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cyanoacrylate vein ablation

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https://www.readbyqxmd.com/read/30403154/comparison-of-cyanoacrylate-closure-and-radiofrequency-ablation-for-the-treatment-of-incompetent-great-saphenous-veins-36-month-outcomes-of-the-veclose-randomized-controlled-trial
#1
Nick Morrison, Raghu Kolluri, Michael Vasquez, Monte Madsen, Andrew Jones, Kathleen Gibson
OBJECTIVE: To evaluate the 36-month efficacy and safety of cyanoacrylate closure for the treatment of incompetent great saphenous veins in comparison with radiofrequency ablation. METHODS: In this multicenter, prospective, randomized controlled trial, 222 symptomatic subjects with incompetent great saphenous veins were assigned to either cyanoacrylate closure or radiofrequency ablation. The primary endpoint, complete closure of the target great saphenous vein, was determined using duplex ultrasound examination starting from three-month visit...
November 7, 2018: Phlebology
https://www.readbyqxmd.com/read/30263121/cost-effectiveness-analysis-of-five-procedures-for-great-saphenous-vein-reflux-in-a-norwegian-healthcare-setting-or-societal-setting
#2
Eivind Inderhaug, Carl-Henrik Schelp, Inge Glambek, Ivar S Kristiansen
Objective: The aim of this work was to estimate cost-effectiveness of five common procedures for varicose vein surgery ( high ligation and stripping, radiofrequency ablation, endovenous laser ablation, steam vein sclerosis and cyanoacrylate glue ) in a Norwegian setting from both a societal and a healthcare payer perspective. Design: Cost-effectiveness analysis using decision tree modelling. Methods: A structured literature search was conducted to estimate the clinical effectiveness and the rate of complications in the five methods...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/30238444/a-randomized-trial-of-early-endovenous-ablation-in-venous-ulceration-a-critical-appraisal
#3
K T Weiß, F Zeman, S Schreml
Manjit S. Gohel et al. (N Engl J Med 2018; 378: 2105-2114) aimed to compare early endovenous ablation vs. deferred endovenous ablation of superficial venous reflux regarding time to healing of venous leg ulcers, rate of healing at 24 weeks, recurrence rate, ulcer-free time, and health-related quality of life. SETTING AND DESIGN: This multicentre, parallel-group (ratio 1:1), randomized controlled trial was conducted in a vascular surgery department setting at 20 participating centres across the United Kingdom...
September 20, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/30227791/need-for-adjunctive-procedures-following-cyanoacrylate-closure-of-incompetent-great-small-and-accessory-saphenous-veins-without-the-use-of-postprocedure-compression-three-month-data-from-a-postmarket-evaluation-of-the-venaseal-system-the-waves-study
#4
Kathleen Gibson, Renee Minjarez, Krissa Gunderson, Brian Ferris
Purpose Studies examining cyanoacrylate closure of saphenous veins with the VenaSeal™ System have not allowed concomitant procedures for tributaries at the time of the index procedure. Outside of clinical trials, however, concomitant procedures are frequently performed in conjunction with endovenous ablation. We report on the frequency of need for saphenous tributary treatment three months after cyanoacrylate closure of the treatment of great saphenous vein, small saphenous vein, and/or accessory saphenous vein...
September 18, 2018: Phlebology
https://www.readbyqxmd.com/read/30217712/clinical-features-and-management-of-phlebitis-like-abnormal-reaction-after-cyanoacrylate-closure-for-the-treatment-of-incompetent-saphenous-veins
#5
Insoo Park, Min Ho Jeong, Chan Jin Park, Woo Il Park, Dong Wook Park, Jin Hyun Joh
BACKGROUND: Cyanoacrylate closure for the treatment of incompetent saphenous veins does not cause thermal damage and demonstrates satisfactory outcomes with rapid recovery. However, the characteristics of phlebitis-like abnormal reaction (PLAR), the most common adverse event after cyanoacrylate closure, have not been clarified. Moreover, it differs from typical phlebitis after thermal ablation. The objective of our study is to investigate the clinical features of PLAR after cyanoacrylate closure and to report its management...
