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Mountain medicine

Ho Sung Lee, Young Joo Lee, Yoon Hee Chung, Moo Yeol Lee, Sung Tae Kim, Sung Kwon Ko, Mariko Momoi, Yutaka Kondoh, Fumio Sasaki, Ji Hoon Jeong
BACKGROUND: Progressed tissue culture techniques have allowed us to easily obtain mass products of tissue-cultured mountain ginseng over 100 yr old (TCMG-100). We investigated the effects of TCMG-100 extract on erectile function using in vitro and in vivo studies. METHODS: To examine the relaxation effects and mechanisms of action of TCMG-100 on rabbit cavernosal strips evaluated in an organ bath. To investigate the long-term treatment effect of TCMG-100, 8-wk administration was performed...
October 2016: Journal of Ginseng Research
Hongliang Li, Shuqiang Cao, Xuanbin Wang, Qimin Zuo, Ping Chen, Ying Liu, Ming Liu, Yibin Feng, Xincai Hao, Longchao Xiang, Xiaohua Zeng
Polygonum multiflorum Thunb., which is known as Heshouwu in China, is a Taoist medicine sourced from the Wudang mountain area. At present, the quality of the Heshouwu sourced from this region is unknown. The present study aimed to evaluate the quality of wild Heshouwu collected from the Wudang mountain area, particularly the 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) and combined anthraquinone (CAQ) content, compared with that of commercially available Heshouwu. Furthermore, the potential quantities of organic pesticide residues were determined...
October 2016: Experimental and Therapeutic Medicine
M Kobek, R Skowronek, C Jabłoński, Z Jankowski, A Pałasz
On 28 January 2003 snow avalanche in the Polish Tatras happened, in which 8 people died and 5 were injured. We tried to determine cause and manner of death in 6 fatal victims instead of advanced late post mortem changes in internal organs. Taking into consideration the circumstances of death, we paid special attention to histopathological examination of lungs, extended by Gomori's and AZAN staining. Pattern of the changes was similar to those observed in forensic medicine in cases of asphyxia due to airway obstruction and/or immobilization of chest and abdomen (Perthes' syndrome)...
2016: Archiwum Medycyny Sa̧dowej i Kryminologii
Rajal Debnath, Archana Yadav, Vijai K Gupta, Bhim P Singh, Pratap J Handique, Ratul Saikia
Information on rhizosphere microbiome of endemic plants from high mountain ecosystems against those of cultivated plantations is inadequate. Comparative bacterial profiles of endemic medicinal plant Rhododendron arboreum Sm. subsp. delavayi rhizosphere pertaining to four altitudinal zonation Pankang Thang (PTSO), Nagula, Y-junction and Bum La (Indo-China border; in triplicates each) along cold adapted Eastern slope of Himalayan Tawang region, India is described here. Significant differences in DGGE profile between below ground bulk vs...
2016: Frontiers in Plant Science
Urs Pietsch, Jürgen Knapp, Ludwig Ney, Armin Berner, Volker Lischke
OBJECTIVE: Mountain helicopter rescue operations often confront crews with unique challenges in which even minor errors can result in dangerous situations. Simulation training provides a promising tool to train the management of complex multidisciplinary settings, thus reducing the occurrence of fatal errors and increasing the safety for both the patient and the helicopter emergency medical service (HEMS) crew. METHODS: A simulation-based training, dedicated to mountain helicopter emergency medicine service, was developed and executed...
September 2016: Air Medical Journal
Peter Paal, Les Gordon, Giacomo Strapazzon, Monika Brodmann Maeder, Gabriel Putzer, Beat Walpoth, Michael Wanscher, Doug Brown, Michael Holzer, Gregor Broessner, Hermann Brugger
BACKGROUND: This paper provides an up-to-date review of the management and outcome of accidental hypothermia patients with and without cardiac arrest. METHODS: The authors reviewed the relevant literature in their specialist field. Summaries were merged, discussed and approved to produce this narrative review. RESULTS: The hospital use of minimally-invasive rewarming for non-arrested, otherwise healthy, patients with primary hypothermia and stable vital signs has the potential to substantially decrease morbidity and mortality for these patients...
September 15, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Zaheer Abbas, Shujaul Mulk Khan, Arshad Mehmood Abbasi, Andrea Pieroni, Zahid Ullah, Muhammad Iqbal, Zeeshan Ahmad
BACKGROUND: Limited health facilities and malnutrition are major problems in the Karakorum Range of Northern Pakistan, often resulting in various human disorders. Since centuries, however, local communities in these areas have developed traditional methods for treating various ailments and local foods capes that can be significant for devising public health and nutritional policies. This study was intended to document the ethnobotanical knowledge of the local peoples in the Tormik Valley, especially in the medical and food domains...
