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Benjamin W Sykes, Mark Bowen, Jocelyn L Habershon-Butcher, Martin Green, Gayle D Hallowell
BACKGROUND: To date, risk factors for equine glandular gastric disease (EGGD) have not been described in Thoroughbred racehorses. OBJECTIVES: To determine management factors associated with EGGD, identify clinical signs in affected horses, and compare these to equine squamous gastric disease (ESGD). ANIMALS: The study was carried out on 109 Thoroughbred racehorses from 8 training yards (3 in the United Kingdom and 5 in Australia). METHODS: Gastroscopic examination alongside a questionnaire regarding management, feeding, exercise, and health...
November 29, 2018: Journal of Veterinary Internal Medicine
Tarek Mazzawi, Gülen Arslan Lied, Dag André Sangnes, Magdy El-Salhy, Johannes R Hov, Odd Helge Gilja, Jan Gunnar Hatlebakk, Trygve Hausken
BACKGROUND: Gut microbiota alterations are important in irritable bowel syndrome (IBS). The aim was to investigate the effect of fecal microbiota transplantation (FMT) on gut microbiota and the symptoms in patients with IBS. MATERIAL AND METHODS: The study included 13 IBS patients according to Rome III criteria and 13 healthy donors. Freshly donated feces were administered to the descending part of the duodenum via a gastroscope. Feces were collected from donors and patients before FMT, and from the patients at 1, 3 and 12 weeks and donors and patients at 20/28 weeks after FMT...
2018: PloS One
Łukasz Nawacki, Agata Czyż, Piotr Bryk, Dorota Kozieł, Renata Stępień, Stanisław Głuszek
BACKGROUND: Helicobacter pylori (Hp) is classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen. Its influence on the carcinogenesis of gastric cancer has been confirmed in many researches. The conclusion is obvious- early detection and eradication of Hp can prevent the development of the disease. METHODS: The objective of the study was to analyse the clinical and practical value of Carbon-13 urea breath test (UBT) in patients hospitalized due to pain complaints in the upper abdomen and dyspeptic symptoms...
June 4, 2018: Polski Przeglad Chirurgiczny
Shu-Ling Li, Li Zhao, Zi-Kai Wang, Wen Li
BACKGROUND AND AIMS: Natural orifice transluminal endoscopic surgery (NOTES) has been established in animal models and human studies, but few clinical studies have investigated transvaginal NOTES in the diagnosis of unexplained refractory ascites. We aimed to assess the feasibility, efficacy, and safety of transvaginal NOTES for the diagnosis of unexplained ascites in female patients. METHODS: A prospective study was done involving 3 female patients with unexplained ascites...
October 31, 2018: Gastrointestinal Endoscopy
Hejun Zhang, Xueqiong Nie, Zhiqiang Song, Rongli Cui, Zhu Jin
OBJECTIVES: Gastric hyperplastic polyp (GHP) commonly arises in the abnormal surrounding mucosa, including autoimmune metaplastic atrophic gastritis (AMAG). We aimed to compare clinicopathological features in patients with GHPs associated with AMAG with those in patients with GHPs associated with non-AMAG. PATIENTS AND METHODS: A total of 1170 patients with GHP(s) were enrolled, and their clinical and pathological data were analyzed, retrospectively. RESULTS: The GHP patients were divided into 181 A-GHP (type A GHP, AMAG-associated GHP) participants, 312 B-GHP (type B GHP, Helicobacter pylori infection-associated GHP) participants, and 677 other GHP participants (non-A-GHP and non-B-GHP) based on pathological status of the surrounding non-polypoid mucosa...
October 24, 2018: Scandinavian Journal of Gastroenterology
Dingyun Liu, Nini Rao, Xinming Mei, Hongxiu Jiang, Quanchi Li, ChengSi Luo, Qian Li, Chengshi Zeng, Bing Zeng, Tao Gan
Early diagnoses of esophageal cancer can greatly improve the survival rate of patients. At present, the lesion annotation of early esophageal cancers (EEC) in gastroscopic images is generally performed by medical personnel in a clinic. To reduce the effect of subjectivity and fatigue in manual annotation, computer-aided annotation is required. However, automated annotation of EEC lesions using images is a challenging task owing to the fine-grained variability in the appearance of EEC lesions. This study modifies the traditional EEC annotation framework and utilizes visual salient information to develop a two saliency levels-based lesion annotation (TSL-BLA) for EEC annotations on gastroscopic images...
