keyword
MENU ▼
Read by QxMD icon Read
search

Bowel Ca

keyword
https://www.readbyqxmd.com/read/29745046/adsorption-of-soluble-immunoglobulin-type-adhesion-molecules-to-cellulose-acetate-beads
#1
Shoichi Nishise, Yuji Takeda, Hidetoshi Nara, Yasuhiko Abe, Yu Sasaki, Hironobu Asao, Yoshiyuki Ueno
Circulating levels of soluble intercellular adhesion molecule-1 (sICAM-1) and vascular adhesion molecule-1 (sVCAM-1) are elevated in patients with inflammatory bowel disease. Cellulose acetate (CA) beads are used as carriers for granulocyte and monocyte (GM) adsorptive apheresis (GMA). We investigated the effect of CA beads on sICAM-1 and sVCAM-1 plasma concentrations in vitro. Because GM adsorption to CA beads increased with a rise in the incubation temperature in our previous study, peripheral blood was incubated with and without CA beads at 5, 25, 37, or 43 °C and plasma sICAM-1 and sVCAM-1 was measured...
May 9, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29715711/effects-of-fengliao-changweikang-in-diarrhea-predominant-irritable-bowel-syndrome-rats-and-its-mechanism-involving-colonic-motility
#2
Mengdi Jia, Xiaofang Lu, Luqing Zhao, Zhengfang Wang, Shengsheng Zhang
Background/Aims: This study was designed to investigate the effect of Fengliao-Changweikang (FLCWK) in diarrhea-predominant irritable bowel syndrome (IBS-D) rats and explore its underlying mechanisms. Methods: IBS-D model rats were induced by neonatal maternal separation (NMS) combined with restraint stress (RS). In in vivo experiments, the model rats were randomly divided into 5 groups: NMS + RS, FLCWK (low dose, middle dose, and high dose), and pinaverium bromide...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29685047/long-term-results-of-linaclotide-in-the-treatment-of-constipation-type-irritable-bowel-syndrome
#3
Fernando Geijo Martínez, Ana Sánchez Garrido, Héctor Marcos Prieto, Concepción Piñeiro Pérez, Ana Beatriz Prieto Bermejo, Alberto Álvarez Delgado, Antonio Velasco Guardado, Antonio Rodríguez Pérez
BACKGROUND: constipation-predominant irritable bowel syndrome (C-IBS) is a prevalent, complex and multifactorial disorder that represents a challenge in terms of diagnosis and therapeutic management. OBJECTIVE: to evaluate the effectiveness, safety and treatment satisfaction of linaclotide in C-IBS patients. METHODS: prospective, single-center and observational study conducted in patients diagnosed with C-IBS. The patients were treated with linaclotide (Constella®, Allergan Inc...
April 24, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29683235/a-study-of-clinicopathologic-factors-as-indicators-for-early-prediction-of-suboptimal-debulking-surgery-after-neoadjuvant-chemotherapy-in-advanced-ovarian-cancer
#4
Joo-Hyuk Son, Kyoungjin Chang, Tae-Wook Kong, Jiheum Paek, Suk-Joon Chang, Hee-Sug Ryu
AIM: This study aimed to evaluate early clinicopathologic factors predicting gross residual disease after neoadjuvant chemotherapy in patients with advanced epithelial ovarian cancer. METHODS: We analyzed clinicopathologic data of 68 patients with ovarian cancer who were treated with neoadjuvant chemotherapy followed by interval debulking surgery (NAC-IDS) between March 2006 and December 2016. All the patients received three cycles of NAC followed IDS. We evaluated all possible clinicopathologic characteristics, including reduction rates of serum CA-125 after each NAC and seven initial abdominopelvic computed tomography (CT) findings related to disease severity...
April 23, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29455011/hybrid-retrograde-celiac-artery-stenting-for-acute-mesenteric-ischemia-after-gastric-surgery
#5
Duarte Rego, Paulo Almeida, Paulo Soares, Rui Almeida
BACKGROUND: Celiac artery (CA) occlusions/stenosis is infrequently associated with liver ischemia due to its unique vascularization, where portal vein provides about 75% of liver's perfusion. Collateral flow from gastroduodenal artery also provides, in most cases, enough blood supply to prevent ischemic hepatitis. In cases where these collateral pathways are compromised, severe liver ischemia can occur. METHODS: We present a case of acute mesenteric ischemia following gastric surgery that was treated with a hybrid retrograde CA stenting...
