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Clinical nutrition

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https://www.readbyqxmd.com/read/29679742/adaptive-thermogenesis-by-dietary-n-3-polyunsaturated-fatty-acids-emerging-evidence-and-mechanisms
#1
REVIEW
Rong Fan, Karsten Koehler, Soonkyu Chung
Brown/beige fat plays a crucial role in maintaining energy homeostasis through non-shivering thermogenesis in response to cold temperature and excess nutrition (adaptive thermogenesis). Although numerous molecular and genetic regulators have been identified, relatively little information is available regarding thermogenic dietary molecules. Recently, a growing body of evidence suggests that high consumption of n-3 polyunsaturated fatty acids (PUFA) or activation of GPR120, a membrane receptor of n-3 PUFA, stimulate adaptive thermogenesis...
April 18, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29679620/longitudinal-association-between-periodontitis-and-development-of-diabetes-running-title-periodontitis-and-diabetes-development
#2
Kaumudi J Joshipura, Francisco J Muñoz-Torres, Bruce A Dye, Brian G Leroux, Margarita Ramírez-Vick, Cynthia M Pérez
BACKGROUND: Clinical trials have shown very modest short-term improvements in glycemic control among participants with diabetes after periodontitis treatment. Few longitudinal studies suggest that periodontitis may be related to prediabetes/diabetes risk. METHODS: We evaluated 1,206 diabetes free participants in the San Juan Overweight Adults Longitudinal Study (SOALS) and 941 with complete 3-year follow-up data were included. The National Health and Nutrition Examination Survey (NHANES) methods were used to assess periodontitis...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29679617/retinopathy-of-prematurity-a-review-of-risk-factors-and-their-clinical-significance
#3
REVIEW
Sang Jin Kim, Alexander D Port, Ryan Swan, J Peter Campbell, R V Paul Chan, Michael F Chiang
Retinopathy of prematurity (ROP) is a retinal vasoproliferative disease that affects premature infants. Despite improvements in neonatal care and management guidelines, ROP remains a leading cause of childhood blindness worldwide. Current screening guidelines are primarily based on two risk factors: birth weight and gestational age; however, many investigators have suggested other risk factors, including maternal factors, prenatal and perinatal factors, demographics, medical interventions, comorbidities of prematurity, nutrition, and genetic factors...
April 19, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29679304/analytic-approaches-for-the-treatment-of-hyperhomocysteinemia-and-its-impact-on-vascular-disease
#4
REVIEW
Soo-Sang Kang, Robert S Rosenson
Homocysteine is an intermediary metabolite in the methionine cycle. Accumulation of homocysteine is caused either by mutation of relevant genes or by nutritional depletion of related vitamin(s). This review covers the historical background of hyperhomocysteinemia in which indispensable subjects in relation to underlying pathophysiological processes are discussed with the view of metabolism and genetics of folate and methionine cycles. This review emphasizes the unique role of homocysteine that is clearly distinct from other risk factors, particularly cholesterol in the development of vascular disease...
April 20, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29678805/mobile-health-to-maintain-continuity-of-patient-centered-care-for-chronic-kidney-disease-content-analysis-of-apps
#5
Ying-Li Lee, Yan-Yan Cui, Ming-Hsiang Tu, Yu-Chi Chen, Polun Chang
BACKGROUND: Chronic kidney disease (CKD) is a global health problem with a high economic burden, which is particularly prevalent in Taiwan. Mobile health apps have been widely used to maintain continuity of patient care for various chronic diseases. To slow the progression of CKD, continuity of care is vital for patients' self-management and cooperation with health care professionals. However, the literature provides a limited understanding of the use of mobile health apps to maintain continuity of patient-centered care for CKD...
April 20, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29678205/management-of-severe-acute-malnutrition-by-cow-milk-in-resource-constraints-settings-experience-of-the-nutritional-centre-of-the-university-clinics-of-graben
#6
Mupenzi Mumbere, F Katsuva Mbahweka, B P Furaha Nzanzu
BACKGROUND: Severe acute malnutrition is defined as a weight for height z-score < - 3 standard deviation. Since 2000, joint efforts of the World Health Organization and United Nations Children's Fund allowed to standardize the management of acute malnutrition by improving outcome and preventing complications with the introduction of therapeutic milk and ready-to-use therapeutic foods. However, in the Democratic Republic of Congo, many health facilities face therapeutic milk shortage while managing severe acute malnutrition...