2016: Journal of Ethnobiology and Ethnomedicine
Pierre Andonian, Magalie Viallon, Caroline Le Goff, Charles de Bourguignon, Charline Tourel, Jérome Morel, Guido Giardini, Laurent Gergelé, Grégoire P Millet, Pierre Croisille
In sports medicine, there is increasing interest in quantifying the elastic properties of skeletal muscle, especially during extreme muscular stimulation, to improve our understanding of the impact of alterations in skeletal muscle stiffness on resulting pain or injuries, as well as the mechanisms underlying the relationships between these parameters. Our main objective was to determine whether real-time shear-wave elastography (SWE) can monitor changes in quadriceps muscle elasticity during an extreme mountain ultra-marathon, a powerful mechanical stress model...
2016: PloS One
Carla Gonzales-Arimborgo, Irma Yupanqui, Elsa Montero, Dulce E Alarcón-Yaquetto, Alisson Zevallos-Concha, Lidia Caballero, Manuel Gasco, Jianping Zhao, Ikhlas A Khan, Gustavo F Gonzales
The plant maca, grown at 4000 m altitude in the Peruvian Central Andes, contains hypocotyls that have been used as food and in traditional medicine for centuries. The aim of this research was to provide results on some health effects of oral administration of spray-dried extracts of black or red maca (Lepidium meyenii) in adult human subjects living at low (LA) and high altitude (HA). A total of 175 participants were given 3 g of either placebo, black, or red maca extract daily for 12 weeks. Primary outcomes were changes in sexual desire, mood, energy, health-related quality of life score (HRQL), and chronic mountain sickness (CMS) score, or in glycaemia, blood pressure, and hemoglobin levels...
August 18, 2016: Pharmaceuticals
Shuyu Zhou, Zhilei Li, Lu Bai, Kai Yan, Junwei Zhao, Chang Lu, Chongxi Liu, Xiangjing Wang, Wensheng Xiang
During an investigation of microbial diversity in medicinal herbs, a novel actinomycete, strain NEAU-QHHV11(T) was isolated from the rhizosphere of Peucedanum praeruptorum Dunn collected from Xianglu Mountain in Heilongjiang Province, northeast China and characterized using a polyphasic approach. The organism was found to have typical characteristics of the genus Streptomyces. Phylogenetic analysis based on 16S rRNA gene sequence also indicated that strain NEAU-QHHV11(T) belongs to the genus Streptomyces and was most closely related to Streptomyces graminilatus NBRC 108882(T) (98...
July 30, 2016: Archives of Microbiology
James D Johnson
The production of fully functional insulin-secreting cells to treat diabetes is a major goal of regenerative medicine. In this article, I review progress towards this goal over the last 15 years from the perspective of a beta cell biologist. I describe the current state-of-the-art, and speculate on the general approaches that will be required to identify and achieve our ultimate goal of producing functional beta cells. The need for deeper phenotyping of heterogeneous cultures of stem cell derived islet-like cells in parallel with a better understanding of the heterogeneity of the target cell type(s) is emphasised...
October 2016: Diabetologia
Adrián Paredes, Javier Palacios, Cristina Quispe, Chukwuemeka R Nwokocha, Glauco Morales, Jovan Kuzmicic, Fredi Cifuentes
ETHNOPHARMACOLOGICAL RELEVANCE: Senecio nutans Sch. Bip. (Compositae) is an endemic plant of South America, and is used in herbal medicine in Andean communities for treating acute mountain sickness. Currently, the direct effects of hydroalcoholic extract of S. nutans (HAE S. nutans) or its isolated compounds on the vascular system are not well described. The aim of this study was to determine the effects and mechanism of action of S. nutans on vascular function in healthy rats. MATERIAL AND METHODS: Seven compounds were isolated from the HAE S...
July 5, 2016: Journal of Ethnopharmacology
Liping Li, Bengang Zhang, Peigen Xiao, Yaodong Qi, Zhao Zhang, Haitao Liu, Xiaojin Li, Guoping Wang, André Terwei
With both a full collection of native vascular plant distributions and a full checklist of source plants of the Chinese Materia Medica (CMM), the Uygur Medicine (UM), and the Kazak Medicine (KM) for the Xinjiang region, we defined medicinal plant: vascular plant ratios (simplified as medicinal plant ratios hereafter) as the value of medicinal plant richness divided by vascular plant richness. We aimed to find whether the ratios are constant or change in different environments, which environmental variables determine medicinal plant ratios, and whether the ratios are more influenced by human or by natural environments...
