and-needle-targeting
#6
Rui Li, Sheng Xu, Ivane Bakhutashvili, Ismail B Turkbey, Peter Choyke, Peter Pinto, Bradford Wood, Zion T H Tse
To improve the targeting accuracy and reduce procedure time in magnetic resonance imaging (MRI)-guided procedures, a 3D-printed flexible template was developed. The template was printed using flexible photopolymer resin FLFLGR02 in Form 2 printer® (Formlabs, Inc., Somerville, MA). The flexible material gives the template a unique advantage by allowing it to make close contact with human skin and provide accurate insertion with the help of the newly developed OncoNav software. At the back of the template, there is a grid comprised of circular containers filled with contrast agent...
November 28, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/30487391/the-emerging-role-of-amino-acid-pet-in-neuro-oncology
#7
REVIEW
Amer M Najjar, Jason M Johnson, Dawid Schellingerhout
Imaging plays a critical role in the management of the highly complex and widely diverse central nervous system (CNS) malignancies in providing an accurate diagnosis, treatment planning, response assessment, prognosis, and surveillance. Contrast-enhanced magnetic resonance imaging (MRI) is the primary modality for CNS disease management due to its high contrast resolution, reasonable spatial resolution, and relatively low cost and risk. However, defining tumor response to radiation treatment and chemotherapy by contrast-enhanced MRI is often difficult due to various factors that can influence contrast agent distribution and perfusion, such as edema, necrosis, vascular alterations, and inflammation, leading to pseudoprogression and pseudoresponse assessments...
November 28, 2018: Bioengineering
https://www.readbyqxmd.com/read/30486808/the-impact-of-global-budget-on-the-diffusion-of-innovations-the-example-of-positron-emission-tomography-in-taiwan
#8
Che-Ming Yang
BACKGROUND: The essence of global budget is to set a cap on the total national health insurance expenditure for a year, which is one form of prospective payment systems. It has always been argued that prospective payment, such as global budgeting, will deter the development of high-tech services in the healthcare industry. The objectives of this study are to explore the impact of global budgeting on the diffusion of high tech equipment in terms of utilization by using Positron Emission Tomography (PET) as an example...
November 29, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/30485221/restneumap-a-tool-for-automatic-extraction-of-resting-state-functional-mri-networks-in-neurosurgical-practice
#9
(no author information available yet)
OBJECTIVEResting-state functional MRI (rs-fMRI) represents a promising and cost-effective alternative to task-based fMRI for presurgical mapping. However, the lack of clinically streamlined and reliable rs-fMRI analysis tools has prevented wide adoption of this technique. In this work, the authors introduce an rs-fMRI processing pipeline (ReStNeuMap) for automatic single-patient rs-fMRI network analysis.METHODSThe authors provide a description of the rs-fMRI network analysis steps implemented in ReStNeuMap and report their initial experience with this tool after performing presurgical mapping in 6 patients...
October 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/30479744/current-evidence-for-spinal-x-ray-use-in-the-chiropractic-profession-a-narrative-review
#10
REVIEW
Hazel J Jenkins, Aron S Downie, Craig S Moore, Simon D French
The use of routine spinal X-rays within chiropractic has a contentious history. Elements of the profession advocate for the need for routine spinal X-rays to improve patient management, whereas other chiropractors advocate using spinal X-rays only when endorsed by current imaging guidelines. This review aims to summarise the current evidence for the use of spinal X-ray in chiropractic practice, with consideration of the related risks and benefits. Current evidence supports the use of spinal X-rays only in the diagnosis of trauma and spondyloarthropathy, and in the assessment of progressive spinal structural deformities such as adolescent idiopathic scoliosis...
2018: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/30479618/comparison-of-impact-of-target-delineation-of-computed-tomography-and-magnetic-resonance-imaging-guided-brachytherapy-on-dose-distribution-in-cervical-cancer
#11
Lalida Tuntipumiamorn, Suphalerk Lohasammakul, Pittaya Dankulchai, Pitchayut Nakkrasae
Purpose: The dose distributions obtained from three imaging approaches for target delineation in cervical cancer using high-dose-rate (HDR) brachytherapy were investigated. Material and methods: Ten cervical cancer patients receiving four fractions of HDR brachytherapy were enrolled. Based on different imaging approaches, three brachytherapy plans were developed for each patient: with the high-risk clinical target volume (HRCTV) delineated on magnetic resonance (MRI) images for every fraction (approach A; MRI-only); on MRI for the first fraction and computed tomography (CT) images for the subsequent fractions (approach B; MRI1st /CT); and on CT images for all fractions (approach C; CT-only)...
