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https://www.readbyqxmd.com/read/30316069/brain-mri-findings-in-children-and-adolescents-with-fabry-disease
#1
C Marchesoni, E Cisneros, P Pfister, P Yáñez, C Rollan, C Romero, I Kisinovsky, L Rattagan, L León Cejas, A Pardal, G Sevlever, R Reisin
OBJECTIVE: To evaluate the presence of white matter and hemorrhagic lesions in brain MRI of children and adolescents with Fabry disease (FD). METHODS: Brain MRI studies in 44 consecutive children and teenagers (20 boys, mean age 14.6 years, range 7-21 years) were evaluated using classic sequences as well as, GRE-weighted images, for white matter lesions (WML) and chronic microbleed detection. All patients lacked history of stroke or TIA. Brain MRI findings in 46 consecutive children and adolescents without FD, referred for the evaluation of headaches (36 females, mean age 14...
October 5, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30306064/ct-and-mri-of-adrenal-gland-pathologies
#2
REVIEW
Fuqin Wang, Junwei Liu, Ruoxi Zhang, Yonghua Bai, Cailin Li, Bangguo Li, Heng Liu, Tijiang Zhang
Besides ultrasound and nuclear medicine techniques, computed tomography (CT) and magnetic resonance imaging (MRI) are commonly used to examine adrenal lesions in both symptomatic and asymptomatic patients. Some adrenal lesions have characteristic radiological features. If an adrenal nodule is discovered incidentally, determining whether the lesion is benign or malignant is of great importance. According to their biological behavior, lesions can be divided into benign (mainly: adenoma, hyperplasia, pheochromocytoma, cyst, hemorrhage, cystic lymphangioma, myelolipoma, hemangioma, ganglioneuroma, teratoma) and malignant (mainly: metastases, adrenal cortical carcinoma, neuroblastoma, lymphoma) conditions...
September 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/30296973/imaging-detected-tenosynovitis-of-metacarpophalangeal-and-wrist-joints-an-increasingly-recognised-characteristic-of-rheumatoid-arthritis
#3
REVIEW
Ellis Niemantsverdriet, Annette H M van der Helm-van Mil
Tenosynovitis is traditionally recognised at physical examination in patients with inflammatory rheumatic diseases, such as, e.g. psoriatic arthritis and (longstanding) rheumatoid arthritis (RA). The increasing use of sensitive imaging techniques (ultrasound, magnetic resonance imaging (MRI)) has recently revealed that subclinical tenosynovitis is prevalent in early RA and in patients in different phases of RA development (asymptomatic state, arthralgia, early arthritis). In this review, the recent findings on MRI-detected tenosynovitis and associations with RA development are highlighted, and an overview of the most reported inflamed tendon locations within the hand and wrist of patients in different disease phases is provided...
September 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/30294369/mri-in-idiopathic-stable-slipped-capital-femoral-epiphysis-evaluation-of-contralateral-pre-slip
#4
J Balch Samora, B Adler, S Druhan, S A Brown, J Erickson, W P Samora, K E Klingele
Purpose: Early diagnosis and treatment of slipped capital femoral epiphysis (SCFE) is important to prevent slip progression and avoid complications. We sought to determine if MRI findings in patients with unilateral SCFE could indicate 'pre-slip' or predict future SCFE in the contralateral hip. Methods: A prospective study evaluated patients with unilateral SCFE over a two-year period. MRI of the asymptomatic hip was performed within the perioperative period. Patients were followed with radiographs until a contralateral slip occurred or until physeal closure...
October 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/30291567/white-matter-damage-neuroinflammation-and-neuronal-integrity-in-hand
#5
Aljoharah Alakkas, Ronald J Ellis, Caitlin Wei-Ming Watson, Anya Umlauf, Robert K Heaton, Scott Letendre, Ann Collier, Christina Marra, David B Clifford, Benjamin Gelman, Ned Sacktor, Susan Morgello, David Simpson, J Allen McCutchan, Asha Kallianpur, Sara Gianella, Thomas Marcotte, Igor Grant, Christine Fennema-Notestine
HIV-associated neurocognitive disorders (HANDs) persist even with virologic suppression on combination antiretroviral therapy (cART), and the underlying pathophysiological mechanisms are not well understood. We performed structural magnetic resonance imaging and MR spectroscopy (MRS) in HIV+ individuals without major neurocognitive comorbidities. Study participants were classified as neurocognitively unimpaired (NU), asymptomatic (ANI), mild neurocognitive disorder (MND), or HIV-associated dementia (HAD). Using structural MRI, we measured volumes of cortical and subcortical gray matter and total and abnormal white matter (aWM)...
