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https://www.readbyqxmd.com/read/28642788/comparison-between-intestinal-beh%C3%A3-et-s-disease-and-crohn-s-disease-in-characteristics-of-symptom-endoscopy-and-radiology
#1
Tianyu Zhang, Liwen Hong, Zhengting Wang, Rong Fan, Maochen Zhang, Yun Lin, Mengmeng Cheng, Xiaolin Zhou, Peijun Sun, Xiaoyi Lin, Jie Zhong
AIM: To evaluate different parameters in differentiating intestinal BD from CD. METHODS: The medical records of inpatients with intestinal BD and CD were retrospectively reviewed. The univariate value of different parameters was analyzed, respectively. A differentiation model was established by pooling all valuable parameters together. Diagnostic efficacy was evaluated, and a receiver operating curve (ROC) was plotted. RESULTS: Forty-two BD patients and ninety-seven CD patients were reviewed...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28630777/magnetic-resonance-enterography-findings-of-intestinal-beh%C3%A3-et-disease-in-a-child
#2
Tommaso D'Angelo, Romina Gallizzi, Claudio Romano, Giuseppe Cicero, Silvio Mazziotti
Behçet's disease (BD) is a multisystem disorder of unknown aetiology, characterized by recurrent oral ulcers, genital ulcers, uveitis, skin lesions, and pathergy. Gastrointestinal disease outside the oral cavity is well recognized and usually takes the form of small intestinal ulcers, with the most significant lesions frequently occurring in the ileocaecal region. Symptoms usually include nausea, vomiting, colicky abdominal pain, and change in bowel habit and it is not unusual that patients may present late, with life-threatening complications requiring surgery...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28601086/burden-and-characteristics-of-hiv-infection-among-female-sex-workers-in-kampala-uganda-a-respondent-driven-sampling-survey
#3
Wolfgang Hladik, Andrew L Baughman, David Serwadda, Jordan W Tappero, Rachel Kwezi, Namakula D Nakato, Joseph Barker
BACKGROUND: Sex workers in Uganda are at significant risk for HIV infection. We characterized the HIV epidemic among Kampala female sex workers (FSW). METHODS: We used respondent-driven sampling to sample FSW aged 15+ years who reported having sold sex to men in the preceding 30 days; collected data through audio-computer assisted self-interviews, and tested blood, vaginal and rectal swabs for HIV, syphilis, neisseria gonorrhea, chlamydia trachomatis, and trichomonas vaginalis...
June 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28600969/prognostic-factors-and-treatment-outcomes-in-444-patients-with-mucosal-melanoma
#4
Markus V Heppt, Alexander Roesch, Benjamin Weide, Ralf Gutzmer, Friedegund Meier, Carmen Loquai, Katharina C Kähler, Anja Gesierich, Markus Meissner, Dagmar von Bubnoff, Daniela Göppner, Max Schlaak, Claudia Pföhler, Jochen Utikal, Lucie Heinzerling, Ioana Cosgarea, Jutta Engel, Renate Eckel, Alexander Martens, Laura Mirlach, Imke Satzger, Gabriele Schubert-Fritschle, Julia K Tietze, Carola Berking
BACKGROUND: Mucosal melanoma (MM) is a rare but diverse cancer entity. Prognostic factors are not well established for Caucasians with MM. PATIENTS AND METHODS: We analysed the disease course of 444 patients from 15 German skin cancer centres. Disease progression was determined with the cumulative incidence function. Survival times were estimated with the Kaplan-Meier method. Prognostic parameters were identified with multivariate Cox regression analysis. RESULTS: Common anatomic sites of primary tumours were head and neck (MMHN, 37...