May 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29451468/health-care-resource-use-and-costs-pre-and-post-treatment-initiation-with-linaclotide-retrospective-analyses-of-a-u-s-insured-population
#6
Douglas Ca Taylor, Jessica L Abel, Tim Bancroft, Paul Buzinec, Alyssa Goolsby Hunter, Robyn T Carson, Carolyn Martin
As expected, pharmacy costs increased with the introduction of this new treatment in a market dominated by over-the-counter and generic treatments. On the other hand, outpatient GI-related and irritable bowel disease health care resource use and costs substantially decreased among commercial and Medicare patients following linaclotide treatment initiation.
February 2018: Managed Care
https://www.readbyqxmd.com/read/29416804/clinicopathological-features-and-prognosis-of-intestinal-hepatoid-adenocarcinoma-evaluation-of-a-pooled-case-series
#7
Xiangyu Zeng, Peng Zhang, Hua Xiao, Xiuli Wu, Weizhen Liu, Jun He, Jinbo Gao, Guobin Wang, Xiaoming Shuai, Kaixiong Tao
Backgroud: Intestinal hepatoid adenocarcinoma (IHA) is a very rare and unique intestinal malignancy. Due to the lack of case series specifically pertaining to IHA, the clinicopathological features and prognosis of it remain unclear. Results: Of the 42 patients enrolled in this study, 30 (71.4%) were male. Twenty-one cases (50.0%) were located in the colon. Eight cases (19.0%) had accompanying inflammatory bowel disease (IBD). Elevated serum alpha-fetoprotein (AFP) was detected for most patients (25/33, 84...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29380107/prognostic-role-of-mesenteric-lymph-nodes-involvement-in-patients-undergoing-posterior-pelvic-exenteration-during-radical-or-supra-radical-surgery-for-advanced-ovarian-cancer
#8
Roberto Berretta, Vito Andrea Capozzi, Giulio Sozzi, Lavinia Volpi, Valentina Ceni, Mauro Melpignano, Giovanna Giordano, Federico Marchesi, Michela Monica, Maurizio Di Serio, Matteo Riccò, Marcello Ceccaroni
PURPOSE: The aim of this retrospective study is to analyze the prognostic role and the practical implication of mesenteric lymph nodes (MLN) involvements in advanced ovarian cancer (AOC). METHODS: A total of 429 patients with AOC underwent surgery between December 2007 and May 2017. We included in the study 83 patients who had primary (PDS) or interval debulking surgery (IDS) for AOC with bowel resection. Numbers, characteristics and surgical implication of MLN involvement were considered...
April 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29360690/predicting-6-and-12-month-risk-of-mortality-in-patients-with-platinum-resistant-advanced-stage-ovarian-cancer-prognostic-model-to-guide-palliative-care-referrals
#9
Jonathan Foote, Micael Lopez-Acevedo, Gregory Samsa, Paula S Lee, Arif H Kamal, Angeles Alvarez Secord, Laura J Havrilesky
OBJECTIVE: Predictive models are increasingly being used in clinical practice. The aim of the study was to develop a predictive model to identify patients with platinum-resistant ovarian cancer with a prognosis of less than 6 to 12 months who may benefit from immediate referral to hospice care. METHODS: A retrospective chart review identified patients with platinum-resistant epithelial ovarian cancer who were treated at our institution between 2000 and 2011. A predictive model for survival was constructed based on the time from development of platinum resistance to death...
February 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29335251/goblet-cell-carcinomas-of-the-appendix-rare-but-aggressive-neoplasms-with-challenging-management
#10
Ashley K Clift, Oskar Kornasiewicz, Panagiotis Drymousis, Omar Faiz, Harpreet S Wasan, James M Kinross, Thomas Cecil, Andrea Frilling
Goblet cell carcinomas (GCC) are a rare, aggressive sub-type of appendiceal tumours with neuroendocrine features, and controversy exists with regards to therapeutic strategy. We undertook a retrospective review of GCC patients surgically treated at two tertiary referral centres. Clinical and histopathological data were extracted from a prospectively maintained database. Survival analyses utilised Kaplan-Meier methodology. Twenty-one patients were identified (9 females). Median age at diagnosis was 55 years (range 32-77)...
