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CPR Performance

Samer Tannus, Yoni Cohen, Sara Henderson, Na'ama Al Ma'mari, Tal Shavit, Weon-Young Son, Michael H Dahan
STUDY QUESTION: In IVF cycles in which the entire embryo cohort is slow growing, is it optimal to perform fresh transfer in Day 5 or to extend the culture and transfer in subsequent vitrified-warmed cycles? SUMMARY ANSWER: The outcomes depend on the degree of embryo development on Day 5. WHAT IS KNOWN ALREADY: Slow-growing blastocysts have lower implantation potential when transferred in fresh cycles. It has been suggested that embryo-endometrial asynchrony could explain this finding...
December 4, 2018: Human Reproduction
Elizabeth R Hammond, Dean E Morbeck
STUDY QUESTION: Can embryology key performance indicators (KPIs) detect shifts in laboratory performance that precede changes in clinical outcomes? SUMMARY ANSWER: Day 5 usable blastocyst rate (D5BUR) is an important embryology KPI that complements total usable blastocyst rate (TBUR) in its ability to rapidly identify adverse embryology outcomes, prior to changes in clinical outcomes. WHAT IS KNOWN ALREADY: The hypothesis that monitoring performance of an IVF laboratory using statistical process controls (SPCs) can act as an early warning signal of shifts in laboratory conditions is a hypothesis that requires validation...
December 4, 2018: Human Reproduction
Winfrida T Kaihula, Hendry R Sawe, Michael S Runyon, Brittany L Murray
BACKGROUND: Early and effective CPR increases both survival rate and post-arrest quality of life. In limited resource countries like Tanzania, there is scarce data describing the basic knowledge of CPR among Healthcare providers (HCP). This study aimed to determine the current level of knowledge on, and ability to perform, CPR among HCP at Muhimbili National Hospital (MNH). METHODS: This was a descriptive cross sectional study of a random sample of 350 HCP from all cadres and departments at MNH from October 2015 to March 2016...
December 4, 2018: BMC Health Services Research
Florian M Stumpfe, Sven Kehl, Jutta Pretscher, Friederike Baier, Christian M Bayer, Eva Schwenke, Michael O Schneider, Andreas Mayr, Ralf L Schild, Matthias Schmid, Matthias W Beckmann, Florian Faschingbauer
OBJECTIVE: To evaluate the association of short-term variation (STV) and Doppler parameters with adverse perinatal outcome in low-risk fetuses at term. METHODS: This was a retrospective study of 1008 appropriate-for-gestational age (AGA) term fetuses. Doppler measurements [umbilical artery (UA), middle cerebral artery (MCA), and cerebroplacental ratio (CPR)] and computerized CTG (cCTG) with STV analysis were performed prior to active labor (≤ 4 cm cervical dilatation) within 72 h of delivery...
December 3, 2018: Archives of Gynecology and Obstetrics
Mohammad Mahdi Zangeneh, Hasan Norouzi, Majid Mahmoudi, Hector C Goicoechea, Ali R Jalalvand
In this work, a novel impedimetric biosensor has been fabricated for detection of DNA damage induced by doxorubicin (DX). Cytochrome P450 reductase (CPR) is required for electron transfer from nicotinamide adenine dinucleotide phosphate (NADPH) to cytochrome P450 (CP450) which causes DX to undergo a one-electron reduction of the p-quinone residue to form the semiquinone radical resulting in the generation of free hydroxyl radical which causes DNA damage. After modification of bare glassy carbon electrode (GCE) with multiwalled carbon nanotubes (MWCNTs) and chitosan (Ch), CPR and CP450 were co-immobilized onto the surface of Ch/MWCNTs/GCE by cross-linking CPR, CP450 and Ch through addition of glutaraldehyde...
November 30, 2018: International Journal of Biological Macromolecules
Zhifeng Liu, Qingyu Liu, Gongfa Wu, Haigang Li, Yue Wang, Rui Chen, Cai Wen, Qin Ling, Zhengfei Yang, Wanchun Tang
Background: Utilize quantitative computed tomography (QCT) to detect and evaluate the severity of lung injury after successful cardiopulmonary resuscitation (CPR) in a porcine cardiac arrest (CA) model with different downtimes. Methods: Twenty-one male domestic pigs weighing 38±3 kg were randomized into 3 groups: the sham group (n=5), the ventricular fibrillation (VF) 5 min (VF5) group (n=8), and the VF 10 min (VF10) group (n=8). VF was induced and untreated for 5 (VF5 group) or 10 (VF10 group) min before the commencement of manual CPR...