October 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/30477981/head-to-head-comparison-of-transrectal-ultrasound-guided-prostate-biopsy-versus-multiparametric-prostate-resonance-imaging-with-subsequent-magnetic-resonance-guided-biopsy-in-biopsy-na%C3%A3-ve-men-with-elevated-prostate-specific-antigen-a-large-prospective-multicenter
#12
Marloes van der Leest, Erik Cornel, Bas Israël, Rianne Hendriks, Anwar R Padhani, Martijn Hoogenboom, Patrik Zamecnik, Dirk Bakker, Anglita Yanti Setiasti, Jeroen Veltman, Huib van den Hout, Hans van der Lelij, Inge van Oort, Sjoerd Klaver, Frans Debruyne, Michiel Sedelaar, Gerjon Hannink, Maroeska Rovers, Christina Hulsbergen-van de Kaa, Jelle O Barentsz
BACKGROUND: There is growing interest to implement multiparametric magnetic resonance imaging (mpMRI) and MR-guided biopsy (MRGB) for biopsy-naïve men with suspected prostate cancer. OBJECTIVE: Primary objective was to compare and evaluate an MRI pathway and a transrectal ultrasound-guided biopsy (TRUSGB) pathway in biopsy-naïve men with prostate-specific antigen levels of ≥3ng/ml. DESIGN, SETTING, AND POPULATION: A prospective, multicenter, powered, comparative effectiveness study included 626 biopsy-naïve patients (from February 2015 to February 2018)...
November 23, 2018: European Urology
https://www.readbyqxmd.com/read/30477480/timing-of-physical-therapy-consultation-on-1-year-healthcare-utilization-and-costs-in-patients-seeking-care-for-neck-pain-a-retrospective-cohort
#13
Maggie E Horn, Julie M Fritz
BACKGROUND: Patients seek care from physical therapists for neck pain but it is unclear what the association of the timing of physical therapy (PT) consultation is on 1-year healthcare utilization and costs. The purpose of this study was to compare the 1-year healthcare utilization and costs between three PT timing groups: patients who consulted a physical therapist (PT) for neck pain within 14 days (early PT consultation), between 15 and 90 days (delayed PT consultation) or between 91 and 364 days (late PT consultation)...
November 26, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/30473135/assessing-non-uniform-stiffening-of-the-achilles-tendon-noninvasively-using-surface-wave
#14
Muhammad Salman, Karim G Sabra
Currently, noninvasive cost-effective techniques capable of quantifying non-uniform degradation of tendon's mechanical and structural properties associated with localized tendon injuries are not readily available. This study demonstrates the applicability of a simple surface-wave elastography (SURF-E) method for assessing the stiffness of the Achilles Tendon by measuring the propagation velocity of surface waves along the tendon in a much broader range of values than currently available Ultrasound-based or MRI-based elastography methods do...
November 15, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/30460628/clinical-factors-associated-with-mortality-within-three-months-after-radiosurgery-of-asymptomatic-brain-metastases-from-non-small-cell-lung-cancer
#15
Bina Kakusa, Summer Han, Sonya Aggarwal, Boxiang Liu, Gordon Li, Scott Soltys, Melanie Hayden Gephart
PURPOSE: Routine brain MRI surveillance frequently diagnoses small, asymptomatic brain metastases from non-small cell lung cancer (NSCLC) that are effectively treated with stereotactic radiosurgery (SRS). A subset of patients, however, may die prior to the onset of symptoms. This study identifies clinical features that distinguish neurologically-asymptomatic NSCLC brain metastases patients that die prior to routine 3 month follow-up after SRS. METHODS: Retrospective chart review from 2007 to 2017 identified 18 patients with neurologically-asymptomatic NSCLC brain metastases who died < 3 months after SRS...