February 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29276734/stress-the-gut-brain-axis-regulation-by-the-microbiome
#11
REVIEW
Jane A Foster, Linda Rinaman, John F Cryan
The importance of the gut-brain axis in regulating stress-related responses has long been appreciated. More recently, the microbiota has emerged as a key player in the control of this axis, especially during conditions of stress provoked by real or perceived homeostatic challenge. Diet is one of the most important modifying factors of the microbiota-gut-brain axis. The routes of communication between the microbiota and brain are slowly being unravelled, and include the vagus nerve, gut hormone signaling, the immune system, tryptophan metabolism, and microbial metabolites such as short chain fatty acids...
December 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/29247810/surgical-revascularization-of-the-celiac-artery-for-persistent-intestinal-ischemia-in-short-bowel-syndrome
#12
Arnaud Roussel, Alexandre Nuzzo, Quentin Pellenc, Yves Castier, Romain De Blic, Pierre Cerceau, Célia Boulitrop, Mathieu Coblence, Sonia Aguir, Pierre Mordant, Léon Maggiori, Audrey Huguet, Annie Sibert, Francisca Joly, Olivier Corcos
BACKGROUND AND OBJECTIVES: Without prompt superior mesenteric artery (SMA) revascularization, acute mesenteric ischemia (AMI) frequently leads to death or short bowel syndrome (SBS). In SBS patients, persistent or chronic intestinal ischemia (PII) of the remnant bowel can lead to recurrences of AMI. Since SMA revascularization is sometimes unfeasible, celiac artery (CA) revascularization may improve blood supply to the remnant bowel. The aim of this study was to describe and to assess our experience of the CA revascularization in case of SMA occlusion unsuitable for revascularization in the setting of PII in SBS patients...
January 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29245257/endometrial-stromal-sarcoma-in-combination-with-mixed-type-endometrial-carcinomas-a-case-report-and-literature-review
#13
REVIEW
Xiao-Xin Xiu, Hua-Li Wang, Lv Yun-Yi, Kong Fan-Dou, Hou Jin-Ping
RATIONALE: Endometrial stromal sarcoma (ESS) is rare, representing only approximately 0.2% of all uterine malignancies. Mixed type endometrial carcinomas (MT-ECs) are rare tumors with both type I and II features, and are difficult to diagnose. Cases of ESS and MT-ECs coexisting in the same patient are extremely rare. This study aimed to describe a case of ESS in combination with MT-ECs in a 47-year-old premenopausal woman. PATIENT CONCERNS: A woman presented to the hospital complaining of occasional abdominal pain and had high tumor markers: cancer antigen (CA) 19-9 (263...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29203996/metachronous-synchronous-sternal-and-colonic-metastasis-with-asymptomatic-colo-colic-fistula-from-carcinoma-ovary-rare-presentation-of-ovarian-cancer
#14
Srinivas K G, Abid Ali Mirza, Shivananda Swamy, Amarendra S, Gopinath Ks
Ovarian cancer is one of the most common gynecological cancers worldwide. It is the third leading cause of cancer among women in India. Metastatic disease to the visceral organs from ovarian cancer occurs as a terminal event in the natural history of the disease. In particular, spread to the bone and large bowel is infrequently described. The risk of distant metastasis increases in a recurrent setting. We describe a case of a 77-year-old lady, who was diagnosed for ovarian carcinoma in 2007 and underwent primary cytoreductive surgery, stage IIIc...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29146096/ten-year-review-of-isolated-spontaneous-mesenteric-arterial-dissections
#15
Courtney E Morgan, Neel A Mansukhani, Mark K Eskandari, Heron E Rodriguez
OBJECTIVE: Isolated spontaneous dissection of the superior mesenteric artery (SMA) and celiac artery (CA) remains a rare condition; however, it has been increasingly noted incidentally on diagnostic imaging. The purpose of this study was to examine the natural history and outcomes of patients presenting with isolated spontaneous mesenteric artery dissection (SMAD). We hypothesized that most SMADs can be treated nonoperatively. METHODS: This was a single-center retrospective review of patients presenting with the diagnosis of SMAD between 2006 and 2016...