April 20, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29677205/anemia-in-tuberculosis-cases-and-household-controls-from-tanzania-contribution-of-disease-coinfections-and-the-role-of-hepcidin
#7
Jerry Hella, Colin I Cercamondi, Francis Mhimbira, Mohamed Sasamalo, Nicole Stoffel, Marcel Zwahlen, Thomas Bodmer, Sebastien Gagneux, Klaus Reither, Michael B Zimmermann, Lorenz Risch, Lukas Fenner
BACKGROUND: Tuberculosis (TB) induces a systemic inflammatory state affecting iron homeostasis. Patients with TB often have additional comorbidities such as anemia which can result in poorer treat outcomes. We studied the contribution of anemia and the role of the iron regulatory hormone hepcidin among TB patients and household contacts. METHODS: We analyzed serum samples from 102 TB cases and 98 controls without TB, matched by age/sex, for hepcidin, iron, and inflammation parameters...
2018: PloS One
https://www.readbyqxmd.com/read/29676072/current-management-of-moderate-to-severe-atopic-dermatitis-a-survey-of-allergists-pediatric-allergists-and-dermatologists-in-korea
#8
Hye Yung Yum, Hyun Hee Kim, Hyun Jung Kim, Woo Kyung Kim, So Yeon Lee, Kapsok Li, Dong Hun Lee
PURPOSE: There is an unmet need for the treatment of moderate-to-severe atopic dermatitis (AD), leading to variation in management strategies. To investigate distinct features and treatment modalities according to physicians' specialties, we collected data on the current treatment approach to moderate-to-severe AD among allergists, pediatric allergists and dermatologists in Korea. METHODS: This questionnaire-based study was administered to physicians from the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI), Korean Academy of Pediatric Allergy and Respiratory Disease (KAPARD), and Korean Atopic Dermatitis Association (KADA)...
May 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29675875/effects-of-a-supportive-care-bundle-on-sleep-variables-of-preterm-infants-during-hospitalization
#9
Hsiang-Yun Lan, Luke Yang, Kao-Hsian Hsieh, Ti Yin, Yue-Cune Chang, Jen-Jiuan Liaw
Sleep is important for preterm infants' brain development, but they are frequently exposed to painful procedures in the neonatal intensive care unit (NICU) that disturb their sleep cycle and affect their growth. The purpose of this study was to examine the prolonged effects of a supportive care bundle (modulation of the infants' states, non-nutritive sucking, facilitated tucking, and oral sucrose feeding) on preterm infants' sleep variables (sleep efficiency, total sleep time, sleep latency, and frequency of wake bouts) during hospitalization...
April 20, 2018: Research in Nursing & Health
https://www.readbyqxmd.com/read/29675077/a-tale-of-treatable-infantile-neuroregression-and-diagnostic-dilemma-with-glutaric-aciduria-type-i
#10
Sangeetha Yoganathan, Mugil Varman, Samuel Philip Oommen, Maya Thomas
Nutritional deficiencies related neurological manifestations are not uncommon in infants and children. Here, we describe an infant with Vitamin B12 deficiency due to depleted maternal Vitamin B12 status presenting with progressive encephalopathy and extrapyramidal signs. Diagnosis of infantile tremor syndrome was established in our patient based on the clinical and biochemical parameters. Magnetic resonance imaging had shown frontotemporal atrophy with widened Sylvian fissures and prominent cerebrospinal fluid spaces...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29674851/gastrointestinal-obstruction-caused-by-solidification-and-coagulation-of-enteral-nutrition-pathogenetic-mechanisms-and-potential-risk-factors
#11
Grazia Leonello, Antonio Giacomo Rizzo, Viviane Di Dio, Antonio Soriano, Claudia Previti, Grazia Giulia Pantè, Claudio Mastrojeni, Sebastiano Pantè
Enteral nutrition (EN) is preferred in order to provide nutrition and reduce catabolism in critically ill patients. Recent studies suggest that the use of EN is successful and complications are rare. However, an underestimated mechanical complication of tube feedings seen in critically ill patients is the coagulation and solidification of the EN causing gastrointestinal obstruction. This report describes two clinical cases (1.23% of all cases seen at our clinic) of obstruction and perforation of the small bowel secondary to the solidification of EN...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29674134/higher-dietary-acid-load-is-associated-with-higher-likelihood-of-peripheral-arterial-disease-among-american-adults
#12
Mohsen Mazidi, Dimitri P Mikhailidis, Maciej Banach
OBJECTIVE: To explore the association between dietary acid load, potential renal acid load (PRAL) and net endogenous acid production (NEAP), and peripheral arterial disease (PAD) in a national representative sample of American adults. METHODS: The National Health and Nutrition Examination Survey (NHANES) database (for 1999-2002) was used. PAD was diagnosed by ankle brachial index assessment. Analysis of covariance was used to examine adjusted mean of different dietary acid load by PAD status; multivariable logistic regression was used to relate dietary acid load with prevalent PAD...
