Read by QxMD icon Read


Joshua D Moss, Adam Oesterle, Michael Raiman, Erin E Flatley, Andrew D Beaser, Valluvan Jeevanandam, Liviu Klein, Takeyoshi Ota, Georg Wieselthaler, Nir Uriel, Roderick Tung
INTRODUCTION: Ventricular arrhythmias (VA) after left ventricular assist device (LVAD) placement are associated with increased morbidity and mortality. We sought to assess epicardial voltage characteristics at the time of LVAD implantation and investigate relationships between scar burden and post-implant VA. METHODS AND RESULTS: Consecutive patients underwent open-chest epicardial electroanatomic mapping immediately prior to LVAD implantation. Areas of low voltage and sites with local abnormal potentials were identified...
December 5, 2018: Journal of Cardiovascular Electrophysiology
Cory J Rice, Sung-Min Cho, Lucy Q Zhang, Catherine Hassett, Randall C Starling, Ken Uchino
BACKGROUND: Ischemic and hemorrhagic strokes are frequent complications among those with left ventricular assist device (LVAD). Scarce data exist regarding the prevalence of acute large vessel occlusion (LVO) and treatment of acute ischemic stroke (AIS) in this setting. METHODS: We reviewed prospectively collected data of LVAD patient registry from a single, tertiary center from October 2004 to November 2016. Among those with AIS complications, patients were divided into early stroke (during implantation hospitalization) and late stroke (post-discharge) groups, and neuroimaging was reviewed and data on acute stroke therapy were collected...
December 4, 2018: Cerebrovascular Diseases
Kaiyun Gu, Zhe Zhang, Yu Chang, Bin Gao, Feng Wan
BACKGROUND: Hemodynamic characteristics of the interaction influence among support level and model of LVAD, and coupling β-blocker has not been reported. METHODS: In this study, the effect of support level and model of LVAD on cardiovascular hemodynamic characteristics is investigated. In addition, the effect of β-blocker on unloading with LVAD is analyzed to elucidate the mechanism of LVAD coupling β-blocker. A multi-scale model from cell level to system level is proposed...
December 3, 2018: Biomedical Engineering Online
Sung-Min Cho, Catherine Hassett, Cory J Rice, Randall Starling, Irene Katzan, Ken Uchino
Acute ischemic stroke (AIS) is a major complication in left ventricular assist device (LVAD) population. A better understanding of clinical risk factors associated with AIS may help mitigate risk of stroke. We reviewed prospectively collected data of 477 LVAD patients from a tertiary center from October 1, 2004 to December 31, 2016. Supplemental data abstraction was performed on patients with AIS. Fifty-seven (12%) developed 61 AIS. Of 61, 17 (28%) AIS occurred perioperatively. The median time from implant to perioperative AIS was 5 days (interquartile range: 3-9)...
November 28, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Brendan P Chou, Harveen K Lamba, Faisal H Cheema, Andrew B Civitello, Reynolds M Delgado, Leo Simpson, Ajith P Nair, Selby Oberton, Ziad A Taimeh, Todd K Rosengart, O H Frazier, Jeffrey A Morgan
Implantable continuous-flow left ventricular assist devices (CF-LVADs) are used for long-term LV support in bridging patients to heart transplantation or as destination therapy. With prolonged support times, some patients will have repeat complications necessitating multiple device exchanges. To elucidate the safety and efficacy of repeat device exchange, we retrospectively reviewed data from 25 patients who underwent two or more CF-LVAD implantations between July 2005 and August 2017. Indications for exchange were thrombus/hemolysis (n = 8, 32%), electromechanical device malfunction (n = 14, 56%), and infection (n = 3, 12%)...
November 28, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Sugat Wagle, Baqir A Lakhani, Christopher T Salerno, Ashwin K Ravichandran, Sunit-Preet Chaudhry
The Dor procedure was historically used to restore the geometry of the heart in a patient with a left ventricular (LV) aneurysm via reduction and reshaping of the LV with an aneurysmectomy. Unfortunately, morbidity and mortality remain high with this procedure, with many patients little to no recovery of their ejection fraction while developing severe diastolic failure, often requiring further support; however, the natural history of these patients remains largely unknown. Heart transplant has long been considered the most durable of treatment for patients with end-stage heart failure (HF), but because of the scarcity of donor hearts, the implantation of left ventricular assist devices (LVAD) for mechanical circulatory support has also proven to be an essential tool in the treatment of the advanced heart failure patient...
