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Solid phase extraction

Nicole Alessandra Munz, Qiuguo Fu, Christian Stamm, Juliane Hollender
Internal concentrations link external exposure to the potential effect, as they reflect what the organisms actually take up and experience physiologically. In this study, we investigated whether frequently detected risk-driving substances in water were found in the exposed organisms and if they are classified the same based on the whole body internal concentrations. Field gammarids were collected upstream and downstream of ten wastewater treatment plants in mixed land use catchments. The sampling was conducted in autumn and winter, during low flow conditions when diffuse agricultural input was reduced...
August 17, 2018: Environmental Science & Technology
Mengbi Wei, Xianhai Yang, Peter Watson, Feifei Yang, Huihui Liu
In recent years, extensive attention has been paid to the passive sampling technology of diffusive gradients in thin films (DGT) due to its growing application in the measurement of a widening variety of compounds. Within any DGT device, the binding phase is a key component, and seeking novel binding phases is an issue worth studying. Cyclodextrin polymer, as a green and eco-friendly material, may be a good choice for measuring organic chemicals. In this study, a novel DGT sampler with cyclodextrin polymer membrane (CDPM) as the binding phase was developed for measuring the concentrations of triclosan, triclocarban and methyl triclosan...
August 11, 2018: Science of the Total Environment
Joachim Kuhn, Tatjana Gripp, Tobias Flieder, Andreas Hammerschmidt, Doris Hendig, Isabel Faust, Cornelius Knabbe, Ingvild Birschmann
BACKGROUND: Measurement of direct oral anticoagulants (DOACs) concentration in patient blood is essential in special clinical circumstances. METHODS: We developed a fast, selective and sensitive method for simultaneous measurement of DOACs in human plasma consisting of an automated online solid-phase extraction method coupled with ultra-performance liquid chromatography electrospray ionization-tandem mass spectrometry (online SPE-UPLC-MS/MS). RESULTS: The calibration curves of all DOACs were linear over the working range (apixaban: 0...
August 13, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
Ewa Bartosińska, Julia Jacyna, Agnieszka Borsuk-De Moor, Michał Kaliszan, Karolina Kondej, Jerzy Jankau, Alicja Renkielska, Wiesław Janusz Kruszewski, Michał Jan Markuszewski, Danuta Siluk
Tocopherols and tocotrienols have been extensively studied due to their anticancer potential, especially against breast cancer. Therefore, the aim of this study was to quantitatively determine tocochromanols in human breast adipose tissue with the use of HPLC-FLD. The sample preparation procedure included homogenization and solvent extraction with isopropanol/ethanol/0.1% formic acid mixture prior to solid phase extraction (SPE). After implementation of central composite design (CCD), satisfactory separation of all eight target compounds was achieved within 10...
August 16, 2018: Biomedical Chromatography: BMC
Kaylee R Mastrianni, William E Kemnitzer, Kevin W P Miller
Catecholamines are integral neurotransmitters in the central and peripheral nervous system. Clinically, catecholamine levels are determined to help diagnose disease and measure corresponding therapeutic effectiveness. However, manual extraction of catecholamines and their metabolites may be labor-intensive and user-variable and require a variety of peripheral laboratory devices, especially at low sample concentrations. Here, we propose a novel solid-phase extraction (SPE) method using patented dispersive pipette extraction (DPX) tip technology...
August 15, 2018: SLAS Technology
Marianne A Mahrouse
Therapeutic drug monitoring of angiotensin converting enzyme inhibitors (ACEI) has a great impact in blood pressure control in patient with heart failure, hepatic and renal impairment. To provide an efficient tool for drug assessment in plasma, UPLC-MS/MS method was developed for simultaneous determination of benazepril hydrochloride (BNZ), fosinopril sodium (FOS), captopril (CAP) and hydrochlorothiazide (HCT) in human plasma samples. Solid phase extraction was applied for sample preparation using OASIS® hydrophilic-lipophilic balanced reversed phase sorbents cartridges...
August 14, 2018: Biomedical Chromatography: BMC
Ondra Sracek, Bohdan Kříbek, Martin Mihaljevič, Vojtěch Ettler, Aleš Vaněk, Vít Penížek, Jan Filip, František Veselovský, Imasiku Nyambe
The impact of a natural wetland ("dambo" in Zambia) on neutral mine drainage at Luanshya in the Zambian Copperbelt has been investigated during an intermediate discharge period (July) using a multi-method characterization of solid phase samples, sequential extraction analysis, X-ray diffraction, Mössbauer spectroscopy, and scanning electron microscopy combined with water analyses, isotopic analyses, and geochemical modeling. In the wetland, the principal identified solid phases in sediments were carbonates, gypsum, and ferric oxyhydroxides...
