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Yelin Lou, Yimin Zhou, Hong Lu, Weiguo Lyu
OBJECTIVE: To establish a prognostic model for preterm birth in women after cervical conization, and to evaluate its effectiveness. METHODS: Seventy three women after cervical conization in Women's Hospital of Zhejiang University were included for this retrospective study. The influencing factors of preterm delivery were analyzed by Logistic regression analysis and a prognostic model was created. Receiver operating characteristic (ROC) curve was used for evaluation of the predictive ability of the model...
February 25, 2018: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
María Reynel, Yván Villegas, Helmut Kiene, Paul G Werthmann, Gunver S Kienle
RATIONALE: Carcinoma in situ (CIS) of the uterine cervix is a premalignant condition of squamous epithelium. The standard treatments are excision and ablation procedures; for women with positive margins, hysterectomy is recommended. PATIENT CONCERNS: A 47-year-old Peruvian woman with recurrent candidal vaginitis had been diagnosed with colpocervicitis and squamous metaplasia 8 years ago, which were not treated. DIAGNOSES: The patient was diagnosed with CIS after cervical conization procedure...
November 2018: Medicine (Baltimore)
Chao Zhang, Hongyan Zhang, Linqing Yang, Yunfei Wang, Xiaoyu Li, Jinfeng Guo, Jing Xu
RATIONALE: Primary squamous cell carcinoma of the endometrium (PSCCE) is a rare entity, and only sporadic cases have been reported in the literature since the 1st report in 1892. This report describes a case of a perimenopausal woman with PSCCE. PATIENT CONCERNS: A 47-year-old, human papilloma virus type 16-positive, perimenopausal woman was admitted to our hospital with irregular vaginal bleeding for 6 months and secondary anemia. DIAGNOSES: The patient was diagnosed with stage IIIc primary and moderately differentiated endometrial squamous cell carcinoma...
November 2018: Medicine (Baltimore)
Giorgio Bogani, Elena Tagliabue, Stefano Ferla, Fabio Martinelli, Antonino Ditto, Valentina Chiappa, Umberto Leone Roberti Maggiore, Francesca Taverna, Claudia Lombardo, Domenica Lorusso, Francesco Raspagliesi
The widespread introduction of screening methods allow to identify cervical dysplasia before having invasive cancer. The risk of developing cervical dysplasia persistence/recurrence following conization represent a major health issue. Although several studies tried to identify predictors for cervical dysplasia persistence/recurrence, no previous study has been conducted to develop a risk calculator. The current study aimed to identify predictors of cervical dysplasia persistence/recurrence among women undergoing primary conization...
November 26, 2018: European Journal of Cancer Prevention
Masayuki Shintaku, Hiromi Taniguchi, Yoshihiro Yamamoto, Fumihiko Kono, Masahiro Sumitomo
Serous tubal intraepithelial carcinoma (STIC) has attracted attention as a precursor lesion of high-grade serous carcinoma (HGSC) of the ovary. We report the rare case of a woman in whom adenocarcinoma cells were detected in cervical smears and demonstrated to be derived from STIC in the fimbria. The patient was a 48-year-old woman, in whom cervical smears contained adenocarcinoma cells, but cervical conization did not reveal adenocarcinoma. Because the post-conization smears again demonstrated adenocarcinoma cells, hysterectomy with bilateral salpingectomy was performed 16 months after the first detection of adenocarcinoma cells in cervical smears...
October 30, 2018: Diagnostic Cytopathology
Sarah Schott, Judith Heinzler, Nathalie Rippinger, Thomas Bruckner, Janina Brucker, Janine Hoffmann, Nadja Dornhöfer, Christine Dinkic, Stephan Seitz, Joachim Rom, Christof Sohn, Timm C Schott
BACKGROUND: Dental and cervical controls are two established screening programs in Germany. Compliance to orthodontic treatment in childhood is essential for dental health and one of the first health interventions that requires adherent behavior; therefore, it may be associated with participation in further screening programs in adulthood. However, it is not yet known whether early orthodontic treatment influences long-term screening adherence. METHODS: Using a questionnaire administered during a visit to a special dysplasia outpatient service, this case-control study evaluated women's personal history of orthodontic care, long-term satisfaction, and dental and gynecological screening adherence...
October 30, 2018: Archives of Gynecology and Obstetrics
Limei Chen, Li Liu, Xiang Tao, Luopei Guo, Hongwei Zhang, Long Sui
OBJECTIVE: The aim of the study was to analyze the clinical outcomes of high-grade squamous intraepithelial lesion (HSIL) 6 months after loop electrosurgical excision procedure (LEEP). We explored the risk factors of persistent cervical HSIL after LEEP and evaluated the methods of follow-up. PATIENTS AND METHODS: This retrospective study included women who underwent a LEEP and had a diagnosis of HSIL in their LEEP specimen during 2011 to 2015. The purpose was to determine the risk factors among these women for having persistent HSIL disease at their 6-month follow-up visit...