June 7, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28600331/does-maternal-hsv-2-coinfection-increase-mother-to-child-transmission-of-hiv-a-systematic-review
#5
REVIEW
Vishalini Sivarajah, Kevin Venus, Mark H Yudin, Kellie E Murphy, Steven A Morrison, Darrell Hs Tan
BACKGROUND: Reducing HIV mother-to-child transmission (MTCT) is critical to ending the HIV pandemic. Reports suggest that herpes simplex virus-2 (HSV-2), a common coinfection in HIV-infected individuals, is associated with increased MTCT, but results have been conflicting. We conducted a systematic review of observational studies to quantify the magnitude of this relationship (PROSPERO no. CRD42016043315). METHODS: We searched Medline (1981 to June week 3, 2016), EMBASE (1981 to week 26, 2016), relevant conferences (2013-2016) and bibliographies of identified studies for cohort and case-control studies enrolling HIV-positive women during pregnancy or peripartum that quantified the effect of HSV-2 infection on MTCT...
June 9, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28570256/the-vulva-an-uncommon-presentation-of-a-pressure-ulcer
#6
Elena Conde Montero, José María Martínez Gómiz, Pablo de la Cueva Dobao
Pressure ulcers may develop in different locations. Vulvar pressure ulcers can be easily misdiagnosed and, moreover, have been rarely reported in the literature. Surgical procedures that involve prolonged pressure on this area may trigger these lesions. CASE REPORT: The authors present a case of a vulvar pressure ulcer secondary to the use of a perineal post to provide countertraction during surgical repair of a hip fracture. Diagnosis was made after excluding other possible causes with anatomopathological and microbiological analysis...
May 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28546103/neurological-manifestations-of-beh%C3%A3-et-s-disease-case-report-and-literature-review
#7
Alba López Bravo, Carlos Parra Soto, Elena Bellosta Diago, Álvaro Cecilio Irazola, Sonia Santos-Lasaosa
Neurological involvement in Behçet's disease is rare, especially at the onset. It can present in the form of parenchymal changes or as damage to the vascular structures in its nonparenchymal form. The coexistence of both kinds of manifestations in the same patient is exceptional. We report the case of a 32-year-old patient with a history of deep venous thrombosis, who was being treated for holocranial headache, apathy, and oral and genital ulcers. Brain magnetic resonance imaging showed hyperintense lesions in the basal ganglia and white matter, and the vascular study evidenced venous thrombosis of the left transverse sinus...
May 22, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28543798/mucosal-melanoma-clinical-histological-and-c-kit-gene-mutational-profile-of-86-french-cases
#8
E Cinotti, J Chevallier, B Labeille, F Cambazard, L Thomas, B Balme, M T Leccia, M D'Incan, P Vercherin, C Douchet, P Rubegni, J L Perrot
BACKGROUND: Mucosal melanomas are rare and highly aggressive tumors. Few studies evaluated mucosal melanomas of locations other than the head and neck region, and other than those of the Asian population. OBJECTIVES: The objective of this study was to analyze the clinical and histological features, as well as the mutational status of c-kit and b-raf gene of mucosal melanoma in any localization in a French series. METHODS: We investigated clinical (sex, age, performance status, survival, treatment of the patients and lack of pigmentation of the tumors) and histopathologic features (ulceration, Breslow's index, mitotic rate), as well as the mutational status of c-kit and b-raf of 86 mucosal melanomas diagnosed in 15 years in four French University Hospitals...
May 22, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28538857/-hand-foot-and-mouth-disease-in-a-hospital-in-callao-in-2016
#9
Milton José Max Rodríguez-Zúñiga, Katherine Vértiz-Gárate, Florencio Cortéz-Franco, Eberth Qujiano-Gomero
Hand, foot, and mouth disease (HFMD) is an exanthematous viral disease caused mainly by Coxsackie A16 with a typical symptomatology of fever, papulovesicular rash on the hands, feet, and genitals, and an ulcerous enanthem in the mouth. In the summer of 2016, a variety of cases presented at a hospital in Callao in children and adults with a symptomatology consistent with HFMD. A clinical diagnosis was made, and support therapy was applied, resulting in the resolution of symptoms. In the last decade, reports have emerged in some countries of an atypical involvement caused by Coxsackie A6, producing lesions that are more widely distributed in adults...
