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Liver And Surgery

Masami Takagaki, Hiroki Yamaguchi, Naoko Ikeda, Kaori Takeda, Fumihito Kasai, Kiyotaka Yahagi, Shunji Kanzaki, Shinichi Mitsuyama, Tasuku Kadowaki, Toru Kotani
We present the cases of eight patients (mean age 75 years; EuroSCORE II 17.0 ± 22.0) who underwent post-cardiotomy venovenous extracorporeal membrane oxygenation (ECMO) without heparinization due to serious bleeding. Three liver cirrhosis, two chronic hemodialysis, three redo sternotomy, and two urgent surgery cases were included. Respiratory ECMO Survival Prediction score was - 5.1 ± 4.2 (estimated survival rate: approximately 30%). Mean ECMO duration was 14 days with 9 circuit exchanges. Five patients were weaned from ECMO and three were discharged alive at 90 days (survival 37...
August 17, 2018: General Thoracic and Cardiovascular Surgery
Eisuke Nakazawa, Shoichi Maeda, Keiichiro Yamamoto, Aru Akabayashi, Yuzaburo Uetake, Margie H Shaw, Richard A Demme, Akira Akabayashi
BACKGROUND: This paper examines the ethical aspects of organ transplant surgery in which a donor heart is transplanted from a first recipient, following determination of death by neurologic criteria, to a second recipient. Retransplantation in this sense differs from that in which one recipient undergoes repeat heart transplantation of a newly donated organ, and is thus referred to here as "reuse cardiac organ transplantation." METHODS: Medical, legal, and ethical analysis, with a main focus on ethical analysis...
August 17, 2018: BMC Medical Ethics
Xuesong Xu, Menghao Wang, Jin-Zheng Li, Si-Dong Wei, Hao Wu, Xing Lai, Ding Cao, Zhi-Bing Ou, Jianping Gong
The aim of this study is to investigate the protective effect and the mechanism of tauroursodeoxycholic acid (TUDCA) against hepatic ischemia reperfusion (IR) injury. Male Balb/c mice were intraperitoneally injected with tauroursodeoxycholic acid (400 mg/kg) or saline solution, once per day for 3 days before surgery, and then the model of hepatic I/R injury was established. Blood and liver samples were collected from each group at 3, 6, and 24 h after surgery. Liver pathological changes, liver function, hepatocyte apoptosis and proinflammatory factors were detected...
July 20, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Tuba Apaydın, Mustafa Deniz
INTRODUCTION: Cystic echinococcosis is an endemic disease in east Turkey. Echinococcosis granulosus is reported as the most common agent of cystic echinoccocus. Hydatid cysts are generally involved in lung and liver. PRESENTATION OF CASE: 37 year old female admitted to our clinic with cough and expectoration of watery material progressing within 3 months. Thorax CT demonstrated a 110*100 mm well defined cavitary lesion in the right lower lobe of the lung. The patient was treated with cystotomy & capitonnage and postoperative albendazole treatment successfully...
August 9, 2018: International Journal of Surgery Case Reports
Francesco Guerra, Michele Di Marino, Andrea Coratti
BACKGROUND: The laparoscopic methods for major abdominal surgery are gaining increasing acceptance worldwide. Despite its relatively recent introduction in clinical practice, robotics has been accepted as an effective option to perform high-demanding procedures such as those required in hepatobiliary surgery. Some potential advantages over conventional laparoscopy have been suggested, but its actual role in clinical practice is still to be defined. METHODS: The objective of this work is to critically review the available evidence on the application of robotic surgery to the liver and biliary tract...
August 17, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Yiren Hu, Sunwu You, Zhangwei Yang, Shuqun Cheng
BACKGROUND: The aim of this study was to combine clinicopathologic variables associated with overall survival and disease-free survival after curative resection for hepatocellular carcinoma (HCC) with portal vein tumour thrombus (PVTT) into a prediction nomogram. METHODS: We retrospectively analysed 358 patients who underwent curative resection for HCC with PVTT at the Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai, China...
August 17, 2018: ANZ Journal of Surgery
Marc Beaussier, Alain Delbos, Axel Maurice-Szamburski, Claude Ecoffey, Luc Mercadal
Lidocaine is an amide local anaesthetic initially used intravenously as an antiarrhythmic agent. At some point it was proposed that intravenous lidocaine (IVL) had an analgesic effect that could be potentially beneficial in perioperative settings. Since these preliminary reports, a large body of evidence confirmed that IVL had anti-inflammatory and opiate-sparing effects, a combination of characteristics leading to an array of effects such as a decrease in postoperative pain and opiate consumption, and a reduction in the duration of digestive ileus...
