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https://www.readbyqxmd.com/read/30118995/moderators-and-mediators-of-a-maternal-depression-treatment-study-impact-of-maternal-trauma-and-parenting-on-child-outcomes
#1
Holly A Swartz, Jill M Cyranowski, Yu Cheng, Marlissa Amole
OBJECTIVE: Treatment of maternal depression with psychotherapy has been shown to confer indirect benefits to school-age offspring with psychiatric disorders. The current study sought to understand mechanisms by which improvement in depressed mothers, with and without histories of trauma and treated with psychotherapy, produce changes in children who struggle with psychiatric illnesses themselves. We hypothesized that maternal history of childhood trauma would moderate the relationship between maternal and child outcomes and that increased positive and decreased negative parenting behaviors would mediate the relationship between maternal and child outcomes...
August 3, 2018: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/30118784/positive-impact-of-a-cooking-skills-intervention-among-brazilian-university-students-six-months-follow-up-of-a-randomized-controlled-trial
#2
Greyce Luci Bernardo, Manuela Mika Jomori, Ana Carolina Fernandes, Claudia Flemming Colussi, Margaret D Condrasky, Rossana Pacheco da Costa Proença
OBJECTIVES: The purpose of this study was to determine the effects of the Nutrition and Culinary in the Kitchen (NCK) Program to evaluate the improvement of cooking skills and healthy eating of university students. METHODS: A randomized controlled trial with six months follow-up was used incorporating an intervention group (IG) and a control group (CG). The IG participated in the NCK program over a six-week period, three hours weekly, based on five hands-on cooking classes and one food market visit, while CG continued their usual activities...
August 14, 2018: Appetite
https://www.readbyqxmd.com/read/30118640/gps-devices-in-a-simulated-mass-casualty-event
#3
Isabel T Gross, Ryan F Coughlin, David C Cone, Sandy Bogucki, Marc Auerbach, Mark X Cicero
OBJECTIVE: The aim of this study was to assess the staff perception of a global positioning system (GPS) as a patient tracking tool at an emergency department (ED) receiving patients from a simulated mass casualty event. METHODS: During a regional airport disaster drill a plane crash with 46 pediatric patients was simulated. Personnel from airport fire, municipal fire, law enforcement, emergency medical services, and emergency medicine departments were present. Twenty of the 46 patient actors required transport for medical evaluation, and we affixed GPS devices to 12 of these actors...
August 17, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/30116100/school-related-outcomes-from-a-randomized-controlled-trial-of-adolescent-depression-prevention-programs
#4
Alyssa E McCarthy, Jami F Young, Jessica S Benas, Robert J Gallop
Previous research has demonstrated the effectiveness of school-based depression prevention programs in reducing depressive symptoms and improving functioning. This study examined whether these programs have positive effects on school-related outcomes. Students at 10 middle and high schools in New Jersey were randomized to weekly sessions of Interpersonal Psychotherapy - Adolescent Skills Training (IPT-AST) or group counseling (GC). Analyses examined whether there were intervention effects on participants' grades, attendance rates, and disciplinary outcomes over approximately one year post-intervention...
September 2018: Journal of Emotional and Behavioral Disorders
https://www.readbyqxmd.com/read/30115146/an-evaluation-of-community-based-cognitive-stimulation-therapy-a-pilot-study-with-an-irish-population-of-people-with-dementia
#5
M E Kelly, S Finan, M Lawless, N Scully, J Fitzpatrick, M Quigley, F Tyrrell, A O'Regan, A Devane
OBJECTIVES: Research shows that cognitive stimulation therapy (CST) improves cognitive function, quality of life, and well-being of people with mild-moderate dementia. Despite consistent evidence and recommendations, CST is not routinely available in Ireland post-diagnosis. The aim of the current research was to develop and evaluate community-based CST for people with mild-moderate dementia, run by the Alzheimer Society of Ireland across four pilot sites in Ireland. METHODS: Participants with mild-moderate dementia attended once weekly CST sessions for 14 weeks...
September 2017: Irish Journal of Psychological Medicine
https://www.readbyqxmd.com/read/30113451/the-utility-of-fdg-pet-ct-imaging-in-the-evaluation-of-multicentric-reticulohistiocytosis-a-case-report
#6
Tomoyuki Asano, Ken Suzutani, Aya Watanabe, Aki Honda, Natsumi Mori, Makiko Yashiro, Shuzo Sato, Hiroko Kobayashi, Hiroshi Watanabe, Momoko Hazama, Takashi Kanno, Eiji Suzuki, Shiro Ishii, Kiyoshi Migita
INTRODUCTION: Multicentric reticulohistiocytosis (MRH) is a rare histiocytic disorder that involves the skin, joints, and visceral organs. CASE PRESENTATION: We report a 67-year-old woman with MRH who presented with a 2-years history of polyarthralgia and skin nodules. Her symptoms were an inflammatory polyarthropathy with punched-out lesions of the distal interphalangeal (DIP) joints of both hands. Doppler ultrasonography of the hands showed large bone erosions with power Doppler signals in the DIP joints...