January 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28526427/atypical-presentations-of-cutaneous-leishmaniasis-a-systematic-review
#10
REVIEW
Camilla Barros Meireles, Laís Chaves Maia, Gustavo Coelho Soares, Ilara Parente Pinheiro Teodoro, Maria do Socorro Vieira Gadelha, Cláudio Gleidiston Lima da Silva, Marcos Antonio Pereira de Lima
Cutaneous Leishmaniasis (CL) is endemic in 88 countries, showing relevant prevalences. The aim of this study was to perform a systematic review on atypical lesions of CL around the world, addressing clinico-epidemiological, immunological and therapeutic aspects. A search of the literature was conducted via electronic databases Scopus and PubMed for articles published between 2010 and 2015. The search terms browsed were "cutaneous leishmaniasis", "atypical" and "unusual". Based on the eligibility criteria, 34 out of 122 articles were included in the final sample...
August 2017: Acta Tropica
https://www.readbyqxmd.com/read/28521725/hiv-and-syphilis-prevalence-and-associated-risks-in-the-cameroonian-armed-forces
#11
Michael Grillo, Bonnie Robin Tran, Ubald Tamoufe, Cyrille F Djoko, Karen Saylors, Kelly Woodland, Ltc Wangmene, Caroline Macera
BACKGROUND: Continued surveillance of the HIV epidemic is critical to monitor changes in trends and risk behaviors. A 2005 study in the Cameroonian Armed Forces (CAF) found an HIV prevalence of 11.3% among male and female service members. The purpose of the current study is to determine the 5-year change in the HIV prevalence, estimate the prevalence of syphilis, and examine factors associated with infection in the CAF. METHODS: Participants were male and female service members 18 years of age or older who were stationed at one of the 10 military garrisons selected for participation...
May 16, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28515628/epidemiology-of-herpes-simplex-virus-type-1-and-2-in-italy-a-seroprevalence-study-from-2000-to-2014
#12
REVIEW
S Marchi, C M Trombetta, R Gasparini, N Temperton, E Montomoli
Herpes simplex viruses (HSV) are among the most widespread causative agents of human viral infections. HSV-2 is one of the commonest causes of genital disease, while HSV-1 is associated primarily with orolabial ulceration; however, recent changes in HSV epidemiology showed an increase in genital and neonatal herpes particularly caused by HSV-1. The main purpose of this study was to assess the seroprevalence of HSV-1 and HSV-2 in a random population in Siena (central Italy) in 2000, 2005 and 2013-2014 and in Bari (southern Italy) in 2005...
March 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28481687/a-trivalent-subunit-antigen-glycoprotein-vaccine-as-immunotherapy-for-genital-herpes-in-the-guinea-pig-genital-infection-model
#13
Sita Awasthi, Lauren M Hook, Carolyn E Shaw, Harvey M Friedman
An estimated 417 million people worldwide ages 15 to 49 are infected with herpes simplex virus type 2 (HSV-2), the most common cause of genital ulcer disease. Some individuals experience frequent recurrences of genital lesions, while others only have subclinical infection, yet all risk transmitting infection to their intimate partners. A vaccine was developed that prevents shingles, which is a recurrent infection caused by varicella-zoster virus (VZV), a closely related member of the Herpesviridae family. The success of the VZV vaccine has stimulated renewed interest in a therapeutic vaccine for genital herpes...
May 8, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28469158/evaluating-the-utility-of-syndromic-case-management-for-three-sexually-transmitted-infections-in-women-visiting-hospitals-in-delhi-india
#14
Subash Chandra Sonkar, Kirti Wasnik, Anita Kumar, Vineeta Sharma, Pratima Mittal, Prashant Kumar Mishra, Mausumi Bharadwaj, Daman Saluja
Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiveness and/or inadequacies of SCM, 11000 women were recruited and examined by clinicians for infection by Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), Bacterial vaginosis (BV) and others...
