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Nutrition AND Immunology

Shailima Rampogu, Saravanan Parameswaran, Mary Rampogu Lemuel, Keun Woo Lee
Fenugreek (Trigonella foenum-graecum) is used as a spice throughout the world. It is known for its medicinal properties such as antidiabetic, anticarcinogenic, and immunological activities. The present study shows the properties and the nutritional quality of fenugreek seed extract and focuses on screening of active compounds in drug designing for type 2 diabetes and breast cancer. Quantitative analysis was used to calculate the percentages of protein, carbohydrates moisture, fatty acid, galactomannan, oil, and amino acid...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Chao Li, Qian Ni, Yifang Pei, Yi Ren, Yufei Feng
BACKGROUND & AIMS: We performed a meta-analysis of data from recent studies to evaluate the safety and efficacy of parenteral nutrition (PN) with structured triglyceride (STG) lipid emulsions compared to medium-chain triglyceride (MCT)/long-chain triglyceride (LCT) lipid emulsions in Chinese patients. METHODS: PubMed, Embase, Cochrane Library, China National Knowledge Internet, Wanfang, and VIP were searched for randomized controlled trials comparing STGs with MCTs/LCTs published in English or Chinese between January 1987 and October 2017...
July 25, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
O A Olateru-Olagbegi, E C Omoruyi, R A Dada, V F Edem, O G Arinola
Pregnancy places a very high demand on physical, physiological and immunological responses of females,especially when aggravated by parasitic infestation. There is strong evidence that maternal infestations with helminth haveprofound effects on immunity to helminths and other pathogens. This case-control study involved 245 pregnant women aged18-40 years (>30 weeks of gestation) recruited from three secondary level hospitals in Ibadan, Nigeria. Morning stoolsamples collected from pregnant women were examine for intestinal helminths using formol-ether concentration method...
June 30, 2018: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
Joanna Pieczyńska, Anna Prescha, Katarzyna Zabłocka-Słowińska, Katarzyna Neubauer, Adam Smereka, Halina Grajeta, Jadwiga Biernat, Leszek Paradowski
BACKGROUND: Among the complex factors that may favor the occurrence of inflammatory bowel disease (IBD), genetic, immunological and environmental initiators, including nutritional factors, are listed. So far, there have been no previous studies on the type and frequency of dietary risk factors for IBD in Poland and their effect on the nutritional status of patients. OBJECTIVES: The aim of the study was to assess the influence of the frequency and type of dietary risk factors for IBD on the nutritional status of patients with ulcerative colitis (UC) and Crohn's disease (CD)...
August 7, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Leonel N Leal, Josue M Romao, Guido J Hooiveld, Fernando Soberon, Harma Berends, Mark V Boekshoten, Michael E Van Amburgh, Javier Martín-Tereso, Michael A Steele
Performance of dairy cows can be influenced by early life nutrient supply. Adipose tissue is diet sensitive and an important component in that process as it is involved in the regulation of energetic, reproductive and immunological functions. However, it is not clear how early life nutrition alters the molecular regulation of adipose tissue in calves and potentially adult individuals. This study aimed at determining how differences in pre-weaning nutrient supply alter gene expression profiles and physiology in omental adipose tissue...
2018: PloS One
Sidikiba Sidibé, Alexandre Delamou, Mohamed Lamine Kaba, Aboubacar Sidiki Magassouba, Amara Tabaouo Samake, Yao Serge Arthur Dongo, Kadio Jean-Jacques Olivier Kadio, Sandouno Sah Dimio, Lansana Mady Camara, Stella Babalola
Whereas the HIV prevalence in Guinea is among the lowest in Africa, many PLHIV in Guinea are malnourished. This study assessed the effect of a nutritional supplementation program on body mass index and CD4 count among adult PLHIV on ART. Study participants were PLHIV who came for consultation in the study sites between May and July 2016. The data came from two sources: retrospectively from participants' medical records and interviews at the time of recruitment into the study. About six months before they were recruited into the study, some of the PLHIV started to receive a monthly nutritional supplementation consisting of Corn-Soy Blend and oil...
May 21, 2018: Journal of Public Health in Africa
Anna Teresa Palatucci, Diego Piantedosi, Valentina Rubino, Angela Giovazzino, Jacopo Guccione, Vlenia Pernice, Giuseppina Ruggiero, Laura Cortese, Giuseppe Terrazzano
Over-nutrition and obesity have been associated with impaired immunity and low-grade inflammation in humans and mouse models. In this context, a causal role for unbalanced T regulatory cell (Treg)-dependent mechanisms has been largely suggested. Obesity is the most common nutritional disorder in dogs. However, it is not defined whether canine obesity may influence circulating Treg as well as if their number variation might be associated with the occurrence of systemic inflammation. The present study investigated the immune profile of healthy adult obese dogs belonging to the Labrador Retriever breed, in comparison with the normal weight counterpart...