November 21, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Rachel Sara Bercovitz
There is a delicate balance between bleeding and clotting in patients on circuits such as ventricular assist devices or extracorporeal membrane oxygenation. Traditional coagulation tests, prothrombin time, activated partial thromboplastin time, and anti-factor Xa levels, are used to monitor patients on these devices. However, turnaround times and inability to assess global hemostasis, including platelets and fibrinogen have contributed to a recognition that faster, accurate, and more informative coagulation tests are needed...
November 30, 2018: Hematology—the Education Program of the American Society of Hematology
Jan Knierim, Roland Heck, Marina Pieri, Felix Schoenrath, Sajjad Soltani, Philipp Stawowy, Stephan Dreysse, Julia Stein, Marcus Müller, Johanna Mulzer, Michael Dandel, Volkmar Falk, Thomas Krabatsch, Evgenij Potapov
BACKGROUND: In this retrospective analysis we evaluated a standardized echocardiographic assessment and an invasive technique for patient selection for successful continuous-flow left ventricular assist device (CF-LVAD) explantation. METHODS: Inclusion criteria for LVAD recovery assessment were: clinically stable condition; LVAD support for >6 months; physical activity; normal echocardiography findings; and no more than mild valvular disease and aortic valve opening...
November 15, 2018: Journal of Heart and Lung Transplantation
Utkarsh Kohli, Karen L Pumphrey, Aziez Ahmed, Srikant Das
A 13 kg, 20 month-old, Caucasian girl, presented with cardiomyopathy, biventricular dysfunction and pre-excitation on electrocardiogram. She had normal intracardiac anatomy with severely dilated left ventricle and severely diminished biventricular function (Fig. 1). She was treated with milrinone and epinephrine infusions, mechanical ventilation and listed for heart transplant. She underwent Berlin Heart EXCOR biventricular assist device (BiVAD) placement (30 ml LVAD and 25 ml RVAD pumps). No supraventricular tachycardia (SVT) was inducible or noted during her hospitalization...
November 2018: Journal of Electrocardiology
Christopher S Lee, James O Mudd, Karen S Lyons, Quin E Denfeld, Corrine Y Jurgens, Bradley E Aouizerat, Jill M Gelow, Christopher V Chien, Emily Aarons, Kathleen L Grady
BACKGROUND: We have a limited understanding of the biological underpinnings of symptoms in heart failure (HF), particularly in response to left ventricular assist device (LVAD) implantation. OBJECTIVES: The aim of this study was to quantify the degree to which symptoms and biomarkers change in parallel from before implantation through the first 6 months after LVAD implantation in advanced HF. METHODS: This was a prospective cohort study of 101 patients receiving an LVAD for the management of advanced HF...
November 27, 2018: Journal of Cardiovascular Nursing
Jae Hwan Choi, Matthew P Weber, Dylan P Horan, Jessica G Y Luc, Kevin Phan, Sinal Patel, Syed-Saif Abbas Rizvi, Elizabeth J Maynes, Gordon R Reeves, John W Entwistle, Rohinton J Morris, H Todd Massey, Vakhtang Tchantchaleishvili
Left ventricular assist device (LVAD) withdrawal with ventricular recovery represents the optimal outcome for patients previously implanted with an LVAD. The aim of this systematic review was to examine the patient outcomes of device withdrawal via minimally invasive pump decommissioning as compared with reoperation for pump explantation. An electronic search was performed to identify all studies in the English literature assessing LVAD withdrawal. All identified articles were systematically assessed for inclusion and exclusion criteria...
November 27, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Kiran K Mirza, Mette H Jung, Per E Sigvardsen, Klaus F Kofoed, Marie B Elming, Kasper Rossing, Finn Gustafsson
Using four-dimensional (4D) cardiac computed tomography (CCT) scans at rest and immediately after exercise, we examined the right heart chamber sizes and systolic function and its association with exercise capacity in left ventricular assist device (LVAD) recipients. Fifteen patients with HeartMate (HM) II or 3 underwent echocardiography and maximal cardiopulmonary exercise test. Subsequently, contrast-enhanced CCT scans were performed at rest and immediately after two minutes of supine 25 Watt ergometer bike exercise...
November 27, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Alanna A Morris, Christopher Chen, S Raja Laskar, Andrew L Smith, J David Vega
OBJECTIVE: It remains unclear whether left ventricular assist device (LVAD) implantation in non-inotrope dependent patients is of clinical benefit. This study sought to evaluate cause of death in patients listed for heart transplant (HT) to determine the relative risks and benefits of implanting LVAD into patients who are less sick than those included in the original clinical trials. METHODS: We examined death as the primary outcome in 23,098 patients listed for HT from 2006 to 2014 using proportional subdistribution hazards modeling...