August 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30113141/anogenital-distance-and-reproductive-outcomes-in-9-to-11-year-old-boys-the-inma-granada-cohort-study
#7
C Freire, O Ocón-Hernández, C Dávila-Arias, R Pérez-Lobato, I Calvente, R Ramos, N Olea, M F Fernández
BACKGROUND: Studies examining the association of anogenital distance (AGD), a biomarker of prenatal androgen exposure, with sexual development in children are lacking. OBJECTIVE: To assess the association between AGD measures and reproductive outcomes, including puberty onset, testicular volume, reproductive hormone levels, and urogenital malformations in boys aged 9-11 years. MATERIALS AND METHODS: A cross-sectional study was conducted among children belonging to the Spanish Environment and Childhood (INMA) Project, a population-based birth cohort study...
August 16, 2018: Andrology
https://www.readbyqxmd.com/read/30112671/the-brain-adipocyte-gut-network-linking-obesity-and-depression-subtypes
#8
REVIEW
Carla M Patist, Nicolas J C Stapelberg, Eugene F Du Toit, John P Headrick
Major depressive disorder (MDD) and obesity are dominant and inter-related health burdens. Obesity is a risk factor for MDD, and there is evidence MDD increases risk of obesity. However, description of a bidirectional relationship between obesity and MDD is misleading, as closer examination reveals distinct unidirectional relationships in MDD subtypes. MDD is frequently associated with weight loss, although obesity promotes MDD. In contrast, MDD with atypical features (MDD-AF) is characterised by subsequent weight gain and obesity...
August 15, 2018: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/30111973/real-world-patient-and-caregiver-reported-outcomes-in-advanced-breast-cancer
#9
V Lambert-Obry, A Gouault-Laliberté, A Castonguay, G Zanotti, T Tran, M Mates, J Lemieux, P Chabot, C Prady, F Couture, J Lachaine
Background: Advanced breast cancer (abc) represents a substantial burden for patients and caregivers. In the present study, we aimed to estimate quality of life (qol), utility, productivity loss, pain, health care resource utilization, and costs for patients with abc, and qol, utility, and productivity loss for their caregivers. Methods: This multicentre prospective non-interventional study was conducted in Canada. Eligible participants were postmenopausal women with estrogen receptor-positive, her2-negative unresectable abc and their caregivers...
August 2018: Current Oncology
https://www.readbyqxmd.com/read/30111174/hiv-serostatus-disclosure-in-the-democratic-republic-of-the-congo-a-systematic-review
#10
Guy-Lucien Whembolua, Donaldson F Conserve, Kirstyn Thomas, Daudet Ilunga Tshiswaka, Lara Handler
HIV status disclosure among people living with HIV/AIDS has been shown to have a number of both personal and public health benefits, but rates of HIV status disclosure remain low in many African countries, including the Democratic Republic of the Congo (DRC). This systematic review uses the Disclosure Process Model to examine the factors involved in serostatus disclosure and nondisclosure to various persons in the lives of people living with HIV/AIDS (PLWHA) in the DRC, as well as the specific outcomes of their disclosure or nondisclosure...
August 15, 2018: AIDS Care
https://www.readbyqxmd.com/read/30109483/icud-siu-international-consultation-on-bladder-cancer-2017-management-of-non-muscle-invasive-bladder-cancer
#11
REVIEW
Leonardo L Monteiro, J Alfred Witjes, Piyush K Agarwal, Christopher B Anderson, Trinity J Bivalacqua, Bernard H Bochner, Joost L Boormans, Sam S Chang, Jose L Domínguez-Escrig, James M McKiernan, Colin Dinney, Guilherme Godoy, Girish S Kulkarni, Paramananthan Mariappan, Michael A O'Donnell, Cyrill A Rentsch, Jay B Shah, Eduardo Solsona, Robert S Svatek, Antoine G van der Heijden, F Johannes P van Valenberg, Wassim Kassouf
PURPOSE: To provide a summary of the Third International Consultation on Bladder Cancer recommendations for the management of non-muscle invasive bladder cancer (NMIBC). METHODS: A detailed review of the literature was performed focusing on original articles for the management of NMIBC. An international committee assessed and graded the articles based on the Oxford Centre for Evidence-based Medicine system. The entire spectrum of NMIBC was covered such as prognostic factors of recurrence and progression, risk stratification, staging, management of positive urine cytology with negative white light cystoscopy, indications of bladder and prostatic urethral biopsies, management of Ta low grade (LG) and high risk tumors (Ta high grade [HG], T1, carcinoma in situ [CIS]), impact of BCG strain and host on outcomes, management of complications of intravesical therapy, role of alternative therapies, indications for early cystectomy, surveillance strategies, and new treatments...