September 11, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30114987/comparison-of-cyanoacrylate-embolization-and-radiofrequency-ablation-for-the-treatment-of-varicose-veins
#6
Gary K Yang, Marina Parapini, Joel Gagnon, Jerry C Chen
Objective To review clinical outcomes of varicose vein patients treated with cyanoacrylate embolization and radiofrequency ablation at our institution. Methods A retrospective review of patients who underwent cyanoacrylate embolization and radiofrequency ablation during a three-year period. Patient records were reviewed to assess demographics, location and severity of disease, treatment details and outcome at short- and mid-term follow-ups. Outcome parameters included treatment success and complications. Results Between January 2014 and December 2016, 335 patients with 476 veins were treated with either cyanoacrylate embolization (n = 148) or radiofrequency ablation (n = 328) at the Vancouver General Hospital Vascular Surgery Vein Clinic...
August 16, 2018: Phlebology
https://www.readbyqxmd.com/read/30098668/cost-effectiveness-of-current-and-emerging-treatments-of-varicose-veins
#7
REVIEW
David Epstein, Sarah Onida, Roshan Bootun, Marta Ortega-Ortega, Alun H Davies
OBJECTIVES: To analyze the cost-effectiveness of current technologies (conservative care [CONS], high-ligation surgery [HL/S], ultrasound-guided foam sclerotherapy [UGFS], endovenous laser ablation [EVLA], and radiofrequency ablation [RFA]) and emerging technologies (mechanochemical ablation [MOCA] and cyanoacrylate glue occlusion [CAE]) for treatment of varicose veins over 5 years. METHODS: A Markov decision model was constructed. Effectiveness was measured by re-intervention on the truncal vein, re-treatment of residual varicosities, and quality-adjusted life-years (QALYs) over 5 years...
August 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30086774/mechanochemical-ablation-versus-cyanoacrylate-adhesive-for-the-treatment-of-varicose-veins-study-protocol-for-a-randomised-controlled-trial
#8
Amjad Belramman, Roshan Bootun, Tjun Yip Tang, Tristan R A Lane, Alun H Davies
BACKGROUND: Thermal ablation techniques have become the first-line treatment of truncal veins in the management of chronic venous disease (CVD). Despite excellent outcomes, these methods are often associated with pain; generally due to their use of heat and the necessity of fluid infiltration around the vein. More recently, novel non-thermal techniques, such as mechanochemical ablation (MOCA) and cyanoacrylate adhesive (CAE) have been developed to overcome these unwelcome effects. So far, the novel techniques have been found to have similar efficacy to thermal methods, yet no direct comparisons between the non-thermal treatment techniques have been conducted to date, giving rise to this study...
August 7, 2018: Trials
https://www.readbyqxmd.com/read/30042039/a-randomised-clinical-trial-comparing-n-butyl-cyanoacrylate-radiofrequency-ablation-and-endovenous-laser-ablation-for-the-treatment-of-superficial-venous-incompetence-two-year-follow-up-results
#9
Erdinc Eroglu, Alptekin Yasim
OBJECTIVE: To compare early and two year results for N-butyl cyanoacrylate (NBCA), radiofrequency ablation (RFA), and endovenous laser ablation (EVLA) in the treatment of varicose veins. METHODS: This was a randomised clinical trial. Five hundred and twenty five patients were blindly randomised into NBCA, RFA, and EVLT groups (175 patients to each group; block randomisation using sealed envelopes). Four hundred and fifty six patients were monitored for 2 years (ultrasound at 2 days, and 6, 12, and 24 months)...
July 2, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29914814/twenty-four-month-results-from-a-randomized-trial-of-cyanoacrylate-closure-versus-radiofrequency-ablation-for-the-treatment-of-incompetent-great-saphenous-veins
#10
Kathleen Gibson, Nick Morrison, Raghu Kolluri, Michael Vasquez, Robert Weiss, Daniel Cher, Monte Madsen, Andrew Jones
OBJECTIVE: We previously reported 3-month and 12-month occlusion rates after treatment of clinically symptomatic saphenous vein reflux with either cyanoacrylate closure (CAC) using the VenaSeal Closure System (Medtronic, Dublin, Ireland) or radiofrequency ablation (RFA) in a randomized, multicenter, clinical trial, VenaSeal Sapheon Closure System vs Radiofrequency Ablation for Incompetent Great Saphenous Veins (VeClose). Herein we report the 24-month follow-up results of the VeClose trial...