November 9, 2018: International Journal of Cardiology
Ryuichiro Abe, Atsuhiro Matsumoto, Ryota Sakaguchi, Koichi Toda, Yoshiki Sawa, Akinori Uchiyama, Yuji Fujino
Objective: We assessed what predicts nutritional adequacy at day 14 following implantation of left ventricular assist device (LVAD). Method: We retrospectively reviewed the cases of 97 adult patients who underwent LVAD implantation at our institution from June 2011 to June 2016. We divided the patients into two groups based on the administered enteral nutrition (EN) calories on post-operative day (POD) 14: the EN calories of group SEN (sufficient enteral nutrition) were >80% of their total target calories, or the EN calories of group IEN (insufficient enteral nutrition) were <80% of their total target calories...
2018: Nutrition and Metabolic Insights
Christos Zormpas, Johanna Mueller-Leisse, Thorben Koenig, Jan D Schmitto, Christian Veltmann, David Duncker
BACKGROUND: Implantation of a left ventricular assist device (LVAD) leads to a diverse spectrum of changes on the twelve-lead surface electrocardiogram (ECG). We aimed to elucidate the changes of the surface ECG in patients after LVAD implantation potentially impacting ECG based screening tests of subcutaneous implantable cardioverter-defibrillators (S-ICD). METHODS: Patients from 2005 until 2017 with a documented twelve-lead ECG before and after LVAD implantation were included...
November 2, 2018: Journal of Electrocardiology
Vincent M Pronesti, Clara Antoury, Ricardo Mitre
Spigelian hernias are uncommon and predominantly affect the abdominal wall.The incidence of Spigelian hernias after colonoscopy is even rarer with only one case outlined in the surgical literature. This is the case of a 66-year-old man who underwent routine colonoscopy and presented to the hospital with systemic inflammatory response syndrome (SIRS). A computed tomography (CT) scan demonstrated a Spigelian hernia in the location of a prior left ventricular assist device (LVAD) placement. This required surgical resection and resulted in a complicated post-operative course...
September 17, 2018: Curēus
Judy Dillworth, Victoria Vaughan Dickson, Alex Reyentovich, Michele G Shedlin
OBJECTIVES: To understand how patients make decisions regarding a left ventricular assist device (LVAD). DESIGN: A qualitative multiple case study design was used to explore the context and influence of individuals regarding patients' decision-making processes through: 1) detailed, in-depth interviews of those mostly involved in the patient's decision and 2) pertinent data including observations, medical records, educational information and physical artifacts. Data clusters and patterns of co-occurring codes were examined using thematic analysis...
November 22, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Nir Uriel, Diego Medvedofsky, Teruhiko Imamura, Jiri Maly, Eric Kruse, Peter Ivák, Poornima Sood, Roberto M Lang, Francesco Maffessanti, Dominik Berliner, Johann Bauersachs, Axel Haverich, Michael Želízko, Ivan Netuka, Jan D Schmitto
BACKGROUND: The HeartMate3 (HM3) is a Conformiteé Européenne mark-approved left Ventricular (LV) assist device (LVAD) with fully-magnetically levitated rotor and features consisting of wide range operational speeds, wide flow paths and artificial pulse. We performed a hemodynamic-echocardiographic speed optimization evaluation in HM3 implanted patients to achieve optimal LV- and right-ventricular (RV) shape. METHODS: Sixteen HM3 patients underwent pump speed ramp-tests with right-heart catheterization...
November 22, 2018: Journal of Cardiac Failure
Devon E Cross, Tyler M Bauer, Vakhtang Tchantchaleishvili
To date, 3D organ modeling has not reached widespread clinical use, despite showing promise in medical literature. The majority of anatomic modeling that is presented in the literature is performed with proprietary software, presenting certain barriers to use such as price for usage rights. Open-source software not only circumvents this barrier, but also often provides greater customization offered by global communities. In this proof-of-concept experiment, a HeartMate II LVAD was "virtually fit" in a patient's left ventricle using only open-source software...
November 23, 2018: Artificial Organs
Vivek Rai, Julita Sacharczuk, Mirosława Dudyńska, Rafał Żurek, Magdalena Czerzynska, Aleksander Szypulski, Elżbieta Wójcik, Jerzy Pacholewicz, Janusz Skalski, Tomasz Mroczek
THE AIM: The aim of the study is to present the initial experience with continuous flow left ventricle assist device (CF-LVAD) in pediatric patients with BSA below 1.5 m2. MATERIAL AND METHODS: Between 2016 and 2017, CF-LVAD (the Heartware System) have been implanted in three pediatric patients in the Department of Pediatric Cardiac Surgery, Jagiellonian University, Krakow, Poland. The indications for initiating CF-LVAD were end-stage congestive heart failure due to dilated cardiomyopathy in all children...
2018: Folia Medica Cracoviensia
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"