March 9, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29673832/effects-of-physical-training-with-the-nintendo-wii-fit-plus-%C3%A2-and-protein-supplementation-on-musculoskeletal-function-and-the-risk-of-falls-in-pre-frail-older-women-protocol-for-a-randomized-controlled-clinical-trial-the-wiiprotein-study
#13
Audrin Said Vojciechowski, Simone Biesek, Jarbas Melo Filho, Estela Iraci Rabito, Maryelle Paula do Amaral, Anna Raquel Silveira Gomes
BACKGROUND: Frailty is one of the key geriatric syndromes and is related to the loss of functional independence. However, the practice of physical training (PT) combined with protein supplementation (PS) may improve musculoskeletal function (MF). OBJECTIVE: To verify the effect of PT using 'exergames' with or without PS on MF, nutritional status, and risk of falls in pre-frail older women. METHOD: The protocol is for a randomized controlled clinical trial with a sample of pre-frail older women, divided into 5 groups: control group; PT using exergames; PS; PT using exergames combined with PS; PT using exergames combined with isoenergetic supplementation...
May 2018: Maturitas
https://www.readbyqxmd.com/read/29673830/is-telehealth-effective-in-managing-malnutrition-in-community-dwelling-older-adults-a-systematic-review-and-meta-analysis
#14
REVIEW
Wolfgang Marx, Jaimon T Kelly, Megan Crichton, Dana Craven, Jorja Collins, Hannah Mackay, Elizabeth Isenring, Skye Marshall
Telehealth offers a feasible method to provide nutrition support to malnourished older adults. This systematic review and meta-analysis aims to determine the efficacy of telehealth methods in delivering malnutrition-related interventions to community-dwelling older adults. Studies in any language were searched in five electronic databases from inception to 2nd November 2017. Quality of the evidence was assessed using the Cochrane Risk of Bias tool and the GRADE approach. Nine studies were identified, with results published across 13 included publications, which had mostly low to unclear risk of bias...
May 2018: Maturitas
https://www.readbyqxmd.com/read/29673501/association-of-sarcopenia-with-nutritional-parameters-quality-of-life-hospitalization-and-mortality-rates-of-elderly-patients-on-hemodialysis
#15
Juliana Giglio, Maria Ayako Kamimura, Fernando Lamarca, Juliana Rodrigues, Fernanda Santin, Carla Maria Avesani
OBJECTIVE: This study aimed to assess whether diminished muscle mass, diminished muscle strength, or both conditions (sarcopenia) are associated with worse nutritional status, poor quality of life (QoL), and hard outcomes, such as hospitalization and mortality, in elderly patients on maintenance hemodialysis (MHD). DESIGN AND SUBJECTS: This is a multicenter observational longitudinal study that included 170 patients on MHD (age 70 ± 7 years, 65% male) from 6 dialysis centers...