October 2018: Quantitative Imaging in Medicine and Surgery
Sandrine Frantz, Jean Parinaud, Marion Kret, Gaelle Rocher-Escriva, Aline Papaxanthos-Roche, Hélène Creux, Lucie Chansel-Debordeaux, Antoine Bénard, Claude Hocké
STUDY QUESTION: Does endometrial scratch in women undergoing a first or second IVF/ICSI attempt improve the clinical pregnancy rate (CPR)? SUMMARY ANSWER: Endometrial scratch (ES) in women undergoing their first or second IVF/ICSI attempt does not enhance the CPR under the technical conditions of our study. WHAT IS KNOWN ALREADY: Several studies have suggested that physical scratch of the endometrium before an IVF attempt could improve embryo implantation...
November 29, 2018: Human Reproduction
Cecilia Andréll, Josef Dankiewicz, Christian Hassager, Janneke Horn, Jesper Kjærgaard, Matilde Winther-Jensen, Matt P Wise, Niklas Nielsen, Pascal Stammet, Hans Friberg
BACKGROUND: The majority of out-of-hospital cardiac arrests (OHCAs) occur at place residence, which is associated with worse outcomes in unselected prehospital populations. Our aim was to investigate whether location of arrest was associated with outcome in a selected group of initial survivors admitted to intensive care. METHODS: This is a post-hoc analysis of the Targeted Temperature Management after cardiac arrest trial (TTM trial), a multicenter controlled trial, randomizing 950 OHCA patients to an intervention of 33°C or 36°C...
November 22, 2018: Minerva Anestesiologica
N Quillinan, A L Dingman, G Deng, S Tatum, J E Orfila, A C Clevenger, J Klawitter, R J Traystman, P S Herson
Each year there are approximately 7000 out of hospital cardiac arrests in the pediatric population, with 30% resuscitation rate and a 6-10% rate of survival to hospital discharge. Survivors of cardiac arrest exhibit learning and memory deficits that are devastating during the school years. Delayed neuronal cell death occurs in the hippocampus following cardiac arrest and likely contributes to memory impairments. Circulating endogenous estrogen in young adult females has been shown to provide protection against ischemic cell death, as does chronic exogenous administration of 17β-estradiol (E2)...
November 22, 2018: Neurochemistry International
Diego Enriquez, Lorena Firenze, Josefina Fernández Díaz, Agustín Iglesias, Nicolás Falk, Pablo Pollini, Edgardo Szyld
INTRODUCTION: High-quality chest compressions (CCs) are the main component of cardiopulmonary resuscitation (CPR). Objectives. T o assess the depth of CCs during CPR using a pediatric patient manikin. A secondary objective was to explore the association between CC depth and sex, level of training, body mass index, and periodic physical training. MATERIAL AND METHODS: Prospective study with experimental observation. Pediatric residents, pediatricians, nurses, and other health care providers trained in CPR and who attended children were included...
December 1, 2018: Archivos Argentinos de Pediatría
Jean-Paul Veronese, Lee Wallis, Rachel Allgaier, Ryan Botha
Introduction: Survival rates from out-of-hospital cardiac arrest significantly improve when high-quality cardiopulmonary resuscitation (CPR) is performed. Despite sudden cardiac arrest being a leading cause of death in many parts of the world, no studies have determined the quality of CPR delivery by Emergency Medical Services (EMS) personnel in South Africa. The aim of this study was to determine the quality of CPR provision by EMS staff in a simulated setting. Methods: A descriptive study design was used to determine competency of CPR among intermediate-qualified EMS personnel...
March 2018: African Journal of Emergency Medicine Revue Africaine de la Médecine D'urgence
Yong Won Kim, Hyung Il Kim, Sung Oh Hwang, Yoon Seop Kim, Gyo Jin An, Kyoung Chul Cha
PURPOSE: Recent basic life support (BLS) guidelines recommend a 30:2 compression-to-ventilation ratio (CV2) or chest compression-only cardiopulmonary resuscitation (CC); however, there are inevitable risks of interruption of high-quality cardiopulmonary resuscitation (CPR) in CV2 and hypoxemia in CC. In this study, we compared the short-term outcomes among CC, CV2, and 30:1 CV ratio (CV1). MATERIALS AND METHODS: In total, 42 pigs were randomly assigned to CC, CV1, or CV2 groups...
December 2018: Yonsei Medical Journal
Yoshikazu Goto, Akira Funada, Yumiko Goto
AIM: The impact of prehospital physician care for out-of-hospital cardiac arrest (OHCA) on long-term neurological outcome is unclear. We aimed to determine the association between emergency medical services (EMS) physician-led cardiopulmonary resuscitation (CPR) versus paramedic-led CPR and neurologically intact survival after OHCA. METHODS: We assessed 613,251 patients using All-Japan Utstein Registry data from 2011 to 2015 retrospectively. The main outcome measure was 1-month neurologically intact survival after OHCA, defined as Cerebral Performance Category 1 or 2 (CPC 1-2)...
