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Shear wave elastography

Wen-Hui Chan, Yen-Ling Huang, Chieh Lin, Chia-Yu Lin, Ming-Huei Cheng, Sung-Yu Chu
Purpose To evaluate the feasibility of cutaneous and subcutaneous limb tissue elasticity measurement in participants with limb lymphedema by using acoustic radiation force impulse (ARFI) elastography. Materials and Methods From July 2015 to June 2017, ARFI elastography was performed in 64 participants with lymphedema (seven men and 57 women; age range, 23-85 years) by using a US system. Tissue stiffness quantification with shear-wave velocity (SWV) was obtained in the cutaneous and subcutaneous limb tissues...
August 14, 2018: Radiology
Wei Zheng, Zhong-Guo Zhou, Chong-Hei Wong, Xiao-Qing Pei, Shu-Lian Zhuang, Qing Li, Min-Shan Chen, An-Hua Li, Fu-Jun Zhang
OBJECTIVES: To determine the methodology of non-invasive test for evaluation of liver stiffness (LS) with tumours using two-dimensional (2D) shear wave elastography (SWE). METHODS: One hundred and twenty-seven patients with liver tumours underwent 2D-SWE before surgery to measure liver and spleen stiffness (SS). Two-dimensional SWE values were obtained in the liver at 0-1 cm, 1-2 cm and >2 cm from the tumour edge (PLS-1, PLS-2 and RLS, respectively). The influence of tumour-associated factors was evaluated...
August 13, 2018: European Radiology
A Manduca, T L Rossman, D S Lake, K J Glaser, A Arani, S P Arunachalam, P J Rossman, J D Trzasko, R L Ehman, D Dragomir-Daescu, P A Araoz
Magnetic resonance elastography (MRE) is increasingly being applied to thin or small structures in which wave propagation is dominated by waveguide effects, which can substantially bias stiffness results with common processing approaches. The purpose of this work was to investigate the importance of such biases and artifacts on MRE inversion results in: (i) various idealized 2D and 3D geometries with one or more dimensions that are small relative to the shear wavelength; and (ii) a realistic cardiac geometry...
August 13, 2018: NMR in Biomedicine
Jaromir Vachutka, Zuzana Sedlackova, Tomas Furst, Miroslav Herman, Jan Herman, Richard Salzman, Ladislav Dolezal
Shear wave imaging is considered to be more precise and less operator dependent when compared with strain imaging. It enables quantitative and reproducible data (Young's modulus of the imaged tissue). However, results of shear wave imaging can be affected by a variety of different factors. The aim of this study is to evaluate the effect of the pressure applied by the ultrasound probe during examination on the measured values of Young's modulus. The effect of the tissue compression on the results of the real-time shear wave elastography was evaluated via the gelatine phantom measurements, via the ex vivo experiments with pig liver, and via the in vivo measurements of the thyroid gland stiffness on healthy volunteers...
August 12, 2018: Ultrasonic Imaging
Jessica L Schachter, Manisha Patel, Samuel R Horton, A Mike Devane, Alex Ewing, Gary A Abrams
OBJECTIVE: As the population of patients with Fontan circulation surviving into adulthood increases, hepatic cirrhosis has grown to be a significant cause of morbidity and mortality. Early detection of advanced hepatic fibrosis is imperative for proper intervention and consideration for heart or combined heart/liver transplantation. Noninvasive biomarkers and elastography have been evaluated for their diagnostic utility with variable results in the Fontan population. DESIGN: The cohort included 14 patients age 26...
August 12, 2018: Congenital Heart Disease
Hongliang Li, Jonathan Porée, Marie-Hélène Roy Cardinal, Guy Cloutier
Polar strain (radial and circumferential) estimations can suffer from artifacts because the center of a nonsymmetrical carotid atherosclerotic artery, defining the coordinate system in cross-sectional view, can be misregistered. Principal strains are able to remove coordinate dependency to visualize vascular strain components (i.e., axial and lateral strains and shears). This paper presents two affine model-based estimators, the affine phase-based estimator (APBE) developed in the framework of transverse oscillation (TO) beamforming, and the Lagrangian speckle model estimator (LSME)...
July 21, 2018: Ultrasonics
Jinling Zhou, Xiaoming Zhang
Lung ultrasound surface wave elastography (LUSWE) is a novel technique used to measure superficial lung tissue stiffness. A phantom study was carried out in the study described here to evaluate the application of LUSWE to assess lung water for pulmonary edema. A lung phantom model with cellulose sponge was used; various volumes of water were injected into the sponge to model lung water. Shaker-generated surface wave propagation on the sponge surface was recorded by a 10-MHz ultrasound probe at three shaker frequencies: 100, 150 and 200 Hz...