August 2018: Veterinary Immunology and Immunopathology
Lívia Geraldi Ferreira, Mariangela Endrighi, Karen Guttenkunst Lisenko, Maiara Rodrigues Duarte de Oliveira, Mateus Resende Damasceno, Jelieny Aparecida Claudino, Pamella Godinho Gutierres, Ana Paula Peconick, Flávia Maria de Oliveira Borges Saad, Márcio Gilberto Zangeronimo
The aim of this study was to evaluate the effects of oat beta-glucan supplementation on metabolic, physiological, immunological and nutritional variables in adult dogs. Fourteen dogs were fed a control diet or a diet supplemented with 1% beta-glucan during 71 days. Serum concentrations of glucose, total cholesterol and lipoprotein fractions, as well as plasma concentrations of peptide YY and ghrelin, were determined. In addition, coefficient of total tract apparent macronutrient digestibility (CTTAD), food intake and fecal output, score, and pH were evaluated...
2018: PloS One
Zhongwang Zhang, Jianliang Lv, Li Pan, Yongguang Zhang
Lactobacilli are recognized as probiotics on account of their health-promoting effects in the host. The aim of this review is to summarize current knowledge of the mechanisms of the adaption factors and main functions of lactobacilli that exert health-promoting effects in the host and to discuss important applications in animal and human health. The adaption mechanisms of lactobacilli facilitate interactions with the host and directly contribute to the beneficial nutritional, physiological, microbiological, and immunological effects in the host...
July 21, 2018: Applied Microbiology and Biotechnology
Zakyeh Fazilaty, Hamid Chenari, Zahra Vahdat Shariatpanahi
BACKGROUND: Trauma is associated with a profound immunological dysfunction. This predisposes patients to infections and adverse outcomes. ß-glucan has been implicated in the initiation of anti-microbial immune response. The present study aimed to evaluate the effects of an enteral diet containing ß-glucan on serum levels of IL-12 and highly-sensitive C-reactive protein (hs-CRP), occurrence of infection, and clinical outcomes in critically ill multiple-trauma patients. METHODS: Forty multiple trauma patients requiring enteral nutrition for at least 10 days were randomly assigned to the intervention group (n=20) or the placebo group (n=20)...
July 2018: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
Brian E Crucian, Alexander Choukèr, Richard J Simpson, Satish Mehta, Gailen Marshall, Scott M Smith, Sara R Zwart, Martina Heer, Sergey Ponomarev, Alexandra Whitmire, Jean P Frippiat, Grace L Douglas, Hernan Lorenzi, Judith-Irina Buchheim, George Makedonas, Geoffrey S Ginsburg, C Mark Ott, Duane L Pierson, Stephanie S Krieger, Natalie Baecker, Clarence Sams
Recent studies have established that dysregulation of the human immune system and the reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight. It appears certain aspects of adaptive immunity are dysregulated during flight, yet some aspects of innate immunity are heightened. Interaction between adaptive and innate immunity also seems to be altered. Some crews experience persistent hypersensitivity reactions during flight. This phenomenon may, in synergy with extended duration and galactic radiation exposure, increase specific crew clinical risks during deep space exploration missions...
2018: Frontiers in Immunology
Camila Cordero R, Francisca Prado S, Paulina Bravo J
Cow's milk protein allergy (CMPA) is a common disease with a prevalence of 2-7%, increasingly so. It is characterized by an allergic reaction to one or more cow's milk proteins. There are not pathog nomonic clinical symptoms, and these will depend on the type of immune reaction involved. A good diagnostic approach avoids under and over diagnosis and, therefore, under and over treatment. The CMPA treatment is the elimination of cow's milk protein from the diet. A restricted diet in a child does not require it or who has developed tolerance can alter growth, quality of life, including unne cessary costs...
June 2018: Revista Chilena de Pediatría
Fatemeh Behnia, Megan Zare, Saeed Elojeimy
Spontaneous complete and partial regression of metastatic melanoma is poorly understood, and is a rare phenomenon with less than 80 cases reported since 1866. Several correlations have been noted such as systemic or local infections, operative trauma, hormonal influences, nutrition and immunologic factors. We present FDG PET and CT findings in a patient with multiple pulmonary metastases of melanoma, one of which underwent regression following biopsy. We suggest immune system modulation, triggered by biopsy, could have played a role, although the precise mechanism remains unknown...