November 20, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/30457247/cost-benefit-analysis-of-the-introduction-of-mp-mri-guided-biopsies-in-croatia
#16
Ivan Pezelj, Igor Tomašković, Karolina Bolanča Čulo, Luka Novosel, Miroslav Tomić, Ante Reljić, Josip Katušić, Matej Knežević, Sven Nikles, Matea Pirša, Danijel Justinic, Diana Zadravec, Boris Ružić
The objective of this study was to determine differential expression of TFF1, TFF2 and TFF3 genes and proteins in breast tumor subtypes. In addition, we investigated the correlation between TFF genes within tumor subgroups, and TFF genes with clinical and pathologic characteristics of the tumor. Study group included 122 patients with surgically removed breast tumors. Samples were investigated using qRT-PCR and immunohistochemistry. TFF1 and TFF3 genes and proteins were expressed in breast tumors, while the levels of TFF2 gene and protein expression were very low or undetectable...
October 2018: Acta Clinica Croatica
https://www.readbyqxmd.com/read/30455224/continuous-low-dose-everolimus-shrinkage-tuberous-sclerosis-complex-associated-renal-angiomyolipoma-a-48-month-follow-up-study
#17
Chang-Ching Wei, Jeng-Daw Tsai, Ji-Nan Sheu, Sung-Lang Chen, Teng-Fu Tsao, Sheng-Hui Yang, Jeng-Dau Tsai
Tuberous sclerosis complex (TSC) is a rare disease that causes multisystem benign neoplasm, induced by dysregulation of the mammalian target of the rapamycin pathway (mTOR). This study aimed to examine the effects of continuous low-dose everolimus, a potent and selective inhibitor of mTOR, on the treatment of TSC-associated renal angiomyolipoma (AML). Between July 2013 and August 2017, 11 patients with TSC-AML were enrolled for an everolimus therapy protocol. An oral everolimus dose starting at 2.5 mg daily was gradually increased to 5...
November 18, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/30450430/comparison-of-costs-and-outcomes-of-patients-presenting-with-a-rare-brainstem-syndrome
#18
Devin E Prior, Vijay Renga
In this case report we compare two patients presenting with similar symptoms of a brainstem syndrome including ataxia, dysarthria, and diplopia. Their MRIs showed hyperintense FLAIR signal changes with patchy areas of contrast enhancement within the brainstem particularly the pons and cerebellum. The broad differential diagnosis of this brainstem pathology included rhomboencephalitis, neurosarcoidosis, lymphoma, vasculitis, infection, and paraneoplastic or autoimmune process. Patient 1 had an extensive work up including CSF cytology, MRI brain spectroscopy, full body CT, cerebral angiogram, and ultimately brainstem biopsy...
December 2018: ENeurologicalSci
https://www.readbyqxmd.com/read/30444041/subtractive-non-contrast-enhanced-mri-of-lower-limb-veins-using-multiple-flow-dependent-preparation-strategies
#19
Hao Li, Andrew N Priest, Ilse Patterson, Martin J Graves, David J Lomas
PURPOSE: To evaluate the performance of acceleration-dependent vascular anatomy for non-contrast-enhanced MR venography (ADVANCE-MRV) in femoral veins and to investigate whether venous signal uniformity can be improved by applying multiple acquisitions with different flow suppressions or multiple flow suppressions in 1 acquisition. METHODS: The ADVANCE-MRV method uses flow-sensitized modules to acquire a dark-artery image set and a dark-artery vein set, which are subsequently subtracted...
November 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/30441680/a-fully-convolutional-deep-neural-network-for-lung-tumor-boundary-tracking-in-mri
#20
Nazanin Tahmasebi, Pierre Boulanger, Michelle Noga, Kumaradevan Punithakumar
Delineation of lung tumor from adjacent tissue from a series of magnetic resonance images (MRI) poses many difficulties due to the image similarities of the region of interest and surrounding area as well as the influence of respiration. However, accurate segmentation of the tumor region is essential in planning a radiation therapy to prevent healthy tissues from receiving excessive radiation. The manual delineation of the entire MRI sequence is tedious, time-consuming and costly. This study investigates how one can perform automatic tracking of tumor boundaries during radiation therapy using convolutional neural networks...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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