August 14, 2018: Environmental Science and Pollution Research International
Bernabé L Rivas, Bruno F Urbano, Julio Sánchez
The polymeric materials have presented a great development in adsorption processes for the treatment of polluted waters. The aim of the current review is to present the recent developments in this field of study by examining research of systems like functional water-soluble polymers and water-soluble polymer-metal complexes coupled to ultrafiltration membranes for decontamination processes in liquid-liquid phase. Noticing that a water-soluble polymer can be turned into insoluble compounds by setting a crosslinking point, connecting the polymer chains leading to polymer resins suitable for solid-liquid extraction processes...
2018: Frontiers in Chemistry
Syed Fariq Fathullah Syed Yaacob, Muhammad Afzal Kamboh, Wan Aini Wan Ibrahim, Sharifah Mohamad
A magnetic solid-phase extraction (MSPE) procedure on the newly synthesized magnetic β-cyclodextrin functionalized with toluene diisocyanate (TDI) as a linker and further modified with bio-polymeric spores of sporopollenin (MSp-TDI-βCD), was developed for the extraction of nonsteroidal anti-inflammatory drugs (NSAIDs), namely, indoprofen (INP), ketoprofen (KTP), ibuprofen (IBP) and fenoprofen (FNP) from water samples prior to their HPLC-DAD determination. The newly synthesized MSp-TDI-βCD was comprehensibly characterized using FT-IR, XRD, SEM-EDX, BET and VSM analyses...
July 2018: Royal Society Open Science
Liping Sun, Yuxin Ma, Hongying Wang, Tao Zhu
After being coupled, florisil was modified with four kinds of groups and they were applied to the determination of rutin in orange peel sample by a pipette-tip solid-phase extraction method. The materials were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis and specific surface area by Brunauer Emmett Teller N2 adsorption desorption analysis. Florisil and five modified materials were tested by static adsorption, and the result showed that the material with 4-bromoanisole had the best adsorption amount for rutin...
August 14, 2018: Journal of Separation Science
Cathy Muste, Kevin G Owens
Current literature shows a gap for methods which can identify yeast sub-species (strains or serovars) in samples where there are no viable cells remaining. Presented here is a technique for the analysis of yeast supernatant, including solid phase extraction, data-dependent acquisition liquid chromatography/mass spectrometry (LC-MS), and two chemometric methods to identify and classify yeast strains. Five strains of Saccharomyces cerevisiae were successfully identified in various stages of growth. In addition, peptide/protein identification was performed, without the need for additional data acquisition...
August 13, 2018: Journal of the American Society for Mass Spectrometry
Paris Ning, Ronald Soong, Wolfgang Bermel, Daniel Lane, Myrna J Simpson, André J Simpson
Many natural and environmental samples contain combinations of liquids, gels, and solids, yet quantification in the intact state and across multiple phases is highly challenging. Comprehensive multiphase nuclear magnetic resonance (CMP-NMR) combines all the capabilities of high-resolution magic angle spinning (HR-MAS), with the addition of full solids power handling, permitting all phases (i.e., mixtures of liquids, gels, and solids) to be studied and differentiated in intact samples without pre-treatment or extraction...
August 13, 2018: Analytical and Bioanalytical Chemistry
Samson Baranzan Wayah, Koshy Philip
BACKGROUND: Emergence of antibiotic resistance and growing consumer trend towards foods containing biopreservatives stimulated the search for alternative antimicrobials. This research is aimed at characterizing, investigating the mechanism of action, scale up optimization and evaluating the biopreservative potential of a bacteriocin from Lactobacillus fermentum. RESULTS: Fermencin SA715 is a novel, broad-spectrum, non-pore-forming and cell wall-associated bacteriocin isolated from L...
August 13, 2018: Microbial Cell Factories
Juan José Villaverde, Beatriz Sevilla-Morán, Carmen López-Goti, José Luis Alonso-Prados, Pilar Sandín-España
Assessment of two buffered QuEChERS (quick, easy, cheap, effective, rugged, and safe) versions (i.e., citrate and acetate) modified by including methanol to recover the residues of three cyclohexanedione oxime (CHD) herbicides and three of their byproducts from agricultural soil was performed. In this context, a full second-order face-centered factorial experimental design was developed to quantify the influences of the main five variables (i.e., extraction time, water content, soil weight, and extraction solvent volume and composition) on the target compound recoveries...