August 14, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/30109053/flexible-decision-making-in-grooming-partner-choice-in-sooty-mangabeys-and-chimpanzees
#12
Alexander Mielke, Anna Preis, Liran Samuni, Jan F Gogarten, Roman M Wittig, Catherine Crockford
Living in permanent social groups forces animals to make decisions about when, how and with whom to interact, requiring decisions to be made that integrate multiple sources of information. Changing social environments can influence this decision-making process by constraining choice or altering the likelihood of a positive outcome. Here, we conceptualized grooming as a choice situation where an individual chooses one of a number of potential partners. Studying two wild populations of sympatric primate species, sooty mangabeys ( Cercocebus atys atys ) and western chimpanzees ( Pan troglodytes verus ), we tested what properties of potential partners influenced grooming decisions, including their relative value based on available alternatives and the social relationships of potential partners with bystanders who could observe the outcome of the decision...
July 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/30108343/vitamin-d-and-associated-perinatal-neonatal-outcomes-among-extremely-low-birth-weight-infants
#13
Birju A Shah, James F Padbury, Michael P Anderson, Michael F Holick, Edgardo Szyld, Catherine M Gordon
OBJECTIVE: To evaluate vitamin D inadequacy among extremely low-birth-weight (ELBW, <1000 g) infants and the association between circulating vitamin D concentrations and perinatal-neonatal outcomes. STUDY DESIGN: Prospective cohort study of ELBW infants in the neonatal ICU. Blood was collected within the first 3 days after birth after obtaining informed consent. Circulating 25-hydroxyvitamin D concentrations (25(OH)D) were quantified using liquid chromatography-tandem mass spectroscopy and classified as vitamin D deficient, insufficient, or adequate ( < 20, 20-30, or > 30 ng/mL, respectively)...
August 14, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/30105967/molecular-detection-of-residual-parasitemia-after-pyronaridine-artesunate-or-artemether-lumefantrine-treatment-of-uncomplicated-plasmodium-falciparum-malaria-in-kenyan-children
#14
Johanna M Roth, Patrick Sawa, George Omweri, Nicodemus Makio, Victor Osoti, Menno D de Jong, Henk D F H Schallig, Pètra F Mens
Artemisinin resistance is rapidly rising in Southeast Asia and may spread to African countries, where efficacy estimates are currently still excellent. Extensive monitoring of parasite clearance dynamics after treatment is needed to determine whether responsiveness to artemisinin-based combination therapies (ACT) is changing in Africa. In this study, Kenyan children with uncomplicated falciparum malaria were randomly assigned to pyronaridine-artesunate (PA) or artemether-lumefantrine (AL) treatment. Parasite clearance was evaluated over 7 days following the start of treatment by qPCR and direct-on-blood PCR nucleic acid lateral flow immunoassay (db-PCR-NALFIA), a simplified molecular malaria diagnostic...
August 13, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/30105915/treatment-complexities-among-patients-with-tuberculosis-in-a-high-hiv-prevalence-cohort-in-the-united-states
#15
Destani Bizune, Russell Kempker, Michelle Kagei, Aliya Yamin, Omar Mohamed, David P Holland, Alawode Oladele, Yun F Wang, Paulina A Rebolledo, Henry Blumberg, Susan M Ray, Marcos C Schechter
The association between human immunodeficiency virus (HIV) infection and tuberculosis (TB) mortality has been studied extensively, but the impact of HIV on other clinically relevant aspects of TB care such as TB drug-related adverse events (AE), hospital readmissions, and TB treatment duration is less well characterized. We describe the association of HIV infection with TB clinical complexities and outcomes in a high HIV prevalence cohort in the United States. This is a retrospective cohort study among patients treated for culture-confirmed TB between 2008-2015 at an inner-city hospital in Atlanta, GA...
August 14, 2018: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/30104315/a-call-for-applied-knowledge-and-lived-interdisciplinarity-in-the-medical-care-of-depressed-employees-a-cross-sectional-survey-with-german-occupational-physicians-and-psychotherapists
#16
Lina Nassri, Isabell Schneider, Petra Maria Gaum, Jessica Lang
OBJECTIVES: To identify approaches for an effective patient-centred care of depressed employees, we investigated occupational physicians' (OPs) and psychotherapists' (PTs) knowledge about job stressors on the development of depression, application of this knowledge, interdisciplinary cooperation and perceived barriers. STUDY DESIGN: A cross-sectional online survey. PARTICIPANTS: OPs (163; 48.5% male) and PTs (69; 43.5% male) providing complete data on the survey out of 257 OPs and 112 PTs who started the survey...