August 16, 2018: Drugs
Yesheng Li, Yi Chen, Xinji Zhang, Li Geng, Binghua Dai, Xin Lv, Ping Zhang, Honghai Li, Jiamei Yang, Yangqing Huang, Feng Xu
Liver ischemia-reperfusion injury is an important clinical complication in which excessive inflammation is a key factor; however, few studies have provided effective means of its regulation. As previous studies suggested that electro-acupuncture (EA) is able control excessive inflammation, the present study aimed to explore its effects on liver ischemia-reperfusion injury in experimental rats. The animals were randomly divided into surgery and sham groups, which were further divided into four sub-groups, including a non-treatment (NT), a non-point acupuncture (NPA), the non-selective nicotinic acetylcholine receptor (AChR) agonist 1,1-dimethyl-4-phenyl L-pioperazinium iodide (DMPPI) and an EA group...
August 2018: Experimental and Therapeutic Medicine
Ilenia Bartolini, Maria Novella Ringressi, Filippo Melli, Matteo Risaliti, Marco Brugia, Enrico Mini, Giacomo Batignani, Paolo Bechi, Luca Boni, Antonio Taddei
Background: Surgical treatment is the cornerstone in the management of colorectal cancer (CRC) liver metastases. The aim of this study is to identify clinicopathological factors affecting disease-free (DFS) and overall survival (OS) in patients undergoing potentially curative liver resection for CRC metastasis. Methods: All consecutive patients undergoing liver resection for first recurrence of CRC from February 2006 to February 2018 were included. Prognostic impact of factors related to the patient, primary and metastatic tumors, was retrospectively tested through univariate and multivariate analyses...
2018: Gastroenterology Research and Practice
Da Zhou, Jiayue Ding, Jingyuan Ya, Liqun Pan, Yuan Wang, Xunming Ji, Ran Meng
Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI) encountered, particularly amongst elderly patients with clinical scenarios, such as age-related arteriosclerotic vascular disease, heart surgery and organ transplantation, is still an unsettled conundrum that besets clinicians. Remote ischemic conditioning (RIC), delivered via transient, repetitive noninvasive IR interventions to distant organs or tissues, is regarded as an innovative approach against IRI. Based on the available evidence, RIC holds the potential of affording protection to multiple organs or tissues, which include not only the heart and brain, but also others that are likely susceptible to IRI, such as the kidney, lung, liver and skin...
August 16, 2018: Aging
Francesca Ratti, Federica Cipriani, Guido Fiorentini, Camila Hidalgo Salinas, Marco Catena, Michele Paganelli, Luca Aldrighetti
BACKGROUND: The primary endpoint of this study was to evaluate the outcome of surgery for perihilar cholangiocarcinoma in a high-volume tertiary referral center. METHODS: The study population consisted of 196 consecutive patients with histologically confirmed perihilar cholangiocarcinoma-PHC-who were candidates to surgical treatment. Factors affecting postoperative morbidity were evaluated in the whole series (primary endpoint) and after stratification of patients according to the following criteria: (a) perioperative management protocol implementation; (b) monocentric management (secondary endpoint)...
July 17, 2018: Digestive and Liver Disease
R A Ibadov, A Kh Babadzhanov, S Kh Irmatov, N R Gizatulina, S Kn Ibragimov, S A Ruziboev
AIM: Here we analyze efficiency of the algorithm for intensive therapy of acute hepatic insufficiency in patients with cirrhosis after portosystemic shunting, based on the experience of the Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V.V. Vakhidov and considering recommendations of the world's leading hepatology schools. MATERIAL AND METHODS: Algorithm efficiency was analyzed based on the results of portosystemic shunting of 556 patients with cirrhosis and acute liver insufficiency...
2018: Khirurgiia
Yu A Kovalenko, V A Vishnevsky, A V Chzhao, Yu O Zharikov
AIM: To develop new criteria of radical surgery for hilar cholangiocarcinoma (HCC). MATERIAL AND METHODS: There were 165 HCC patients who underwent surgery in 1986-2016 at the Vishnevsky Institute of Surgery. TNM stage distribution: stage I - 4 (2.4%), II - 45 (27.3%) (29 of them are referred to the 1st period of work), IIIA - 23 (13.9%), IIIB - 41 (24.8%), IVA - 35 (21.2%), IVB - 17 (10.3%). 80 (48%) patients underwent hemihepatectomy, 17 (10%) - advanced hemihepatectomy, 16 (10%) - minor liver resection with common bile duct repair, 52 (32%) - common bile duct repair resection...
2018: Khirurgiia
Xiu-Ping Zhang, Xu-Biao Wei, Zhen-Hua Chen, Shu-Qun Cheng
No abstract text is available yet for this article.