May 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28448097/sudden-genital-ulceration-in-a-young-man-a-quiz
#15
Marco Cusini, Susanna Benardon, Michaela Brena, Stefano Ramoni, Vinicio Boneschi, Raffaele Gianotti
No abstract text is available yet for this article.
April 27, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28442813/acral-pebbles-a-novel-manifestation-of-partially-treated-syphilis
#16
Vijay Zawar, Tarang Goyal
Atypical manifestations in syphilis are known and pose a diagnostic dilemma. Early suspicion, timely investigations, diagnosis, and treatment, is the key to successful management. We report a patient of secondary syphilis, who presented as genital ulcer and small pebbles like eruptions on the palmar aspect of his fingers.
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28412856/investigating-the-role-of-il-33-in-the-pathogenesis-of-beh%C3%A3-et-s-disease
#17
Pamir Çerçi, Seda Altıner, Ali İnal, Kenan Köse, Göksal Keskin, Ümit Ölmez
OBJECTIVES: Behçet's disease (BD) is an inflammatory disease, characterized by oral aphthous lesions, recurrent uveitis, skin lesions, and genital ulcerations. Increased release of several cytokines may play a role in the inflammatory stages of BD. IL-33, a member of the IL-1 cytokine superfamily, plays an important role in inflammation. We analyzed serum IL-33 concentration in BD patients to assess its possible role in the pathophysiology of this disease. METHODS: The study included 54 BD patients, 31 with active BD and 23 with inactive BD as well as 18 matched healthy controls...
April 17, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28407649/lymphogranuloma-venereum-serovar-l2b-presenting-with-painful-genital-ulceration-an-emerging-clinical-presentation
#18
Roger Haber, Ismaël Maatouk, Bertille de Barbeyrac, Martine Bagot, Michel Janier, Sébastien Fouéré
These 5 cases of atypical inflammatory lymphogranula venereum (LGV) serovar L2b presenting initially with edema and persistent painful ulceration illustrate that clinical manifestations of LGV in the current outbreak in men who have sex with men reflect the influence of both the serovars virulence and the host immune system and are not confined to proctitis. L2b serovar could have a particular high virulence profile, and the need for awareness of LGV as a cause of genital ulceration is crucial.
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28406423/epidemiological-aspects-of-genital-ulcers-at-the-sti-center-of-the-national-institute-of-public-hygiene-abidjan-c%C3%A3-te-d-ivoire-2008-to-2010
#19
D Z Gakoué, I Tiembré
Genital ulcers are among the seven syndromes of sexually transmitted infections (STIs) identified in Côte d'Ivoire. Ulcerative STIs present a public health problem because of their frequency and their role in the spread of HIV. Our objective was to investigate the epidemiological characteristics of genital ulcers observed in the STI center of the National Institute of Public Hygiene in Abidjan. This cross-sectional, descriptive and analytical study examined cases seen at the center in 2008 through 2010. We retrospectively reviewed all files of clients aged 10 and older who sought care for the first time at the STI center and received a clinical diagnosis, confirmed by the laboratory, of a STI...
February 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28406402/beh%C3%A3-et-disease-in-western-algeria
#20
M E A Ghembaza, N Bouabdallah, A Lounici
The aim of the current study was to describe the epidemiological and clinical features of Behçet disease in western Algeria. This observational retrospective study examined records for patients with Behçet disease seen in our department from 1990 to 2015. Of the 61 patients included in the study, 80.3% were men, for a sex ratio of 4.08. The mean age at onset was 27.2±7 years, and the mean interval between the onset of symptoms and diagnosis was 4.8±6.3 years. Dermatologic manifestations were the most common finding...
February 1, 2017: Médecine et Santé Tropicales
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