October 5, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/30279921/a-case-of-acute-heart-failure-due-to-myocardial-infiltration-of-mycosis-fungoides
#6
Tokiko Tabata, Kunihiko Kiuchi, Yuichi Nagamatsu, Yuto Shinkura, Kenzou Uzu, Jun-Ichi Ooka, Shinsuke Shimoyama, Tatsuya Nishii, Shumpei Mori, Ken-Ichi Hirata, Mariko Tsujimoto, Shoko Tajima, Eiji Nakano, Chikako Nishigori, Yuki Yamamoto, Shigeo Hara
Mycosis fungoides (MF) has been reported to be the most common cutaneous lymphoma with a good prognosis and myocardial infiltration is clinically rare. We hereby report a case of rapidly progressing acute heart failure due to myocardial infiltration by MF. Perfusion cardiac magnetic resonance imaging (MRI) demonstrated a massive perfusion defect in the left ventricle (LV) where multiple nodular enhancement areas by delayed enhancement MRI could be documented in the postero-lateral wall of the LV, which resulted in a deterioration of the LV function and mitral regurgitation...
September 2018: Journal of Cardiology Cases
https://www.readbyqxmd.com/read/30269265/prevalence-and-reproductive-manifestations-of-macroprolactinemia
#7
Amanpreet Kaur Kalsi, Ashutosh Halder, Manish Jain, P K Chaturvedi, J B Sharma
PURPOSE: Macroprolactinemia is characterized by predominance of macroprolactin molecules in circulation and generally has extra-pituitary origin. Macroprolactin is viewed as biologically inactive, therefore asymptomatic, and thus may not require any treatment or prolonged follow-up. In addition, data on prevalence of macroprolactinemia and its clinical manifestation are also rare. Therefore, the present study was aimed to find out prevalence of macroprolactinemia and its association, if any, with reproductive manifestations...
September 29, 2018: Endocrine
https://www.readbyqxmd.com/read/30258760/clinico-radiographic-discordance-an-evidence-based-commentary-on-the-management-of-degenerative-cervical-spinal-cord-compression-in-the-absence-of-symptoms-or-with-only-mild-symptoms-of-myelopathy
#8
REVIEW
Christopher D Witiw, Francois Mathieu, Aria Nouri, Michael G Fehlings
Study Design: Narrative review with commentary. Objectives: The growing use of magnetic resonance imaging (MRI) often leaves clinicians faced with scenarios where imaging findings are inconsistent with the clinical picture. This is particularly relevant for degenerative cervical spinal cord compression (CSCC). In this article, we provide a focused narrative literature review to address whether (1) surgery should be offered to asymptomatic patients with CSCC and (2) should MRI spinal cord signal changes influence clinical decisions for a patient with mild myelopathy from CSCC? Methods: Illustrative cases are presented with expert commentary which is supplemented by a focused literature review...
August 2018: Global Spine Journal
https://www.readbyqxmd.com/read/30258334/mri-findings-at-the-bone-component-interface-in-symptomatic-unicompartmental-knee-arthroplasty-and-the-relationship-to-radiographic-findings
#9
Laura Jill Kleeblad, Hendrik A Zuiderbaan, Alissa J Burge, Mark J Amirtharaj, Hollis G Potter, Andrew D Pearle
Background: The most common modes of failure of cemented unicompartmental knee arthroplasty (UKA) designs are aseptic loosening and unexplained pain at short- to mid-term follow-up, which is likely linked to early fixation failure. Determining these modes of failure remains challenging; conventional radiographs are limited for use in assessing radiolucent lines, with only fair sensitivity and specificity for aseptic loosening. Questions/Purposes: We sought to characterize the bone-component interface of patients with symptomatic cemented medial unicompartmental knee arthroplasty (UKA) using magnetic resonance imaging (MRI) and to determine the relationship between MRI and conventional radiographic findings...
