Read by QxMD icon Read


Qianqian Dong, Feng Wang, Yihua Xiao, Penghui Li, Qinghui Huang
Eutrophication enhances the production of autochthonous dissolved organic matter (DOM), which is a major driving factor behind the impairment of many aquatic ecosystems. In a mesocosm study, we investigated the effects of the abundance and composition of DOM on the potential bioavailability of cadmium (Cd) caused by eutrophication, using three-dimensional excitation-emission matrix fluorescence spectroscopy integrated with tangential flow ultrafiltration technology. The complexing capacity of DOM-Cd and the sorption distribution coefficient between DOM and the bulk solution was calculated based on a 1 : 1 complexation model...
August 9, 2018: Environmental Science. Processes & Impacts
Xiaorong Yang, Jun Liu, Yulan Huang, Jiantong Meng, Gaopeng Lei, Yong Jia, Weifeng Huang, Yong Wang, Lin Zhang, Hong Lv, Shusen He
Methicillin-resistant Staphylococcus aureus (MRSA) is a major multidrug-resistant (MDR) opportunistic pathogen that is responsible for nosocomial infections worldwide. The emergence of MRSA in food-producing animals has heightened concerns regarding the presence of MRSA in foods having an animal origin. The objectives of this study were to determine the prevalence of MRSA in different sources, including retail food, food-producing animals, and food handlers in Sichuan province. During 2007-2015, S. aureus was isolated from samples having different origins...
August 8, 2018: Foodborne Pathogens and Disease
Darius Juskevicius, David Jucker, Tanja Dietsche, Valeria Perrina, Alex Rufle, Christian Ruiz, Stefan Dirnhofer, Alexandar Tzankov
Approximately 15% of patients with classical Hodgkin lymphoma (cHL) die after relapse or progressive disease. Comprehensive genetic characterization is required to better understand its molecular pathology and improve management. However, genetic information on cHL is hard to obtain mainly due to rare malignant Hodgkin- and Reed-Sternberg cells (HRSC), whose overall frequencies in the affected tissues ranges from 0.1 to 10%. Therefore, enrichment of neoplastic cells is necessary for the majority of genetic investigations...
August 7, 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
Kieu-Suong Le, Patricia Amé-Thomas, Karin Tarte, Françoise Gondois-Rey, Samuel Granjeaud, Florence Orlanducci, Etienne D Foucher, Florence Broussais, Reda Bouabdallah, Thierry Fest, Dominique Leroux, Sapna Yadavilli, Patrick A Mayes, Luc Xerri, Daniel Olive
A better characterization of T-cell subsets in the microenvironment of classical Hodgkin lymphoma (cHL) would help to develop immunotherapies. Using multicolor flow cytometry, we identified in 6 of 43 cHL tissue samples a previously unrecognized subset of CD8 T cells coexpressing CXCR5 and inducible T-cell costimulator (ICOS) molecules (CD8CXCR5+ICOS+ ). These cells shared phenotypic features with follicular helper T (TFH ) cells including low CCR7 expression together with high expression of B-cell lymphoma-6, programmed cell death 1, B and T lymphocyte attenuator, CD200, and OX40...
August 14, 2018: Blood Advances
Eriko Matsuo, Yuji Inagaki
Background: The ancestral dinoflagellate most likely established a peridinin-containing plastid, which have been inherited in the extant photosynthetic descendants. However, kareniacean dinoflagellates and Lepidodinium species were known to bear "non-canonical" plastids lacking peridinin, which were established through haptophyte and green algal endosymbioses, respectively. For plastid function and maintenance, the aforementioned dinoflagellates were known to use nucleus-encoded proteins vertically inherited from the ancestral dinoflagellates (vertically inherited- or VI-type), and those acquired from non-dinoflagellate organisms (including the endosymbiont)...
2018: PeerJ
Santosha Vardhana, Kara Cicero, Moises J Velez, Craig H Moskowitz
The programmed death-1 (PD-1) receptor checkpoint inhibitors nivolumab and pembrolizumab represent an important therapeutic advance in the treatment of relapsed or refractory classical Hodgkin lymphoma (cHL). Clinical trials have shown substantial therapeutic activity and an acceptable safety profile in heavily pretreated patients, resulting in U.S. Food and Drug Administration approval of nivolumab for the treatment of cHL that has relapsed or progressed after either autologous hematopoietic cell transplantation (auto-HCT) and brentuximab vedotin treatment or three or more lines of systemic therapy (including auto-HCT), and of pembrolizumab for adult or pediatric patients with refractory cHL or cHL that has relapsed after three or more prior therapies...