May 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29673331/prevalence-and-factors-associated-with-preterm-birth-at-kenyatta-national-hospital
#16
Peter Wagura, Aggrey Wasunna, Ahmed Laving, Dalton Wamalwa, Paul Ng'ang'a
BACKGROUND: The World Health Organization estimates the prevalence of preterm birth to be 5-18% across 184 countries of the world. Statistics from countries with reliable data show that preterm birth is on the rise. About a third of neonatal deaths are directly attributed to prematurity and this has hindered the achievement of Millennium Development Goal-4 target. Locally, few studies have looked at the prevalence of preterm delivery and factors associated with it. This study determined the prevalence of preterm birth and the factors associated with preterm delivery at Kenyatta National Hospital in Nairobi, Kenya...
April 19, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29672576/malnutrition-and-lipid-abnormalities-in-antiretroviral-na%C3%A3-ve-hiv-infected-adults-in-addis-ababa-a-cross-sectional-study
#17
Melaku Adal, Rawleigh Howe, Desta Kassa, Abraham Aseffa, Beyene Petros
BACKGROUND: Both under- and over-nutrition may occur among human immunodeficiency virus (HIV)-infected individuals and impact on the course of the acquired immune deficiency syndrome (AIDS) and its management due to the close interaction between immunity and nutrition. We investigated occurrence of undernutrition, excess weight and lipid abnormalities among antiretroviral naïve HIV-infected adults in Addis Ababa, Ethiopia. METHODS: A cross-sectional study on 594 antiretroviral therapy (ART) naïve HIV-infected adults was conducted in four hospitals in Addis Ababa from February to September 2013...
2018: PloS One
https://www.readbyqxmd.com/read/29671294/standard-of-care-controversies-and-innovations-in-the-medical-treatment-of-severe-traumatic-brain-injury-stbi
#18
Alba Scerrati, Silvia De Rosa, Lorenzo Mongardi, Michele A Cavallo, Giorgio Trapella, Pasquale De Bonis
Severe traumatic brain injury (STBI) is characterized by a primary injury which cannot be reversed and a secondary injury that can be prevented or reversed. Management of STBI patients in intensive care mainly aims at preventing the secondary injury. Treatment aims to: reducing ICP pressure (that can result in an ischemic insult); avoiding hypotension, hyperthermia, or hypoxemia; maintaining a normal electrolytes homeostasis; treating the Autonomic dysfunction syndrome, coagulopathies, Acute Kidney Injury and maintaining an adequate nutrition...
April 18, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29671062/the-impact-of-dietary-regimen-compliance-on-outcomes-for-hnscc-patients-treated-with-radiation-therapy
#19
Rafi Kabarriti, Amanda Bontempo, Maria Romano, Kevin P McGovern, Alyssa Asaro, Shankar Viswanathan, Shalom Kalnicki, Madhur K Garg
OBJECTIVE: To analyze nutritional factors and compliance with dietary recommendations for associations with overall survival (OS) and progression-free survival (PFS) in patients receiving definitive RT for laryngeal and oropharyngeal cancers. MATERIALS/METHODS: We identified 352 patients with non-metastatic laryngeal (146) and oropharyngeal (206) cancer treated with definitive RT between 2004 and 2013. Disease and patient characteristics, treatment information, sarcopenia based on muscle areas at L3 level on CT, compliance with the nutritional program, and clinical outcomes data were tabulated...
April 18, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29670613/innate-immunity-in-the-persistent-inflammation-immunosuppression-and-catabolism-syndrome-and-its-implications-for-therapy
#20
REVIEW
Hiroyuki Horiguchi, Tyler J Loftus, Russell B Hawkins, Steven L Raymond, Julie A Stortz, McKenzie K Hollen, Brett P Weiss, Elizabeth S Miller, Azra Bihorac, Shawn D Larson, Alicia M Mohr, Scott C Brakenridge, Hironori Tsujimoto, Hideki Ueno, Frederick A Moore, Lyle L Moldawer, Philip A Efron
Clinical and technological advances promoting early hemorrhage control and physiologic resuscitation as well as early diagnosis and optimal treatment of sepsis have significantly decreased in-hospital mortality for many critically ill patient populations. However, a substantial proportion of severe trauma and sepsis survivors will develop protracted organ dysfunction termed chronic critical illness (CCI), defined as ≥14 days requiring intensive care unit (ICU) resources with ongoing organ dysfunction...
2018: Frontiers in Immunology
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