August 1, 2018: Ultrasound in Medicine & Biology
Christoph F Dietrich, Corinna Trenker, Teresa Fontanilla, Christian Görg, Andreas Hausmann, Stefan Klein, Nathalie Lassau, Rosa Miquel, Dagmar Schreiber-Dietrich, Yi Dong
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation. Clinically, SOS/VOD is characterized by hepatomegaly, right upper quadrant pain, jaundice and ascites, most often occurring within the first 3 wk after hematopoietic cell transplantation. Early therapeutic intervention is pivotal for survival in SOS/VOD. Thus, a rapid and reliable diagnosis has to be made. Diagnosis of SOS/VOD is based on clinical criteria, such as the Seattle, Baltimore or recently issued European Society for Blood and Marrow Transplantation criteria, to which hemodynamic and/or ultrasound evidence of SOS were added for the first time...
July 31, 2018: Ultrasound in Medicine & Biology
Ranjit S Sandhu, James Shin, Natasha E Wehrli, Jing Gao
Background: Shear-wave elastography of the kidney has emerged as a potential clinical application of this novel imaging tool. However, normal velocity values for shear-wave elastography involving the cortex of healthy kidneys have not been definitively established, and both inter- and intraobserver reliability has yet to be comprehensively evaluated. Methods: This prospective study involved ultrasound examination of 11 healthy adults. Shear-wave velocity values were obtained at the renal cortex in the longitudinal and transverse planes by both junior (fellow) and senior (attending) radiologists...
April 2018: Journal of Medical Ultrasound
Harsh Singh, Om Biju Panta, Umesh Khanal, Ram Kumar Ghimire
Introduction: Renal cortical elastography has shown conflicting but promising results in evaluation of chronic kidney disease and other renal disorders. The purpose of this study was to establish a normogram of renal cortical elasticity values and assess their variation between right and left kidney and their relation with age, gender, body mass index, renal dimensions and skin to cortex distance. Methods: The study was a hospital based cross sectional study performed at Tribhuvan University Teaching Hospital, a tertiary care center in Kathmandu, Nepal...
October 2017: Journal of Medical Ultrasound
Ralph Sinkus, Simon Lambert, Khaled Z Abd-Elmoniem, Caryn Morse, Theo Heller, Christian Guenthner, Ahmed M Ghanem, Sverre Holm, Ahmed M Gharib
The purpose of this study is to investigate the use of fundamental rheological parameters as quantified by MR elastography (MRE) to measure liver fibrosis and inflammation simultaneously in humans. MRE was performed on 45 patients at 3 T using a vibration frequency of 56 Hz. Fibrosis and inflammation scores were obtained from liver biopsies. Biomechanical properties were quantified in terms of complex shear modulus G* as well as shear wave phase velocity c and shear wave attenuation α. A rheological fractional derivative order model was used to investigate the linear dependence of the free model parameters (dispersion slope y, intrinsic speed c0 , and intrinsic relaxation time τ) on histopathology...
July 30, 2018: NMR in Biomedicine
Ayse Selcan Koc, Hılmı Erdem Sumbul
PURPOSE: It is known that patients with type 2 diabetes mellitus (DM) who develop diabetic nephropathy have increased renal cortical stiffness (CS) determined by shear wave elastography (SWE). However, there is no data in the literature to our knowledge related to CS values determined by SWE in type 2 DM patients with normal renal function. In this study, we aimed to investigate the change of renal CS obtained by SWE examination in type 2 DM patients with normal renal function compared to non DM patients...
July 26, 2018: Journal of Ultrasound
André Farrokh, Nicolai Maass, Linn Treu, Thorsten Heilmann, Fritz Kw Schäfer
Background Predicting the exact extent of a breast tumor is of great importance for oncologic treatment strategies. Different types of elastography can be used as new tools for measuring lesion size. Purpose To provide evidence regarding the accuracy of tumor size measurement of strain elastography (SE), two-dimensional (2D) and three-dimensional (3D) shear wave elastography (SWE), and conventional B-image ultrasound. Material and Methods In this prospective study, the diameter of 105 malignant breast lesions was measured by SE, 2D and 3D SWE, and B-mode ultrasound...