August 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Bithika Saha, Rocco Longo, Peter Torley, Anthony Saliba, Leigh Schmidtke
The important sampling parameters of a headspace solid-phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS) procedure such as the extraction temperature, extraction time, and sample volume were optimized to quantify 23 important impact odorants in reduced alcohol red and white wines. A three-factor design of Box-Behnken experiments was used to determine the optimized sampling conditions for each analyte, and a global optimized condition at every ethanol concentration of interest determined using a desirability function that accounts for a low signal response for compounds...
August 10, 2018: Foods (Basel, Switzerland)
Maristela B R Cerqueira, Karina L Soares, Sergiane S Caldas, Ednei G Primel
A method based on matrix-solid phase dispersion (MSPD), focused on the principles of green analytical chemistry, aimed at the use of alternative solid supports and less toxic solvents, was developed for the simultaneous determination of 19 pharmaceuticals, 4 personal care products (PPCPs) and 4 degradation products in sewage sludge samples. Higher recoveries were achieved when 2 g sample was macerated for 5 min in a glass mortar, transferred to a centrifuge tube, and 1 min vortex agitation with 5 mL methanol...
July 30, 2018: Chemosphere
Min Wang, Jiajing Sheng, Qian Wu, Yingchang Zou, Yanjie Hu, Kejing Ying, Hao Wan, Ping Wang
Lung cancer (LC) is a leading cause of cancer-related morbidity and mortality globally, and exhaled breath test has been considered as a fast, convenient and non-invasive way to diagnose LC in early stage. Volatile organic compounds (VOCs), as markers of LC in exhaled breath, has been widely investigated for cancer diagnosis. However, few study reports about the interference of benign pulmonary diseases (BPD) for selecting VOCs markers of LC. During this study, 207 samples were analyzed by thermal desorption instrument/gas chromatography/mass spectrometry (TD-GCMS) to detect C6∼C30 VOCs, and all samples were divided into four groups: LC group, BPD group, lung disease (LD) group (including LC group and BPD group) and health group...
August 13, 2018: Journal of Breath Research
Hitoshi Mizuguchi, Ryota Ishida, Yasushi Kouno, Tadahiko Tachibana, Tomomi Honda, Tatsuro Kijima, Yuhei Yamamoto, Toshio Takayanagi
A new method for the rapid enrichment and highly sensitive determination of nickel ion has been developed by using a nanofiber-composite membrane filter, which was fabricated by stacking a nanofibrous material made of nylon 6 over a water-permeable membrane filter. The noncharged nickel-α-furil dioxime complex was adsorbed on a nanofibrous layer of the membrane filter under significantly higher flow rates than those used for conventional solid-phase extraction techniques. Highly sensitive determinations with detection limits at sub-parts per billion levels were achieved by enrichment from 50 mL of the complex solution, and the enrichment was completed within 3 min...
2018: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
Yang Xu, Qing Wang, Zhihui Yin, Xiaoyan Gao
The traditional studies on metabolism in liver microsomes were carried out in off-line form. In this paper, a rapid and convenient method for the study of metabolism of substrates in liver microsomes was established by means of ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS): on-line incubation and real-time detection of substrates in liver microsomes. The liver microsomal incubation system was placed in a sample chamber at 37 °C. On-line solid phase extraction (SPE) column was used for on-line sample treatment, its function was to enrich the drug prototype and its metabolites with weak polarity, and elute the phosphate in the samples...
August 2, 2018: Journal of Chromatography. A
Jing Wang, Manshun Liu, Liang Zhang, Tianshu Zhang, Tianli Yue, Zhonghong Li, Na Hu, Yourui Suo, Jianlong Wang
Here, a solid/liquid phase extraction mode was used for the preconcentration of Pb(II) in water and food samples through a biomass reinforced graphene oxide (BGO) membrane. Taking advantage of the two modes, the synergistic effect of BGO membrane (solid extraction) and organic solvent (liquid extraction) enhances the extraction efficiency toward target ion. In detail, the effect of composition parameters in BGO membrane and experiment conditions such as pH, eluent types, elution time and sample volume were optimized, as well as shows no obvious interference toward different competing ions...
December 15, 2018: Food Chemistry
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