Sarah L Tansley, Fionnuala McMorrow, Caroline V Cotton, Huzaifa Adamali, Shaney L Barratt, Zoe E Betteridge, Janire Perurena-Prieto, Michael A Gibbons, Raman Kular, Aravinthan Loganathan, Janine A Lamb, Hui Lu, Robert P New, Diane Pratt, Pilar Rivera-Ortega, Ross Sayers, Matthew Steward, Lachlan Stranks, Edward Vital, Lisa G Spencer, Neil J McHugh, Robert G Cooper
BACKGROUND: Autoantibodies are a hallmark feature of Connective Tissue Diseases (CTD). Their presence in patients with idiopathic interstitial lung disease (ILD) may suggest covert CTD. We aimed to determine the prevalence of CTD autoantibodies in patients diagnosed with idiopathic ILD. METHODS: 499 patient sera were analysed: 251 idiopathic pulmonary fibrosis (IPF), 206 idiopathic non-specific interstitial pneumonia (iNSIP) and 42 cryptogenic organising pneumonia (COP)...
April 2, 2024: Clinical Immunology: the Official Journal of the Clinical Immunology Society