October 26, 2018: Journal of Lower Genital Tract Disease
Liang Wang
Serial cervical length (CL) measurement in mid-trimester is recommended in post-conization pregnancy to estimate the risk of spontaneous preterm birth (SPTB). A short mid-trimester cervix (CL < 25 mm) has been considered as a strong predictor for SPTB. However, the low incidence of short cervix limits the utility of mid-trimester CL measurement in prediction of SPTB. A great proportion of women who develop SPTB don't have a short mid-trimester cervix. Therefore, this study was aimed to investigate the additional value of serial CL measurement in predicting SPTB in addition to detecting short cervix alone...
October 17, 2018: Scientific Reports
Jun-Yu Chen, Zhi-Ling Wang, Zhao-Yang Wang, Xing-Sheng Yang
The aim of this study was to illuminate risks factors of residual lesions, and recurrence of the high-grade cervical intraepithelial lesions (HSIL) patients with positive margin who underwent cervical conization.A retrospective cohort study of 218 patients with positive margin after conization, including cold knife conization (CKC) and loop electrosurgical excisional procedure (LEEP), and follow-up from 2013 through 2016. The diagnosis of residual disease and recurrence were established and confirmed by biopsy...
October 2018: Medicine (Baltimore)
Keiko Kigure, Kazuto Nakamura, Yoshikazu Kitahara, Kohshiro Nakao, Takashi Hirakawa, Shunichi Rokukawa, Masahiro Ito, Toshio Nishimura, Ikuro Ito, Issei Kagami, Shunichi Itoga
The incidence of cervical intraepithelial neoplasia(CIN) among reproductive-aged women has increased in Japan. Cervical conization is commonly applied for local cervical treatment to preserve fertility. The Shimodaira-Taniguchi (S-T) conization procedure is widely used in Japan. S-T conization uses a high-frequency current and a triangular probe with a linear excision electrode to remove cervical tissue as a single informative specimen. However, alternative of an electrosurgical scalpel (ES) has the advantage of adjusting the surgical margin to the transformation zone in order to preserve the maximum amount of healthy cervical tissue with good hemostasis...
October 2018: Medicine (Baltimore)
Rosa Oncins Torres, Mª Ángeles Aragón Sanz, Eduardo Clemente Roldán, Mª Dolores Comes García, Gorka Muñiz Unamunzaga, Lorena Guardia Dodorico, Víctor Vallés Gallego
OBJECTIVE: Uterine Cervical Cancer (UCC) screening has changed with the introduction of the High Risk Human Papilloma Virus test (HRHPV) and its evaluation is necessary. The objective of this study is to analyze the effectiveness of UCC screening with activities aimed at early detection and treatment to modify the natural history of the process and improve its prognosis. METHODS: Cytology and HR-HPV (co-testing) were performed according to the SEGO protocol of 2010 between 2011 and 2015 with follow-up until 2017...
October 2, 2018: Revista Española de Salud Pública
Munetoshi Akazawa, Toshiaki Saito, Masao Okadome, Kazuya Ariyoshi
OBJECTIVE: The aim of this study was to compare the outcomes associated with the use of a novel monopolar scalpel with those associated with the use of an ultrasonic scalpel for cervical conization of cervical intraepithelial neoplasia. MATERIALS AND METHODS: We conducted a retrospective cross-sectional study in patients treated in our institute between April 2010 and March 2017. We used either the VIO monopolar scalpel (VIO) or Harmonic ultrasonic scalpel (HS) for cervical conization...
September 26, 2018: Journal of Lower Genital Tract Disease
Katsufumi Otsuki, Satoshi Ando, Takeshi Nishi, Masatoshi Jimbo
Transvaginal cervicoisthmic cerclage was carried out in 12 such patients who were at high-risk of premature delivery. Patients who underwent transvaginal cervicoisthmic cerclage had undergone conization, cervical radical hysterectomy or another form of extensive cervical resection, or had a history of third-trimester miscarriage or premature delivery despite having previously undergone cervical cerclage several times for cervical incompetence. There were seven cases of pregnancy after extensive conization, and four had a history of failed cervical cerclage...