October 16, 2018: Journal of Medical Systems
Shahzad Latif, Noreen Akther, Sameen Amjed, Junaid Jafar, Bushra Saleem, Muhammad Usman, Tuaha Amjad, Waqas Maqsood, Humaira Waseem, Naim Ashraf
OBJECTIVE: To assess the effectiveness of clarithromycin based standard triple therapy verses levofloxacin based first line therapy against Helicobacter pylori infection. METHODS: This prospective observational study was performed at Akhter Saeed Trust Teaching Hospital, Lahore, from May 2016 to 31st May 2017 and comprised of all patients with positive H. pylori, confirmed by gastroscopic biopsy; fulfill the inclusion criteria of this study. Patients were divided into two groups (Group A and Group B)...
September 2018: JPMA. the Journal of the Pakistan Medical Association
Charles Eugenio McCafferty, Marra Jai Aghajani, David Abi-Hanna, Iain Bruce Gosbell, Slade Owen Jensen
INTRODUCTION: During clinical use, gastrointestinal endoscopes are grossly contaminated with patient's native flora. These endoscopes undergo reprocessing to prevent infectious transmission upon future use. Endoscopy-associated infections and outbreaks have been reported, with a recent focus on the transmission of multi-drug resistant organisms. This review aims to provide an update on endoscopy-associated infections, and the factors contributing to their occurrence. METHODS: PubMed, ScienceDirect, and CINAHL were searched for articles describing gastrointestinal endoscopy-associated infections and outbreaks published from 2008 to 2018...
October 10, 2018: Annals of Clinical Microbiology and Antimicrobials
Yangyang Ji, Tao Peng, Guoqiang Wang, Yu Zhang, Mingfu Cao, Qiang Gao, Shuguang Li
OBJECTIVE: To evaluate the short-term efficacy and safety of neoadjuvant synchronous chemoradiotherapy (paclitaxel plus carboplatin regimen) in stage III adenocarcinoma of esophagogastric junction (AEG). METHODS: Forty cases clinically diagnosed as stage III AEG were prospectively enrolled at the Department of Gastrointestinal Oncology Surgery, the First Affiliated Hospital of Hebei North University from December 2014 to November 2017 and then were randomly divided into paclitaxel plus carboplatin combined with synchronous radiotherapy group(neoadjuvant group) and direct operation group...
September 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Jing-Jing Wan, Su-Juan Fei, Sheng-Xiang Lv, Shu-Tang Han, Xing-Gang Ma, Dong-Sheng Xu, Hong-Mei Chen, Ju Zhang
The present case study aimed to evaluate the effect of gastroscopic biopsy of gastric ulcer margins and healed sites in the diagnosis of early gastric cancer. A total of 513 patients who were diagnosed with gastric ulcers using gastroscopy between January 1999 and December 2013 were included in the present study and were divided into either the experimental or the control group. In the control group, samples were only taken from the ulcer margin, whereas in the experimental group samples were taken from the ulcer margin and from the ulcer base...
October 2018: Oncology Letters
Erik Folch, Fayez Kheir, Amit Mahajan, Daniel Alape, Omar Ibrahim, Eugene Shostak, Adnan Majid
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) tube placement is a procedure frequently done in the intensive care unit. The use of a traditional endoscope can be difficult in cases of esophageal stenosis and theoretically confers an increased risk of infection due to its complex architecture. We describe a technique using the bronchoscope, which allows navigation through stenotic esophageal lesions and also minimizes the risk of endoscopy-associated infections. METHODS: Prospective series of patients who had PEG tube placement guided by a bronchoscope...
September 24, 2018: Journal of Intensive Care Medicine
Meng-Jun Chen, Wei Wu, Shuang Pan, Chun-Jing Lin, Le-Mei Dong, Zhou-Feng Chen, Jian-Sheng Wu, Zhi-Ming Huang
The detection rate of gastric polyps (GPs) is low, improving the detection rate would be good. The present study aimed to evaluate the role of sedated gastroscopy in GP detection. The data of patients who underwent gastroscopic examination from January 2014 to December 2016 at the First Affiliated Hospital of Wenzhou Medical University (Wenzhou, China) were retrospectively reviewed. Endoscopic records of 6,195 patients diagnosed with GPs were analyzed. The GP detection rate was 3.12 and 5.11% in the unsedated and sedated gastroscopy group, respectively (P<0...