June 2018: Radiology Case Reports
Laurien H Ulfman, Jeanette H W Leusen, Huub F J Savelkoul, John O Warner, R J Joost van Neerven
This review aims to provide an in depth overview of the current knowledge of the effects of bovine immunoglobulins on the human immune system. The stability and functional effects of orally ingested bovine immunoglobulins in milk products are described and potential mechanisms of action are discussed. Orally ingested bovine IgG (bovine IgG) can be recovered from feces, ranging from very low levels up to 50% of the ingested IgG that has passed through the gastrointestinal tract. In infants the recovered levels are higher than in adults most likely due to differences in stomach and intestinal conditions such as pH...
2018: Frontiers in Nutrition
Chiara Porta, Arianna Marino, Francesca Maria Consonni, Augusto Bleve, Silvia Mola, Mariangela Storto, Elena Riboldi, Antonio Sica
New evidences indicate that the metabolic instruction of immunity (immune metabolism) results from the integration of cell metabolism and whole body metabolism, that are both influenced by nutrition, microbioma metabolites and disease-driven metabolism (e.g. cancer metabolism). Cancer metabolism influences the immunological homeostasis and promotes immune alterations that support disease progression, hence influencing the clinical outcome. Cancer cells display increased glucose uptake and fermentation of glucose to lactate, even in the presence of completely functioning mitochondria...
July 2, 2018: Carcinogenesis
Dalal Alkazemi, Munirah Albeajan, Stan Kubow
Objective: Early feeding and infant exposures have been suggested as potential risk factors for immunoglobulin E- (IgE-) mediated food allergy (FA). We aimed to evaluate the association between IgE-mediated FA in children and early exposures including the child's nutritional status, breastfeeding and its duration, the age at which the solid food was first introduced, antibiotic exposure during the first year of life, and the child's vitamin D status during infancy. Design: A case-control study...
2018: International Journal of Pediatrics
Andres Cardenas, Ellen Smit, Barrett M Welch, Jeff Bethel, Molly L Kile
BACKGROUND: Arsenic alters immunological parameters including antibody formation and antigen-driven T-cell proliferation. OBJECTIVE: We evaluated the cross-sectional relationship between urinary arsenic and the seroprevalence of hepatitis B (HBV) infection in the United States using data from six pooled cycles of the National Health and Nutrition Examination Survey (2003-2014, N = 12,447). METHODS: Using serological data, participants were classified as susceptible, immune due to vaccination, or immune due to past natural infection...
June 28, 2018: Environmental Research
Atsuko Imai, Eka Fujimoto, Kazuto Sato
Maternal health and nutritional status influence offspring health and the diseases that may develop in them. The effects of maternal inflammation on offspring from the perspective of the inflammatory response and immune changes are not fully understood. We hypothesized that maternal inflammation modulates immune and metabolic functions, affecting the pathophysiology of inflammatory diseases in offspring. This study investigated whether maternal inflammation affects the onset of collagen-induced arthritis (CIA), a murine model of human rheumatoid arthritis...
June 27, 2018: Inflammation
Ipsa Mohapatra, Adrija Roy
INTRODUCTION: Breast milk provides nutritional, immunological, behavioral, and economic benefits and helps to build mother-infant bonding. Antenatal mothers need to be sufficiently aware about the benefits of breastfeeding. OBJECTIVES: The aim of this study is to assess the awareness and perception of breastfeeding among antenatal mothers and to find out any association between sociodemographic factors and breastfeeding awareness. METHODOLOGY: A cross-sectional study was conducted among 250 antenatal women residing in the urban slums of field-practice area of urban health and training center; using a predesigned, pretested, semi-structured interview schedule...
2018: Journal of Education and Health Promotion
Jose U Scher
The microbiome is a known and established immunomodulator of many inflammatory disorders, including psoriasis and psoriatic arthritis. Microbes co-evolved with their human hosts and provide them with nutritional, metabolic, and immunologic support. An accumulating body of evidence has revealed that psoriatic diseases are characterized by a state of intestinal dysbiosis, which has been linked to a decrease in beneficial commensals and fatty acids. This has been shown in both animal models and human samples, and multiple studies have addressed the physiological and potentially pathogenic role of intestinal and cutaneous microbes in human health and disease...
June 2018: Journal of Rheumatology. Supplement
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