2016: PloS One
Hong-Dan Zhan, Hai-Yu Zhou, Yun-Peng Sui, Xin-Liang Du, Wei-Hao Wang, Li Dai, Feng Sui, Hai-Ru Huo, Ting-Liang Jiang
ETHNOPHARMACOLOGICAL RELEVANCE: Gastrodia elata Blume (Orchidaceae) is commonly called Tian ma in Chinese and mainly distributed in the mountainous areas of eastern Asia, such as China, Korea, Japan and India. It is an extensively used traditional Chinese herbal medicine in the clinical practice of traditional Chinese medicine, to treat headache, migraine, dizziness, epilepsy, infantile convulsion, tetany and so on. The present paper reviews the advancements in investigation of botany and ethnopharmacology, phytochemistry, pharmacology, toxicology and quality control of Gastrodia elata Blume...
August 2, 2016: Journal of Ethnopharmacology
Gabriel Shaibi, Davinder Singh, Eleanna De Filippis, Valentina Hernandez, Bill Rosenfeld, Essen Otu, Gregorio Montes de Oca, Sharon Levey, Carmen Radecki Breitkopf, Richard Sharp, Janet Olson, James Cerhan, Stephen Thibodeau, Erin Winkler, Lawrence Mandarino
BACKGROUND/AIMS: The Sangre Por Salud (Blood for Health; SPS) Biobank was created for the purpose of expanding precision medicine research to include underrepresented Latino patients. It is the result of a unique collaboration between Mayo Clinic and Mountain Park Health Center, a federally qualified community health center in Phoenix, Arizona. This report describes the rationale, development, implementation, and characteristics of the SPS Biobank. METHODS: Latino adults (ages 18-85 years) who were active patients within Mountain Park Health Center's internal medicine practice in Phoenix, Ariz...
2016: Public Health Genomics
Irene Teixidor-Toneu, Gary J Martin, Ahmed Ouhammou, Rajindra K Puri, Julie A Hawkins
This dataset describes medicinal plants used in a poorly studied area of Morocco: the High Atlas mountains, inhabited by Ishelhin people, the southern Moroccan Amazigh (Berber) ethnic group, "An ethnomedicinal survey of a Tashelhit-speaking community in the High Atlas, Morocco" (Teixidor-Toneu et al., 2016) [1]. It includes a comprehensive list of the plants used in the commune, as well as details on the plant voucher specimens collected and a glossary of Tashelhit terminology relevant to the study. To collect the data, semi-structured and structured interviews were carried out, as well as focus group discussions...
September 2016: Data in Brief
Valeria Romanucci, Giovanni Di Fabio, Daniele D'Alonzo, Annalisa Guaragna, Giovanni Scapagnini, Armando Zarrelli
Sideritis species have been used in folk medicine for their antimicrobial, antiulcerogenic, digestive and anti-inflammatory properties. Over the years, the phytochemistry of the genus Sideritis has been studied, and various terpenoids, sterols, coumarins, and especially flavonoid aglycones and glycosides, have been identified. In particular, species from the Balkan Peninsula have been studied and found to be rich in flavonoids, with valuable antioxidant activity. In the folk medicine of the Balkan countries, Sideritis raeseri is used as an herbal tea in the treatment of inflammation, gastrointestinal disorders, and coughs and as a tonic, while extracts are used as a component of dietary supplements for anaemia...
June 25, 2016: Journal of the Science of Food and Agriculture
Ji-Xin Li, Qi-Ji Li, Yi-Fu Guan, Xun Song, Ya-Hua Liu, Jing-Jie Zhang, Wan-Fei Li, Jiang Du, Min Zhu, Jeffrey A Banas, Xiao-Nian Li, Lu-Tai Pan, Hong-Jie Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Leigong Mountain is an area in the Southwest of China where there is a high incidence rate of athlete's foot, but the Miao people, a Chinese minority who reside in this mountainous area have suffered less from this disease due to their use of the herbal medicine Isodon flavidus (Hand.-Mazz.) H. Hara. AIM OF THE STUDY: The present study is to identify the active chemical constituents responsible for antifungal effects of the folk medicine plant...
September 15, 2016: Journal of Ethnopharmacology
Song-Chol Mun, Gwan-Sim Mun
A clonal mass propagation to obtain mountainous sources of Rheum coreanum Nakai, a rare medicinal plant in Democratic People's Republic of Korea was established by rhizome tissue culture. Whole plants were selected and collected as a vigorous individual free from blights and harmful insects among wild plants of R. coreanum grown on the top of Mt. Langrim (1.540 m above the sea) situated at the northern extremity of Democratic People's Republic of Korea. Induction of the callus was determined using four organs separated from the whole plant and different plant growth regulators...
July 2016: Saudi Journal of Biological Sciences
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