October 2018: Experimental and Therapeutic Medicine
Jimin Han, Matthew Chin, Kyle J Fortinsky, Reem Sharaiha, Christopher J Gostout, Kenneth J Chang
Background and study aims  This preliminary study was conducted to determine the feasibility and safety of endoscopic augmentation of the gastroesophageal junction (GEJ) using the Apollo OverStitch endoscopic suturing system in patients with gastroesophageal reflux disease (GERD) symptoms. Patients and methods  Endoscopic augmentation of GEJ was performed on 10 consecutive patients and the data were analyzed retrospectively. Using a double-channel gastroscope affixed to the endoscopic suturing platform, interrupted sutures were placed on the gastric side of the GEJ in 2 layers in order to create a narrowed and elongated GEJ...
September 2018: Endoscopy International Open
Hongfei Cai, Rui Wang, Yang Li, Xiaodong Yang, Youbin Cui
Background: Three-dimensional (3D) reconstruction has been used in evaluating the lungs and liver, but there is only little research on the application of 3D reconstruction for the oesophagus. This research aims to study the application of 3D reconstruction in patients with lower segment oesophageal tumours to improve the diagnosis and treatment of oesophageal cancer and to provide a better method of preoperative assessment. Methods: All the patients were treated at the First Hospital of Jilin University between January 2014 and August 2015 for oesophageal cancer...
July 2018: Journal of Thoracic Disease
Zifei Tang, Jieru Shi, Min Ji, Peng Shi, Zhiheng Huang, Ying Huang
Background/Aims: Giant peptic ulcers (GPUs) are detrimental for all patients, especially for children. However, few reports have described GPUs in children. This study aims to evaluate the characteristics of GPUs in Chinese children and to identify risk factors. Patients and Methods: We retrospectively analyzed patients at the Children's Hospital of Fudan University from April 2014 to August 2017. Patients with GPUs (>2.0 cm) were included in the study, and the clinical data, pathological characteristics and presence of Helicobacter pylori (H...
August 20, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
Shunhui He, Xuehua Liu, Guoping Du, Wenzhi Chen, Weiqing Ruan
Clinical value and safety of the use of gastroscopy as oral choledochoscopy in the treatment of biliary diseases was explored. Clinical data of 55 patients with biliary diseases who underwent gastroscopy were retrospectively analyzed. The types of gastroscopy, size of duodenal papilla incision, balloon dilatation, the success rate of gastroscopy entry, depth of gastroscopy entering into bile duct, endoscopic diagnosis and postoperative complications were recorded. Simple insertion-by-hand was performed, and insertion into common bile duct was successfully achieved in 53 cases, and the overall technical success rate was 96...
August 2018: Experimental and Therapeutic Medicine
Jorge Alberto Arroyo Vázquez, Maria Bergström, Stephen Bligh, Barry P McMahon, Per-Ola Park
BACKGROUND: Perforated duodenal ulcers can be treated with a covered stent. Stent migration is a severe complication, sometimes requiring surgery. Pyloric physiology during stent treatment has not been studied and mechanisms for migration are unknown. The aim of this study was to investigate the pyloric response to distention, mimicking stent treatment, using the EndoFLIP. METHODS: A nonsurvival study in five pigs was carried out, followed by a pilot study in one volunteer...
August 15, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
C E McCafferty, D Abi-Hanna, M J Aghajani, G T Micali, I Lockart, K Vickery, I B Gosbell, S O Jensen
BACKGROUND: Endoscopic procedures are vital to gastrointestinal disease diagnosis and management, but risk infection transmission. In Australia, endoscopes undergo monthly-to-quarterly microbiological testing, to prevent patient infection. Endoscopes are used more frequently, meaning contamination may not be detected by this surveillance before infection transmission occurs. AIM: To evaluate the use of adenosine triphosphate (ATP) measurement, alongside standard microbiological cultures, in detecting endoscope contamination before high-level disinfection...
November 2018: Journal of Hospital Infection
P Zhao, D Chen, H Cheng
No abstract text is available yet for this article.
October 2018: British Journal of Biomedical Science
Lu-Jing Tang, Hong Zhao, Jin-Gan Lou, Ke-Rong Peng, Jin-Dan Yu, You-You Luo, You-Hong Fang, Fei-Bo Chen, Jie Chen
OBJECTIVE: To study the clinical features and prognosis of gastrointestinal injury caused by foreign bodies in the upper gastrointestinal tract in children. METHODS: A retrospective analysis was performed for the clinical data of 217 children who were diagnosed with foreign bodies in the upper gastrointestinal tract complicated by gastrointestinal injury by gastroscopy from January 2011 to December 2016, including clinical features, gastroscopic findings, complications, and prognosis...
July 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
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