August 14, 2018: Annals of Surgery
Masahiko Kubo, Hiroshi Wada, Hidetoshi Eguchi, Kunihito Gotoh, Yoshifumi Iwagami, Daisaku Yamada, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Shogo Kobayashi, Masahisa Nakamura, Yusuke Ono, Keigo Osuga, Eigoro Yamanouchi, Yuichiro Doki, Masaki Mori
BACKGROUND: Magnetic compression anastomosis (MCA) is a minimally invasive method of anastomosis that does not involve a surgical procedure in patients with stricture, obstruction, or dehiscence of anastomosis after surgery. We experienced a case of complete dehiscence of bilioenteric anastomosis that was successfully treated by MCA. CASE PRESENTATION: A 55-year-old woman received ABO-incompatible right-lobe living-donor liver transplantation with hepaticojejunostomy for the right anterior duct (RAD) and right posterior duct (RPD)...
August 15, 2018: Surgical Case Reports
Wei Qin, Pengcheng Kang, Yi Xu, Kaiming Leng, Zhenglong Li, Lining Huang, Jianjun Gao, Yunfu Cui, Xiangyu Zhong
Cholangiocarcinoma (CCA) arising from the neoplastic transformation of cholangiocytes with increasing incidence in the worldwide. Unfortunately, a large amount of CCA patients lost their chance for surgery because it is hard to diagnose in the early stages. Long non-coding RNAs (lncRNAs) is closely associated with development and progression of various malignant tumors. Hox transcript antisense intergenic (HOTAIR), a negative prognostic factor for patients with gastric, liver and pancreatic carcinoma. Its transcription levels and functional roles in CCA is still unknown...
August 15, 2018: Scientific Reports
Robbert S Puijk, Alette H Ruarus, Laurien G P H Vroomen, Aukje A J M van Tilborg, Hester J Scheffer, Karin Nielsen, Marcus C de Jong, Jan J J de Vries, Babs M Zonderhuis, Hasan H Eker, Geert Kazemier, Henk Verheul, Bram B van der Meijs, Laura van Dam, Natasha Sorgedrager, Veerle M H Coupé, Petrousjka M P van den Tol, Martijn R Meijerink
BACKGROUND: Radiofrequency ablation (RFA) and microwave ablation (MWA) are widely accepted techniques to eliminate small unresectable colorectal liver metastases (CRLM). Although previous studies labelled thermal ablation inferior to surgical resection, the apparent selection bias when comparing patients with unresectable disease to surgical candidates, the superior safety profile, and the competitive overall survival results for the more recent reports mandate the setup of a randomized controlled trial...
August 15, 2018: BMC Cancer
A Gils Contreras, A Bonada Sanjaume, M Montero Jaime, A Rabassa Soler, F Sabench Pereferrer, A Molina López, N Becerra Tomás, D Del Castillo Déjardin, J Salas-Salvadó
OBJECTIVE: To assess which type of preoperative dietary strategy is most effective in reducing liver volume and assessing its influence on different biochemical parameters and on surgical complications in individuals undergoing bariatric surgery. METHODS: Parallel randomized trial comparing the effect of a very low calorie diet (VLCD) and a low calorie diet (LCD) for a period of 21 days before surgery on hepatic volume, anthropometric and biochemical parameters...
August 14, 2018: Obesity Surgery
Qinyu Chen, Fabio Bagante, Griffin Olsen, Katiuscha Merath, Jay J Idrees, Eliza W Beal, Ozgur Akgul, Jordan Cloyd, Mary Dillhoff, Carl Schmidt, Susan White, Timothy M Pawlik
BACKGROUND: The impact of time to readmission (TTR) on post-discharge mortality has not been well examined. We sought to define the impact of TTR on postoperative mortality after liver or pancreas surgery. METHODS: A retrospective cohort analysis of liver and pancreas surgical patients was conducted using 2013-2015 Medicare Provider Analysis and Review database. Patients were subdivided into TTR groups: 1-5 days, 6-15, 15-30, 31-60, 61-90, and no readmission. The association of index complication, readmission causes, TTR, and mortality was assessed...
August 14, 2018: World Journal of Surgery
M Schmelzle, F Krenzien, W Schöning, J Pratschke
BACKGROUND AND OBJECTIVES: The treatment of hepatocellular carcinoma (HCC) includes surgical, interventional and systemic approaches. This review highlights the importance of surgical treatment approaches in the multimodal treatment of HCC, based on the currently available literature, corresponding German guidelines as well as current developments in organ donation in Germany. RESULTS: Curative treatment options for HCC include liver transplantation, partial liver resection, and local ablative procedures depending on the lesion size...
August 14, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
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