September 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29671660/saphenous-vein-ablation-with-a-new-cyanoacrylate-glue-device-a-systematic-review-on-1000-cases
#11
Daniele Bissacco, Silvia Stegher, Fabio Massimo Calliari, Marco Piercarlo Viani
BACKGROUND: To review published evidence regarding an n-butyl-cyanoacrylate (NBCA) injection device for great (GSV) and small (SSV) saphenous vein incompetence in terms of occlusion rate, postoperative complications and quality of life improvement. MATERIAL AND METHODS: International bibliographic databases (PubMed, EMBASE, Scopus) were searched to identify possible target articles. The only inclusion criterion was the use of the Variclose® system (Biolas, Ankara, Turkey) for superficial vein insufficiency...
April 19, 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29642798/a-retrospective-study-of-a-new-n-butyl-2-cyanoacrylate-glue-ablation-catheter-incorporated-with-application-guiding-light-for-the-treatment-of-venous-insufficiency-twelve-month-results
#12
Turhan Yavuz, Altay Nihat Acar, Huseyin Aydın, Evren Ekingen
Objective This study aims to present the early results of a retrospective study of the use of novel n-butyl-2-cyanoacrylate (VenaBlock)-based nontumescent endovenous ablation with a guiding light for the treatment of patients with varicose veins. Methods Patients with lower limb venous insufficiency were treated with n-butyl-2-cyanoacrylate (VenaBlock Venous Closure System) between April 2016 and July 2016. The study enrolled adults aged 21-70 years with symptomatic moderate to severe varicosities (C2-C4b) and great saphenous vein reflux lasting longer than 0...
October 2018: Vascular
https://www.readbyqxmd.com/read/29037363/a-systematic-review-and-meta-analysis-of-two-novel-techniques-of-nonthermal-endovenous-ablation-of-the-great-saphenous-vein
#13
REVIEW
Cornelis G Vos, Çağdaş Ünlü, Jan Bosma, Clarissa J van Vlijmen, A Jorianne de Nie, Michiel A Schreve
BACKGROUND: Endothermal treatment of the great saphenous vein (GSV) has become the first-line treatment for superficial venous reflux. Nonthermal ablation has potential benefits for acceptability by patients and decreased risk of nerve injury. We performed a systematic review and meta-analysis to evaluate the efficacy of mechanochemical endovenous ablation (MOCA) and cyanoacrylate vein ablation (CAVA) for GSV incompetence. METHODS: MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, and Cochrane databases were searched for papers published between January 1966 and December 2016...
November 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28893152/a-new-percutaneous-technique-n-butyl-cyanoacrylate-adhesive-for-the-treatment-of-giant-saphenous-vein-insufficiency
#14
Mehmet Senel Bademci, Kaptanıderya Tayfur, Gökhan Ocakoglu, Serkan Yazman, Muhammet Akyüz, Haydar Yasa
Background We have made a retrospective evaluation of the results of the cyanoacrylate ablation technique which has recently started to be used in the treatment of giant saphenous vein insufficiency today and in which tumescent anesthesia is not required. Methods Giant saphenous vein was treated in 50 patients between September 2015 and September 2016 by using endovenous cyanoacrylate ablation. In the procedure, tumescent anesthesia and varsity socks were not used. Control duplex ultrasound evaluation was performed in the post-procedural 1st, 6th and 12th months...
April 2018: Vascular
https://www.readbyqxmd.com/read/28892412/expert-review-on-the-venaseal%C3%A2-system-for-endovenous-cyano-acrylate-adhesive-ablation-of-incompetent-saphenous-trunks-in-patients-with-varicose-veins
#15
REVIEW
Yee Lai Lam, Marianne De Maeseneer, James Lawson, Gert Jan De Borst, Doeke Boersma
The treatment of incompetent truncal veins has been innovated by the introduction of minimally invasive non-thermal non-tumescent (NTNT) techniques. One of these consists of the use of cyanoacrylate glue to occlude the vein lumen by means of the VenaSeal device. Areas covered: This expert-review aims to evaluate NTNT ablation of incompetent saphenous trunks using the VenaSeal device. Expert commentary: Cyanoacrylate adhesive embolization of incompetent truncal veins using the VenaSeal device is a safe and efficacious innovative technique...