August 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/30103980/long-term-effectiveness-of-one-and-two-doses-of-a-killed-bivalent-whole-cell-oral-cholera-vaccine-in-haiti-an-extended-case-control-study
#17
Molly F Franke, Ralph Ternier, J Gregory Jerome, Wilfredo R Matias, Jason B Harris, Louise C Ivers
BACKGROUND: No study of long-term protection following killed oral cholera vaccination has been done outside of the historically cholera-endemic areas of south Asia, or has examined protection after a single-dose vaccination regimen. To address this, we examined the duration of protection of the standard two-dose regimen and an incomplete regimen of one dose up to 4 years after vaccination in Haiti. METHODS: In the setting of two-dose vaccination campaigns with a killed, bivalent, whole-cell oral cholera vaccination, we did a case-control study from October, 2012 through November, 2016...
September 2018: Lancet Global Health
https://www.readbyqxmd.com/read/30102562/clinical-significance-of-the-post-radiotherapy-18-f-fluorodeoxyglucose-positron-emission-tomography-response-in-nasopharyngeal-cancer
#18
Yuri Jeong, In-Hye Jung, Jae Seung Kim, Sang-Wook Lee, Sei-Kyung Chang
OBJECTIVE: The aim of the present study was to evaluate the clinical significance of the post-radiotherapy 18 F-fluorodeoxyglucose positron emission tomography (18 F-FDG PET) response for detecting residual disease and predicting survival outcome in patients with nasopharyngeal cancer. METHODS: We reviewed 143 patients with nasopharyngeal cancer who underwent 18 F-FDG PET within 6 months after completion of radiotherapy between 2001 and 2012. 18 F-FDG PET findings at the primary tumor (T-) and regional lymph nodes (N-) were separately assessed and considered negative [PET (-)] or positive [PET (+)] depending on the remaining focal increased uptake of 18 F-FDG that was greater than that of the surrounding muscle or blood vessels...
August 13, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/30100403/epigenetic-prediction-of-response-to-anti-pd-1-treatment-in-non-small-cell-lung-cancer-a-multicentre-retrospective-analysis
#19
Michäel Duruisseaux, Anna Martínez-Cardús, Maria E Calleja-Cervantes, Sebastian Moran, Manuel Castro de Moura, Veronica Davalos, David Piñeyro, Montse Sanchez-Cespedes, Nicolas Girard, Marie Brevet, Etienne Giroux-Leprieur, Coraline Dumenil, Monica Pradotto, Paolo Bironzo, Enrica Capelletto, Silvia Novello, Alexis Cortot, Marie-Christine Copin, Niki Karachaliou, Maria Gonzalez-Cao, Sergio Peralta, Luis M Montuenga, Ignacio Gil-Bazo, Iosune Baraibar, Maria D Lozano, Mar Varela, Jose C Ruffinelli, Ramon Palmero, Ernest Nadal, Teresa Moran, Lidia Perez, Immaculada Ramos, Qingyang Xiao, Agustin F Fernandez, Mario F Fraga, Marta Gut, Ivo Gut, Cristina Teixidó, Noelia Vilariño, Aleix Prat, Noemi Reguart, Amparo Benito, Pilar Garrido, Isabel Barragan, Jean-François Emile, Rafael Rosell, Elisabeth Brambilla, Manel Esteller
BACKGROUND: Anti-programmed death-1 (PD-1) treatment for advanced non-small-cell lung cancer (NSCLC) has improved the survival of patients. However, a substantial percentage of patients do not respond to this treatment. We examined the use of DNA methylation profiles to determine the efficacy of anti-PD-1 treatment in patients recruited with current stage IV NSCLC. METHODS: In this multicentre study, we recruited adult patients from 15 hospitals in France, Spain, and Italy who had histologically proven stage IV NSCLC and had been exposed to PD-1 blockade during the course of the disease...
August 9, 2018: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/30099584/risk-stratification-in-patients-with-complicated-parapneumonic-effusions-and-empyema-using-the-rapid-score
#20
Sunkaru Touray, Rahul N Sood, Daniel Lindstrom, Jonathan Holdorf, Sumera Ahmad, Daniel B Knox, Andres F Sosa
PURPOSE: Complicated parapneumonic effusions and empyema are a leading cause of morbidity in the United States with over 1 million admissions annually and a mortality rate that remains high in spite of recent advances in diagnosis and treatment. The identification of high risk patients is crucial for improved management and the provision of cost-effective care. The RAPID score is a scoring system comprised of the following variables: renal function, age, purulence, infection source, and dietary factors and has been shown to predict outcomes in patients with pleural space infections...
August 11, 2018: Lung
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