August 6, 2018: Oncologist
Theresia Erhart, Cecilia Mittelberger, Xiujun Liu, Maren Podewitz, Chengjie Li, Gerhard Scherzer, Gertrud Stoll, Josep Valls, Peter Robatscher, Klaus Liedl, Michael Oberhuber, Bernhard Kräutler
The tetrapyrrolic chlorophyll catabolites (or phyllobilins, PBs) were analyzed in yellow fall leaves of the grape Chardonnay, a common Vitis vinifera white wine cultivar. The major fractions in leaf extracts of V. vinifera, tentatively assigned to PBs, were isolated and their structures elucidated. The dominant fraction is a dioxobilin-type non-fluorescent Chl-catabolite of a previously observed type. Two less polar fluorescent PBs were characterized as a novel dioxobilin-type fluorescent Chl-catabolite with a bicyclo-1',6'-glycosyl architecture, and its new fluorescent formyloxobilin-type analog...
August 6, 2018: Chemistry: a European Journal
Charles Ampomah-Dwamena, Amali H Thrimawithana, Supinya Dejnoprat, David Lewis, Richard V Espley, Andrew C Allan
MYB transcription factors (TFs) regulate diverse plant developmental processes and understanding their roles in controlling pigment accumulation in fruit is important for developing new cultivars. In this study, we characterised kiwifruit TFMYB7, which was found to activate the promoter of the kiwifruit lycopene beta-cyclase (AdLCY-β) gene that plays a key role in the carotenoid biosynthetic pathway. To determine the role of MYB7, we analysed gene expression and metabolite profiles in Actinidia fruit which show different pigment profiles...
August 1, 2018: New Phytologist
Neda Mirzamani, Xinmin Zhang, Judith Brody, Silvia G Spitzer, Filiz Sen, Peihong Hsu
Hodgkin/Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (CHL) are of B-cell origin. In a small number of CHL cases, the tumor cells can express T-cell antigens. CD8 expression in this setting is extremely rare. We identified 5 cases of CHL with aberrant CD8 expression from our database. The patients included 3 men and 2 women with a median age of 33 years (range = 20-59 years). All the patients initially presented with lymphadenopathy and variable number of RS cells. Two cases were classified as mixed cellularity type that showed prominent vascular proliferation mimicking peripheral T-cell lymphoma...
July 30, 2018: International Journal of Surgical Pathology
Susanne Menden-Deuer, Caitlyn Lawrence, Gayantonia Franzè
To assess protistan grazing impact and temperature sensitivity on plankton population dynamics, we measured bulk and species-specific phytoplankton growth and herbivorous protist grazing rates in Disko Bay, West Greenland in April-May 2011. Rate estimates were made at three different temperatures in situ (0 °C), +3 °C and +6 °C over ambient. In situ Chlorophyll a (Chl a ) doubled during the observation period to ∼12  µg Chl a L-1 , with 60-97% of Chl a in the >20 µm size-fraction dominated by the diatom genus Chaetoceros...
2018: PeerJ
Brice E N Wamba, Armelle T Mbaveng, Paul Nayim, Joachim K Dzotam, Ornella J T Ngalani, Victor Kuete
Background: In this study, 18 methanol extracts from Cameroonian edible plants were tested for their antibacterial activities against 26 strains of S. aureus ; the role of efflux pumps in the resistance of tested bacteria and the antibiotic resistance-modulating activities against selected multidrug-resistant (MDR) phenotypes were also investigated. Methods: Broth microdilution assay was used to evaluate the antibacterial activity, the role of efflux pumps, and the antibiotic resistance-modulating effects of plant extracts...
2018: International Journal of Microbiology
Chunxiang Liu, Dinghui Zou, Yufeng Yang
Physiological metabolisms of seaweeds usually suffered climate changes in the field. Gracilariopsis lemaneiformis and Ulva lactuca, collected from Nan'ao Island, Shantou, China, were cultured under ambient and elevated CO2 supply (390 and 800 μl L-1 ), with low and high temperatures (15 °C and 25 °C) for 2 weeks, aiming to compare the difference of the main physiological metabolism between two seaweed species in response to the elevated CO2 and high temperature. At 15 °C, the pH reduction in the culture medium caused by elevated CO2 was larger in G...
July 25, 2018: Environmental Science and Pollution Research International
Yu Wang, Jian-Hua Kang, Qian-Yong Liang, Xue-Bao He, Jian-Jun Wang, Mao Lin
We analyzed the data obtained from field observations on a gas hydrate drilling area in Dongsha of northern South China Sea (SCS) in middle May (before drilling) and early October (after drilling) in 2013. The variation in the phytoplankton communities and biomass as well as the impacts of environmental factors including dissolved methane was studied. Results indicated that the gas hydrate drilling area in Dongsha, SCS exhibited a typical low-nutrients low-chlorophyll a (LNLC) environment accompanied with low phytoplankton abundance...