October 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28669248/mid-term-results-in-the-treatment-of-varicose-veins-with-n-butyl-cyanoacrylate
#16
Erdinc Eroglu, Alptekin Yasim, Murat Ari, Hasan Ekerbicer, Aydemir Kocarslan, Mehmet Kabalci, Mehmet Acıpayam
Aim To present mid-term results of patients with varicose veins treated with N-butyl cyanoacrylate (VariClose®), a nontumescent endovenous ablation technique. Patients and method Endovenous ablation was performed on 180 patients with saphenous vein incompetence between May and October 2014. One hundred sixty-eight subjects capable of being followed-up for 30 months were included. Patients' pre- and postoperative data were recorded. Results Procedures were performed on the great saphenous vein in 159 patients and on the small saphenous vein in nine patients...
December 2017: Phlebology
https://www.readbyqxmd.com/read/28411697/veclose-trial-12-month-outcomes-of-cyanoacrylate-closure-versus-radiofrequency-ablation-for-incompetent-great-saphenous-veins
#17
RANDOMIZED CONTROLLED TRIAL
Nick Morrison, Kathleen Gibson, Michael Vasquez, Robert Weiss, Daniel Cher, Monte Madsen, Andrew Jones
OBJECTIVE: Endovenous cyanoacrylate closure (CAC) is a new U.S. Food and Drug Administration-approved therapy for treatment of clinically symptomatic venous reflux in saphenous veins. The device is indicated for the permanent closure of lower extremity superficial truncal veins, such as the great saphenous vein (GSV). Early results from a randomized trial of CAC have been reported previously. Herein we report 1-year outcomes. METHODS: There were 222 subjects with symptomatic GSV incompetence randomly assigned to receive either CAC (n = 108) or radiofrequency ablation (RFA; n = 114)...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214489/ablation-of-the-great-saphenous-vein-with-nontumescent-n-butyl-cyanoacrylate-versus-endovenous-laser-therapy
#18
COMPARATIVE STUDY
İsmail Koramaz, Helin El Kılıç, Fatih Gökalp, Macit Bitargil, Nilüfer Bektaş, Ersoy Engin, Mehmet Taşkın Egici, Ahmet Kürşat Bozkurt
OBJECTIVE: The endovenous application of n-butyl cyanoacrylate (NBCA) is a new nontumescent ablation technique for the treatment of venous insufficiency. The aim of this study was to retrospectively compare an NBCA-based ablation method with endovenous laser ablation (EVLA) for the management of incompetent great saphenous veins. METHODS: Between May 2013 and August 2014, there were 339 patients with incompetent varicose veins who were treated with either the endovenous application of NBCA (VariClose Vein Sealing System [VVSS]; Biolas, Ankara, Turkey) or EVLA...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27981883/varicose-vein-therapy-and-nerve-lesions
#19
Tobias Hirsch
Treating varicose veins using endovenous thermal techniques - especially laser and radio frequency ablation - has emerged as an effective alternative to open surgery with stripping and high ligation. Even though these methods are very gentle and patient-friendly, they are nevertheless accompanied by risks and side effects. Compared to open surgical therapy, the risk of damage to peripheral and motor nerves is reduced; however, it still exists as a result of heat exposure and tumescent anaesthesia. Non-thermal methods that can be applied without tumescent anaesthesia have been introduced to the market...
March 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27638993/roll-in-phase-analysis-of-clinical-study-of-cyanoacrylate-closure-for-incompetent-great-saphenous-veins
#20
RANDOMIZED CONTROLLED TRIAL
Raghu Kolluri, Kathleen Gibson, Daniel Cher, Monte Madsen, Robert Weiss, Nick Morrison
OBJECTIVE: Cyanoacrylate closure (CAC) was shown in the recently published VenaSeal Sapheon Closure System vs Radiofrequency Ablation for Incompetent Great Saphenous Veins (VeClose) randomized clinical study to be an effective and noninferior option (in terms of both safety and effectiveness) to radiofrequency ablation (RFA) in the treatment of incompetent great saphenous veins. The objectives of this analysis were to report the efficacy and safety outcomes of the VeClose roll-in (training) group treated with CAC by physicians who had received device use training but had no prior treatment experience with the technique and to compare the outcomes with those from the randomized RFA and CAC groups...
October 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
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