July 25, 2018: Acta Radiologica
Yanrong Guo, Haoming Lin, Changfeng Dong, Xinyu Zhang, Huiying Wen, Yuanyuan Shen, Tianfu Wang, Siping Chen, Yingxia Liu, Xin Chen
Acoustic radiation force impulse (ARFI) elastography is a non-invasive method for performing liver assessment via liver shear wave velocity (SWV) measurements. The aim of this study was to evaluate the performance of the ARFI technique in the diagnosis of nonalcoholic steatohepatitis (NASH) and fibrosis and to investigate the effect of steatosis and inflammation on liver fibrosis SWV measurements in a rat model of nonalcoholic fatty liver disease (NAFLD). The ex vivo right liver lobes from 110 rats were processed and embedded in a fabricated gelatin phantom, and the other lobes were used for histologic assessment...
July 2, 2018: Medical Engineering & Physics
Yongyan Gao, Jian Zheng, Ping Liang, Minghui Tong, Jiabing Wang, Changjun Wu, Xin He, Changzhu Liu, Shumei Zhang, Liping Huang, Tian'an Jiang, Chao Cheng, Fankun Meng, Xiaojie Mu, Yongping Lu, Yunyan Li, Hong Ai, Xudong Qiao, Xiao-Yan Xie, Wei Wang, Li-Ping Yin, Yi-Yun Wu, Rongqin Zheng
Purpose To investigate the diagnostic performance of two-dimensional (2D) shear-wave elastography (SWE) in chronic hepatitis B. Materials and Methods This prospective multicenter study from January 2015 to January 2016 was conducted at 12 hospitals and included 654 participants with chronic hepatitis B who had undergone liver biopsy and 2D SWE examination. Participants were divided into chronic infection and chronic hepatitis groups. The diagnostic performance of 2D SWE was compared with the aspartate amino transferase-to-platelet ratio index (APRI), the Fibrosis-4 index (FIB-4), and transient elastography (TE) by using a DeLong test and was also compared between two subgroups...
July 24, 2018: Radiology
Anil Chauhan
No abstract text is available yet for this article.
July 24, 2018: Radiology
Young Seo Cho, Sanghyeok Lim, Yongsoo Kim, Joo Hyun Sohn, Jae Yoon Jeong
OBJECTIVES: To investigate the success rate of spleen stiffness measurement and factors that affect measurement success and to determine the spleen stiffness value of normal individuals by 2-dimensional shear wave elastography. METHODS: The spleen and liver stiffnesses of 313 consecutive patients were measured with SWE. The body mass index, abdominal wall thickness, spleen size, and liver stiffness of the patients were evaluated to identify factors associated with successful measurement of spleen stiffness...
July 23, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Jie Zeng, Jian Zheng, Jie-Yang Jin, Yong-Jiang Mao, Huan-Yi Guo, Ming-De Lu, Hai-Rong Zheng, Rong-Qin Zheng
OBJECTIVES: To determine and validate alanine aminotransferase (ALT)-adapted dual cut-offs of liver stiffness measurements (LSMs) for assessing liver fibrosis with two-dimensional shear wave elastography (2D-SWE) in patients with chronic hepatitis B (CHB) infection. METHODS: Patients with CHB infection who underwent liver biopsy to assess liver fibrosis were consecutively included. 2D-SWE confirmation thresholds with a positive likelihood ratio ≥10 and 2D-SWE exclusion thresholds with a negative likelihood ratio ≤0...
July 23, 2018: European Radiology
T Ackerman, A Geerts, H Van Vlierberghe, J De Backer, K François
We tried to identify structural and functional liver aberrances in a palliated Fontan population and sought to determine useful screening modalities, in order to propose a screening protocol to detect patients at risk. Twenty nine patients, median age 23.7 years (interquartile range (IQR) 20.5-27.2) and median Fontan interval 19.7 years (IQR 4.5-21.4), were prospectively studied with echocardiography, blood analysis (including serum fibrosis scores Forns, APRI and FIB4), liver imaging (ultrasound (US), Doppler), and shear wave elastography to determine liver stiffness (LS)...
July 21, 2018: Pediatric Cardiology
E A Vola, M Albano, C Di Luise, V Servodidio, M Sansone, S Russo, B Corrado, C Servodio Iammarrone, M G Caprio, G Vallone
PURPOSE: Cerebral palsy (CP) is a disorder characterized by an increased muscle stiffness that can be contingent on both neurological and biomechanical factors. The neurological aspects are related to hyper-excitability of the stretch reflex, while the biomechanical factors are related to modifications in muscle structure. We used smart-shear wave elastography (S-SWE) to analyze muscle properties and to compare shear wave speed in soleus muscles of patients affected by CP and typically developing children...
July 20, 2018: Journal of Ultrasound
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