April 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29100591/outcomes-of-complicated-appendicitis-is-conservative-management-as-smooth-as-it-seems
#16
Katelyn A Young, Nina M Neuhaus, Marcus Fluck, Joseph A Blansfield, Marie A Hunsinger, Mohsen M Shabahang, Denise M Torres, Kenneth A Widom, Jeffrey L Wild
BACKGROUND: This study characterized the failure rate of non-operative management (NOM) for complicated appendicitis (CA; perforation, abscess, phlegmon), and compared outcomes among patients undergoing acute appendectomy (AA), elective interval appendectomy (EIA), and unplanned appendectomy after failing to improve with NOM. METHODS: Adults treated at one facility between 2007 and 2014 were retrospectively studied. RESULTS: Ninety-five patients presented with CA...
April 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29027719/glioplasticity-in-irritable-bowel-syndrome
#17
N L Lilli, L Quénéhervé, S Haddara, C Brochard, P Aubert, M Rolli-Derkinderen, T Durand, P Naveilhan, J-B Hardouin, R De Giorgio, G Barbara, S Bruley des Varannes, E Coron, M Neunlist
BACKGROUND: Growing evidence indicates a wide array of cellular remodeling in the mucosal microenvironment during irritable bowel syndrome (IBS), which possibly contributes to pathophysiology and symptom generation. Here, we investigated whether enteric glial cells (EGC) may be altered, and which factors/mechanisms lead to these changes. METHODS: Colonic mucosal biopsies of IBS patients (13 IBS-Constipation [IBS-C]; 10 IBS-Diarrhea [IBS-D]; 11 IBS-Mixed [IBS-M]) and 24 healthy controls (HC) were analyzed...
April 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28887507/carnosic-acid-prevents-dextran-sulfate-sodium-induced-acute-colitis-associated-with-the-regulation-of-the-keap1-nrf2-pathway
#18
Neng Yang, Zongling Xia, Naiyuan Shao, Bowen Li, Lian Xue, Ya Peng, Feng Zhi, Yilin Yang
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBDs) with high prevalence in humans. Carnosic acid (CA) has been reported to possess antioxidative properties; however, its role in IBDs has not been determined. In the present study, we found that CA significantly prevented the loss of body weight and shortening of colon length in acute colitis induced by dextran sodium sulfate (DSS). Pronounced infiltration of immune cells and a loss of crypt architecture and goblet cells were ameliorated by CA...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28756376/obturator-hernia-a-rare-cause-of-bowel-obstruction
#19
Cã Tia Carreira Rito, Josà Travassos, Joana Patrà Cio, Ana Luisa Duarte
An obturator hernia is a rare condition and an unusual cause of intestinal obstruction. With a challenging diagnosis, it has one of the highest mortality rates of all abdominal wall hernias. The authors present a case of an elderly woman with bowel obstruction secondary to an incarcerated obturator hernia. An 80-year-old woman presented at the emergency room with complaints for the last 2 days of nausea, vomiting, constipation and lower right abdominal pain that radiated down to the right medial thigh. Abdominal tenderness to deep palpation of the right iliac fossa and mildly distention were noted...
July 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28707149/long-term-quality-of-life-and-outcomes-following-robotic-assisted-tapp-inguinal-hernia-repair
#20
Andrew Iraniha, Joshua Peloquin
Laparoscopic TAPP inguinal hernia repair is an established alternative to open hernia repair, which offers equivalent outcomes with less postoperative pain and faster recovery. Unfortunately, it remains technically challenging, requiring advanced laparoscopic skills which have limited its popularity among surgeons. The robotic platform has the potential to overcome these challenges. The objective of this study was to examine the long-term quality of life and outcomes following robotic assisted TAPP inguinal hernia repair, since these data have not been reported up to now...
July 13, 2017: Journal of Robotic Surgery
keyword
keyword
16536
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"