November 15, 2018: Resuscitation
Andrea Müller, Marco Maggiorini, Dragana Radovanovic, Paul Erne
BACKGROUND: Few studies describe recent changes in the incidence, treatment and outcome of successfully resuscitated STEMI patients after out-of-hospital cardiac arrest (OHCA) compared with non-OHCA STEMI patients. OBJECTIVE: To examine temporal trends in the incidence, therapeutic management, most serious complications, mortality rate and outcome of OHCA patients fulfilling criteria of STEMI compared with a reference group of STEMI patients without OHCA. METHODS: Analysis of registry data (AMIS Plus Registry) among STEMI patients both with and without OHCA between 1997 and 2017...
November 14, 2018: Resuscitation
Johanna van Dawen, Lina Vogt, Hanna Schröder, Rolf Rossaint, Lina Henze, Stefan K Beckers, Saša Sopka
BACKGROUND: Training lay rescuers in Basic Life Support (BLS) is essential to improve bystander cardiopulmonary resuscitation (CPR) rates; in addition, simple methods are needed to provide feedback on CPR performance. This study evaluated whether a simple observational checklist can be used by BLS instructors to adequately measure the quality of BLS performance as an alternative to other feedback devices. METHODS: The BLS performances of 152 first-year medical students (aged 21...
November 16, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Debra G Heard, Kevin H Andresen, Katie M Guthmiller, Ryan Lucas, Kennon J Heard, Audrey L Blewer, Benjamin S Abella, Lana M Gent, Comilla Sasson
STUDY OBJECTIVE: We compare 3 methods of hands-only cardiopulmonary resuscitation (CPR) education, using performance scores. A paucity of research exists on the comparative effectiveness of different types of hands-only CPR education. This study also includes a novel kiosk approach that has not previously been studied, to our knowledge. METHODS: A randomized, controlled study compared participant scores on 4 hands-only CPR outcome measures after education with a 25- to 45-minute practice-while-watching classroom session (classroom), 4-minute on-screen feedback and practice session (kiosk), and 1-minute video viewing (video only)...
November 8, 2018: Annals of Emergency Medicine
Ikuto Takeuchi, Hiroki Nagasawa, Kei Jitsuiki, Akihiko Kondo, Hiromichi Ohsaka, Youichi Yanagawa
Context/Aims: We retrospectively analyzed the characteristics of prehospital care for cardiopulmonary arrest (CPA) to identify the predictors of a good recovery (GR) among the recent changes in the management of Japanese prehospital care. Settings and Design: This study was a retrospective medical chart review. Subjects and Methods: We reviewed the transportation records written by emergency medical technicians and the characteristics of prehospital management of out-of-hospital (oh) CPA described by the Sunto-Izu Fire Department from April 2016 to March 2017...
July 2018: Journal of Emergencies, Trauma, and Shock
Rebeka Ferreira Pequeno Leite, Marinisi Sales Aragão Santos, Erlane Marques Ribeiro, André Luiz Santos Pessoa, Doris Ruthy Lewis, Célia Maria Giacheti, Luciano Pamplona de Góes Cavalcanti
OBJECTIVE: to describe the results of hearing screening performed in children with Congenital Zika Virus Syndrome (CZS) in Fortaleza, Ceará, Brazil. METHODS: this was a descriptive cross-sectional study involving children with CZS receiving health care in Fortaleza, 2016; the hearing screening tests performed were immittance audiometry, transient otoacoustic emissions (TOAE), acoustic reflexes, and cochleopalpebral reflex (CPR). RESULTS: The study included 45 children with an average age of 10 months...
November 8, 2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
Magdalena Fiolna, Vira Kostiv, Christos Anthoulakis, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVE: To investigate the performance of screening for adverse perinatal outcome by the cerebroplacental ratio (CPR) measured within 24 hours of induction of labor. METHODS: This was a prospective observational study in 1,902 singleton pregnancies undergoing induction of labor at ≥ 37 weeks' gestation. Doppler ultrasound was used to measure the pulsatility index (PI) in the umbilical artery (UA) and fetal middle cerebral artery (MCA) before induction of labor...
November 13, 2018: Ultrasound in Obstetrics & Gynecology
Sayuri Tokioka, Shinichiro Masuda, Masamitsu Shirokawa, Takashi Shibui
High-quality cardiopulmonary resuscitation (CPR) is crucial for survival from cardiac arrest. However, various chest compression-associated injuries have been reported. Internal mammary artery (IMA) injury is one of the rare complications after CPR, and most of cases include rib and sternum fractures. In this report, we describe a rare case of IMA injury without chest wall fractures after CPR. An 85-year-old man with a history of acute myocardial infarction 2 weeks prior visited to our hospital for sustained ventricular tachycardia (VT)...
2018: Case Reports in Emergency Medicine
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