Liqing Peng, Hao Li, Haoyuan Deng, Tianze Gao, Runmeng Li, Ziheng Xu, Qinyu Tian, Tianyuan Zhao, Jianwei Li, Yongkang Yang, Chao Wang, Shuyun Liu, Quanyi Guo
BACKGROUND: The utilization of decellularized extracellular matrix has gained considerable attention across numerous areas in regenerative research. Of particular interest is the human articular cartilage-derived extracellular matrix (hACECM), which presents as a promising facilitator for cartilage regeneration. Concurrently, the microfracture (MF) technique, a well-established marrow stimulation method, has proven efficacious in the repair of cartilage defects. However, as of the current literature review, no investigations have explored the potential of a combined application of hACECM and the microfracture technique in the repair of cartilage defects within a sheep model...
January 2024: Journal of Orthopaedic Translation