October 2018: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/30254950/magnetic-resonance-imaging-in-the-evaluation-of-cesarean-scar-defect
#10
Wu Shun Felix Wong, Wing Tak Fung
The incidence of Cesarean scar defect (CSD) would increase with the increasing trends of cesarean section delivery. The actual incidence of this condition is unknown, but it had been estimated by hysteroscopy, sonohysterography, or transvaginal ultrasound to be around 50% of patients with cesarean section. CSD is often asymptomatic, but it may produce common symptoms such as abnormal uterine bleeding, infertility, and pelvic pain. Adverse pregnancy outcomes with scar ectopic pregnancy, uterine rupture had been reported...
July 2018: Gynecology and minimally invasive therapy
https://www.readbyqxmd.com/read/30233756/asymptomatic-endophthalmitis-following-strabismus-correction-in-a-pediatric-patient
#11
Cory M Pfeifer, Rana M Yazdani
Endophthalmitis is most commonly seen in adults shortly after cataract surgery. It is rare in the pediatric population. Presented here is a case of endophthalmitis following strabismus repair in a 9-month-old patient with Trisomy 21. Leukocoria was observed 15 days after surgery, but the child did not exhibit symptoms of infection, and the ordering clinician requested an MRI of the brain and orbits to assess the possibility of retinoblastoma. This case highlights the importance of MRI in the evaluation of leukocoria and displays typical MRI findings of this infrequently-encountered condition in the pediatric population...
December 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/30230998/case-262
#12
Andrew H Schapiro, Mantosh S Rattan, Ryan A Moore, Jonathan R Dillman
History A 17-year-old white male adolescent was re-evaluated for a withheld cardiac condition initially detected during prenatal imaging at an outside institution. He had previously experienced intermittent episodes of shortness of breath, chest pain, and palpitations with exertion, but more recently he had been asymptomatic. He had no other comorbidities and no family history of congenital heart disease, cardiomyopathy, arrhythmia, or sudden cardiac death. At physical examination, the patient had a grade II/IV rumbling systolic murmur best heard at the left upper sternal border...
October 2018: Radiology
https://www.readbyqxmd.com/read/30230086/next-generation-sequencing-of-the-cellular-and-liquid-fraction-of-pancreatic-cyst-fluid-supports-discrimination-of-ipmn-from-pseudocysts-and-reveals-cases-with-multiple-mutated-driver-clones-first-findings-from-the-prospective-zysteus-biomarker-study
#13
Anna-Lena Volckmar, Volker Endris, Matthias M Gaida, Jonas Leichsenring, Fabian Stögbauer, Michael Allgäuer, Moritz von Winterfeld, Roland Penzel, Martina Kirchner, Regine Brandt, Olaf Neumann, Holger Sültmann, Peter Schirmacher, Jochen Rudi, Daniel Schmitz, Albrecht Stenzinger
Half of all pancreatic cysts are neoplastic, mainly comprising intraductal papillary mucinous neoplasms (IPMN), which can progress to cancer. Current Fukuoka guidelines have limited sensitivity and specificity predicting progression of asymptomatic pancreatic cysts. We present first results of the prospective ZYSTEUS biomarker study investigating i) whether detection of driver mutations in IPMN by liquid biopsy is technically feasible, ii) which compartment of IPMN is most suitable for analysis, and iii) implications for clinical diagnostics...
September 19, 2018: Genes, Chromosomes & Cancer
https://www.readbyqxmd.com/read/30222696/neuroimaging-profiles-and-neurodevelopmental-outcome-in-infants-with-congenital-cytomegalovirus-infection
#14
Antonietta Giannattasio, Dario Bruzzese, Pasquale Di Costanzo, Eleonora Capone, Antonia Romano, Alessandra D'Amico, Carmela Bravaccio, Claudia Grande, Letizia Capasso, Francesco Raimondi
BACKGROUND: The accurate stratification of infants with congenital cytomegalovirus (CMV) infection at risk for more severe outcome may help in the management of patients. Aim of this study was to investigate the ability of a comprehensive neuroimaging investigation in predicting the long-term neurodevelopmental outcome in patients with congenital CMV. We analyzed the prognostic accuracy of a traditional score and a recently proposed scale applied to head ultrasound (HUS), computed tomography (CT) and magnetic resonance imaging (MRI)...