August 2018: Marine Pollution Bulletin
Lunhui Lu, Linlin Xu, Jixiang Yang, Zhe Li, Jinsong Guo, Yan Xiao, Juanjuan Yao
This study investigated phytoplankton and bacterioplankton communities by flow cytometer in a tributary backwater area of the Three Gorges Reservoir, China. Samplings were conducted in two cyanobacterial bloom periods (May and August) and no algal-blooms period (November) of 2014, representing three different operational stages of the reservoir, i.e., reservoir discharge period, fluctuating period in the summer flood season, and high water level in the impoundment period. Phyto- and bacterioplankton exhibit a wide range of variability along the depth profiles of the water column...
July 23, 2018: Environmental Science and Pollution Research International
Franz-Josef Schmitt, Züleyha Yenice Campbell, Mai Vi Bui, Anne Hüls, Tatsuya Tomo, Min Chen, Eugene G Maksimov, Suleyman I Allakhverdiev, Thomas Friedrich
The phototrophic cyanobacterium Halomicronema hongdechloris shows far-red light-induced accumulation of chlorophyll (Chl) f, but the involvement of the pigment in photosynthetic energy harvesting by photosystem (PS) II is controversially discussed. While H. hongdechloris contains negligible amounts of Chl f in white-light culture conditions, the ratio of Chl f to Chl a is reversibly changed up to 1:8 under illumination with far-red light (720-730 nm). We performed UV-Vis absorption spectroscopy, time-integrated and time-resolved fluorescence spectroscopy for the calculation of decay-associated spectra (DAS) to determine excitation energy transfer (EET) processes between photosynthetic pigments in intact H...
July 23, 2018: Photosynthesis Research
Annemarie Perez Boerema, Shintaro Aibara, Bijoya Paul, Victor Tobiasson, Dari Kimanius, Björn O Forsberg, Karin Wallden, Erik Lindahl, A Amunts
In the version of this Article originally published, the name of co-author Annemarie Perez Boerema was coded wrongly, resulting in it being incorrect when exported to citation databases. This has been corrected, though no visible changes will be apparent.
July 23, 2018: Nature Plants
Eman Al-Antary, Rohith Jesudas, Amy George, Janet Poulik, Süreyya Savaşan
Syncytial variant of nodular sclerosis (SV-NS) classical Hodgkin lymphoma (cHL) with its histologic features and clinical presentation is uncommon in adults and extremely rare in children. Here, we report a female teenager presenting with long-standing B symptoms, prominent soft tissue and bone involvement mimicking sarcoma and significant nodal disease who is diagnosed with advanced SV-NS cHL. Rare Reed-Sternberg-like cells displaying neutrophil and erythrocyte emperipolesis were seen on bone marrow aspiration slides...
July 19, 2018: Journal of Pediatric Hematology/oncology
Amechi S Nwankwegu, Yiping Li, Long Jiang, Qiuying Lai, Weng Shenglin, Wei Jin, Kumud Acharya
The integration of first and second order kinetic model in parameter estimation for the degradation pattern of total petroleum hydrocarbon (TPH) in spent lubricating petroleum oil (SLPO) over a four-month period was the subject of the present investigation. Study design considered four treatment microcosms notably; sewage sludge (SB), monitored natural recovery (MNR), surfactant (SA) and control (SO). The rate of TPH degradation using sewage sludge as amendment material depicted effective TPH removal within ten weeks...
July 26, 2018: Environmental Technology
Seyyed Jalal Sameni, Ahmad Daneshi, Akram Pourbakht, Aliakbar Tahaei, Mohammad Kamali
Background and Objectives: In clinical masking, the plateau is a state in which the non-test ear (NTE) is completely masked by the noise and tone is heard only by the test ear (TE). At least 15 to 20 dB of plateau width is needed to obtain valid threshold. In the study, a part of plateau after initial masking level known as the minimum plateau width (mPW) was determined and compared by a new formula and the plateau searching method. Subjects and Methods: Minimum plateau widths of air conduction were obtained in 29 participants with unilateral and 30 participants with bilateral conductive hearing loss (CHL) aged 20 to 45 years old by using step by step plateau method and mPW estimation by the formula between two points of masking diagram [mPW=(N2-N1)-(T2-T1)] and then the mPW of two methods was compared for each frequency...
July 19, 2018: Journal of Audiology & Otology
Qiaozhen Guo, Zhenxia Du, Bing Shao
Azithromycin (AZI) has been listed as an emerging contaminant by the US EPA since 2009 because it is frequently detected in wastewater, surface water, and drinking water. In this paper, the chlorination of AZI in drinking water was simulated and studied. The results indicated that new compounds were generated in the chlorination of AZI. The byproducts were identified by liquid chromatography-quadrupole-time-of-flight mass spectrometry (LC-Q-TOF), and four of the byproducts were detected in real water samples...
July 9, 2018: Journal of Hazardous Materials
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"