September 6, 2018: Journal of Obstetrics and Gynaecology Research
Maarit K Leinonen, Svenn A Hansen, Gry Baadstrand Skare, Inger Berit Skaaret, Monica Silva, Tom Børge Johannesen, Mari Nygård
BACKGROUND: Accurate information about treatment is needed to evaluate cervical cancer prevention efforts. We studied completeness and validity of reporting cervical treatments in the Cancer Registry of Norway (CRN). MATERIAL AND METHODS: We identified 47,423 (92%) high-grade cervical dysplasia patients with and 3983 (8%) without recorded treatment in the CRN in 1998-2013. We linked the latter group to the nationwide registry of hospital discharges in 1998-2015...
August 31, 2018: Acta Oncologica
Shinichi Togami, Toshihiko Kawamura, Mika Fukuda, Shintaro Yanazume, Masaki Kamio, Hiroaki Kobayashi
OBJECTIVE: To assess the clinicopathological characteristics and clinical management of patients diagnosed with mullerian adenosarcoma of the uterine cervix. MATERIALS AND METHODS: Records of six patients surgically treated for cervical mullerian adenosarcoma were reviewed. RESULTS: The median age of the patients was 50 years (range, 17-74). Four patients presented with vaginal bleeding and two of them had watery discharge as the primary symptoms...
August 2018: Taiwanese Journal of Obstetrics & Gynecology
Judith Heinzler, Janina Brucker, Thomas Bruckner, Christine Dinkic, Janine Hoffmann, Nadja Dornhöfer, Stephan Seitz, Christof Sohn, Joachim Rom, Timm C Schott, Sarah Schott
PURPOSE: In this case-control study, the impact on quality of life and sexual function in women with cervical dysplasia and conization will be evaluated, in order to address coping with such a premalignant lesion and to improve strategies for salutogenesis. METHODS: This multicenter case-control study evaluates women at special dysplasia outpatient clinic (T1) as well as 3 (T2) and 6 (T3) months after the diagnosis of a dysplasia. The women were subgrouped upon dysplasia only (S2) or dysplasia with conization (S1)...
October 2018: Archives of Gynecology and Obstetrics
Jill H Tseng, Alessia Aloisi, Yukio Sonoda, Ginger J Gardner, Oliver Zivanovic, Nadeem R Abu-Rustum, Mario M Leitao
OBJECTIVE: This study aimed to evaluate oncologic outcomes of women with stage IB1 cervical cancer treated with uterine-preserving surgery (UPS) (defined as conization or trachelectomy) versus non-UPS (defined as hysterectomy of any type). METHODS: The Surveillance, Epidemiology, and End Results (SEER) database was used to identify women younger than 45 years diagnosed with stage IB1 cervical cancer from 1998 to 2012. Only those who underwent lymph node (LN) assessment were included...
September 2018: International Journal of Gynecological Cancer
Joël Fokom Domgue, Kathleen M Schmeler
Recent advances in screening and early diagnosis have decreased cervical cancer incidence and mortality rates in high-resource settings. The postponement of childbearing, combined with an increased number of cervical cancer survivors, has yielded new paradigms in patient care. In recent years, radical surgery has been challenged as the standard of care for early-stage cervical cancer owing to its significant morbidity and fertility impairment. Attention has been directed to assessing more conservative procedures that can reduce treatment-induced morbidity without compromising oncologic safety and reproductive potential of patients with early-stage disease...
June 28, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
Yuyeon Jung, Ah Ra Lee, Sung-Jong Lee, Yong Seok Lee, Dong Choon Park, Eun Kyung Park
Objective: This study aimed to determine the factors affecting pathologic discrepancy and final diagnosis between colposcopic biopsy and pathology by loop electrosurgical excision procedure (LEEP). Methods: Between 2004 and 2016, 1,200 patients who underwent LEEP were enrolled for this study. 667 underwent cervical cytology, human papillomavirus (HPV) test, colposcopic biopsy, and LEEP. We analyzed patient's age, menopausal status, number of delivery, abortion times, cervical cytology, number of punch biopsies, HPV type, LEEP, and interval between colposcopic biopsy and LEEP...
July 2018: Obstetrics & Gynecology Science
Geum Joon Cho, Yung-Taek Ouh, Log Young Kim, Tae-Seon Lee, Geun U Park, Ki Hoon Ahn, Soon-Cheol Hong, Min-Jeong Oh, Hai-Joong Kim
BACKGROUND: The aim of this study was to determine the effect of cerclage in women who underwent cervical conization. METHODS: Study data were collected from the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service for 2009-2013. Women who had a conization in 2009 and a subsequent first delivery between 2009 and 2013 in Korea were enrolled. RESULTS: Among the women who had conization in 2009, 1075 women had their first delivery between 2009 and 2013...
July 3, 2018: BMC Pregnancy and Childbirth
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