October 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/30214490/magnetic-resonance-imaging-scans-are-not-a-reliable-tool-for-predicting-symptomatic-acromioclavicular-arthritis
#15
Bijayendra Singh, Abhinav Gulihar, Praveen Bilagi, Arpit Goyal, Pallavi Goyal, Rajesh Bawale, Dilip Pillai
Background: We investigated whether magnetic resonance imaging (MRI) scans can accurately diagnose arthritis of the acromioclavicular joint (ACJ) because it has recently been suggested that bone marrow oedema on MRI scans is a predictive sign of symptomatic ACJ arthritis. Methods: The MRI scans of 43 patients (50 shoulders) who underwent ACJ excision for clinically symptomatic ACJ arthritis were compared to a control group of 43 age- and sex-matched patients (48 shoulders) who underwent an MRI scan for investigation of shoulder pain but did not have clinical symptoms or signs of ACJ arthritis...
October 2018: Shoulder & Elbow
https://www.readbyqxmd.com/read/30212939/anomalous-course-and-stenosing-tenosynovitis-of-the-extensor-pollicis-longus-tendon-at-the-radial-styloid-process-a-case-report
#16
Young-Keun Lee, Malrey Lee
RATIONALE: Anomalous course and tenosynovitis of extensor pollicis longus (EPL) tendon is a rare condition that presents clinical symptoms very similar to de Quervain's disease. Herein we report a case of anomalous course and tenosynovitis of the extensor pollicis longus (EPL) tendon associated with symptoms of de Quervain's disease. PATIENT CONCERNS: A 44-year-old right-handed man visited the clinic because of radial pain associated with the left wrist, which was aggravated during the previous 10 days...
September 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30211685/incidental-bladder-cancers-found-on-multiparametric-mri-of-the-prostate-gland-a-single-center-experience
#17
Kareem N Rayn, Graham R Hale, Jonathan B Bloom, Samuel A Gold, Filipe L F Carvalho, Sherif Mehralivand, Marcin Czarniecki, Bradford J Wood, Maria J Merino, Peter Choyke, Barış Türkbey, Peter A Pinto, Piyush K Agarwal
PURPOSE: In the era of multiparametric magnetic resonance imaging (mpMRI) of the prostate gland, incidental findings are occasionally discovered on imaging. We aimed to report our experience of detecting incidental bladder cancers on mpMRI of the prostate in asymptomatic patients without irritative voiding symptoms or microscopic or gross hematuria. METHODS: A retrospective review was performed on a prospectively maintained database of all men who underwent prostate mpMRI at our institution from 2012 to 2018...
September 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/30197821/the-use-of-imaging-in-management-of-patients-with-low-back-pain
#18
REVIEW
Dinesh Rao, Gaelyn Scuderi, Chris Scuderi, Reetu Grewal, Sukhwinder Js Sandhu
Lower back pain (LBP) is one of the most common chief complaints encountered in primary care. Advanced imaging studies, including computerized tomography (CT) and magnetic resonance imaging (MRI), are frequently ordered in the setting of LBP. Structural abnormalities are commonly identified by CT and MRI in patients complaining of low back pain, however, these findings are also found in asymptomatic patients. In the past decade, multiple guidelines have been published to help providers identify patients in whom the use of advanced imaging is appropriate...
2018: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/30189404/adenoid-cystic-carcinoma-of-the-breast-experience-at-a-tertiary-care-centre-of-northern-india
#19
Namita Bhutani, Pradeep Kajal, Sham Singla
INTRODUCTION: Adenoid cystic carcinoma of the breast (breast-ACC) is a rare tumor with a favorable prognosis, despite its triple-negative status and special type of basal-like tumor for which scant population-based descriptive data exist. We sought to provide new population-based information on breast-ACC in India. Due to the paucity of the number of cases, the natural history of the disease is not fully understood. This study was undertaken to examine the clinico-pathological characteristics of the disease and to evaluate the outcome of surgical intervention in a tertiary referral care centre...
August 31, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/30186228/presence-of-middle-cerebellar-peduncle-sign-in-fmr1-premutation-carriers-without-tremor-and-ataxia
#20
Jessica L Famula, Forrest McKenzie, Yingratana A McLennan, James Grigsby, Flora Tassone, David Hessl, Susan M Rivera, Veronica Martinez-Cerdeno, Randi J Hagerman
Here we report five cases of male FMR1 premutation carriers who present without clinical symptoms of the fragile X-associated tremor/ataxia syndrome (FXTAS), but who on MRI demonstrate white matter hyperintensities in the middle cerebellar peduncles (MCP sign) and other brain regions, a rare finding. MCP sign is the major radiological feature of FXTAS; it is therefore remarkable to identify five cases in which this MRI finding is present in the absence of tremor and ataxia, the major clinical features of FXTAS...
2018: Frontiers in Neurology
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